Affiliation: Stanford University
- Future Directions for Pain Management: Lessons from the Institute of Medicine Pain Report and the National Pain StrategySean Mackey
Departments of Anesthesiology, Perioperative and Pain Medicine, Neurosciences and Neurology, Stanford University School of Medicine, Palo Alto, CA 94304, USA Electronic address
Hand Clin 32:91-8. 2016..For precision pain medicine to be successful, we need to link learning health systems with pain biomarkers (eg, genomics, proteomics, patient reported outcomes, brain markers) and its treatment. ..
- Functional imaging and the neural systems of chronic painSean C Mackey
Division of Pain Management, Department of Anesthesia, Stanford University Medical Center, Palo Alto, CA 94305, USA
Neurosurg Clin N Am 15:269-88. 2004..It is opening windows into the function of the brain that were previously closed...
- Pharmacologic therapies for complex regional pain syndromeSean Mackey
Stanford University, 780 Welch Road 208, Palo Alto, CA 94304, USA
Curr Pain Headache Rep 11:38-43. 2007..These agents should be used in conjunction with a comprehensive interdisciplinary approach aimed at functional restoration and improved quality of life...
- Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levelsJarred Younger
Stanford University School of Medicine, Palo Alto, California 94304 1573, USA
Arthritis Rheum 65:529-38. 2013..Secondary outcomes included general satisfaction with life, positive mood, sleep quality, and fatigue...
- Towards a physiology-based measure of pain: patterns of human brain activity distinguish painful from non-painful thermal stimulationJUSTIN E BROWN
Department of Anesthesia, Stanford University, Palo Alto, California, United States of America
PLoS ONE 6:e24124. 2011..Our findings demonstrate that fMRI with SVM learning can assess pain without requiring any communication from the person being tested. We outline tasks that should be completed to advance this approach toward use in clinical settings...
- Perioperative interventions to reduce chronic postsurgical painIan Carroll
Department of Anesthesiology, Division of Pain Management, Stanford School of Medicine, Palo Alto, CA, USA
J Reconstr Microsurg 29:213-22. 2013..The surgeon, working with the anesthesiologist, has the ability to modify both early and chronic postoperative pain by implementing an evidence-based preventative analgesia plan...
- Sensory pain qualities in neuropathic painSean Mackey
Department of Anesthesia, Division of Pain Management, Stanford University School of Medicine, Stanford, California, USA
J Pain 13:58-63. 2012..Results of the confirmatory factor analysis strongly supported the correlated 2-factor model...
- Reduced cold pain tolerance in chronic pain patients following opioid detoxificationJarred Younger
Stanford University School of Medicine, Department of Anesthesia, Division of Pain Management, Palo Alto, California 94304 1573, USA
Pain Med 9:1158-63. 2008..Little scientific attention has been given to how cessation of opioid medication affects the hyperalgesic state. In this study, we examined the effects of opioid tapering on pain sensitivity in chronic pain patients...
- Pulsed radiofrequency for the treatment of chronic ilioinguinal neuropathyRaj Mitra
Stanford University Interventional Spine Center, 300 Pasteur Dr, Edwards Building, Rm R105B, Stanford, CA 94305, USA
Hernia 11:369-71. 2007..Long-term results of non-surgical interventions are fair at best. We present a case of chronic ilioinguinal neuropathy treated with pulsed radiofrequency...
- Sympathetic block with botulinum toxin to treat complex regional pain syndromeIan Carroll
Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA 94304 1573, USA
Ann Neurol 65:348-51. 2009..02). BTA profoundly prolonged the analgesia from sympathetic block in this preliminary study...
- Chronic myofascial temporomandibular pain is associated with neural abnormalities in the trigeminal and limbic systemsJarred W Younger
Stanford University School of Medicine, Department of Anesthesia, Division of Pain Management, 780 Welch Rd, Suite 208E, Palo Alto, CA 94304, USA
Pain 149:222-8. 2010..The pattern of gray matter abnormality found in M-TMD individuals suggests the involvement of trigeminal and limbic system dysregulation, as well as potential somatotopic reorganization in the putamen, thalamus, and somatosensory cortex...
- Pain quality predicts lidocaine analgesia among patients with suspected neuropathic painIan R Carroll
Stanford University School of Medicine, 780 Welch Rd Suite 208E, Palo Alto, CA 94040, USA
Pain Med 11:617-21. 2010..We hypothesized that differing baseline pain qualities (e.g. "stabbing" vs "dull") might define specific subgroups responsive to intravenous (IV) lidocaine-a potent sodium channel blocker...
- MR guidance of sympathetic nerve blockade: measurement of vasomotor response initial experience in seven patientsDaniel Y Sze
Division of Cardiovascular and Interventional Radiology, Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr, Stanford, CA 94305, USA
Radiology 223:574-80. 2002..MR imaging can provide both procedural imaging guidance and measurement of efficacy for sympathetic nerve blocks...
- Mexiletine therapy for chronic pain: survival analysis identifies factors predicting clinical successIan R Carroll
Stanford Pain Management Center, Stanford University Medical Center, Palo Alto, CA 94304 1573, USA
J Pain Symptom Manage 35:321-6. 2008..Test infusions with lidocaine identify patients most likely to continue mexiletine therapy. Further work is needed to confirm these results and evaluate the relative acceptance of mexiletine vs. other treatments of neuropathic pain...
