G M Reaven

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Insulin resistance and coronary heart disease in nondiabetic individuals
    Gerald Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Falk CVRC Stanford Medical Center, 300 Pasteur Dr, Stanford, CA 94306, USA
    Arterioscler Thromb Vasc Biol 32:1754-9. 2012
  2. doi request reprint Relationships among insulin resistance, type 2 diabetes, essential hypertension, and cardiovascular disease: similarities and differences
    Gerald M Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Clin Hypertens (Greenwich) 13:238-43. 2011
  3. doi request reprint The metabolic syndrome: time to get off the merry-go-round?
    G M Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Intern Med 269:127-36. 2011
  4. ncbi request reprint Interaction of diabetes and hypertension on determinants of endothelial adhesiveness
    P S Tsao
    Department of Medicine, Stanford University School of Medicine, Calif 94305 5406, USA
    Arterioscler Thromb Vasc Biol 18:947-53. 1998
  5. doi request reprint Pioglitazone increases the proportion of small cells in human abdominal subcutaneous adipose tissue
    Tracey M McLaughlin
    Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Obesity (Silver Spring) 18:926-31. 2010
  6. ncbi request reprint Effect of insulin resistance on postprandial elevations of remnant lipoprotein concentrations in postmenopausal women
    H S Kim
    Department of Medicine, Stanford University School of Medicine, California 94305, USA
    Am J Clin Nutr 74:592-5. 2001
  7. ncbi request reprint Metabolic changes following sibutramine-assisted weight loss in obese individuals: role of plasma free fatty acids in the insulin resistance of obesity
    T McLaughlin
    Department of Medicine, Stanford University, School of Medicine, Stanford, CA, USA
    Metabolism 50:819-24. 2001
  8. doi request reprint Pioglitazone decreases postprandial accumulation of remnant lipoproteins in insulin-resistant smokers
    F Abbasi
    Department of Medicine, Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Diabetes Obes Metab 11:779-85. 2009
  9. pmc Adiposity indices in the prediction of metabolic abnormalities associated with cardiovascular disease in non-diabetic adults
    A Liu
    Division of Endocrinology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Nutr Metab Cardiovasc Dis 21:553-60. 2011
  10. ncbi request reprint [Insulin resistance: why is it important to treat?]
    G M Reaven
    Professor of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Diabetes Metab 27:247-53. 2001

