M M Sarwal

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Immunosuppression minimization in pediatric transplantation
    M Sarwal
    Department of Pediatrics, Stanford University, Palo Alto, CA, USA
    Am J Transplant 7:2227-35. 2007
  2. pmc In praise of arrays
    Lihua Ying
    Department of Pediatrics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
    Pediatr Nephrol 24:1643-59; quiz 1655, 1659. 2009
  3. doi request reprint Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury
    Tara K Sigdel
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    J Am Soc Nephrol 23:750-63. 2012
  4. doi request reprint The yin and yang of B cells in graft rejection and tolerance
    Valeriya Zarkhin
    Department of Pediatrics, Stanford University, Stanford, CA, USA
    Transplant Rev (Orlando) 24:67-78. 2010
  5. pmc Biomarkers in solid organ transplantation: establishing personalized transplantation medicine
    Silke Roedder
    Department of Pediatrics and Immunology, Stanford University, G306 300 Pasteur Drive, Palo Alto, CA 94304, USA
    Genome Med 3:37. 2011
  6. pmc Deconvoluting the 'omics' for organ transplantation
    Minnie M Sarwal
    Department of Pediatrics, Stanford University, Stanford, California, USA
    Curr Opin Organ Transplant 14:544-51. 2009
  7. ncbi request reprint Chipping into the human genome: novel insights for transplantation
    Minnie M Sarwal
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94304, USA
    Immunol Rev 210:138-55. 2006
  8. ncbi request reprint Designer genes: Filling the gap in transplantation
    Minnie M Sarwal
    Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Transplantation 82:1261-72. 2006
  9. ncbi request reprint Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling
    Minnie Sarwal
    Department of Pediatrics, Stanford University, Stanford, Calif, USA
    N Engl J Med 349:125-38. 2003
  10. doi request reprint Out with the old, in with the new: immunosuppression minimization in children
    Minnie M Sarwal
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94304, USA
    Curr Opin Organ Transplant 13:513-21. 2008

Research Grants

  1. Defining Biomarkers in Pediatric Renal Transplantation
    Minnie Sarwal; Fiscal Year: 2007
  2. Gene and Cytokine Expression in Tolerance and GVHD
    Samuel Strober; Fiscal Year: 2009
  3. Gene and Cytokine Expression in Tolerance and GVHD
    Samuel Strober; Fiscal Year: 2010
  4. Urinary Proteome Monitoring for Transplant Injury
    MINNIE M contact SARWAL; Fiscal Year: 2010

Collaborators

Detail Information

Publications63

  1. ncbi request reprint Immunosuppression minimization in pediatric transplantation
    M Sarwal
    Department of Pediatrics, Stanford University, Palo Alto, CA, USA
    Am J Transplant 7:2227-35. 2007
    ..This article reviews published experience to date with steroid and calcineurin minimization in pediatric renal transplantation and discusses the risks and benefits of these approaches...
  2. pmc In praise of arrays
    Lihua Ying
    Department of Pediatrics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
    Pediatr Nephrol 24:1643-59; quiz 1655, 1659. 2009
    ....
  3. doi request reprint Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury
    Tara K Sigdel
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    J Am Soc Nephrol 23:750-63. 2012
    ..Validation in a larger, prospective transplant cohort may lead to a noninvasive method to predict and monitor for CAI...
  4. doi request reprint The yin and yang of B cells in graft rejection and tolerance
    Valeriya Zarkhin
    Department of Pediatrics, Stanford University, Stanford, CA, USA
    Transplant Rev (Orlando) 24:67-78. 2010
    ..In addition, novel therapies targeting specific B-cell lineages in graft rejection are also discussed, with a view to developing more targeted therapies for graft rejection...
  5. pmc Biomarkers in solid organ transplantation: establishing personalized transplantation medicine
    Silke Roedder
    Department of Pediatrics and Immunology, Stanford University, G306 300 Pasteur Drive, Palo Alto, CA 94304, USA
    Genome Med 3:37. 2011
    ..Several multi-gene expression-based biomarker panels have been identified that accurately predicted graft accommodation in liver transplant recipients and may be developed into a predictive biomarker assay...
  6. pmc Deconvoluting the 'omics' for organ transplantation
    Minnie M Sarwal
    Department of Pediatrics, Stanford University, Stanford, California, USA
    Curr Opin Organ Transplant 14:544-51. 2009
    ..This article reviews some recent applications of the many evolving 'omic technologies to organ transplantation...
