MATT MARINKOVICH

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation
    Mindy C DeRouen
    Cancer Biology Graduate Program, 251 Campus Drive, MSOB X234, Stanford, CA 94305 5173, USA
    BMC Dev Biol 10:112. 2010
  2. ncbi request reprint Tumour microenvironment: laminin 332 in squamous-cell carcinoma
    M Peter Marinkovich
    VA Medical Center, Palo Alto, California, USA
    Nat Rev Cancer 7:370-80. 2007
  3. ncbi request reprint Update on inherited bullous dermatoses
    M P Marinkovich
    Blistering Disease Clinic, Stanford University School of Medicine, California, USA
    Dermatol Clin 17:473-85, vii. 1999
  4. ncbi request reprint A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation
    Elizabeth A Waterman
    Dermatology Service, Palo Alto VAHCS, Palo Alto, California 94305, USA
    Cancer Res 67:4264-70. 2007
  5. ncbi request reprint Type VII collagen is required for Ras-driven human epidermal tumorigenesis
    Susana Ortiz-Urda
    VA Palo Alto Healthcare System, Palo Alto, CA 94304, USA
    Science 307:1773-6. 2005
  6. ncbi request reprint Mature human thymocytes migrate on laminin-5 with activation of metalloproteinase-14 and cleavage of CD44
    Mylène Vivinus-Nebot
    Institut National de la Sante et de la Recherche Medicale, Unité 576, Nice, France
    J Immunol 172:1397-406. 2004
  7. pmc Integrin beta4 regulates migratory behavior of keratinocytes by determining laminin-332 organization
    Bernd U Sehgal
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Biol Chem 281:35487-98. 2006
  8. ncbi request reprint Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin
    Dallas P Veitch
    Program in Epithelial Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA
    J Biol Chem 278:15661-8. 2003
  9. ncbi request reprint NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
    Maya Dajee
    Veterans Affairs Palo Alto Healthcare System and the Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 421:639-43. 2003
  10. pmc Bridging structure with function: structural, regulatory, and developmental role of laminins
    Julia Tzu
    Department of Dermatology, Program in Epithelial Biology, Stanford University, Stanford, CA 94305, USA
    Int J Biochem Cell Biol 40:199-214. 2008

Research Grants

  1. Laminins in the Skin
    MATT PETER MARINKOVICH; Fiscal Year: 2010
  2. Laminins in the Skin
    M Marinkovich; Fiscal Year: 2007
  3. ALPHA 6 BETA 4 INTEGRIN & LAMININ 5 IN CELL MIGRATION
    MATT MARINKOVICH; Fiscal Year: 2003
  4. Laminin-332 and its Receptors in Carcinoma Progression
    MATT PETER MARINKOVICH; Fiscal Year: 2010

Collaborators

  • Peter Yurchenco
  • Ismo Virtanen
  • Jeffrey H Miner
  • William G Carter
  • K Miyazaki
  • JONATHAN C contact JONES
  • E Hohenester
  • Christine E Pullar
  • Susana Ortiz-Urda
  • Ngon T Nguyen
  • Mindy C DeRouen
  • Jie Li
  • Paul A Khavari
  • Dallas P Veitch
  • Anthony E Oro
  • Julia Tzu
  • Jing Gao
  • Elizabeth A Waterman
  • Pasi Nokelainen
  • Qun Lin
  • Cheryl L Green
  • Alan J Russell
  • Douglas R Keene
  • Mark Tran
  • Kiyotoshi Sekiguchi
  • Timothy D Culp
  • Patricia Rousselle
  • Bernd U Sehgal
  • Guerrino Meneguzzi
  • Edgar F Fincher
  • Monique Aumailley
  • Clara N Dey
  • Alan Russell
  • Ngon E Nguyen
  • Yi Chen
  • Mylène Vivinus-Nebot
  • Jack L Arbiser
  • Valerie M Weaver
  • Maya Dajee
  • Nastaran Zahir
  • Hanson Zhen
  • Samantha Williams
  • Si Hui Tan
  • Hiroyuki Ido
  • Kenji Harada
  • Michael Nguyen
  • Bruce A Morgan
  • Chih Hsin Chen
  • Sruthi Tallapragada
  • Noriyasu Sakai
  • Basil A J Horst
  • Lynn R Budgeon
  • Sumio Matzno
  • Phillip J DeBiase
  • Neil D Christensen
  • Teng Leong Chew
  • Jessica N Claiborne
  • Marvin A Karasek
  • Susan B Hopkinson
  • Hoang T Tran
  • Lisa Zhou
  • Hyangkyu Lee
  • George R Martin
  • Yoshihiko Yamada
  • Ulrike Mayer
  • Jan F Talts
  • Leena Bruckner-Tuderman
  • Joshua R Sanes
  • Klaus von der Mark
  • Mats Paulsson
  • Karl Tryggvason
  • Hynda K Kleinman
  • Takako Sasaki
  • Eva Engvall
  • Jurgen Engel
  • Peter Ekblom
  • Jouni Uitto
  • Ulla M Wewer
  • Lynn Y Sakai
  • Manuel Patarroyo
  • Vito Quaranta
  • Lei Chen
  • Rainer Deutzmann
  • David Edgar
  • Lydia M Sorokin
  • John Garcia
  • Beth O Van Emburgh
  • Mark Steven Miller
  • Jean Philippe Breittmayer
  • Xiaobo Su

