Keyan Salari

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc DR-Integrator: a new analytic tool for integrating DNA copy number and gene expression data
    Keyan Salari
    Department of Pathology, Stanford University, Stanford, CA, USA
    Bioinformatics 26:414-6. 2010
  2. pmc A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer
    Sameer Malhotra
    Department of Urology, Stanford University, Stanford, California, United States of America
    PLoS ONE 6:e20293. 2011
  3. pmc Genomic instability in breast cancer: pathogenesis and clinical implications
    Kevin A Kwei
    Department of Pathology, Stanford University School of Medicine, CCSR 3245A, 269 Campus Drive, Stanford, CA 94305 5176, USA
    Mol Oncol 4:255-66. 2010
  4. pmc Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery
    Jessica Kao
    Department of Pathology, Stanford University, Stanford, CA, USA
    PLoS ONE 4:e6146. 2009
  5. pmc Integrative bioinformatics links HNF1B with clear cell carcinoma and tumor-associated thrombosis
    Justin Cuff
    Department of Pathology, Stanford University, Stanford, California, United States of America
    PLoS ONE 8:e74562. 2013
  6. doi request reprint hCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen signaling signature
    Jacques Lapointe
    Department of Pathology, Stanford University, Stanford, CA 94305 51, USA
    Am J Surg Pathol 32:205-9. 2008
  7. pmc CDX2 is an amplified lineage-survival oncogene in colorectal cancer
    Keyan Salari
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 109:E3196-205. 2012
  8. pmc Molecular inversion probe analysis of gene copy alterations reveals distinct categories of colorectal carcinoma
    Hanlee Ji
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5151, USA
    Cancer Res 66:7910-9. 2006
  9. doi request reprint Integration of diverse microarray data types
    Keyan Salari
    Departments of Pathology and Genetics, Stanford University, Stanford, CA, USA
    Methods Mol Biol 556:205-16. 2009
  10. pmc Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer
    Kevin A Kwei
    Department of Pathology, Stanford University, Stanford, California, United States of America
    PLoS Genet 4:e1000081. 2008

Collaborators

Detail Information

Publications13

  1. pmc DR-Integrator: a new analytic tool for integrating DNA copy number and gene expression data
    Keyan Salari
    Department of Pathology, Stanford University, Stanford, CA, USA
    Bioinformatics 26:414-6. 2010
    ....
  2. pmc A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer
    Sameer Malhotra
    Department of Urology, Stanford University, Stanford, California, United States of America
    PLoS ONE 6:e20293. 2011
    ..Our findings highlight the potential value of a multi-gene signature-based diagnostic, and define a tri-marker proliferation index with possible utility for improved prognostication and treatment stratification in prostate cancer...
  3. pmc Genomic instability in breast cancer: pathogenesis and clinical implications
    Kevin A Kwei
    Department of Pathology, Stanford University School of Medicine, CCSR 3245A, 269 Campus Drive, Stanford, CA 94305 5176, USA
    Mol Oncol 4:255-66. 2010
    ..Future studies should clarify the pathogenesis of breast cancers with amplifier and complex-pattern genomes, and will likely identify new therapeutic opportunities...
  4. pmc Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery
    Jessica Kao
    Department of Pathology, Stanford University, Stanford, CA, USA
    PLoS ONE 4:e6146. 2009
    ..Here, we studied a collection of breast cancer cell lines to catalog molecular profiles and to assess their relation to breast cancer subtypes...
  5. pmc Integrative bioinformatics links HNF1B with clear cell carcinoma and tumor-associated thrombosis
    Justin Cuff
    Department of Pathology, Stanford University, Stanford, California, United States of America
    PLoS ONE 8:e74562. 2013
    ..Our findings also implicate a novel mechanism of tumor-associated thrombosis (a major cause of cancer mortality), based on the direct production of clotting factors by cancer cells...
  6. doi request reprint hCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen signaling signature
    Jacques Lapointe
    Department of Pathology, Stanford University, Stanford, CA 94305 51, USA
    Am J Surg Pathol 32:205-9. 2008
    ..019). Our findings identify hCAP-D3 as a new biomarker for subtype-1 tumors that improves prognostication, and reveal androgen signaling as an important biologic feature of this potentially clinically favorable molecular subtype...
  7. pmc CDX2 is an amplified lineage-survival oncogene in colorectal cancer
    Keyan Salari
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 109:E3196-205. 2012
    ..Our findings challenge a prevailing view that CDX2 is a tumor suppressor in colorectal cancer and uncover an additional piece in the multistep model of colorectal tumorigenesis...
  8. pmc Molecular inversion probe analysis of gene copy alterations reveals distinct categories of colorectal carcinoma
    Hanlee Ji
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5151, USA
    Cancer Res 66:7910-9. 2006
    ..This finding has potential clinical ramifications given the application of 18q loss of heterozygosity events as a potential indicator for adjuvant treatment in stage II colorectal carcinoma...
  9. doi request reprint Integration of diverse microarray data types
    Keyan Salari
    Departments of Pathology and Genetics, Stanford University, Stanford, CA, USA
    Methods Mol Biol 556:205-16. 2009
    ..This chapter will outline general approaches to microarray data integration and provide an introduction to DR-Integrator, a broadly useful analysis tool for the integration of DNA copy number and gene-expression microarray data...
  10. pmc Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer
    Kevin A Kwei
    Department of Pathology, Stanford University, Stanford, California, United States of America
    PLoS Genet 4:e1000081. 2008
    ....
  11. pmc Integrative genomic and functional profiling of the pancreatic cancer genome
    A Hunter Shain
    Departments of Pathology, Stanford University School of Medicine, 269 Campus Drive, CCSR 3245A, Stanford, CA 94305 5176, USA
    BMC Genomics 14:624. 2013
    ..To address this challenge, here we have devised a highly-parallel RNA interference-based functional screen to evaluate many genomically-nominated candidate pancreatic cancer genes simultaneously...
  12. ncbi request reprint Genomic profiling reveals alternative genetic pathways of prostate tumorigenesis
    Jacques Lapointe
    Department of Pathology, Stanford University, Stanford, California, USA
    Cancer Res 67:8504-10. 2007
    ..The resultant molecular genetic subtypes provide a new framework for investigating prostate cancer biology and explain in part the clinical heterogeneity of the disease...