T D Sanger

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi Is cerebral palsy a wastebasket diagnosis?
    Terence D Sanger
    J Child Neurol 23:726-8. 2008
  2. doi Hypertonia in childhood secondary dystonia due to cerebral palsy is associated with reflex muscle activation
    Johan van Doornik
    Department of Neurology and Neurological Sciences, Stanford University, Stanford, California 94305 5235, USA
    Mov Disord 24:965-71. 2009
  3. ncbi Arm trajectories in dyskinetic cerebral palsy have increased random variability
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University, CA 94305 5235, USA
    J Child Neurol 21:551-7. 2006
  4. ncbi Botulinum toxin type B improves the speed of reaching in children with cerebral palsy and arm dystonia: an open-label, dose-escalation pilot study
    Terence D Sanger
    Division of Child Neurology and Movement Disorders, Stanford University Medical Center, 300 Pasteur, Room A345, Stanford, CA 94305 5235, USA
    J Child Neurol 22:116-22. 2007
  5. ncbi Bayesian filtering of myoelectric signals
    Terence D Sanger
    Division of Child Neurology and Movement Disorders, Stanford University Medical Center, 300 Pasteur, Room A345, Stanford, CA 94305 5235
    J Neurophysiol 97:1839-45. 2007
  6. ncbi Definition and classification of negative motor signs in childhood
    Terence D Sanger
    Division of Child Neurology and Movement Disorders, Stanford University Medical Center, 300 Pasteur, Room A345, Stanford, CA 94305 5235, USA
    Pediatrics 118:2159-67. 2006
  7. ncbi Prospective open-label clinical trial of trihexyphenidyl in children with secondary dystonia due to cerebral palsy
    Terence D Sanger
    Stanford University, Stanford, California, USA
    J Child Neurol 22:530-7. 2007
  8. ncbi Optimizing assisted communication devices for Children with motor impairments using a model of information rate and channel capacity
    Terence D Sanger
    Stanford University Department of Neurology and Neurological Sciences, Division of Child Neurology, Stanford, CA 94305, USA
    IEEE Trans Neural Syst Rehabil Eng 15:458-68. 2007
  9. ncbi Reaching movements in childhood dystonia contain signal-dependent noise
    Terence D Sanger
    Department of Neurology, Division of Child Neurology and Movement Disorders, Stanford University, Stanford, CA, USA
    J Child Neurol 20:489-96. 2005
  10. ncbi Toward a definition of childhood dystonia
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, California 94305 5235, USA
    Curr Opin Pediatr 16:623-7. 2004

Research Grants

  1. Arm Kinematics in Hyperkinetic Cerebral Palsy
    Terence Sanger; Fiscal Year: 2005
  2. Childhood Motor Impairment and Assisted Communication
    Terence Sanger; Fiscal Year: 2004
  3. NIH Task Force on Childhood Motor Disorders
    Terence Sanger; Fiscal Year: 2006
  4. Neural control of abnormal movement
    Terence Sanger; Fiscal Year: 2006
  5. Taskforce on Childhood Motor Disorders
    Terence Sanger; Fiscal Year: 2007