Detail Information

Publications21

  1. pmc Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation
    Mindy C DeRouen
    Cancer Biology Graduate Program, 251 Campus Drive, MSOB X234, Stanford, CA 94305 5173, USA
    BMC Dev Biol 10:112. 2010
    ..Previous reports have implicated laminins in hair follicle epithelial invagination...
  2. ncbi request reprint Tumour microenvironment: laminin 332 in squamous-cell carcinoma
    M Peter Marinkovich
    VA Medical Center, Palo Alto, California, USA
    Nat Rev Cancer 7:370-80. 2007
    ..The extracellular interactions of laminin 332 appear amenable to antibody-mediated therapies...
  3. ncbi request reprint Update on inherited bullous dermatoses
    M P Marinkovich
    Blistering Disease Clinic, Stanford University School of Medicine, California, USA
    Dermatol Clin 17:473-85, vii. 1999
    ..This review focuses on the progress which has been achieved in inherited bullous dermatoses...
  4. ncbi request reprint A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation
    Elizabeth A Waterman
    Dermatology Service, Palo Alto VAHCS, Palo Alto, California 94305, USA
    Cancer Res 67:4264-70. 2007
    ..This uncoupling of stable adhesion from tumor progression in our studies suggests that laminin-332/collagen VII interaction promotes epidermal carcinogenesis through signaling rather than adhesion...
  5. ncbi request reprint Type VII collagen is required for Ras-driven human epidermal tumorigenesis
    Susana Ortiz-Urda
    VA Palo Alto Healthcare System, Palo Alto, CA 94304, USA
    Science 307:1773-6. 2005
    ..Tumor-stroma interactions mediated by collagen VII thus promote neoplasia, and retention of NC1 sequences in a subset of RDEB patients may contribute to their increased susceptibility to squamous cell carcinoma...
  6. ncbi request reprint Mature human thymocytes migrate on laminin-5 with activation of metalloproteinase-14 and cleavage of CD44
    Mylène Vivinus-Nebot
    Institut National de la Sante et de la Recherche Medicale, Unité 576, Nice, France
    J Immunol 172:1397-406. 2004
    ..These data suggest that, in vivo, laminin-5 may function in the migration of mature thymocytes within the medulla and be part of the thymic emigration process...
  7. pmc Integrin beta4 regulates migratory behavior of keratinocytes by determining laminin-332 organization
    Bernd U Sehgal
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Biol Chem 281:35487-98. 2006
    ....
  8. ncbi request reprint Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin
    Dallas P Veitch
    Program in Epithelial Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA
    J Biol Chem 278:15661-8. 2003
    ..In addition, mTLD/BMP-1 null mice were shown to have deficient laminin-5 processing. Together, these data identify laminin-5 as a substrate for mTLD, suggesting a role for laminin-5 processing by mTLD in the skin...
  9. ncbi request reprint NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
    Maya Dajee
    Veterans Affairs Palo Alto Healthcare System and the Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 421:639-43. 2003
    ..Human cell tumorigenesis is dependent on laminin 5 and alpha6beta4 integrin. Thus, IkappaBalpha circumvents restraints on growth promotion induced by oncogenic Ras and can act with Ras to induce invasive human tissue neoplasia...
  10. pmc Bridging structure with function: structural, regulatory, and developmental role of laminins
    Julia Tzu
    Department of Dermatology, Program in Epithelial Biology, Stanford University, Stanford, CA 94305, USA
    Int J Biochem Cell Biol 40:199-214. 2008
    ..In this review, we will define how laminin structure complements function and explore its role in both normal and pathologic processes...
  11. doi request reprint Targeting a tumor-specific laminin domain critical for human carcinogenesis
    Mark Tran
    Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Cancer Res 68:2885-94. 2008
    ..These results show a remarkable selectivity of expression and function for laminin-332 G45 in human SCC tumorigenesis and implicate it as a specific target for anticancer therapy...
  12. pmc Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis
    Jing Gao
    Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA
    Genes Dev 22:2111-24. 2008