  7. ncbi request reprint Chipping into the human genome: novel insights for transplantation
    Minnie M Sarwal
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94304, USA
    Immunol Rev 210:138-55. 2006
    ..Bioinformatics support is integral to the unraveling of the mysteries of the human genome, proteome, and metabolome in disease and in health...
  8. ncbi request reprint Designer genes: Filling the gap in transplantation
    Minnie M Sarwal
    Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Transplantation 82:1261-72. 2006
    ..This article will review the current applications of microarray technology in the field of organ transplantation and discuss the potential impact of this technology on transplantation medicine...
  9. ncbi request reprint Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling
    Minnie Sarwal
    Department of Pediatrics, Stanford University, Stanford, Calif, USA
    N Engl J Med 349:125-38. 2003
    ..We hypothesized that previously unrecognized molecular heterogeneity might underlie some of the variability in the clinical course of acute renal allograft rejection and in its response to treatment...
  10. doi request reprint Out with the old, in with the new: immunosuppression minimization in children
    Minnie M Sarwal
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94304, USA
    Curr Opin Organ Transplant 13:513-21. 2008
    ..To cover the current literature on immunosuppression minimization strategies in pediatric transplantation, with an emphasis on an application of these strategies in renal transplantation...
  11. ncbi request reprint Granulysin expression is a marker for acute rejection and steroid resistance in human renal transplantation
    M M Sarwal
    Department of Pediatrics, Stanford University, Stanford, CA 94305, USA
    Hum Immunol 62:21-31. 2001
    ..Memory CTL abound in steroid resistant grafts and may have a markedly different response to CSA immunotherapy, suggesting a possible mechanism for steroid resistance...
  12. pmc Profiling of autoantibodies in IgA nephropathy, an integrative antibiomics approach
    Tara K Sigdel
    Departments of Pediatrics Nephrology, Stanford University School of Medicine, Stanford, CA 94304, USA
    Clin J Am Soc Nephrol 6:2775-84. 2011
    ..Autoantibody (autoAb) biomarkers to detect and track progression of IgAN are an unmet clinical need. The objective of the study was to identify IgA-specific autoAbs specific to IgAN...
  13. doi request reprint A randomized, prospective trial of rituximab for acute rejection in pediatric renal transplantation
    V Zarkhin
    Department of Pediatrics, Stanford University Medical Center, Stanford, CA, USA
    Am J Transplant 8:2607-17. 2008
    ..There was no change in DSA in either group, independent of rejection resolution. This study reports safety and suggests further investigation of Rituximab as an adjunctive treatment for B-cell-mediated graft rejection...
  14. ncbi request reprint Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in pediatric renal transplantation
    M M Sarwal
    Department of Surgery, Stanford University Medical Center, 703 Welch Road, Suite H-5, Palo Alto, CA 94304, USA
    Transplantation 72:13-21. 2001
    ..This protocol avoids the morbid side effects of steroids without increasing infection, and may play a future critical role in avoiding noncompliance, although optimizing renal function and growth...
  15. pmc Steroid-free immunosuppression since 1999: 129 pediatric renal transplants with sustained graft and patient benefits
    L Li
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Am J Transplant 9:1362-72. 2009
    ....
  16. pmc The proteogenomic path towards biomarker discovery
    Tara K Sigdel
    Department of Pediatrics Nephrology, Stanford University Medical School, Stanford University, Stanford, CA 94305, USA
    Pediatr Transplant 12:737-47. 2008
    ..In this review, we look into the current status and latest developments in the field of biomarker discovery using genomics and proteomics related to organ transplantation, with an emphasis on the evolution of proteomic technologies...
  17. ncbi request reprint A 100% 2-year graft survival can be attained in high-risk 15-kg or smaller infant recipients of kidney allografts
    M T Millan
    Stanford University Medical Center, 750 Welch Rd, Suite 319, Palo Alto, CA 94304, USA
    Arch Surg 135:1063-8; discussion 1068-9. 2000
    ..The principal causes of graft loss have been graft thrombosis, primary nonfunction, technical error, and irreversible acute rejection...
  18. doi request reprint A common peripheral blood gene set for diagnosis of operational tolerance in pediatric and adult liver transplantation
    L Li
    Division of Nephrology, Department of Pediatrics, Stanford University, Palo Alto, CA, USA
    Am J Transplant 12:1218-28. 2012
    ....
