Research Topics
Species | Natalie L RasgonSummaryAffiliation: Stanford University Country: USA Publications
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Publications
Metabolic dysfunction in women with bipolar disorder: the potential influence of family history of type 2 diabetes mellitusNatalie L Rasgon
Stanford Center for Neuroscience in Women s Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5723, USA
Bipolar Disord 12:504-13. 2010..Family history of type 2 diabetes mellitus (FamHxDM2), which has been shown to have deleterious effects on metabolic function in the general population, may play a role in the metabolic dysfunction observed in BD...- Estrogen and response to sertraline in postmenopausal women with major depressive disorder: a pilot studyNatalie L Rasgon
Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences, 410 Quarry Road, Room 2368, Palo Alto, CA 94305 5723, USA
J Psychiatr Res 41:338-43. 2007..Pilot study examining the effects of estrogen therapy (ET) on antidepressant response in postmenopausal women with major depressive disorder (MDD)... - Cerebral metabolic patterns in untreated postmenopausal women with major depressive disorderNatalie L Rasgon
Stanford Center for Neuroscience in Women s Health, Department of Psychiatry and Behavioral Sciences, 401 Quarry Road, Stanford University School of Medicine, Stanford, CA, United States
Psychiatry Res 164:77-80. 2008..All subjects were hormone therapy-naive and medication-free. Findings include hypermetabolism in the middle frontal gyrus and Broca regions, and hypometabolism in the pons among depressed compared with non-depressed women... - Insulin resistance in depressive disorders and Alzheimer's disease: revisiting the missing link hypothesisNatalie L Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 5723, USA
Neurobiol Aging 26:103-7. 2005..Herein, we review the IR link in depressive disorders and AD and describe the results of our studies and others in support of this hypothesis... - Longitudinal evaluation of reproductive function in women treated for bipolar disorderNatalie L Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford University, 401 Quarry Road, Palo Alto, Ca 94305 5723 Stanford, California, United States
J Affect Disord 89:217-25. 2005..We assessed reproductive endocrine and metabolic markers in women treated for bipolar disorder over a 2-year time period, controlling for valproate use... - Perimenopausal mental disorders: epidemiology and phenomenologyNatalie Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Standord, CA 94305 5723, USA
CNS Spectr 10:471-8. 2005..At this time, more research is needed to address questions of prevalence, risk, and etiology for depression and other major mental disorders as related to the physiological and psychosocial changes associated with perimenopause... - Reproductive function and risk for PCOS in women treated for bipolar disorderNatalie L Rasgon
Department of Psychiatry, Stanford School of Medicine, Palo Alto, CA, USA
Bipolar Disord 7:246-59. 2005..This study examined the reproductive function and prevalence of polycystic ovary syndrome (PCOS) in women with bipolar disorder taking antimanic medications... - Endogenous and exogenous hormone exposure and risk of cognitive impairment in Swedish twins: a preliminary studyNatalie L Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford University, School of Medicine, 401 Quarry Road, Room 2360, Palo Alto, CA 94305 5723, USA
Psychoneuroendocrinology 30:558-67. 2005..To analyze the risk of cognitive impairment among female Swedish Twins with regard to endogenous and exogenous hormone exposure... - Estrogen use and brain metabolic change in postmenopausal womenNatalie L Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
Neurobiol Aging 26:229-35. 2005..We used positron emission tomography to evaluate cerebral glucose metabolic change in postmenopausal women in a naturalistic observational study... - The relationship between polycystic ovary syndrome and antiepileptic drugs: a review of the evidenceNatalie Rasgon
Department of Psychiatry, Stanford School of Medicine, 401 Quarry Road, Room 2360, Palo Alto, CA 94305 5723, USA
J Clin Psychopharmacol 24:322-34. 2004..Despite this concern, the choice of antiepileptic drug for women with epilepsy or bipolar disorder should be based on the most effective agent for controlling neurologic symptoms... - Insulin resistance, affective disorders, and Alzheimer's disease: review and hypothesisNatalie Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, USA
J Gerontol A Biol Sci Med Sci 59:178-83; discussion 184-92. 2004..Persistent regional hypometabolism and vascular changes resulting from long-standing IR may lead to currently irreversible structural changes. Evidence in support of the hypothesis is reviewed and clinical implications suggested... - Emergent oscillations in a mathematical model of the human menstrual cycleNatalie L Rasgon
Department of Psychiatry and Biobehavioral Sciences, Stanford School of Medicine, Palo Alto, California 94305, USA