Collaborators

Detail Information

Publications27

  1. doi request reprint Insulin resistance and coronary heart disease in nondiabetic individuals
    Gerald Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Falk CVRC Stanford Medical Center, 300 Pasteur Dr, Stanford, CA 94306, USA
    Arterioscler Thromb Vasc Biol 32:1754-9. 2012
    ..Resistance to insulin-mediated glucose disposal and hyperinsulinemia is a common finding in apparently healthy individuals and is associated with a number of abnormalities that greatly increase risk of CHD...
  2. doi request reprint Relationships among insulin resistance, type 2 diabetes, essential hypertension, and cardiovascular disease: similarities and differences
    Gerald M Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Clin Hypertens (Greenwich) 13:238-43. 2011
    ....
  3. doi request reprint The metabolic syndrome: time to get off the merry-go-round?
    G M Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Intern Med 269:127-36. 2011
    ..The most important conclusion is that the MetS seems to be less effective in this population than the Framingham Risk Score in predicting CVD, and no better, if not worse, than fasting plasma glucose concentrations in predicting 2DM...
  4. ncbi request reprint Interaction of diabetes and hypertension on determinants of endothelial adhesiveness
    P S Tsao
    Department of Medicine, Stanford University School of Medicine, Calif 94305 5406, USA
    Arterioscler Thromb Vasc Biol 18:947-53. 1998
    ..Furthermore, there appears to be an additive interaction between hyperglycemia and hypertension in their effects on endothelial adhesiveness and its determinants...
  5. doi request reprint Pioglitazone increases the proportion of small cells in human abdominal subcutaneous adipose tissue
    Tracey M McLaughlin
    Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Obesity (Silver Spring) 18:926-31. 2010
    ..These findings support the hypothesis that defects in subcutaneous fat storage may underlie obesity-associated insulin resistance...
  6. ncbi request reprint Effect of insulin resistance on postprandial elevations of remnant lipoprotein concentrations in postmenopausal women
    H S Kim
    Department of Medicine, Stanford University School of Medicine, California 94305, USA
    Am J Clin Nutr 74:592-5. 2001
    ..001). CONCLUSIONS: Postprandial accumulation of RLPs is accentuated in insulin-resistant, postmenopausal women. This may contribute to the increased risk of CAD in these individuals...
  7. ncbi request reprint Metabolic changes following sibutramine-assisted weight loss in obese individuals: role of plasma free fatty acids in the insulin resistance of obesity
    T McLaughlin
    Department of Medicine, Stanford University, School of Medicine, Stanford, CA, USA
    Metabolism 50:819-24. 2001
    ....
  8. doi request reprint Pioglitazone decreases postprandial accumulation of remnant lipoproteins in insulin-resistant smokers
    F Abbasi
    Department of Medicine, Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Diabetes Obes Metab 11:779-85. 2009
    ..More recently, it has been suggested that an increase in non-fasting triglycerides, rather than fasting hypertriglyceridaemia, is an independent CVD risk factor...
  9. pmc Adiposity indices in the prediction of metabolic abnormalities associated with cardiovascular disease in non-diabetic adults
    A Liu
    Division of Endocrinology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Nutr Metab Cardiovasc Dis 21:553-60. 2011
    ....
  10. ncbi request reprint [Insulin resistance: why is it important to treat?]
    G M Reaven
    Professor of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Diabetes Metab 27:247-53. 2001
    ..Compounds that improve insulin sensitivity and lead to lower glucose and insulin concentrations may have unique clinical benefit in the treatment of patients with type 2 diabetes...
  11. ncbi request reprint Insulin resistance and human disease: a short history
    G M Reaven
    Stanford University School of Medicine, South San Francisco, CA, USA
    J Basic Clin Physiol Pharmacol 9:387-406. 1998
    ..In this review an effort has been made to trace a brief history of insulin resistance from its inception to its current position as the fundamental abnormality in both type 2 diabetes and Syndrome X...
  12. ncbi request reprint Insulin resistance: a chicken that has come to roost
    G M Reaven
    Stanford University School of Medicine, California 93405, USA
    Ann N Y Acad Sci 892:45-57. 1999
    ..I resistance is a physiological characteristic, genetically determined, that helped primitive humans to survive. It is greatly aggravated by obesity and physical inactivity, and represents a modern scourge...
  13. ncbi request reprint Enhanced monocyte adherence to thoracic aortae from rats with two forms of experimental hypertension
    T Asagami
    Department of Medicine, Stanford University School of Medicine, California, USA
    Am J Hypertens 12:890-3. 1999
    ..7 +/- 0.2 v 1.1 +/-0.1, P < .05). These results provide evidence that hypertension in Dahl-S and fructose-fed S-D rats was associated with changes in the endothelium that favor atherogenesis...