  19. doi request reprint Potential influence of tacrolimus and steroid avoidance on early graft function in pediatric renal transplantation
    L Li
    Division of Pediatric Nephrology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Pediatr Transplant 12:701-7. 2008
    ..In patients with slow recovery of early graft function, short-term perioperative steroids may be considered...
  20. pmc Expression of complement components differs between kidney allografts from living and deceased donors
    Maarten Naesens
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Am Soc Nephrol 20:1839-51. 2009
    ..In addition, complement gene expression at the time of implantation was associated with both early and late graft function. These data suggest that complement-modulating therapy may improve graft outcomes in renal transplantation...
  21. ncbi request reprint Continued superior outcomes with modification and lengthened follow-up of a steroid-avoidance pilot with extended daclizumab induction in pediatric renal transplantation
    Minnie M Sarwal
    Department of Pediatrics, Stanford University, Palo Alto, CA 94305, USA
    Transplantation 76:1331-9. 2003
    ..This expanded pilot series discusses immunosuppression dosing modification to further minimize drug toxicity without sacrificing regimen efficacy...
  22. ncbi request reprint Sodium ferric gluconate therapy in renal transplant and renal failure patients
    P D Yorgin
    Department of Pediatrics, Section of Pediatric Nephrology, Stanford University, Lucille Salter Packard Children s Hospital, 703 Welch Road, Suite H5, Stanford, CA 94305, USA
    Pediatr Nephrol 15:171-5. 2000
    ..0 units/kg/week (P = 0.02). Although sodium ferric gluconate appears to be effective and safe at the doses used, multicenter, prospective pharmacokinetic and clinical trials of sodium ferric gluconate should be conducted in children...
  23. ncbi request reprint Visual loss caused by pseudotumor cerebri in an infant on peritoneal dialysis
    A Belson
    Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Pediatr Nephrol 16:216-8. 2001
    ..Physicians responsible for the care of children with renal failure should be aware of the potential for PTC, as the diagnosis should be made as early as possible to prevent permanent visual loss...
  24. pmc Abnormal mitochondrial autophagy in nephropathic cystinosis
    Poonam Sansanwal
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Autophagy 6:971-3. 2010
    ..This study provides ultrastructural and functional evidence of abnormal mitochondrial autophagy in nephropathic cystinosis, which may contribute to renal Fanconi syndrome and progressive renal injury...
  25. doi request reprint Using gene arrays in diagnosis of rejection
    Purvesh Khatri
    Division of Nephrology, Department of Pediatrics, Stanford University, Stanford, California, USA
    Curr Opin Organ Transplant 14:34-9. 2009
    ..This article reviews recent studies in organ transplantation using microarrays and highlights the issues that should be addressed in order to use microarrays in diagnosis of rejection...
  26. ncbi request reprint Gastrointestinal leukocytoclastic vasculitis: an adverse effect of sirolimus
    Suja Nagarajan
    Department of Pediatric Nephrology, Stanford University, Stanford, CA 94305, USA
    Pediatr Transplant 9:97-100. 2005
    ..In light of this report, drug-induced leukocytoclastic vasculitis caused by SRL should be considered in the differential diagnosis of chronic abdominal pain in a patient with organ transplantation...
  27. doi request reprint Combined liver-kidney transplantation in children: indications and outcome
    Scott M Sutherland
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Pediatr Transplant 12:835-46. 2008
    ..While it focuses on the specific primary diseases which impact liver and kidney function simultaneously, it addresses the indications based on concomitant hepatic and renal failure, such as seen in the hepatorenal syndrome, as well...
  28. ncbi request reprint One hundred percent patient and kidney allograft survival with simultaneous liver and kidney transplantation in infants with primary hyperoxaluria: a single-center experience
    Maria T Millan
    Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Transplantation 76:1458-63. 2003
    ..Although others have reported on overall results of transplantation for PH1 covering a wide age spectrum, none has specifically addressed the high-risk infantile form of the disease...
  29. ncbi request reprint A novel, semiquantitative, clinically correlated calcineurin inhibitor toxicity score for renal allograft biopsies
    Neeraja Kambham
    Department of Pathology, Stanford, CA 94305 5324, USA
    Clin J Am Soc Nephrol 2:135-42. 2007
    ..021) and 24 mo (P = 0.03) calculated creatinine clearance. Arteriolar medial hyalinosis seems to be the most important factor contributing to the clinical impact of the CNIT score...
