Research Topics
| Shelley R SalpeterSummaryAffiliation: Stanford University Country: USA Publications
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Publications
An update on the safety of long-acting beta-agonists in asthma patients using inhaled corticosteroidsShelley R Salpeter
Department of Medicine, Stanford University School of Medicine, California, USA
Expert Opin Drug Saf 9:407-19. 2010..Until recently, it was unclear whether concomitant inhaled corticosteroids (ICSs) could eliminate this risk...
Systematic review of noncancer presentations with a median survival of 6 months or lessShelley R Salpeter
Stanford University School of Medicine, CA, USA
Am J Med 125:512.e1-6. 2012..We report on clinical indicators of 6-month mortality in advanced noncancer illnesses and the effect of treatment on survival...
Systematic review of cancer presentations with a median survival of six months or lessShelley R Salpeter
Sutter Care at Home, San Mateo, CA, USA
J Palliat Med 15:175-85. 2012..To report cancer presentations with a median survival of 6 months or less and the effect of treatment on survival...
Meta-analysis: anticholinergics, but not beta-agonists, reduce severe exacerbations and respiratory mortality in COPDShelley R Salpeter
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
J Gen Intern Med 21:1011-9. 2006..Anticholinergics and beta2-agonists have generally been considered equivalent choices for bronchodilation in chronic obstructive pulmonary disease (COPD)...
Systematic review of clinical outcomes in chronic obstructive pulmonary disease: beta-agonist use compared with anticholinergics and inhaled corticosteroidsShelley R Salpeter
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
Clin Rev Allergy Immunol 31:219-30. 2006..beta-Agonists increase respiratory deaths in COPD, possibly as a result of poorer disease control...
Should we avoid beta-agonists for moderate and severe chronic obstructive pulmonary disease? YESShelley R Salpeter
Department of Medicine at Stanford University School of Medicine, Calif, USA
Can Fam Physician 53:1290-7. 2007
Bronchodilators in COPD: impact of beta-agonists and anticholinergics on severe exacerbations and mortalityShelley R Salpeter
Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
Int J Chron Obstruct Pulmon Dis 2:11-8. 2007..These results indicate that anticholinergics should be the bronchodilator of choice in COPD, while beta-agonists may be associated with poorer disease control...
Meta-analysis: metformin treatment in persons at risk for diabetes mellitusShelley R Salpeter
Santa Clara Valley Medical Center, San Jose, CA 95128, USA
Am J Med 121:149-157.e2. 2008..We performed a meta-analysis of randomized controlled trials to assess the effect of metformin on metabolic parameters and the incidence of new-onset diabetes in persons at risk for diabetes...
The cost-effectiveness of hormone therapy in younger and older postmenopausal womenShelley R Salpeter
Department of Medicine, Santa Clara Valley Medical Center, San Jose, Calif 95128, USA
Am J Med 122:42-52.e2. 2009..To evaluate the health and economic outcomes of hormone therapy in younger and older postmenopausal women...
Do inhaled anticholinergics increase or decrease the risk of major cardiovascular events?: a synthesis of the available evidenceShelley R Salpeter
Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
Drugs 69:2025-33. 2009..It is possible that the reduction in respiratory morbidity could improve functional status and reduce adverse cardiac outcomes over time. Further studies are needed to address this important issue...
Bayesian meta-analysis of hormone therapy and mortality in younger postmenopausal womenShelley R Salpeter
Santa Clara Valley Medical Center, 751 S Bascom Ave, San Jose, CA 95128, USA
Am J Med 122:1016-1022.e1. 2009..This analysis synthesizes evidence from different sources, taking into account varying views on the issue...
Long-acting beta-agonists with and without inhaled corticosteroids and catastrophic asthma eventsShelley R Salpeter
Stanford University School of Medicine, Stanford, CA, USA
Am J Med 123:322-8.e2. 2010..We pooled data on long-acting beta-agonists with variable and concomitant inhaled corticosteroids to evaluate the risk for catastrophic asthma events...
Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal womenS R Salpeter
Stanford University School of Medicine, Stanford, CA, USA
Diabetes Obes Metab 8:538-54. 2006..To quantify the effects of hormone-replacement therapy (HRT) on components of the metabolic syndrome in postmenopausal women...
Meta-analysis: cardiovascular events associated with nonsteroidal anti-inflammatory drugsShelley R Salpeter
Stanford University School of Medicine, Stanford, California, USA
Am J Med 119:552-9. 2006..We performed a meta-analysis of randomized controlled trials to assess the effect of nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) on cardiovascular events in trials of joint disease and Alzheimer's disease...
Cardioselective beta-blockers for chronic obstructive pulmonary disease: a meta-analysisS R Salpeter
Stanford University School of Medicine, CA, USA
Respir Med 97:1094-101. 2003..Given their demonstrated benefit in conditions such as heart failure, coronary artery disease and hypertension, cardioselective beta-blockers should be considered for patients with COPD...
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus: systematic review and meta-analysisShelley R Salpeter
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
Arch Intern Med 163:2594-602. 2003..The true incidence of fatal and nonfatal lactic acidosis associated with metformin use is not known...
Cardiovascular safety of beta(2)-adrenoceptor agonist use in patients with obstructive airway disease: a systematic reviewShelley R Salpeter
Stanford University School of Medicine, Stanford, California, USA
Drugs Aging 21:405-14. 2004....