  14. ncbi request reprint Masoprocol lowers blood pressure in rats with fructose-induced hypertension
    M S Gowri
    Stanford University School of Medicine, California, USA
    Am J Hypertens 12:744-6. 1999
    ....
  15. ncbi request reprint Hemostatic abnormalities associated with obesity and the metabolic syndrome
    G M Reaven
    Division of Cardiovascular Medicine, Falk CVRC, Stanford Medical Center, Stanford, CA 94305 5406, USA
    J Thromb Haemost 3:1074-85. 2005
  16. ncbi request reprint Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis
    T McLaughlin
    Division of Endocrinology, Department of Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Diabetologia 50:1707-15. 2007
    ....
  17. ncbi request reprint Insulin resistance, the insulin resistance syndrome, and cardiovascular disease
    G M Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Panminerva Med 47:201-10. 2005
    ..Indeed, efforts to try to do so by the use of multiple regression analysis of epidemiological data may be more misleading than helpful...
  18. ncbi request reprint Comparison of the hemodynamic and metabolic effects of low-dose hydrochlorothiazide and lisinopril treatment in obese patients with high blood pressure
    G M Reaven
    Department of Medicine, Stanford University School of Medicine, USA
    Am J Hypertens 8:461-6. 1995
    ..In conclusion blood pressure decreased significantly following treatment with either lisinopril (20 mg/day) or hydrochlorothiazide (12.5 mg/day).(ABSTRACT TRUNCATED AT 250 WORDS)..
  19. ncbi request reprint PPARgamma agonists enhance human vascular endothelial adhesiveness by increasing ICAM-1 expression
    N G Chen
    Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Biochem Biophys Res Commun 263:718-22. 1999
    ..These findings suggest that the PPARgamma signaling pathway might contribute to the atherogenicity of oxLDL in vascular endothelial cells...
  20. ncbi request reprint Improvement in insulin sensitivity followed by ovulation and pregnancy in a woman with polycystic ovary syndrome who was treated with rosiglitazone
    N A Cataldo
    Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Stanford University Medical Center, California 94305 5317, USA
    Fertil Steril 76:1057-9. 2001
    ..To determine the metabolic and reproductive effectiveness of rosiglitazone in polycystic ovary syndrome (PCOS)...
  21. ncbi request reprint Insulin resistance in patients with essential hypertension can occur in the absence of microalbuminuria
    J W Yip
    Department of Medicine, Stanford University School of Medicine, California, USA
    Am J Hypertens 9:959-63. 1996
    ..These results demonstrate that insulin resistance, glucose intolerance, and hyperinsulinemia can occur independently of microalbuminuria in patients with hypertension...
  22. ncbi request reprint The relationship between insulin resistance and dyslipidaemia in cigarette smokers
    H M F Farin
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Diabetes Obes Metab 9:65-9. 2007
    ..The present study was initiated to determine whether this dyslipidaemia prevalent in cigarette smokers and characteristic of insulin-resistant individuals is a function of cigarette smoking or of insulin resistance...
  23. pmc Insulin resistance in pulmonary arterial hypertension
    R T Zamanian
    Division of Pulmonary and Critical Care Medicine, 300 Pasteur Dr, Room H3147, Stanford, CA 94305, USA
    Eur Respir J 33:318-24. 2009
    ..Insulin resistance appears to be more common in pulmonary arterial hypertension females than in the general population, and may be a novel risk factor or disease modifier that might impact on survival...
  24. ncbi request reprint Enhanced sympathetic nervous system activity. The linchpin between insulin resistance, hyperinsulinemia, and heart rate
    F S Facchini
    Department of Medicine, Stanford University School of Medicine, California, USA
    Am J Hypertens 9:1013-7. 1996
    ....
  25. ncbi request reprint Lipoprotein risk factors for cardiovascular disease in patients with type 2 diabetes mellitus treated with oral antihyperglycaemic agents
    J W Chu
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Diabetes Obes Metab 5:333-7. 2003
    ..To compare lipoprotein risk factors for cardiovascular disease (CVD) in patients with type 2 diabetes mellitus (DM) treated with a sulphonylurea (SU) compound only, metformin (MET) only, or combined SU + MET...
  26. ncbi request reprint Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes
    T Asagami
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Metabolism 51:843-6. 2002
    ....
  27. ncbi request reprint Evaluation of the quantitative insulin sensitivity check index as an estimate of insulin sensitivity in humans
    F Abbasi
    Department of Medicine, Stanford University, School of Medicine Stanford, CA 94305, USA
    Metabolism 51:235-7. 2002
    ..Furthermore, none of the 3 surrogate estimates can account for more than approximately 40% of the variability of the difference in insulin-mediated glucose disposal measured directly in 490 healthy, nondiabetic volunteers...