  30. pmc Integrative urinary peptidomics in renal transplantation identifies biomarkers for acute rejection
    Xuefeng B Ling
    Divisions of Biotechnology Core, Department of Pediatrics, Stanford University School of Medicine, Stanford University, Stanford, California, USA
    J Am Soc Nephrol 21:646-53. 2010
    ..98). These data suggest that changes in collagen remodeling characterize AR and that detection of the corresponding proteolytic degradation products in urine provides a noninvasive diagnostic approach...
  31. doi request reprint Insights into novel cellular injury mechanisms by gene expression profiling in nephropathic cystinosis
    Poonam Sansanwal
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    J Inherit Metab Dis 33:775-86. 2010
    ..Further analysis of these genes and pathways may offer critical insights into the clinical spectrum of cystinosis patients and ultimately lead to novel links for targeted therapy...
  32. doi request reprint Protein microarrays identify antibodies to protein kinase Czeta that are associated with a greater risk of allograft loss in pediatric renal transplant recipients
    Scott M Sutherland
    Division of Nephrology, Department of Pediatrics, Stanford University Medical Center, Stanford, CA 94305, USA
    Kidney Int 76:1277-83. 2009
    ..Prospective assessment of serum anti-PKCzeta levels at allograft rejection will be needed to confirm these results...
  33. doi request reprint Extended daclizumab monotherapy for rejection-free survival in non-adherent adolescent recipients of renal allografts
    Abanti Chaudhuri
    Department of Pediatrics and Surgery, Stanford University School of Medicine, CA, USA
    Pediatr Transplant 13:927-32. 2009
    ....
  34. ncbi request reprint Microangiopathy of brain, retina, and inner ear (Susac's syndrome) in an adolescent female presenting as acute disseminated encephalomyelitis
    Jin S Hahn
    Department of Neurology, Stanford University School of Medicine, Stanford, California, USA
    Pediatrics 114:276-81. 2004
    ..The full triad did not develop until 2.5 years after the initial neurologic presentation...
  35. ncbi request reprint Microarrays: a monitoring tool for transplant patients?
    Lauren A Weintraub
    Department of Pediatrics, Stanford University, Stanford, CA 94305, USA
    Transpl Int 19:775-88. 2006
    ..This article will review the current applications of microarray technology in the field of transplantation, and discuss the potential impact of this technology on monitoring of solid organ transplant recipients...
  36. ncbi request reprint Arraying the orchestration of allograft pathology
    Elaine S Mansfield
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Am J Transplant 4:853-62. 2004
    ..This report reviews the current literature of microarray use in transplantation research, compares currently available array platforms, and discusses future application of this technology to clinical organ transplantation...
  37. pmc Steroid-free immunosuppression in pediatric renal transplantation: rationale for and [corrected] outcomes following conversion to steroid based therapy
    Scott Sutherland
    Division of Nephrology, Department of Pediatrics, Stanford University Medical Center, Stanford, CA 94305, USA
    Transplantation 87:1744-8. 2009
    ..Short-term outcomes using steroid-free immunosuppression after renal transplantation have been promising. No studies have examined the incidence of and reasons for steroid-avoidance protocol failures...
  38. pmc Complete steroid avoidance is effective and safe in children with renal transplants: a multicenter randomized trial with three-year follow-up
    M M Sarwal
    California Pacific Medical Center, Sutter Health Care, San Francisco, CA, USA
    Am J Transplant 12:2719-29. 2012
    ..017) and lower cholesterol levels (p = 0.034). In conclusion, complete steroid avoidance is safe and effective in unsensitized children receiving primary kidney transplants...
  39. doi request reprint A peripheral blood diagnostic test for acute rejection in renal transplantation
    L Li
    California Pacific Medical Center, Research Institute, San Francisco, CA, USA
    Am J Transplant 12:2710-8. 2012
    ..The 5-gene set can diagnose AR potentially avoiding the need for invasive renal biopsy. These data support the conduct of a prospective study to validate the clinical predictive utility of this diagnostic tool...
  40. doi request reprint Expression of soluble HLA-G identifies favorable outcomes in liver transplant recipients
    Valeriya Zarkhin
    Division of Nephrology, Department of Pediatrics, Stanford University, Palo Alto, CA 94304, USA
    Transplantation 90:1000-5. 2010
    ..However, the clinical relevance of soluble serum HLA-G molecules in tolerant pediatric and young adult liver transplant patients remains to be studied...
