Research Topics
Species | Valerie McGuireSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortiumV McGuire
Department of Health Research and Policy, Division of Epidemiology, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
J Neurol Sci 307:22-9. 2011..To examine genetic associations of polymorphisms in the dopamine receptor D2 (DRD2) and D3 (DRD3) genes with risk of Parkinson's disease (PD)...
No increased risk of breast cancer associated with alcohol consumption among carriers of BRCA1 and BRCA2 mutations ages <50 yearsValerie McGuire
Department of Health Research and Policy, Stanford University School of Medicine, Health Research and Stanford, CA 94305-5405, USA
Cancer Epidemiol Biomarkers Prev 15:1565-7. 2006
Relation of contraceptive and reproductive history to ovarian cancer risk in carriers and noncarriers of BRCA1 gene mutationsV McGuire
Department of Health Research and Policy and Medicine, Stanford University School of Medicine, Stanford, CA, USA
Am J Epidemiol 160:613-8. 2004..26) for carriers and 24% (p < 0.001) for noncarriers). These data suggest that BRCA1 mutation carriers and noncarriers have similar risk reductions associated with oral contraceptive use, tubal ligation, and parity...
Breast and ovarian cancer in relatives of cancer patients, with and without BRCA mutationsJennifer S Lee
Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine, HRP Redwood Building, Stanford, California 94305 5405, USA
Cancer Epidemiol Biomarkers Prev 15:359-63. 2006..Little is known about how their risks vary with the patient's cancer site, carrier status for predisposing genetic mutations, or age at cancer diagnosis...
Effect of non-steroidal anti-inflammatory medications on the risk of amyotrophic lateral sclerosisRita A Popat
Department of Health Research and Policy, Division of Epidemiology, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
Amyotroph Lateral Scler 8:157-63. 2007..This study did not find any evidence to suggest that NSAID use reduces the risk of ALS. The observed sex differences with non-aspirin NSAID use could be due to chance or an unmeasured confounder...
Prevalence of BRCA1 mutation carriers among U.S. non-Hispanic WhitesAlice S Whittemore
Department of Health Research and Policy, Stanford University School of Medicine, Redwood Building, Room T204, Stanford, CA 94503 5405, USA
Cancer Epidemiol Biomarkers Prev 13:2078-83. 2004..S. Whites (506,206 non-Ashkenazim and 44,307 Ashkenazim) carry germ line BRCA1 mutations. These estimates may be useful in guiding resource allocation for genetic testing and genetic counseling and in planning preventive interventions...
Familial aggregation of Parkinson's disease in a multiethnic community-based case-control studyMichael Y Shino
Department of Health Research and Policy, Division of Epidemiology, Stanford University School of Medicine, Stanford, California, USA
Mov Disord 25:2587-94. 2010..4, 95% CI 1.8-16.0) than among parents (RR = 2.7, 95% CI 1.3-5.2). The incidence and familial aggregation of PD is highest among Hispanics, warranting further studies of genetic and environmental risk factors in the Hispanic population...
No evidence of familial correlation in breast cancer metastasisAlice S Whittemore
Department of Health Research and Policy, Stanford University School of Medicine, Redwood Building, Room T204, Stanford, CA, 94305 5405, USA
Breast Cancer Res Treat 118:575-81. 2009..03 (95% confidence interval -0.11 to 0.06). These findings suggest that a family history of metastatic breast cancer does not contribute substantially to risk of metastasis for breast cancer patients...
Race, epithelial ovarian cancer survival, and membership in a large health maintenance organizationValerie McGuire
Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
Epidemiology 13:231-4. 2002..African-American ovarian cancer patients present with more advanced disease and have poorer survival than do white patients...
Histologic types of epithelial ovarian cancer: have they different risk factors?Allison W Kurian
Department of Medicine, Division of Oncology, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA 94305 5820, USA
Gynecol Oncol 96:520-30. 2005..The goals of the current study were to characterize further the relation of histologic-specific ovarian cancer risks to reproductive and lifestyle attributes...
Effect of reproductive factors and postmenopausal hormone use on the risk of amyotrophic lateral sclerosisRita A Popat
Department of Health Research and Policy, Division of Epidemiology, Stanford University School of Medicine, Stanford, Calif, USA
Neuroepidemiology 27:117-21. 2006..To examine the associations of reproductive factors and postmenopausal hormone use with the risk of amyotrophic lateral sclerosis (ALS) among women...