CNS Spectr 8:805-14. 2003..The aim of this study was to develop a mathematical model of the hypothalamo-pituitary-gonadal axis that would reflect available data in humans... - Insulin resistance and hippocampal volume in women at risk for Alzheimer's diseaseNatalie L Rasgon
Stanford Center for Neuroscience in Women s Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stan ford, CA 94305 5723, USA
Neurobiol Aging 32:1942-8. 2011..These results suggest that IR in middle-aged individuals at risk for AD may be biomarker for dementia risk... - Menstrual cycle related mood changes in women with bipolar disorderNatalie Rasgon
Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute and Hospital, University of California Los Angeles, CA, USA
Bipolar Disord 5:48-52. 2003..This study investigates the influence of the menstrual cycle on mood in women with BPD who are taking medication, but not selected for menstrual abnormalities... - Rosiglitazone add-on in treatment of depressed patients with insulin resistance: a pilot studyNatalie L Rasgon
Stanford Center for Neuroscience in Women s Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
ScientificWorldJournal 10:321-8. 2010..These results suggest the potential novel use for an insulin-sensitizing agent in the treatment of depressive disorders. Larger placebo-controlled studies are warranted... - Hypothalamic-pituitary-end organ function in women with bipolar depressionNatalie L Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305 5723, USA
Psychoneuroendocrinology 32:279-86. 2007..The results are preliminary, and require replication in larger samples... - Increased depressive symptoms in menopausal age women with bipolar disorder: age and gender comparisonWendy K Marsh
Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Psychiatr Res 43:798-802. 2009..This study examines the course of bipolar disorder focusing on depressive symptoms in menopausal transition age women, compared to similar-aged men as well as younger adult women and men... - Mood and neuropsychological changes in women with midlife depression treated with escitalopramTonita E Wroolie
Behavioral Neuroendocrinology Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
J Clin Psychopharmacol 26:361-6. 2006.... - Differences in verbal memory performance in postmenopausal women receiving hormone therapy: 17β-estradiol versus conjugated equine estrogensTonita E Wroolie
Stanford Center for Neuroscience in Women s Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94303 5723, USA
Am J Geriatr Psychiatry 19:792-802. 2011..The present study sought to further examine this issue in a sample of postmenopausal women with risk factors for Alzheimer's disease (AD)... - Gender-specific lipid profiles in patients with bipolar disorderMytilee Vemuri
Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford, CA 94305 5723, USA
J Psychiatr Res 45:1036-41. 2011..High rates of dyslipidemia and insulin resistance (IR) are reported in patients with bipolar disorder (BD). We assessed gender effects upon rates of dyslipidemia/IR in outpatients with BD... - Reproductive and metabolic abnormalities associated with bipolar disorder and its treatmentHeather A Kenna
Center for Neuroscience in Women s Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5723, USA
Harv Rev Psychiatry 17:138-46. 2009..Current understanding of the reproductive and metabolic function in women with BD points to vulnerability, which in turn increases the risk of later-life cardiovascular disease and diabetes, among other morbidities, for women with BD... - Depression in women with polycystic ovary syndrome: clinical and biochemical correlatesNatalie L Rasgon
Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles School of Medicine, Mood Disorders Research Program, 300 Medical Plaza, Suite 1544, Los Angeles, CA 90095 7057, USA
J Affect Disord 74:299-304. 2003..We assessed the prevalence of mood disturbance among women with prospectively documented polycystic ovary syndrome (PCOS)... - Thalamo-Basal Ganglia connectivity in postmenopausal women receiving estrogen therapyHeather A Kenna
Department of Psychiatry and Behavioral Sciences, Stanford Center for Neuroscience in Women s Health, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA, USA
Neurochem Res 34:234-7. 2009..The results also suggest that ET initiated at or near the menopausal transition may modulate brain aging by mediating complex sensory-motor functions... - Mood disorders in oocyte donor candidates: brief report and implications for future researchKatherine E Williams
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Room 2358, Stanford, CA 94305 5723, USA
Hum Reprod 26:847-52. 2011..Measures that examine whether a candidate donor may have a tendency to present herself in an overly favorable manner, and/or a tendency to minimize symptoms, are recommended... - Mood symptoms and cognitive performance in women estrogen users and nonusers and menKaren J Miller
Department of Psychiatry and Biobehavioral Sciences, The Neuropsychiatric Institute, University of California, Los Angeles, CA 90024, USA
J Am Geriatr Soc 50:1826-30. 2002..In this study, we explore sex differences for a range of mood symptoms and for neuropsychological performance in men and postmenopausal women and assess the potential influence of estrogen on these measures... - Increased frequency of depressive episodes during the menopausal transition in women with bipolar disorder: preliminary reportWendy K Marsh
