Tohru Sato

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Role for CXCR6 in recruitment of activated CD8+ lymphocytes to inflamed liver
    Tohru Sato
    Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Immunol 174:277-83. 2005
  2. ncbi request reprint Short-term homing assay reveals a critical role for lymphocyte function-associated antigen-1 in the hepatic recruitment of lymphocytes in graft-versus-host disease
    Tohru Sato
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, and the Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
    J Hepatol 44:1132-40. 2006
  3. ncbi request reprint CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium
    Tracy L Staton
    Program in Immunology, Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Immunol 7:482-8. 2006
  4. pmc CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease
    Husein Hadeiba
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Immunol 9:1253-60. 2008
  5. pmc Lymphocyte electrotaxis in vitro and in vivo
    Francis Lin
    Laboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA 94305, USA
    J Immunol 181:2465-71. 2008
  6. ncbi request reprint Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon
    Amjid A Riaz
    Department of Surgery, Malmo University Hospital, Lund University, Malmo, Sweden
    FASEB J 18:881-3. 2004
  7. pmc Interleukin-10 mediates the protective effect of Linomide by reducing CXC chemokine production in endotoxin-induced liver injury
    Xiang Li
    Department of Surgery, Malmo University Hospital, Lund University, Sweden
    Br J Pharmacol 143:865-71. 2004
  8. ncbi request reprint Critical role of CXC chemokines in endotoxemic liver injury in mice
    Xiang Li
    Department of Surgery, Malmo University Hospital, Lund University, Sweden
    J Leukoc Biol 75:443-52. 2004
  9. pmc Staphylococcal enterotoxin A-induced hepatotoxicity is predominantly mediated by Fas ligand (CD95L)
    Daniel Klintman
    Department of Surgery, Malmo University Hospital, Lund University, S 205 02 Malmo, Sweden
    Ann Surg 240:1065-72; discussion 1072-3. 2004

Research Grants

Detail Information

Publications9

  1. ncbi request reprint Role for CXCR6 in recruitment of activated CD8+ lymphocytes to inflamed liver
    Tohru Sato
    Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Immunol 174:277-83. 2005
    ..We conclude that CXCR6 helps mediate the recruitment of activated CD8 lymphocytes in GvHD-induced hepatitis and may be a useful target to treat pathological inflammation in the liver...
  2. ncbi request reprint Short-term homing assay reveals a critical role for lymphocyte function-associated antigen-1 in the hepatic recruitment of lymphocytes in graft-versus-host disease
    Tohru Sato
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, and the Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
    J Hepatol 44:1132-40. 2006
    ..Although adhesive mechanisms have been implicated in the biology of GvHD hepatitis, the identity of homing receptors involved in the initial recruitment of cells from the blood is not known...
  3. ncbi request reprint CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium
    Tracy L Staton
    Program in Immunology, Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Immunol 7:482-8. 2006
    ..These studies challenge the present understanding of naive alphabeta T cell trafficking and suggest that RTEs may be involved in maintaining a diverse immune repertoire at mucosal surfaces...
  4. pmc CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease
    Husein Hadeiba
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Immunol 9:1253-60. 2008
    ..Our results identify a highly immunosuppressive population of pDCs present in lymphoid tissues...
  5. pmc Lymphocyte electrotaxis in vitro and in vivo
    Francis Lin
    Laboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA 94305, USA
    J Immunol 181:2465-71. 2008
    ..Lymphocyte positioning within tissues can thus be manipulated by externally applied electric fields, and may be influenced by endogenous electrical potential gradients as well...
  6. ncbi request reprint Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon
    Amjid A Riaz
    Department of Surgery, Malmo University Hospital, Lund University, Malmo, Sweden
    FASEB J 18:881-3. 2004
    ..Thus, it is suggested that Ang II is a major target to control pathological inflammation in the colon...
  7. pmc Interleukin-10 mediates the protective effect of Linomide by reducing CXC chemokine production in endotoxin-induced liver injury
    Xiang Li
    Department of Surgery, Malmo University Hospital, Lund University, Sweden
    Br J Pharmacol 143:865-71. 2004
    ....
  8. ncbi request reprint Critical role of CXC chemokines in endotoxemic liver injury in mice
    Xiang Li
    Department of Surgery, Malmo University Hospital, Lund University, Sweden
    J Leukoc Biol 75:443-52. 2004
    ..Indeed, these findings demonstrate that interference with MIP-2 and KC functions protects against septic liver damage and may constitute a potential therapeutic strategy to control pathological inflammation in endotoxemia...
  9. pmc Staphylococcal enterotoxin A-induced hepatotoxicity is predominantly mediated by Fas ligand (CD95L)
    Daniel Klintman
    Department of Surgery, Malmo University Hospital, Lund University, S 205 02 Malmo, Sweden
    Ann Surg 240:1065-72; discussion 1072-3. 2004
    ..To determine the role of tumor necrosis factor alpha (TNF-alpha) and Fas ligand (FasL, CD95L) in superantigen-induced and endotoxin-induced liver injury...

Research Grants1

  1. CXCR3 in Liver Lymphocyte Trafficking in GVHD Hepatitis
    Tohru Sato; Fiscal Year: 2006
    ..By using the methods established from my studies of CXCR6, I plan to characterize the role of CXCR3 and its interplay with CXCR6 as liver homing molecules and possible therapeutic targets. ..