Affiliation: Stanford University
- Motor behavior activates Bergmann glial networksAxel Nimmerjahn
James H Clark Center for Biomedical Engineering and Sciences, Stanford University, Stanford, CA 94305, USA
Neuron 62:400-12. 2009..Thus, large networks of Bergmann glia can be activated by specific animal behaviors and undergo excitation of sufficient magnitude to potentially initiate macroscopic changes in brain dynamics or blood flow...
- Astrocytes going live: advances and challengesAxel Nimmerjahn
Department of Biology, James H Clark Center for Biomedical Engineering and Sciences, Stanford University, Stanford, CA 94305 5435, USA
J Physiol 587:1639-47. 2009..This review will summarize some of their most intriguing findings, discuss some of their implications, and look ahead at some of the challenges we face in studying astrocyte function in vivo...
- Miniaturized integration of a fluorescence microscopeKunal K Ghosh
David Packard Electrical Engineering Building, Stanford University, Stanford, California, USA
Nat Methods 8:871-8. 2011..Overall, the integrated microscope is a potentially transformative technology that permits distribution to many animals and enables diverse usages, such as portable diagnostics or microscope arrays for large-scale screens...
- Automated analysis of cellular signals from large-scale calcium imaging dataEran A Mukamel
James H Clark Center for Biomedical Engineering and Sciences, Stanford University, Stanford CA 94305, USA
Neuron 63:747-60. 2009..Using this approach, we found microzones of Purkinje cells that were stable across behavioral states and in which synchronous Ca(2+) spiking rose significantly during locomotion...
- High-speed, miniaturized fluorescence microscopy in freely moving miceBenjamin A Flusberg
James H Clark Center for Biomedical Engineering and Sciences, Stanford University, 318 Campus Drive, Stanford, California 94305, USA
Nat Methods 5:935-8. 2008..We describe a miniaturized (1.1 g mass) epifluorescence microscope for cellular-level brain imaging in freely moving mice, and its application to imaging microcirculation and neuronal Ca(2+) dynamics...