Research Topics
| J I SheikhSummaryAffiliation: Stanford University Country: USA Publications
Research Grants
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Detail Information
Publications
Efficacy, safety, and tolerability of sertraline in patients with late-life depression and comorbid medical illnessJavaid I Sheikh
Stanford University School of Medicine, Stanford, California Veterans Affairs Palo Alto Health Care System, Menlo Park, California 94305, USA
J Am Geriatr Soc 52:86-92. 2004..To report on the efficacy, safety, and tolerability of sertraline in the treatment of elderly depres-sed patients with and without comorbid medical illness...- Sleep in post-traumatic stress disorder and panic: convergence and divergenceJavaid I Sheikh
Veterans Affairs Palo Alto Healthcare System 116A MP, Menlo Park, California 94025, USA
Depress Anxiety 18:187-97. 2003..Additionally, such sleep studies have the potential to provide important insights into ongoing efforts to develop a cohesive conceptual framework into the patho-physiologies of these disorders... - Aging and panic disorder: phenomenology, comorbidity, and risk factorsJavaid I Sheikh
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5723, USA
Am J Geriatr Psychiatry 12:102-9. 2004..The authors compared young and older adults with panic disorder (PD) to investigate differences in panic-associated phenomenology, psychiatric comorbidity, and risk factors... - The efficacy of sertraline in panic disorder: combined results from two fixed-dose studiesJ I Sheikh
Department of Psychiatry, Stanford University School of Medicine, CA 94305 5723, USA
Int Clin Psychopharmacol 15:335-42. 2000..The presence of mild-to-moderate subsyndromic levels of depression did not reduce the anti-panic efficacy of sertraline... - Effects of comorbid diagnoses on sleep disturbance in PTSDGregory A Leskin
VA Palo Alto Health Care System 116A MP, 795 Willow Road, Menlo Park, CA 94025, USA
J Psychiatr Res 36:449-52. 2002..This study tested the hypothesis that PTSD patients suffer a greater proportion of sleep problems according to comorbid diagnoses... - A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementiasJ W Hawkins
VA Palo Alto Health Care System, Mental Illness Research, Educational and Clinical Center, Menlo Park, CA 94205, USA
Am J Geriatr Psychiatry 8:221-5. 2000..Two of the 24 patients discontinued use of the medication because of excessive sedation. No other significant side effects were noted in treatment lasting up to 2 years... - Pre-intervention assessment for disruptive behavior problems: a focus on staff needsE L Cassidy
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, USA
Aging Ment Health 6:166-71. 2002..Although the time required is great, frontline staff are adept at utilizing less invasive interventions first. Implications for subsequent interventions, need for continued evaluation and reassessing levels of staff burden are discussed... - Divalproex for the treatment of geriatric bipolar disorderD J Mordecai
Stanford University School of Medicine, Stanford, California 94305, USA
Int J Geriatr Psychiatry 14:494-6. 1999..Of the six, five showed some improvement with divalproex alone or in combination with other agents. Clearly, a double-blind, placebo-controlled study is an important next step to assess this promising medication... - VA practice patterns and practice guidelines for treating posttraumatic stress disorderCraig S Rosen
National Center for PTSD, Veterans Affairs Palo Alto Health Care System, Palo Alto, California, USA
J Trauma Stress 17:213-22. 2004..Exposure therapy was rarely used. Additional research is needed on training, clinical resources, and organizational factors that may influence VA implementation of guideline recommendations... - Age differences in symptoms of depression and anxiety: examining behavioral medicine outpatientsJennifer H Goldberg
Stanford Center for Research in Disease Prevention, Stanford University School of Medicine, Palo Alto, California, USA
J Behav Med 26:119-32. 2003..these results suggest the importance of assessing cognitive-affective depressive symptoms in both older and younger male medical outpatients... - Physical and sexual abuse history and addiction treatment outcomesCraig S Rosen