Cardiovascular effects of beta-agonists in patients with asthma and COPD: a meta-analysisShelley R Salpeter
Santa Clara Valley Medical Center, San Jose, CA, USA
Chest 125:2309-21. 2004..beta(2)-Agonist use in patients with obstructive airway disease has been associated with an increased risk for myocardial infarction, congestive heart failure, cardiac arrest, and acute cardiac death...
Mortality associated with hormone replacement therapy in younger and older women: a meta-analysisShelley R Salpeter
Department of Medicine, Santa Clara Valley Medical Center, San Jose, CA 95128, USA
J Gen Intern Med 19:791-804. 2004..To assess mortality associated with hormone replacement in younger and older postmenopausal women...
Brief report: Coronary heart disease events associated with hormone therapy in younger and older women. A meta-analysisShelley R Salpeter
Department of Medicine, Santa Clara Valley Medical Center, San Jose, CA 95128, USA
J Gen Intern Med 21:363-6. 2006..To assess the effect of hormone therapy (HT) on coronary heart disease (CHD) events in younger and older postmenopausal women...
Meta-analysis: effect of long-acting beta-agonists on severe asthma exacerbations and asthma-related deathsShelley R Salpeter
Santa Clara Valley Medical Center, San Jose, California 95128, USA
Ann Intern Med 144:904-12. 2006..Long-acting beta-agonists may increase the risk for fatal and nonfatal asthma exacerbations...
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitusShelley R Salpeter
Medicine, Stanford University, and Santa Clara Valley Medical Center, 2400 Moorpark Ave, Suite 118, San Jose, CA, USA, 95128
Cochrane Database Syst Rev 4:CD002967. 2010....
Cardioselective beta-blockers in patients with reactive airway disease: a meta-analysisShelley R Salpeter
Stanford University School of Medicine, Palo Alto, California, USA
Ann Intern Med 137:715-25. 2002..To assess the effect of cardioselective beta-blockers on respiratory function of patients with reactive airway disease...
Meta-analysis: respiratory tolerance to regular beta2-agonist use in patients with asthmaShelley R Salpeter
Stanford University School of Medicine, Stanford, USA
Ann Intern Med 140:802-13. 2004..CONCLUSION: Regular beta2-agonist use for at least 1 week in patients with asthma results in tolerance to the drug's bronchodilator and nonbronchodilator effects and may be associated with poorer disease control compared with placebo...
Two cardiovascular risk factors in one? Homocysteine and its relation to glomerular filtration rate. A meta-analysis of 41 studies with 27,000 participantsJan T Kielstein
Department of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305 5406, USA
Kidney Blood Press Res 31:259-67. 2008..We performed a meta-analysis of studies that report correlations between glomerular filtration rate (GFR) and homocysteine plasma levels...
Effect of KRAS mutational status in advanced colorectal cancer on the outcomes of anti-epidermal growth factor receptor monoclonal antibody therapy: a systematic review and meta-analysisAlbert Y Lin
Department of Medicine, Santa Clara Valley Medical Center, San Jose, CA 95128, USA
Clin Colorectal Cancer 10:63-9. 2011..Emerging data suggest that somatic KRAS mutation in advanced colorectal cancer is a strong predictor of non-response to anti-epidermal growth factor receptor antibody (anti-EGFR) therapy...
Gene expression profiles as predictors of poor outcomes in stage II colorectal cancer: A systematic review and meta-analysisAn Ting T Lu
Santa Clara Valley Medical Center, San Jose, CA 95128, USA
Clin Colorectal Cancer 8:207-14. 2009..We performed a systematic review and meta-analysis of gene expression profiles (GEPs) to assess their utility for risk stratification and prediction of poor outcomes in stage II CRC...
Beta-blocker use in patients with congestive heart failure and concomitant obstructive airway disease: moving from myth to evidence-based practiceThomas M Ormiston
Stanford University School of Medicine and Santa Clara Valley Medical Center, San Jose, CA 95128, USA
Heart Fail Monit 4:45-54. 2003..This article will review the evidence concerning the safety of beta-blocker use in patients with CHF and concomitant obstructive lung disease, with specific attention to tracking the transition from myth to evidence- based practice...
Screening and treatment of latent tuberculosis among healthcare workers at low, moderate, and high risk for tuberculosis exposure: a cost-effectiveness analysisShelley R Salpeter
Santa Clara Valley Medical Center, San Jose, USA
Infect Control Hosp Epidemiol 25:1056-61. 2004..Each institution could use its own skin test surveillance data to create an optimum screening program for its employees. However, for most HCWs, a 1-year screening interval would be a cost-effective and safe choice...
Systematic review: the effects of growth hormone on athletic performanceHau Liu
Santa Clara Valley Medical Center, San Jose, California 95128, USA
Ann Intern Med 148:747-58. 2008..Human growth hormone is reportedly used to enhance athletic performance, although its safety and efficacy for this purpose are poorly understood...
Symmetric dimethylarginine (SDMA) as endogenous marker of renal function--a meta-analysisJan T Kielstein
Division of Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5406, USA
Nephrol Dial Transplant 21:2446-51. 2006..The purpose of this analysis was to identify the role of symmetric dimethylarginine (SDMA), the structural isomer of the cardiovascular risk marker asymmetric dimethylarginine, as an endogenous marker of renal function...
Rebuttal: should we avoid beta-agonists for moderate and severe chronic obstructive pulmonary disease? YesShelley R Salpeter
Can Fam Physician 53:1429-30, 1432-3. 2007