Reliability and validity of two self-administered questionnaires for screening restless legs syndrome in population-based studiesRita A Popat
Dept of Health Research and Policy, Division of Epidemiology, HRP Redwood Building, Room T209, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
Sleep Med 11:154-60. 2010..We evaluated the reliability and validity of this RLS-NIH questionnaire in a community-based sample and concurrently developed and evaluated the utility of an expanded screening questionnaire, the RLS-EXP...
Survival among U.S. women with invasive epithelial ovarian cancerValerie McGuire
Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California 94305 5405, USA
Gynecol Oncol 84:399-403. 2002..S. women of different race/ethnicities. To investigate this issue, we evaluated pathological characteristics and death rates due to invasive epithelial ovarian cancer in a population-based sample of patients from six racial/ethnic groups...
Observational studies and randomized trials of hormone replacement therapy: what can we learn from them?Alice S Whittemore
Department of Health Research and Policy, Stanford University School of Medicine, CA 94305, USA
Epidemiology 14:8-10. 2003
Common variants in mismatch repair genes and risk of invasive ovarian cancerHonglin Song
CR UK Department of Oncology, University of Cambridge Strangeways Research Laboratory, Cambridge, UK
Carcinogenesis 27:2235-42. 2006..The observed association of PMS2 rs7797466 with ovarian cancer warrants confirmation in an independent study...
The effects of BRCA1 missense variants V1804D and M1628T on transcriptional activityKimberly Laskie Ostrow
Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Cancer Genet Cytogenet 153:177-80. 2004..M1628T had the same transcriptional activity as wild-type BRCA1 but V1804D and the empty vector control showed a 60% reduction. This indicates that V1804D is deleterious but M1628T is not...
Consortium analysis of 7 candidate SNPs for ovarian cancerSusan J Ramus
Translational Research Laboratory, University College London EGA Institute for Women s Health, London, United Kingdom
Int J Cancer 123:380-8. 2008..These null results for SNPs identified from relatively large initial studies shows the importance of replicating associations by a consortium approach...
Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: the GENEVA study. Rationale, study design and demographic characteristicsSilke Schmidt
Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA
Neuroepidemiology 30:191-204. 2008....
Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survivalHonglin Song
CR UK Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, United Kingdom
Clin Cancer Res 14:1090-5. 2008..Of particular interest are genes involved in cell cycle pathways, which regulate cell division and could plausibly influence clinical characteristics of multiple tumors types...
Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: results from two Australian studies and an additional validation setJonathan Beesley
Queensland Institute of Medical Research, Herston, Queensland, Australia
Cancer Epidemiol Biomarkers Prev 16:2557-65. 2007..Further analyses of SNPs in this gene are therefore warranted to determine whether SRD5A2 plays a role in ovarian cancer predisposition...
STK15 polymorphisms and association with risk of invasive ovarian cancerRichard A Dicioccio
Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Cancer Epidemiol Biomarkers Prev 13:1589-94. 2004..These results suggest a model of dominant inheritance of ovarian cancer risk by the I31 allele of F31I and that the I31 allele may be a common ovarian cancer susceptibility allele of low penetrance...
Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancerSimon A Gayther
Translational Research Laboratories, University College London, London, United Kingdom
Cancer Res 67:3027-35. 2007..This study highlights the need for multicenter collaborations for genetic association studies...
Common variants in RB1 gene and risk of invasive ovarian cancerHonglin Song
Cancer Research UK Department of Oncology, Strangeways Research Laboratory, University of Cambridge, Cambridge, United Kingdom
Cancer Res 66:10220-6. 2006..The possible associations of rs2854344 and rs4151620 with ovarian cancer risk warrant confirmation in independent case-control studies before studies on their biological mode of action...
BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50Robert W Haile
Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, MS 9175, Los Angeles, CA 90089 9175, USA
Cancer Epidemiol Biomarkers Prev 15:1863-70. 2006..Understanding the effect of oral contraceptives on risk of breast cancer in BRCA1 or BRCA2 mutation carriers is important because oral contraceptive use is a common, modifiable practice...
The effects of common genetic variants in oncogenes on ovarian cancer survivalLydia Quaye
Gynaecological Cancer Research Laboratory, UCL EGA Institute for Women s Health, University College London, London, United Kingdom
Clin Cancer Res 14:5833-9. 2008..The aim of this study was to evaluate associations between common germline genetic variants in the oncogenes BRAF, ERBB2, KRAS, NMI, and PIK3CA, and survival after a diagnosis of epithelial ovarian cancer...
Analysis of the human progesterone receptor gene polymorphism PROGINS in Austrian ovarian cancer patientsAlice S Whittemore
Int J Cancer 101:202; author reply 203. 2002
