Bita Sahaf

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Lymphocyte surface thiol levels
    Bita Sahaf
    Department of Genetics, Stanford School of Medicine, Stanford, CA 94305 5318, USA
    Proc Natl Acad Sci U S A 100:4001-5. 2003
  2. ncbi request reprint The extracellular microenvironment plays a key role in regulating the redox status of cell surface proteins in HIV-infected subjects
    Bita Sahaf
    Herzenberg Laboratory, Department of Genetics, Beckman Center, B 007 Stanford University School of Medicine Stanford, CA 94304 5318, USA
    Arch Biochem Biophys 434:26-32. 2005
  3. ncbi request reprint Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements
    Scott D Boyd
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    J Immunol 184:6986-92. 2010
  4. pmc H-Y antigen-binding B cells develop in male recipients of female hematopoietic cells and associate with chronic graft vs. host disease
    Bita Sahaf
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 110:3005-10. 2013
  5. pmc High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment
    Aaron C Logan
    Divisions of Blood and Marrow Transplantation and Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 108:21194-9. 2011
  6. pmc Culturing of human peripheral blood cells reveals unsuspected lymphocyte responses relevant to HIV disease
    Bita Sahaf
    Department of Genetics and Department of Pediatrics, Division of Stem Cell Transplantation, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 105:5111-6. 2008
  7. pmc Modern flow cytometry: a practical approach
    James W Tung
    Department of Genetics, School of Medicine, Stanford University, Stanford, CA 94305, USA
    Clin Lab Med 27:453-68, v. 2007
  8. ncbi request reprint The history and future of the fluorescence activated cell sorter and flow cytometry: a view from Stanford
    Leonard A Herzenberg
    Stanford University, Department of Genetics, Stanford, CA 94305, USA
    Clin Chem 48:1819-27. 2002
  9. pmc Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence
    Sally Arai
    Division of Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, CA 94305, USA
    Blood 119:6145-54. 2012
  10. ncbi request reprint Clinical impact of H-Y alloimmunity
    Rakesh Popli
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA
    Immunol Res 58:249-58. 2014

Collaborators

Detail Information

Publications13

  1. pmc Lymphocyte surface thiol levels
    Bita Sahaf
    Department of Genetics, Stanford School of Medicine, Stanford, CA 94305 5318, USA
    Proc Natl Acad Sci U S A 100:4001-5. 2003
    ..Collectively, our findings indicate that local environment plays a greater role in determining the redox status of cell surface molecules than the internal redox status of the cells...
  2. ncbi request reprint The extracellular microenvironment plays a key role in regulating the redox status of cell surface proteins in HIV-infected subjects
    Bita Sahaf
    Herzenberg Laboratory, Department of Genetics, Beckman Center, B 007 Stanford University School of Medicine Stanford, CA 94304 5318, USA
    Arch Biochem Biophys 434:26-32. 2005
    ....
  3. ncbi request reprint Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements
    Scott D Boyd
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    J Immunol 184:6986-92. 2010
    ..These deletions significantly alter the potential expressed IGH repertoire, and possibly immune function, in this individual...
  4. pmc H-Y antigen-binding B cells develop in male recipients of female hematopoietic cells and associate with chronic graft vs. host disease
    Bita Sahaf
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 110:3005-10. 2013
    ..Our study suggests that detection of anti-DBY-2 B cells may predict cGVHD and that this prediction may have clinical utility. Validation of this hypothesis will require larger prospective studies...
  5. pmc High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment
    Aaron C Logan
    Divisions of Blood and Marrow Transplantation and Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 108:21194-9. 2011
    ....
  6. pmc Culturing of human peripheral blood cells reveals unsuspected lymphocyte responses relevant to HIV disease
    Bita Sahaf
    Department of Genetics and Department of Pediatrics, Division of Stem Cell Transplantation, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 105:5111-6. 2008
    ..These findings strongly recommend culturing primary cells at physiological oxygen levels. In addition, they suggest HIV-Tat as a key regulator of HIV disease progression...
  7. pmc Modern flow cytometry: a practical approach
    James W Tung
    Department of Genetics, School of Medicine, Stanford University, Stanford, CA 94305, USA
    Clin Lab Med 27:453-68, v. 2007
    ..FACS technology development and the emergence of new software support for this technology are cooperating in this effort...
  8. ncbi request reprint The history and future of the fluorescence activated cell sorter and flow cytometry: a view from Stanford
    Leonard A Herzenberg
    Stanford University, Department of Genetics, Stanford, CA 94305, USA
    Clin Chem 48:1819-27. 2002
    ..Thus, key functions can be studied in various subsets of cells without the need for prior sorting...
  9. pmc Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence
    Sally Arai
    Division of Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, CA 94305, USA
    Blood 119:6145-54. 2012
    ..01). Overall survival and freedom from progression at 4 years for chronic lymphocytic leukemia patients were 73% and 47%, respectively; for mantle-cell lymphoma patients, they were 69% and 53%, respectively...
  10. ncbi request reprint Clinical impact of H-Y alloimmunity
    Rakesh Popli
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA
    Immunol Res 58:249-58. 2014
    ..Our development of more sensitive antibody detection and next-generation DNA sequencing promises to further advance our understanding and better predict the clinical consequences of alloimmunity...
  11. doi request reprint Recombinant antigen microarrays for serum/plasma antibody detection
    Persis P Wadia
    Department of Medicine, Blood and Marrow Transplantation Division, Stanford University, Stanford, CA, USA
    Methods Mol Biol 723:81-104. 2011
    ..This chapter discusses our recombinant antigen microarray methods to measure these clinically relevant allo-antibodies...
  12. pmc Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing
    Scott D Boyd
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Sci Transl Med 1:12ra23. 2009
    ....
  13. ncbi request reprint Enzyme-linked immunospot assay for detection of thioredoxin and thioredoxin reductase secretion from cells
    Bita Sahaf
    Herzenberg Laboratory, Beckman Center, Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA
    Methods Enzymol 353:22-35. 2002
    ..We concluded that the ELISpot assay is a useful method for detection of single cells secreting the redox-active proteins Trx and TrxR after oxidative stress exposure...