National Center for PTSD and Center for Health Care Evaluation, Department of Veterans Affairs, 795 Willow Road 352 117, Menlo Park, California 94025, USA
J Stud Alcohol 63:683-7. 2002..The present study sought to determine whether physical or sexual abuse also predicted treatment response (posttreatment outcomes) of individuals with substance use disorders... - Mixed anxiety and depression in older adults: clinical characteristics and managementErin L Cassidy
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, USA
J Geriatr Psychiatry Neurol 18:83-8. 2005..Further double-blind, randomized investigations with newer antidepressant medications are required to extend these preliminary findings with nefazodone... - How well are clinicians following dementia practice guidelines?Craig S Rosen
VA Sierra Pacific Mental Illness Research, Education and Clinical Center, Center for Health Care Evaluation, VA Palo Alto Health Care System, Menlo Park, CA 94025, USA
Alzheimer Dis Assoc Disord 16:15-23. 2002..These results suggest possible priorities for quality improvement efforts. Further research is needed to clarify reasons for particular gaps between guidelines and practice and to identify specific targets for intervention... - Underreporting of behavioral problems in older hospitalized patientsHelen D Davies
Veterans Affairs Palo Alto Health Care System, 3801 Miranda Avenue, 116F, Palo Alto, CA 94304, USA
Gerontologist 45:535-8. 2005..Such underreporting may have clinical and administrative implications... - Anxiety disorders in the elderly: DSM-IV and other barriers to diagnosis and treatmentB W Palmer
University of California, San Diego and San Diego VA Medical Center, Department of Psychiatry, 92161, USA
J Affect Disord 46:183-90. 1997..An open-minded approach unhinged by 'conventional wisdom' is warranted... - Anxiety in older adults. Assessment and management of three common presentationsJavaid I Sheikh
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, USA
Geriatrics 58:44-5. 2003 - Lifetime trauma history and panic disorder: findings from the National Comorbidity SurveyGregory A Leskin
Stanford University School of Medicine, VA Palo Alto Health Care System, Menlo Park, CA 94025, USA
J Anxiety Disord 16:599-603. 2002..CONCLUSIONS: These results suggest that trauma may act as a risk factor for panic disorder, as well as comorbid panic disorder and PTSD... - Tardive dyskinesia and steady-state serum levels of thiothixeneJ A Yesavage
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305
Arch Gen Psychiatry 44:913-5. 1987..This relationship was independent of the relationship between tardive dyskinesia and age... - Gender differences in panic disorder: findings from the National Comorbidity SurveyJavaid I Sheikh
VA Palo Alto Health Care System, Menlo Park, CA 94025, USA
Am J Psychiatry 159:55-8. 2002..The pathophysiology of these symptom differences may involve gender differences in sensitivity to CO(2) and in the threshold for panic attacks during hypoxic and hypercapnic states... 
Posttraumatic stress and aggression among veterans in long-term careEve B Carlson
National Center for Posttraumatic Stress Disorder, Department of Veterans Affairs, Menlo Park, California 94025, USA
J Geriatr Psychiatry Neurol 21:61-71. 2008..These findings are consistent with the hypothesis that posttraumatic symptoms can contribute to aggressive behaviors in elderly, medically ill, and cognitively impaired patients...- Tolerability and effectiveness of lamotrigine in complex elderly patientsJasdeep S Aulakh
VA Palo Alto Health Care System and Mental Illness Research, Educational and Clinical Center and Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Menlo Park, CA 94025, USA
J Geriatr Psychiatry Neurol 18:8-11. 2005..These results support the authors' belief that controlled clinical investigations of this medication should be performed... - Posttraumatic stress disorder and current relationship functioning among World War II ex-prisoners of warJoan M Cook
Department of Psychiatry, University of Pennsylvania and Philadelphia VA Medical Center, 19104, USA
J Fam Psychol 18:36-45. 2004..Emotional numbing was significantly associated with relationship difficulties independent of other symptom complexes and severity of PTSD. Implications for clinical practice are discussed... - Anxiety disorders in older adultsSean A Lauderdale
