RICHARD REIMER

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint SLC17: a functionally diverse family of organic anion transporters
    Richard J Reimer
    Neurogenetics Division Department of Neurology and Neurological Sciences, Stanford University School of Medicine, P211 MSLS, 1201 Welch Road, Stanford, CA 94305, USA
    Mol Aspects Med 34:350-9. 2013
  2. ncbi request reprint Organic anion transport is the primary function of the SLC17/type I phosphate transporter family
    Richard J Reimer
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, CA 94305, Stanford, USA
    Pflugers Arch 447:629-35. 2004
  3. ncbi request reprint Varied mechanisms underlie the free sialic acid storage disorders
    Christopher C Wreden
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    J Biol Chem 280:1408-16. 2005
  4. pmc Biochemical and genetic analysis of ANK in arthritis and bone disease
    Kyle A Gurley
    Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Hum Genet 79:1017-29. 2006
  5. pmc Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport
    Kimberly A Zaia
    Department of Neurology and Neurological Sciences and Neuroscience Graduate Program, Stanford University, Stanford, California 94305, USA
    J Biol Chem 284:8439-48. 2009
  6. pmc The lysosomal sialic acid transporter sialin is required for normal CNS myelination
    Laura M Prolo
    Department of Neurology and Neurological Sciences and Graduate Program in Neuroscience, Stanford University School of Medicine, Stanford, California 94305, USA
    J Neurosci 29:15355-65. 2009
  7. pmc Structure-function studies of the SLC17 transporter sialin identify crucial residues and substrate-induced conformational changes
    Pascal Courville
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    J Biol Chem 285:19316-23. 2010
  8. ncbi request reprint Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamate
    Juliette Johnson
    Department of Ophthalmology, University of California School of Medicine, San Francisco, California 94143 0730, USA
    J Neurosci 23:518-29. 2003
  9. ncbi request reprint Expression of plasma membrane GABA transporters but not of the vesicular GABA transporter in dentate granule cells after kainic acid seizures
    Gunther Sperk
    Department of Pharmacology, University of Innsbruck, Innsbruck, Austria
    Hippocampus 13:806-15. 2003
  10. pmc Vesicular gamma-aminobutyric acid transporter expression in amacrine and horizontal cells
    Juan G Cueva
    Department of Neurobiology, University of California at Los Angeles, Los Angeles, California 90095 1763, USA
    J Comp Neurol 445:227-37. 2002

Collaborators

  • Pascal Courville
  • Robert H Edwards
  • Laura M Prolo
  • Kimberly A Zaia
  • Kyle A Gurley
  • Christopher C Wreden
  • Juliette Johnson
  • Gunther Sperk
  • Farrukh A Chaudhry
  • Juan G Cueva
  • Matthias Quick
  • Hannes Vogel
  • David M Kingsley
  • Marcin Wlizla
  • Matthew S Caywood
  • Ning Tian
  • Jutta Heilman
  • Nathan Nelson
  • Sabine Furtinger
  • David R Copenhagen
  • Christoph Schwarzer
  • Heinz W√§ssle
  • Silke Haverkamp
  • Michael Kavanaugh
  • Dietmar Schmitz
  • Andrew T Gray
  • Roger Nicoll
  • Nicholas C Brecha
  • Peter Larsson
  • Robert Edwards

