Research Topics
| Patricia L MarionSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Potent efficacy of entecavir (BMS-200475) in a duck model of hepatitis B virus replicationPatricia L Marion
Division of Gastroenterology, Stanford University School of Medicine, Stanford, California 94305 5187, USA
Antimicrob Agents Chemother 46:82-8. 2002..ETV and 3TC were both well tolerated in all treated animals. These results show that ETV is a highly potent and effective antiviral in the DHBV duck model...
In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virusBruno B Bordier
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, California 94305, USA
J Clin Invest 112:407-14. 2003..These results provide the first preclinical data supporting the in vivo efficacy of prenylation inhibition as a novel antiviral therapy with potential application to HDV and a wide variety of other viruses...
Inhibition of hepatitis B virus in mice by RNA interferenceAnton P McCaffrey
Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Room G305, Stanford, California, USA
Nat Biotechnol 21:639-44. 2003..Thus, RNAi effectively inhibited replication initiation in cultured cells and mammalian liver, showing that such an approach could be useful in the treatment of viral diseases...
A prenylation inhibitor prevents production of infectious hepatitis delta virus particlesBruno B Bordier
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 269 Campus Drive, Palo Alto, CA 94305-5187, USA
J Virol 76:10465-72. 2002..Farnesyltransferase inhibitors thus represent an attractive potential class of novel antiviral agents for use against HDV, including the genotypes associated with most severe disease...
Entecavir therapy combined with DNA vaccination for persistent duck hepatitis B virus infectionWendy K Foster
School of Molecular and Biomedical Science, University of Adelaide, Adelaide, South Australia 5005, Australia
Antimicrob Agents Chemother 47:2624-35. 2003....
Exploring gene-deleted adenoviral vectors for delivery of short hairpin RNAs and reduction of hepatitis B virus infection in miceChristina Rauschhuber
Max von Pettenkofer Institute, Department of Virology, Ludwig Maximilians Universitat Munchen, Munich, Germany
J Gene Med 10:878-89. 2008..2, which was demonstrated to result in post-transcriptional knock-down of HBV transcripts...