Mental Illness Research, Education, and Clinical Center MIRECC, Veteran s Affairs Palo Alto Health Care System, 795 Willow Road, 116A MPD, Menlo Park, CA 94025, USA
Clin Geriatr Med 19:721-41. 2003..Collaborative care models that address physician, patient, and healthcare service delivery barriers, also hold promise for adequately treating anxiety disorders experienced by older adults... - Subclinical anxiety symptoms, sleep, and daytime dysfunction in older adults with primary insomniaAdam P Spira
University of California, San Francisco, Department of Medicine, Division of Geriatrics, San Francisco, CA, USA
J Geriatr Psychiatry Neurol 21:56-60. 2008..Thus, subclinical anxiety symptoms may be an important target for clinical intervention to improve sleep and functioning in older adults with primary insomnia.".. - Hippocampal volume, PTSD, and alcoholism in combat veteransSteven H Woodward
National Center for PTSD, Clinical Laboratory and Education Division, Mail Code 334 PTSD, VA Palo Alto HCS, 3801 Miranda Ave, Palo Alto, CA 94304, USA
Am J Psychiatry 163:674-81. 2006..Further examination of the role of alcoholism and other comorbid conditions in studies of brain structure and function in PTSD appears warranted... - Assessment of trauma exposure and post-traumatic stress in long-term care veterans: preliminary data on psychometrics and post-traumatic stress disorder prevalenceJoan M Cook
School of Medicine, Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Mil Med 170:862-6. 2005..The need for assessment and treatment of trauma exposure and PTSD in Veterans Affairs long-term care settings is emphasized... - Sleep respiratory concomitants of comorbid panic and nightmare complaint in post-traumatic stress disorderSteven H Woodward
National Center for PTSD, Clinical Laboratory and Education Division, Veterans Administration Palo Alto Health Care System, California, USA
Depress Anxiety 18:198-204. 2003..These finding are discussed in light of known telencephalic regulatory influences upon respiration rate... - Interaction of sleep disturbances and anxiety in later life: perspectives and recommendations for future researchAdam P Spira
Veterans Affairs Palo Alto Health Care System, CA 94025, USA
J Geriatr Psychiatry Neurol 18:109-15. 2005..This is followed by a brief discussion of the impact of medical illness on both anxiety and sleep disturbances. The article ends with a summary of findings from this review and provides recommendations for future research... - Efficacy of sertraline for panic disorder in older adults: a preliminary open-label trialJavaid I Sheikh
Am J Geriatr Psychiatry 12:230. 2004 - Movement during sleep: associations with posttraumatic stress disorder, nightmares, and comorbid panic disorderSteven H Woodward
National Center for PTSD, Clinical Laboratory and Education Division, VA Palo Alto Health Care System, Palo Alto, CA, USA
Sleep 25:681-8. 2002..To corroborate findings from the National Comorbidy study with objective sleep data... - Brain, skull, and cerebrospinal fluid volumes in adult posttraumatic stress disorderSteven H Woodward
National Center for PTSD, Clinical Laboratory and Education Division and Psychology Service, VA Palo Alto Healthcare System, Palo Alto, CA 94025, USA
J Trauma Stress 20:763-74. 2007..These findings co-occurred with expected effects of alcoholism and aging on cerebral tissue and CSF volumes. The results point to early developmental divergences between groups with and without PTSD following adult trauma... - Investigations of anxiety in older adults: recent advances and future directionsJavaid I Sheikh
J Geriatr Psychiatry Neurol 18:59-60. 2005
Research Grants
- Sleep in PTSD/Panic: A Multimodal Naturalistic StudyJavaid Sheikh; Fiscal Year: 2006..The proposed methods represent an advanced approach to naturalistic sleep data acquisition, combining an initial phase of ambulatory polysomnography (PSG) with extended (21+days) actigraphy and auditory sonography. ..
- Light Treatment for Sleep/Wake Disturbances ADJerome Yesavage; Fiscal Year: 2007..Outcome will be documented by objective circadian activity rhythm parameters and standard sleep/wake measures both assessed by actigraphy. ..