Detail Information

Publications27

  1. ncbi Is cerebral palsy a wastebasket diagnosis?
    Terence D Sanger
    J Child Neurol 23:726-8. 2008
  2. doi Hypertonia in childhood secondary dystonia due to cerebral palsy is associated with reflex muscle activation
    Johan van Doornik
    Department of Neurology and Neurological Sciences, Stanford University, Stanford, California 94305 5235, USA
    Mov Disord 24:965-71. 2009
    ....
  3. ncbi Arm trajectories in dyskinetic cerebral palsy have increased random variability
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University, CA 94305 5235, USA
    J Child Neurol 21:551-7. 2006
    ..This result shows that there is increased movement variability, and it is consistent with the hypothesis that inadequate removal of noisy signals could be a cause of the movement disorder in dyskinetic cerebral palsy...
  4. ncbi Botulinum toxin type B improves the speed of reaching in children with cerebral palsy and arm dystonia: an open-label, dose-escalation pilot study
    Terence D Sanger
    Division of Child Neurology and Movement Disorders, Stanford University Medical Center, 300 Pasteur, Room A345, Stanford, CA 94305 5235, USA
    J Child Neurol 22:116-22. 2007
    ..These results support the use of botulinum toxin type B as a safe and effective treatment for upper extremity dystonia in children with cerebral palsy. Larger controlled trials are needed to confirm these results...
  5. ncbi Bayesian filtering of myoelectric signals
    Terence D Sanger
    Division of Child Neurology and Movement Disorders, Stanford University Medical Center, 300 Pasteur, Room A345, Stanford, CA 94305 5235
    J Neurophysiol 97:1839-45. 2007
    ..Use of the nonlinear filter significantly reduces noise compared with current algorithms, and it may therefore permit more effective use of the EMG signal for prosthetic control, biofeedback, and neurophysiology research...
  6. ncbi Definition and classification of negative motor signs in childhood
    Terence D Sanger
    Division of Child Neurology and Movement Disorders, Stanford University Medical Center, 300 Pasteur, Room A345, Stanford, CA 94305 5235, USA
    Pediatrics 118:2159-67. 2006
    ....
  7. ncbi Prospective open-label clinical trial of trihexyphenidyl in children with secondary dystonia due to cerebral palsy
    Terence D Sanger
    Stanford University, Stanford, California, USA
    J Child Neurol 22:530-7. 2007
    ..A larger, randomized prospective trial stratified by the presence or absence of hyperkinetic movements is needed to confirm these results...
  8. ncbi Optimizing assisted communication devices for Children with motor impairments using a model of information rate and channel capacity
    Terence D Sanger
    Stanford University Department of Neurology and Neurological Sciences, Division of Child Neurology, Stanford, CA 94305, USA
    IEEE Trans Neural Syst Rehabil Eng 15:458-68. 2007
    ..Optimization of the information rate may be useful for programming assisted communication devices...
  9. ncbi Reaching movements in childhood dystonia contain signal-dependent noise
    Terence D Sanger
    Department of Neurology, Division of Child Neurology and Movement Disorders, Stanford University, Stanford, CA, USA
    J Child Neurol 20:489-96. 2005
    ..This finding is consistent with the hypothesis of increased signal-dependent noise in children with dystonia, and we present a simple computational model that provides a possible explanation for the origin of this noise...
  10. ncbi Toward a definition of childhood dystonia
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, California 94305 5235, USA
    Curr Opin Pediatr 16:623-7. 2004
    ..The purpose of this review is to summarize recent progress toward providing a consistent, sensitive, specific, and useful definition of dystonia as it presents in childhood...
  11. ncbi Failure of motor learning for large initial errors
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305 5235, USA
    Neural Comput 16:1873-86. 2004
    ..We suggest that this may provide a model for the lack of improvement in human skills that can occur despite repeated practice of a complex task...
  12. ncbi Severe resting clonus caused by thyrotoxicosis in a 16-year-old girl with hereditary spastic paraparesis: a case report
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, California 94305 5235, USA
    Mov Disord 19:712-3. 2004
    ..It also demonstrates the importance of investigating for common systemic diseases as a cause of movement disorders even in children with underlying known genetic disorders...
  13. pmc Childhood onset generalised dystonia can be modelled by increased gain in the indirect basal ganglia pathway
    T D Sanger
    Department of Neurology and Neurosciences, Stanford University Medical Center, Stanford, California 95305 5235, USA
    J Neurol Neurosurg Psychiatry 74:1509-15. 2003
    ....
  14. ncbi Pathophysiology of pediatric movement disorders
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Pediatric Movement Disorders Clinic, Stanford University Medical Center, Stanford, CA 94305 5235, USA
    J Child Neurol 18:S9-24. 2003
    ....
  15. ncbi Pediatric movement disorders
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, CA 94305, USA
    Curr Opin Neurol 16:529-35. 2003
    ..The purpose of this review is to summarize recent advances in diagnosis and treatment for childhood movement disorders...
  16. ncbi Neural population codes
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Pediatric Movement Disorders Clinic, Stanford University Medical Center, 300 Pasteur Drive, A345, Stanford, CA 94305 5235, USA
    Curr Opin Neurobiol 13:238-49. 2003
