- Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladderKunyoo Shin
Department of Developmental Biology, Institute for Stem Cell Biology and Regenerative Medicine, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA
Nature 472:110-4. 2011..Our findings provide a conceptual framework for injury-induced epithelial regeneration in endodermal organs, and may provide a basis for understanding the roles of signalling pathways in cancer growth and metastasis...
- Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinomaKunyoo Shin
Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
Nat Cell Biol 16:469-78. 2014..We thus find that invasive carcinoma is initiated from basal urothelial stem cells but that tumour cell phenotype can diverge significantly from that of the cancer cell of origin. ..