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, United States
J Psychiatr Res 42:247-51. 2008..The menopausal transition in women without mood disorders is associated with an increase in depression. This study assesses mood course during the menopausal transition in women with bipolar disorder... - Open adjunctive ziprasidone associated with weight loss in obese and overweight bipolar disorder patientsPo W Wang
Stanford University School of Medicine, Stanford, CA, USA
J Psychiatr Res 45:1128-32. 2011..To assess effectiveness and tolerability of open adjunctive ziprasidone for weight loss in obese/overweight patients with bipolar disorders (BD) in diverse mood states, taking weight gain-implicated psychotropic medications... - Genetic overlap between polycystic ovary syndrome and bipolar disorder: the endophenotype hypothesisBowen Jiang
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Center for Neuroscience in Women s Health, 401 Quarry Road, Stanford, CA 94305, United States
Med Hypotheses 73:996-1004. 2009..This paper postulates that shared clinical endophenotypes between PCOS and BD indicate common pathophysiological platforms and will review these for the potential of genetic overlap between the two disorders... - Mood disorders and fertility in women: a critical review of the literature and implications for future researchKatherine E Williams
Stanford Center for Neuroscience in Women s Health, Department of Psychiatry and Behavioural Sciences, Stanford University and Hospitals, Stanford, CA 94305, USA
Hum Reprod Update 13:607-16. 2007.... - Sex-specific self-reported mood changes by patients with bipolar disorderNatalie Rasgon
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Room 2360, Palo Alto, CA 94305-5723, USA
J Psychiatr Res 39:77-83. 2005..CONCLUSIONS: The clinical course of bipolar disorder differed between the sexes. Women reported depression and large fluctuations in mood more frequently than men. Women also experienced mood changes across the menstrual cycle... - Metabolic and endocrine disturbances in psychiatric disorders: a multidisciplinary approach to appropriate atypical antipsychotic utilizationPrakash S Masand
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina, USA
CNS Spectr 10:suppl14 1-15. 2005.... - Children of persons with Alzheimer disease: what does the future hold?Lissy Jarvik
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA
Alzheimer Dis Assoc Disord 22:6-20. 2008..We examine the state of knowledge with respect to risk and protective factors for AD and recommend a research agenda with special emphasis on AD offspring... - Verbal memory retrieval deficits associated with untreated hypothyroidismKaren J Miller
Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Behavioral Sciences, University of California, Los Angeles, USA
J Neuropsychiatry Clin Neurosci 19:132-6. 2007..There were no significant results found between groups on attentional or nonverbal tasks. Results suggest that hypothyroid-related memory deficits are not attributable to an attentional deficit but rather to specific retrieval deficits... - Self-reported data from patients with bipolar disorder: frequency of brief depressionMichael Bauer
Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Germany
J Affect Disord 101:227-33. 2007..Using daily self-reported mood ratings, we studied how changing the length requirement to that typical of recurrent brief depression (2-4 days) would impact the number of depressed episodes... - Estrogen replacement therapy in the treatment of major depressive disorder in perimenopausal womenNatalie L Rasgon
Department of Psychiatry and Biobehavioral Science, University of California, Los Angeles, USA
J Clin Psychiatry 63:45-8. 2002..In depressed women who have minimal response to a selective serotonin reuptake inhibitor, ERT may augment response. Further controlled trials are needed... - A case of olanzapine-induced gestational diabetes mellitus in the absence of weight gainMytilee P Vemuri
J Clin Psychiatry 68:1989. 2007 - Self-reported data from patients with bipolar disorder: impact on minimum episode length for hypomaniaMichael Bauer
Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Schumannstr 20 21, 10117 Berlin, Germany
J Affect Disord 96:101-5. 2006..Using daily self-reported mood ratings, we studied the impact of changing the length requirement on the number of hypomanic episodes in patients with bipolar disorder...
Research Grants
- ERT, DEPRESSION AND COGNITION IN POSTMENOPAUSAL WOMENNatalie Rasgon; Fiscal Year: 2002..antidepressant alone. This research will be the foundation for a future investigation of pathophysiology of reproductive-related mood disorders. ..
- Estrogen Use in Protection from Cognitive DeclineNatalie Rasgon; Fiscal Year: 2007..abstract_text> ..
- Endocrine Function and Mood in Bipolar DisorderNatalie Rasgon; Fiscal Year: 2007..abstract_text> ..
- Estrogen Use in Protection from Cognitive DeclineNatalie L Rasgon; Fiscal Year: 2010..abstract_text> ..