Kunyoo Shin

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
    Kunyoo Shin
    Department of Developmental Biology, Institute for Stem Cell Biology and Regenerative Medicine, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 472:110-4. 2011
  2. pmc Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate
    Agnes Lim
    1 Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA 2 Department of Developmental Biology, Stanford University School of Medicine, Stanford, California 94305, USA 3 Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Cell Biol 16:1135-45. 2014
  3. pmc Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma
    Kunyoo Shin
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Cell Biol 16:469-78. 2014
  4. pmc Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors
    Kunyoo Shin
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA Electronic address
    Cancer Cell 26:521-33. 2014

Collaborators

Detail Information

Publications4

  1. pmc Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
    Kunyoo Shin
    Department of Developmental Biology, Institute for Stem Cell Biology and Regenerative Medicine, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 472:110-4. 2011
    ..Our findings provide a conceptual framework for injury-induced epithelial regeneration in endodermal organs, and may provide a basis for understanding the roles of signalling pathways in cancer growth and metastasis...
  2. pmc Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate
    Agnes Lim
    1 Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA 2 Department of Developmental Biology, Stanford University School of Medicine, Stanford, California 94305, USA 3 Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Cell Biol 16:1135-45. 2014
    ..Prostate tubule branching thus may be initiated from regions of low Hh pathway activity, with implications for the prostatic hyperplasia commonly observed in late adulthood. ..
  3. pmc Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma
    Kunyoo Shin
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Cell Biol 16:469-78. 2014
    ..We thus find that invasive carcinoma is initiated from basal urothelial stem cells but that tumour cell phenotype can diverge significantly from that of the cancer cell of origin. ..
  4. pmc Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors
    Kunyoo Shin
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA Electronic address
    Cancer Cell 26:521-33. 2014
    ..Progression is dramatically reduced by pharmacological activation of BMP pathway activity with low-dose FK506, suggesting an approach to management of human bladder cancer. ..