Khoa D Nguyen

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Serum amyloid A induces mitogenic signals in regulatory T cells via monocyte activation
    Khoa D Nguyen
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA Electronic address
    Mol Immunol 59:172-9. 2014
  2. pmc TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway
    Khoa D Nguyen
    Department of Pediatrics, Stanford University, Stanford, CA, USA
    Allergy Asthma Clin Immunol 6:4. 2010
  3. pmc Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways
    Khoa D Nguyen
    Department of Pediatrics, Immunology Program, Stanford University School of Medicine, 259 Campus Drive, Stanford, CA 94305, USA
    Blood 117:3793-8. 2011
  4. doi request reprint Impaired IL-10-dependent induction of tolerogenic dendritic cells by CD4+CD25hiCD127lo/- natural regulatory T cells in human allergic asthma
    Khoa D Nguyen
    Department of Pediatrics, Stanford University, Stanford, California 94305, USA
    Am J Respir Crit Care Med 180:823-33. 2009
  5. pmc Alternative activation in systemic juvenile idiopathic arthritis monocytes
    Claudia Macaubas
    Department of Pediatrics, Program in Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Clin Immunol 142:362-72. 2012
  6. pmc Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development
    Diana Milojevic
    Department of Pediatrics, UCSF, San Francisco, CA 94143, USA
    Pediatr Rheumatol Online J 6:20. 2008
  7. pmc Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications
    Xuefeng B Ling
    Department of Pediatrics, Stanford University, Stanford, CA 94305 5164, USA
    Proteomics 10:4415-30. 2010
  8. pmc Eosinophils secrete IL-4 to facilitate liver regeneration
    Y P Sharon Goh
    Department of Genetics and Pathology, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 110:9914-9. 2013

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Serum amyloid A induces mitogenic signals in regulatory T cells via monocyte activation
    Khoa D Nguyen
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA Electronic address
    Mol Immunol 59:172-9. 2014
    ..Collectively, these results point to a novel mechanism, by which SAA initiates a monocyte-dependent process that drives mitogenic signals in Treg. ..
  2. pmc TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway
    Khoa D Nguyen
    Department of Pediatrics, Stanford University, Stanford, CA, USA
    Allergy Asthma Clin Immunol 6:4. 2010
    ..TSLP mediated inhibition of Treg function might present a novel pathologic mechanism to dampen tolerogenic immune responses in inflamed asthmatic airway...
  3. pmc Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways
    Khoa D Nguyen
    Department of Pediatrics, Immunology Program, Stanford University School of Medicine, 259 Campus Drive, Stanford, CA 94305, USA
    Blood 117:3793-8. 2011
    ..Collectively, these evidences suggest a novel anti-inflammatory role of SAA in the induction of a micro-environment that supports T(reg) expansion at sites of infection or tissue injury, likely to curb (auto)-inflammatory responses...
  4. doi request reprint Impaired IL-10-dependent induction of tolerogenic dendritic cells by CD4+CD25hiCD127lo/- natural regulatory T cells in human allergic asthma
    Khoa D Nguyen
    Department of Pediatrics, Stanford University, Stanford, California 94305, USA
    Am J Respir Crit Care Med 180:823-33. 2009
    ..However, the significance of the influence of natural regulatory T cells on tolerogenic dendritic cells in the disease has not been investigated...
  5. pmc Alternative activation in systemic juvenile idiopathic arthritis monocytes
    Claudia Macaubas
    Department of Pediatrics, Program in Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Clin Immunol 142:362-72. 2012
    ..The persistence of some of these phenotypes during clinically inactive disease argues that this state reflects compensated inflammation...
  6. pmc Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development
    Diana Milojevic
    Department of Pediatrics, UCSF, San Francisco, CA 94143, USA
    Pediatr Rheumatol Online J 6:20. 2008
    ..We also review the literature on the role of these T cells in rheumatic diseases and discuss the potential for their use in immunotherapy...
  7. pmc Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications
    Xuefeng B Ling
    Department of Pediatrics, Stanford University, Stanford, CA 94305 5164, USA
    Proteomics 10:4415-30. 2010
    ..Pathway analyses of the 15 proteins in the SJIA flare versus quiescence signature corroborate growing evidence for a key role for IL-1 at disease flare...
  8. pmc Eosinophils secrete IL-4 to facilitate liver regeneration
    Y P Sharon Goh
    Department of Genetics and Pathology, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 110:9914-9. 2013
    ..Instead, IL-4 exerts its proliferative actions via IL-4Rα in hepatocytes. Our findings thus provide a unique mechanism by which eosinophil-derived IL-4 stimulates hepatocyte proliferation in regenerating liver...