    ..We show that for population codes based on neurons that have a Poisson distribution of spike probabilities, the behavior and computational properties of the code can be understood in terms of the tuning properties of individual cells...
  17. ncbi Classification and definition of disorders causing hypertonia in childhood
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, California 94305 5235, USA
    Pediatrics 111:e89-97. 2003
    ..The definitions presented here are designed to allow differentiation of clinical features even when more than 1 is present simultaneously...
  18. pmc Use of surface electromyography (EMG) in the diagnosis of childhood hypertonia: a pilot study
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University, Stanford, California, USA
    J Child Neurol 23:644-8. 2008
    ..These results support the importance of further testing of surface EMG as an adjunct to the clinical examination of childhood hypertonia...
  19. ncbi Abnormalities of tactile sensory function in children with dystonic and diplegic cerebral palsy
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305 5235, USA
    J Child Neurol 22:289-93. 2007
    ..These results are the first to test the spatial discrimination threshold using Johnson, Van Boven, Phillips domes in children with cerebral palsy...
  20. doi Oral baclofen increases maximal voluntary neuromuscular activation of ankle plantar flexors in children with spasticity due to cerebral palsy
    Johan van Doornik
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, CA 94305 5235, USA
    J Child Neurol 23:635-9. 2008
    ..Mean maximal plantar flexion torque did not change. We conjecture that antispasticity agents could facilitate strength training by increasing the ability to voluntarily activate muscle...
  21. doi Force variability during isometric biceps contraction in children with secondary dystonia due to cerebral palsy
    Way Tong Virginia Chu
    Department of Bioengineering, Stanford University, California, USA
    Mov Disord 24:1299-305. 2009
    ..These results contribute to a better understanding of movement variability in childhood dystonia and have potential use in therapeutic interventions designed to increase force production reliability...
  22. ncbi Abnormal coupling of knee and hip moments during maximal exertions in persons with cerebral palsy
    Darryl D Thelen
    Biomechanical Engineering Division, Mechanical Engineering Department, Stanford University, California, USA
    Muscle Nerve 27:486-93. 2003
    ..05). The patterns of joint moments generated by CP subjects are consistent with an extension synergy and may underlie the coupled motion patterns of the lower extremity in such persons...
  23. ncbi Does dystonia always include co-contraction? A study of unconstrained reaching in children with primary and secondary dystonia
    Nicole Malfait
    Department of Neurology and Neurological Sciences, Stanford University, 300 Pasteur Dr, A347, Stanford, CA 94305 5235, USA
    Exp Brain Res 176:206-16. 2007
    ....
  24. ncbi A probabilistic algorithm for estimating the intention of computer users with movement disorders
    Adam D Grossman
    Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:3605-8. 2007
    ..We also implement the algorithm as part of text-entry software and perform a preliminary case study on a patient with dystonia, using a joystick as a text input device...
  25. ncbi Decoding neural spike trains: calculating the probability that a spike train and an external signal are related
    Terence D Sanger
    Department of Child Neurology, Stanford University Medical Center, 300 Pasteur Drive, MS 5235, Stanford, CA 94305, USA
    J Neurophysiol 87:1659-63. 2002
    ..The performance of the new algorithm is compared with the performance of correlation methods on simulated data...
  26. ncbi Nonlinear sensory cortex response to simultaneous tactile stimuli in writer's cramp
    Terence D Sanger
    Department of Child Neurology, Stanford University Medical Center, Stanford, California USA
    Mov Disord 17:105-11. 2002
    ..Results indicate a nonlinear interaction between the sensory cortical response to individual finger stimulation in writer's cramp. This altered interaction may contribute to the motor abnormalities...
  27. ncbi Poor penmanship in children correlates with abnormal rhythmic tapping: a broad functional temporal impairment
    Hilla Ben-Pazi
    Department of Child Neurology, Stanford Medical Center, Stanford, California, USA
    J Child Neurol 22:543-9. 2007
    ..Evaluation of dysfunctional motor performance should include temporal aspects, and further studies are needed to better delineate and address treatment of "dysrhythmia."..

Research Grants7

  1. Arm Kinematics in Hyperkinetic Cerebral Palsy
    Terence Sanger; Fiscal Year: 2005
    ..Hlatky will guide the design and implementation of clinical trials and outcome measure validation. The proposal includes coursework in cellular and molecular neurobiology and in the design of clinical research studies. ..
  2. Childhood Motor Impairment and Assisted Communication
    Terence Sanger; Fiscal Year: 2004
    ....
  3. NIH Task Force on Childhood Motor Disorders
    Terence Sanger; Fiscal Year: 2006
    ..The ultimate objective is to improve the functional abilities and societal participation of children with motor disorders. ..
  4. Neural control of abnormal movement
    Terence Sanger; Fiscal Year: 2006
    ....
  5. Taskforce on Childhood Motor Disorders
    Terence Sanger; Fiscal Year: 2007
    ..The result will be definitions and recommendations that will improve the effectiveness and success of clinical trials for children with disorders of movement. ..