Patricia L Marion
Affiliation: Stanford University
- Potent efficacy of entecavir (BMS-200475) in a duck model of hepatitis B virus replicationPatricia L Marion
Division of Gastroenterology, Stanford University School of Medicine, Stanford, California 94305 5187, USA
Antimicrob Agents Chemother 46:82-8. 2002..ETV and 3TC were both well tolerated in all treated animals. These results show that ETV is a highly potent and effective antiviral in the DHBV duck model...
- In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virusBruno B Bordier
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, California 94305, USA
J Clin Invest 112:407-14. 2003..These results provide the first preclinical data supporting the in vivo efficacy of prenylation inhibition as a novel antiviral therapy with potential application to HDV and a wide variety of other viruses...
- Inhibition of hepatitis B virus in mice by RNA interferenceAnton P McCaffrey
Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Room G305, Stanford, California, USA
Nat Biotechnol 21:639-44. 2003..Thus, RNAi effectively inhibited replication initiation in cultured cells and mammalian liver, showing that such an approach could be useful in the treatment of viral diseases...
- A prenylation inhibitor prevents production of infectious hepatitis delta virus particlesBruno B Bordier
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 269 Campus Drive, Palo Alto, CA 94305-5187, USA
J Virol 76:10465-72. 2002..Farnesyltransferase inhibitors thus represent an attractive potential class of novel antiviral agents for use against HDV, including the genotypes associated with most severe disease...
- Entecavir therapy combined with DNA vaccination for persistent duck hepatitis B virus infectionWendy K Foster
School of Molecular and Biomedical Science, University of Adelaide, Adelaide, South Australia 5005, Australia
Antimicrob Agents Chemother 47:2624-35. 2003....
- Exploring gene-deleted adenoviral vectors for delivery of short hairpin RNAs and reduction of hepatitis B virus infection in miceChristina Rauschhuber
Max von Pettenkofer Institute, Department of Virology, Ludwig Maximilians Universitat Munchen, Munich, Germany
J Gene Med 10:878-89. 2008..2, which was demonstrated to result in post-transcriptional knock-down of HBV transcripts...