Curt Scharfe

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Mapping gene associations in human mitochondria using clinical disease phenotypes
    Curt Scharfe
    Stanford Genome Technology Center, Stanford University, Palo Alto, California, USA
    PLoS Comput Biol 5:e1000374. 2009
  2. pmc High-quality DNA sequence capture of 524 disease candidate genes
    Peidong Shen
    Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 108:6549-54. 2011
  3. ncbi request reprint Systematic screen for human disease genes in yeast
    Lars M Steinmetz
    Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Genet 31:400-4. 2002
  4. pmc SRMA: an R package for resequencing array data analysis
    Nianxiang Zhang
    Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA
    Bioinformatics 28:1928-30. 2012
  5. pmc A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system
    Ulrich Schlecht
    Stanford Genome Technology Center, Department of Biochemistry, Stanford University, 855 S California Avenue, Palo Alto, CA 94304, USA
    BMC Genomics 15:263. 2014
  6. pmc Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing
    Wenyi Wang
    Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA
    Nucleic Acids Res 39:44-58. 2011

Detail Information

Publications6

  1. pmc Mapping gene associations in human mitochondria using clinical disease phenotypes
    Curt Scharfe
    Stanford Genome Technology Center, Stanford University, Palo Alto, California, USA
    PLoS Comput Biol 5:e1000374. 2009
    ..The accompanying knowledgebase (http://www.mitophenome.org/) supports the study of clinical diseases and associated genes...
  2. pmc High-quality DNA sequence capture of 524 disease candidate genes
    Peidong Shen
    Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 108:6549-54. 2011
    ..This shows the ability of LPPs to accurately preserve a sample's genome information and provides a cost-effective strategy to identify both single nucleotide changes and structural variants in targeted resequencing...
  3. ncbi request reprint Systematic screen for human disease genes in yeast
    Lars M Steinmetz
    Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Genet 31:400-4. 2002
    ..To apply these advantages to human disorders involving mitochondria, human orthologs were identified and linked to heritable diseases using genomic map positions...
  4. pmc SRMA: an R package for resequencing array data analysis
    Nianxiang Zhang
    Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA
    Bioinformatics 28:1928-30. 2012
    ..The entire workflow is efficient and identifies rare DNA single nucleotide variations and structural changes such as gene deletions with high accuracy and sensitivity...
  5. pmc A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system
    Ulrich Schlecht
    Stanford Genome Technology Center, Department of Biochemistry, Stanford University, 855 S California Avenue, Palo Alto, CA 94304, USA
    BMC Genomics 15:263. 2014
    ..Understanding how cells maintain optimal copper levels is therefore highly relevant to human health...
  6. pmc Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing
    Wenyi Wang
    Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA
    Nucleic Acids Res 39:44-58. 2011
    ..Some patients carried rare heterozygous variants in several functionally interacting genes, which could indicate synergistic genetic effects in these clinically similar disorders...