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Genomes and Genes | Justin I OdegaardSummaryAffiliation: Stanford University Country: USA Publications
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Publications
Alternative macrophage activation and metabolismJustin I Odegaard
Department of Pathology, Stanford University School of Medicine, California 94305 5103, USA
Annu Rev Pathol 6:275-97. 2011..The therapeutic implications of this conclusion are profound because they suggest that pharmacologic targeting of macrophage activation, rather than simply inflammation, might be efficacious in treating this global epidemic...- Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistanceJustin I Odegaard
Division of Endocrinology, Metabolism and Gerontology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5103, USA
Cell Metab 7:496-507. 2008..Taken together, these data suggest an unexpected beneficial role for alternatively activated Kupffer cells in metabolic syndrome and type 2 diabetes... - IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivityRoberto R Ricardo-Gonzalez
Division of Endocrinology, Metabolism and Gerontology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 107:22617-22. 2010.... - PPAR-delta senses and orchestrates clearance of apoptotic cells to promote toleranceLata Mukundan
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
Nat Med 15:1266-72. 2009..Thus, PPAR-delta has a pivotal role in orchestrating the timely disposal of apoptotic cells by macrophages, ensuring that tolerance to self is maintained... - Quantitative expansion of ES cell-derived myeloid progenitors capable of differentiating into macrophagesJustin I Odegaard
Division of Endocrinology, Metabolism and Gerontology, Department of Medicine and Graduate Program in Immunology, Stanford University School of Medicine, Stanford, CA 94305 5103, USA
J Leukoc Biol 81:711-9. 2007.... - Macrophage-specific PPARgamma controls alternative activation and improves insulin resistanceJustin I Odegaard
Division of Endocrinology, Metabolism and Gerontology, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305 5103, USA
Nature 447:1116-20. 2007.... - Mechanisms of macrophage activation in obesity-induced insulin resistanceJustin I Odegaard
Graduate Program in Immunology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5103, USA
Nat Clin Pract Endocrinol Metab 4:619-26. 2008..The functional importance of macrophage activation is further discussed in the context of host defense to highlight the crosstalk between innate immunity and metabolism... - Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammationDivya Vats
Division of Endocrinology, Metabolism and Gerontology, Department of Medicine and Graduate Program in Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
Cell Metab 4:13-24. 2006.... - Connecting type 1 and type 2 diabetes through innate immunityJustin I Odegaard
Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
Cold Spring Harb Perspect Med 2:a007724. 2012..We conclude with a discussion of the therapeutic implications of this integrated understanding of diabetic pathology...