Jason D Merker

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes
    Jason D Merker
    Haematologica 98:1689-96. 2013
  2. pmc Design and evaluation of a real-time PCR assay for quantification of JAK2 V617F and wild-type JAK2 transcript levels in the clinical laboratory
    Jason D Merker
    Department of Pathology, Stanford University Medical Center, 300 Pasteur Dr, L235, Stanford, CA 94305 5324, USA
    J Mol Diagn 12:58-64. 2010
  3. ncbi request reprint Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements
    Scott D Boyd
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    J Immunol 184:6986-92. 2010
  4. pmc Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
    Stephen T Oh
    Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford Cancer Center, 875 Blake Wilbur Dr, Stanford, CA 94305 5821, USA
    Blood 116:988-92. 2010
  5. ncbi request reprint Cold agglutinin syndrome in pediatric liver transplant recipients
    Wendy Wong
    Division of Pediatric Hematology, Stanford University Medical Center, Stanford, California 94305, USA
    Pediatr Transplant 11:931-6. 2007
  6. ncbi request reprint Clinical interpretation and implications of whole-genome sequencing
    Frederick E Dewey
    Stanford Center for Inherited Cardiovascular Disease, Stanford, California2Stanford Cardiovascular Institute, Stanford, California3Division of Cardiovascular Medicine, Stanford University, Stanford, California4Stanford Center for Genomics and Personalized
    JAMA 311:1035-45. 2014
  7. pmc Next-generation sequencing in hematologic malignancies: what will be the dividends?
    Jason D Merker
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA
    Ther Adv Hematol 3:333-9. 2012
  8. ncbi request reprint Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system
    Olga K Weinberg
    Department of Pathology, Center for Clinical Investigation, Stanford University Medical Center, CA 94305, USA
    Blood 113:1906-8. 2009
  9. pmc Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing
    Scott D Boyd
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Sci Transl Med 1:12ra23. 2009

Collaborators

Detail Information

Publications9

  1. pmc Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes
    Jason D Merker
    Haematologica 98:1689-96. 2013
    ..Finally, we describe methods for reducing false-positive variant calls in the analysis of hematologic malignancies with a low somatic mutation rate. This trial is registered with ClinicalTrials.gov (NCT01108159). ..
  2. pmc Design and evaluation of a real-time PCR assay for quantification of JAK2 V617F and wild-type JAK2 transcript levels in the clinical laboratory
    Jason D Merker
    Department of Pathology, Stanford University Medical Center, 300 Pasteur Dr, L235, Stanford, CA 94305 5324, USA
    J Mol Diagn 12:58-64. 2010
    ....
  3. ncbi request reprint Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements
    Scott D Boyd
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    J Immunol 184:6986-92. 2010
    ..These deletions significantly alter the potential expressed IGH repertoire, and possibly immune function, in this individual...
  4. pmc Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
    Stephen T Oh
    Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford Cancer Center, 875 Blake Wilbur Dr, Stanford, CA 94305 5821, USA
    Blood 116:988-92. 2010
    ..These findings indicate that JAK-STAT activation due to loss of LNK negative feedback regulation is a novel mechanism of MPN pathogenesis...
  5. ncbi request reprint Cold agglutinin syndrome in pediatric liver transplant recipients
    Wendy Wong
    Division of Pediatric Hematology, Stanford University Medical Center, Stanford, California 94305, USA
    Pediatr Transplant 11:931-6. 2007
    ..Whether the immune-mediated hemolysis is related to tacrolimus is not clear and needs to be characterized further...
  6. ncbi request reprint Clinical interpretation and implications of whole-genome sequencing
    Frederick E Dewey
    Stanford Center for Inherited Cardiovascular Disease, Stanford, California2Stanford Cardiovascular Institute, Stanford, California3Division of Cardiovascular Medicine, Stanford University, Stanford, California4Stanford Center for Genomics and Personalized
    JAMA 311:1035-45. 2014
    ..Whole-genome sequencing (WGS) is increasingly applied in clinical medicine and is expected to uncover clinically significant findings regardless of sequencing indication...
  7. pmc Next-generation sequencing in hematologic malignancies: what will be the dividends?
    Jason D Merker
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA
    Ther Adv Hematol 3:333-9. 2012
    ....
  8. ncbi request reprint Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system
    Olga K Weinberg
    Department of Pathology, Center for Clinical Investigation, Stanford University Medical Center, CA 94305, USA
    Blood 113:1906-8. 2009
    ..001). These data support the clinical, morphologic, and cytogenetic criteria for this 2008 WHO AML category...
  9. pmc Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing
    Scott D Boyd
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Sci Transl Med 1:12ra23. 2009
    ....