    ..These studies show that epithelial-derived laminin-511 is a critical early signal that directs ciliary function and DP maintenance as a requirement for hair follicle downgrowth...
  13. pmc Keratinocyte-secreted laminin 5 can function as a transient receptor for human papillomaviruses by binding virions and transferring them to adjacent cells
    Timothy D Culp
    The Jake Gittlen Cancer Research Foundation, Milton S Hershey Medical Center, Pennsylvania State University, 500 University Drive, Hershey, PA 17033 2390, USA
    J Virol 80:8940-50. 2006
    ....
  14. pmc beta4 integrin and epidermal growth factor coordinately regulate electric field-mediated directional migration via Rac1
    Christine E Pullar
    Department of Dermatology, University of California, Davis, Davis, CA 95616, USA
    Mol Biol Cell 17:4925-35. 2006
    ....
  15. pmc Overexpression of laminin-8 in human dermal microvascular endothelial cells promotes angiogenesis-related functions
    Jie Li
    Dermatology Service, Palo Alto VA Health Care System, Stanford University School of Medicine, Stanford, California 94305, USA
    J Invest Dermatol 126:432-40. 2006
    ..These studies suggest that laminin-8 overexpression may prove to be a useful method to engineer HDMECs to promote angiogenesis and wound repair...
  16. pmc Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue
    Susana Ortiz-Urda
    Veterans Affairs Palo Alto Healthcare System, Palo Alto, California, USA
    J Clin Invest 111:251-5. 2003
    ..This article was published online in advance of the print edition. The date of publication is available from the JCI website, http://www.jci.org...
  17. ncbi request reprint Involvement of p53 and p16 tumor suppressor genes in recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma
    Jack L Arbiser
    Department of Dermatology, Emory University School of Medicine and Atlanta VA Medical Center, Atlanta, Georgia 30322, USA
    J Invest Dermatol 123:788-90. 2004
    ..This is the first description of specific abnormalities in tumor suppressor genes in RDEB associated SCC, and demonstrates that alterations in both p53 and p16ink4a can contribute to RDEB associated SCC...
  18. pmc Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors
    Nastaran Zahir
    Department of Pathology and Laboratory Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cell Biol 163:1397-407. 2003
    ..Therefore, epithelial tumors could survive in the absence of exogenous basement membrane through autocrine LM-5-alpha6beta4 integrin-RAC-NFkappaB signaling...
  19. ncbi request reprint Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin
    Alan J Russell
    Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Cell Sci 116:3543-56. 2003
    ....
  20. pmc Laminin-10 is crucial for hair morphogenesis
    Jie Li
    Program in Epithelial Biology, Stanford University School of Medicine, 269 Campus Drive, Room 2145, CA 94305, USA
    EMBO J 22:2400-10. 2003
    ..We conclude that laminin-10 is required for hair follicle development and report the first use of exogenous protein to correct a cutaneous developmental defect...
  21. ncbi request reprint A simplified laminin nomenclature
    Monique Aumailley
    Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany
    Matrix Biol 24:326-32. 2005
    ..The chain origin of a domain is specified by the chain nomenclature, such as alpha1L4a. The abbreviation LM is suggested for laminin. Otherwise, the nomenclature remains unaltered...

Research Grants14

  1. Laminins in the Skin
    MATT PETER MARINKOVICH; Fiscal Year: 2010
    ..The studies proposed in the second Aim will determine the cellular and molecular interactions, as well as the triggering factors which precipitate epidermal proliferation and immune infiltration in this model. ..
  2. Laminins in the Skin
    M Marinkovich; Fiscal Year: 2007
    ..We also seek to characterize the interactions between the laminin beta3 short arm with its putative ligands, type VII collagen and laminin-6, and examine its role in dermal-epidermal cohesion and carcinoma development. ..
  3. ALPHA 6 BETA 4 INTEGRIN & LAMININ 5 IN CELL MIGRATION
    MATT MARINKOVICH; Fiscal Year: 2003
    ....
  4. Laminin-332 and its Receptors in Carcinoma Progression
    MATT PETER MARINKOVICH; Fiscal Year: 2010
    ..This proposal also seeks to develop novel and specific molecular therapies to inhibit the function of laminin-332 and associated molecules in SCC without disrupting normal skin tissue. ..