Detail Information

Publications11

  1. doi request reprint SLC17: a functionally diverse family of organic anion transporters
    Richard J Reimer
    Neurogenetics Division Department of Neurology and Neurological Sciences, Stanford University School of Medicine, P211 MSLS, 1201 Welch Road, Stanford, CA 94305, USA
    Mol Aspects Med 34:350-9. 2013
    ....
  2. ncbi request reprint Organic anion transport is the primary function of the SLC17/type I phosphate transporter family
    Richard J Reimer
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, CA 94305, Stanford, USA
    Pflugers Arch 447:629-35. 2004
    ....
  3. ncbi request reprint Varied mechanisms underlie the free sialic acid storage disorders
    Christopher C Wreden
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    J Biol Chem 280:1408-16. 2005
    ..This analysis of the molecular mechanism of sialic acid storage disorders is a further step in identifying therapeutic approaches to these diseases...
  4. pmc Biochemical and genetic analysis of ANK in arthritis and bone disease
    Kyle A Gurley
    Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Hum Genet 79:1017-29. 2006
    ..The combination of biochemical and genetic analyses presented here provides insight into how mutations in ANKH cause human skeletal disease...
  5. pmc Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport
    Kimberly A Zaia
    Department of Neurology and Neurological Sciences and Neuroscience Graduate Program, Stanford University, Stanford, California 94305, USA
    J Biol Chem 284:8439-48. 2009
    ..This characterization of NTT4/XT1 offers important insights into neurotransmitter metabolism as well as the mechanistic differences among the structurally related, but functionally divergent, SLC6 proteins...
  6. pmc The lysosomal sialic acid transporter sialin is required for normal CNS myelination
    Laura M Prolo
    Department of Neurology and Neurological Sciences and Graduate Program in Neuroscience, Stanford University School of Medicine, Stanford, California 94305, USA
    J Neurosci 29:15355-65. 2009
    ..These findings suggest that a defect in maturation of cells in the oligodendrocyte lineage leads to increased apoptosis and underlies the myelination defect associated with sialin loss...
  7. pmc Structure-function studies of the SLC17 transporter sialin identify crucial residues and substrate-induced conformational changes
    Pascal Courville
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    J Biol Chem 285:19316-23. 2010
    ..These findings offer a basis for further defining the transport mechanism of sialin and other SLC17 family members...
  8. ncbi request reprint Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamate
    Juliette Johnson
    Department of Ophthalmology, University of California School of Medicine, San Francisco, California 94143 0730, USA
    J Neurosci 23:518-29. 2003
    ..Furthermore, vesicular glutamate transmission likely occurs before ribbon synapse formation in the inner retina...
  9. ncbi request reprint Expression of plasma membrane GABA transporters but not of the vesicular GABA transporter in dentate granule cells after kainic acid seizures
    Gunther Sperk
    Department of Pharmacology, University of Innsbruck, Innsbruck, Austria
    Hippocampus 13:806-15. 2003
    ..GABA could then act on GABA-A receptors, protecting granule cells from overexcitation...
  10. pmc Vesicular gamma-aminobutyric acid transporter expression in amacrine and horizontal cells
    Juan G Cueva
    Department of Neurobiology, University of California at Los Angeles, Los Angeles, California 90095 1763, USA
    J Comp Neurol 445:227-37. 2002
    ..Taken together, these findings demonstrate VGAT immunoreactivity in both amacrine and horizontal cell processes, suggesting these cells contain vesicles that accumulate GABA and glycine, possibly for vesicular release...
  11. ncbi request reprint Glutamine uptake by neurons: interaction of protons with system a transporters
    Farrukh A Chaudhry
    Department of Neurology, University of California San Francisco School of Medicine, San Francisco, California 94143 0435, USA
    J Neurosci 22:62-72. 2002
    ..Differences between System N and A transporters in coupling to H+ thus contribute to the delivery of glutamine from glia to neurons. Nonetheless, although they are not transported, H+ inhibit SA1 and SA2 by competing with Na+...

Research Grants6

  1. Molecular Mechanisms of Vesicular Glutamate Transport
    RICHARD REIMER; Fiscal Year: 2007
    ....
  2. Pathophysiology of Lysosomal Free Sialic Acid Storage Disorders
    RICHARD REIMER; Fiscal Year: 2007
    ..Progress in these aims will lead to an improved understanding of the normal function of this transport protein and insight into the pathophysiology of these diseases. ..
  3. Pathophysiology of Lysosomal Free Sialic Acid Storage Disorders
    Richard J Reimer; Fiscal Year: 2010
    ..Progress in these aims will lead to an improved understanding of the normal function of this transport protein and insight into the pathophysiology of these diseases. ..