  41. pmc Compartmental localization and clinical relevance of MICA antibodies after renal transplantation
    Li Li
    Department of Pediatrics, Stanford University, Stanford, CA, USA 2 Department of Pathology, Stanford University, Stanford, CA 94304, USA
    Transplantation 89:312-9. 2010
    ..Antibodies (Ab) responses to major and minor human leukocyte antigen loci may impact graft survival after organ transplantation...
  42. pmc Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures
    Li Li
    Department of Pediatrics, Blood and Marrow Transplantation Division, Stanford University, 300 Pasteur Drive, Stanford, CA 94304, USA
    Proc Natl Acad Sci U S A 106:4148-53. 2009
    ..Correlation of the most significant non-HLA antibody responses with transplant health and dysfunction are currently underway...
  43. ncbi request reprint Molecular profiling of anemia in acute renal allograft rejection using DNA microarrays
    Mei Sze Chua
    Department of Pediatrics, Stanford University School of Medicine, CCSR, Stanford CA, USA
    Am J Transplant 3:17-22. 2003
    ..The possible relationship between alterations in the expression of this cluster, reduced renal function, the alloimmune process itself, and other influences on the renal transplant awaits further analysis...
  44. ncbi request reprint Increased expression of cytotoxic effector molecules: different interpretations for steroid-based and steroid-free immunosuppression
    Thomas Satterwhite
    Department of Pediatrics, Stanford University School of Medicine, 269 Campus Drive, CCSR, Stanford, California 94305, USA
    Pediatr Transplant 7:53-8. 2003
    ....
  45. ncbi request reprint Corticosteroid avoidance in pediatric renal transplantation: can it be achieved?
    Jayakumar R Vidhun
    Department of Pediatrics, Stanford University, Palo Alto, California 94305, USA
    Paediatr Drugs 6:273-87. 2004
    ..This protocol may also be applicable to other areas of solid organ transplantation in all age groups...
  46. ncbi request reprint Corticosteroid avoidance in pediatric renal transplantation
    Jayakumar R Vidhun
    Department of Pediatrics, Stanford University, 300 Pasteur Drive, Palo Alto, CA 94305, USA
    Pediatr Nephrol 20:418-26. 2005
    ....
  47. ncbi request reprint Proteinuria in pediatric renal transplant recipients during the first 60 post-transplant days
    Annabelle N Chua
    Department of Pediatrics, Section of Pediatric Nephrology, Stanford University, Stanford, CA, USA
    Pediatr Transplant 10:957-61. 2006
    ..0001) and days post-transplant (-0.531, p < 0.0001). Independent of primary diagnosis, proteinuria persists throughout the first 60 days in most pediatric renal transplant patients, decreasing relative to time post-transplant...
  48. pmc Cell type-specific gene expression differences in complex tissues
    Shai S Shen-Orr
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
    Nat Methods 7:287-9. 2010
    ....
  49. doi request reprint Microarrays: monitoring for transplant tolerance and mechanistic insights
    Valeriya Zarkhin
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94304, USA
    Clin Lab Med 28:385-410, vi. 2008
    ..High throughput microarray technology offers a means to study disease-specific transcriptional changes in tissue biopsy, peripheral blood, and biofluids...
  50. doi request reprint Characterization of intra-graft B cells during renal allograft rejection
    Valeriya Zarkhin
    Department of Pediatrics, Stanford University Medical Center, Stanford, California, USA
    Kidney Int 74:664-73. 2008
    ..These studies suggest that detailed analysis of interstitial cellular infiltrates may allow better use of B-cell lineage specific treatments to improve graft outcomes...
  51. doi request reprint Standardizing resistive indices in healthy pediatric transplant recipients of adult-sized kidneys
    Sepideh Gholami
    Department of Surgery, Stanford University, Stanford, CA 94304, USA
    Pediatr Transplant 14:126-31. 2010
    ....
  52. ncbi request reprint Management of methylmalonic acidaemia by combined liver-kidney transplantation
    S Nagarajan
    Pediatric Nephrology, Stanford University, California 94305 5208, USA
    J Inherit Metab Dis 28:517-24. 2005
    ....
  53. ncbi request reprint The evolution of nonimmune histological injury and its clinical relevance in adult-sized kidney grafts in pediatric recipients
    M Naesens
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Am J Transplant 7:2504-14. 2007
    ....
  54. ncbi request reprint Transplant reno-vascular stenoses associated with early erythropoietin use
    Suja Nagarajan
    Department of Pediatrics Nephrology Stanford University, Palo Alto, CA 94305 5208, USA
    Clin Transplant 21:597-608. 2007
    ..The HTN was secondary to atypical, reno-vascular abnormalities (RVA) of the transplanted vasculature, temporally associated with erythropoietin (EPO) use...
