Research Topics
Species | Ines MendeSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Flk2+ myeloid progenitors are the main source of Langerhans cellsInes Mende
Stanford Blood Center, 3373 Hillview Ave, Palo Alto, CA 94304, USA
Blood 107:1383-90. 2006..These results indicate that LCs are derived mainly from myeloid progenitors and are dependent on Flt3-ligand for their development...
Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursorsHolger Karsunky
Department of Pathology, Stanford University School of Medicine, Stanford, Calif, USA
Exp Hematol 33:173-81. 2005....
Breaking tolerance to tumors with dendritic cell-based immunotherapyInes Mende
Department of Pathology, Stanford University School of Medicine, Palo Alto, California 94305, USA
Ann N Y Acad Sci 1058:96-104. 2005..Two approaches to DC targeting are described in this review, both of which have been shown to overcome immune tolerance to tumors and induce dramatic tumor regression...
Breaking self-tolerance to tumor-associated antigens by in vivo manipulation of dendritic cellsInes Mende
Department of Pathology, Stanford University School of Medicine, Palo Alto, CA, USA
Methods Mol Biol 380:457-68. 2007..Strategies that allow DC to gain access to both tumor antigens and TLR agonists, in situ, can overcome tumor tolerance leading to the induction of potent systemic antitumor immunity...
High levels of the onco-protein Gfi-1 accelerate T-cell proliferation and inhibit activation induced T-cell death in Jurkat T-cellsHolger Karsunky
, IFZ, , Virchowstrasse 173, D-45122 Essen, Germany
Oncogene 21:1571-9. 2002..These findings suggest that Gfi-1 contributes to T-cell lymphomagenesis by overriding a late G1 cell cycle checkpoint which controls activation induced death and S phase entry of T-cells...
A subset of human dendritic cells in the T cell area of mucosa-associated lymphoid tissue with a high potential to produce TNF-alphaAnnegret de Baey
Micromet AG, Munich, Germany
J Immunol 170:5089-94. 2003..We infer that selective elimination of M-DC8(+) cells in inflammatory diseases has therapeutic potential...
Highly efficient antigen targeting to M-DC8+ dendritic cells via FcgammaRIII/CD16-specific antibody conjugatesInes Mende
Micromet AG, Staffelseestrasse 2, 81477 Munich, Germany
Int Immunol 17:539-47. 2005..Our data demonstrate that specific antigen targeting via CD16 on M-DC8(+) DC is a promising vaccination approach for the efficient induction of specific CD4(+) T cell responses ex vivo, and perhaps in vivo...
Incorporation of CpG oligonucleotide ligand into protein-loaded particle vaccines promotes antigen-specific CD8 T-cell immunityStephany M Standley
Department of Chemistry, University of California, Berkeley, California 94729 1460, USA
Bioconjug Chem 18:77-83. 2007....