  55. ncbi request reprint Microarrays: new tools for transplantation research
    Mei Sze Chua
    Department of Pediatrics, Stanford University School of Medicine, G320, 300 Pasteur Drive, CA 94305, Stanford, USA
    Pediatr Nephrol 18:319-27. 2003
    ....
  56. ncbi request reprint Interpreting the proteome and peptidome in transplantation
    Tara K Sigdel
    Department of Pediatrics Nephrology, Stanford University Medical School, Stanford University, Stanford, California 94305, USA
    Adv Clin Chem 47:139-69. 2009
    ..In this review, we describe the basic techniques used in proteomic and peptidomic approaches, point out special considerations in using these methods, and discuss their applications in recently published studies in organ transplantation...
  57. ncbi request reprint Noncirrhotic portal hypertension in association with juvenile nephropathic cystinosis: case presentation and review of the literature
    P DiDomenico
    Department of Pediatric Nephrology, Lucile Packard Children s Hospital, Stanford University Medical Center, Palo Alto, California, USA
    J Inherit Metab Dis 27:693-9. 2004
    ..An understanding of the pathophysiology of hepatic dysfunction will be required to manage this potential late complication of the disease...
  58. ncbi request reprint Subclinical cytomegalovirus and Epstein-Barr virus viremia are associated with adverse outcomes in pediatric renal transplantation
    Li Li
    Department of Pediatrics, Stanford University, Palo Alto, CA, USA
    Pediatr Transplant 11:187-95. 2007
    ....
  59. ncbi request reprint Option of pre-emptive nephrectomy and renal transplantation for Bartter's syndrome
    Abanti Chaudhuri
    Department of Pediatrics and Surgery, Stanford University, CA, USA
    Pediatr Transplant 10:266-70. 2006
    ....
  60. pmc Mitochondrial autophagy promotes cellular injury in nephropathic cystinosis
    Poonam Sansanwal
    Department of Pediatrics, G306, 300 Pasteur Drive, Stanford, CA 94304, USA
    J Am Soc Nephrol 21:272-83. 2010
    ..This study provides ultrastructural and functional evidence of abnormal mitophagy in nephropathic cystinosis, which may contribute to the renal Fanconi syndrome and progressive renal injury...
  61. ncbi request reprint Expression profiling of murine double-negative regulatory T cells suggest mechanisms for prolonged cardiac allograft survival
    Boris P L Lee
    Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada
    J Immunol 174:4535-44. 2005
    ..These findings shed light on the mechanisms by which DN Treg cells down-regulate immune responses and prolong cardiac allograft survival...
  62. ncbi request reprint Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling
    Anette Melk
    Division of Nephrology and Transplantation Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Kidney Int 68:2667-79. 2005
    ..The molecular basis of renal aging is not completely understood...
  63. ncbi request reprint Mycophenolate mofetil in pediatric renal transplantation
    Robert Ettenger
    Mattel Children s Hospital, UCLA Medical Center, Los Angeles, CA 90095 1752, USA
    Transplantation 80:S201-10. 2005
    ..Finally, recent studies showing that newer agents used in combination with MMF can further increase efficacy and reduce the risk of adverse events such as posttransplant lymphoproliferative disease are discussed...

Research Grants7

  1. Defining Biomarkers in Pediatric Renal Transplantation
    Minnie Sarwal; Fiscal Year: 2007
    ..The genomic and tissue microarray databases will be made publicly available for the academic community to facilitate future large-scale collaborative studies. ..
  2. Gene and Cytokine Expression in Tolerance and GVHD
    Samuel Strober; Fiscal Year: 2009
    ..In addition to providing information about guidance of drug withdrawal, the studies are designed to provide further insight into the cellular and molecular immune mechanisms of tolerance and GVHD protection. ..
  3. Gene and Cytokine Expression in Tolerance and GVHD
    Samuel Strober; Fiscal Year: 2010
    ..In addition to providing information about guidance of drug withdrawal, the studies are designed to provide further insight into the cellular and molecular immune mechanisms of tolerance and GVHD protection. ..
  4. Urinary Proteome Monitoring for Transplant Injury
    MINNIE M contact SARWAL; Fiscal Year: 2010
    ..We are going to use two most powerful proteomic methods to identify these biomarkers which will be first of its kind in the field of transplantation. ..