- Pain outcomes: a brief review of instruments and techniquesJarred Younger
Department of Anesthesia, Division of Pain Management, Stanford University School of Medicine, 780 Welch Road, Suite 208C, Palo Alto, CA 94304 1573, USA
Curr Pain Headache Rep 13:39-43. 2009..By selecting the proper tools and employing them correctly, we can obtain highly reliable and valid measures of pain outcomes in research and clinical care...
- Human response to unintended intrathecal injection of botulinum toxinIan Carroll
Division of Pain Management, Department of Anesthesiology, Stanford University, Palo Alto, CA 94040, USA
Pain Med 12:1094-7. 2011..Describe the first reported human intrathecal (IT) botulinum toxin injection...
- Preoccupation in an early-romantic relationship predicts experimental pain reliefAneesha Nilakantan
Department of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Palo Alto, California
Pain Med 15:947-53. 2014..We hypothesized that a greater degree of preoccupation in the early stages of a romantic relationship would be associated with greater analgesia during a pain induction task...
- Viewing pictures of a romantic partner reduces experimental pain: involvement of neural reward systemsJarred Younger
Department of Anesthesia, Stanford University School of Medicine, Stanford, California, United States of America
PLoS ONE 5:e13309. 2010..The results suggest that the activation of neural reward systems via non-pharmacologic means can reduce the experience of pain...
- Complex regional pain syndrome is associated with structural abnormalities in pain-related regions of the human brainMeredith J Barad
Stanford University School of Medicine, Stanford University, Palo Alto, California
J Pain 15:197-203. 2014..Our findings demonstrate that CRPS is associated with abnormal brain system morphology, particularly pain-related sensory, affect, motor, and autonomic systems...
- Functional magnetic resonance imaging identifies somatotopic organization of nociception in the human spinal cordPaul Nash
Department of Anesthesiology, Division of Pain Medicine, Stanford University Medical Center, Stanford, CA, USA
Pain 154:776-81. 2013..Our study contributes to creating an objective analysis of pain transmission; other investigators can use these results to further study central nervous system changes that occur in patients with acute and chronic pain...
- Test-retest reliability of thermal temporal summation using an individualized protocolJiang Ti Kong
Department of Anesthesia, Division of Pain Medicine, Stanford Neuroscience and Pain Laboratory, Stanford University, Palo Alto, California 94304, USA
J Pain 14:79-88. 2013..Finally, a Bland-Altman analysis suggested that TS is reliable across the range of observed scores. Without intervention, thermally-generated TS is generally stable within day and between days...
- Understanding central mechanisms of acupuncture analgesia using dynamic quantitative sensory testing: a reviewJiang Ti Kong
Stanford Systems Neuroscience and Pain Laboratory, Department of Anesthesiology, Division of Pain Medicine, School of Medicine, Stanford University, 1070 Arastradero Road, Suite 200, Palo Alto, CA 94304, USA
Evid Based Complement Alternat Med 2013:187182. 2013..The appropriate addition of TS and CPM to our current research armamentarium will facilitate our efforts to elucidate the central analgesic mechanisms of acupuncture in clinical populations...
- Development of the Stanford Expectations of Treatment Scale (SETS): a tool for measuring patient outcome expectancy in clinical trialsJarred Younger
Department of Anesthesia, Stanford University School of Medicine, CA 94304, USA
Clin Trials 9:767-76. 2012..There is therefore a need for a tool that prospectively predicts expectancy effects on treatment outcomes across a wide range of treatment modalities...
- Real-time fMRI applied to pain managementHeather Chapin
Department of Anesthesia, Stanford University, Palo Alto, CA, United States
Neurosci Lett 520:174-81. 2012..Finally, remaining methodological questions concerning the further development of rtfMRI feedback and its implications for the future of pain research are also discussed...
- Pulsed radiofrequency for chronic painDavid Byrd
Stanford University, 780 Welch Road 208, Palo Alto, CA 94304, USA
Curr Pain Headache Rep 12:37-41. 2008..Although much anecdotal evidence exists in favor of PRF, there are few quality studies substantiating its utility...
- Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot studyJarred Younger
School of Medicine, Department of Anesthesia, Division of Pain Management, Stanford University, 780 Welch Road, Suite 208, Palo Alto, CA 94304 1573, USA
Pain Med 10:663-72. 2009..In this pilot clinical trial, we tested the effectiveness of low-dose naltrexone in treating the symptoms of fibromyalgia...
- Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network studyEpifanio Bagarinao
Department of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University Medical Center, Stanford, CA, USA
Pain 155:2502-9. 2014....
- Self-loathing aspects of depression reduce postoperative opioid cessation rateJennifer M Hah
Division of Pain Medicine, Stanford University, Palo Alto, California, USA
Pain Med 15:954-64. 2014..We aimed to identify the underlying factors of the BDI-II (affective/cognitive vs somatic) associated with a decreased rate of opioid cessation after surgery...
- Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesiaIan Carroll
Division of Pain Management, Department of Anesthesia, Stanford University Medical Center, Palo Alto, CA 94304 1573, USA
Clin J Pain 23:702-6. 2007....
- A novel CT-guided transpsoas approach to diagnostic genitofemoral nerve block and ablationDavid Parris
Department of Anesthesiology and Pain Management, Stanford University Medical Center, Stanford, California 94304, USA
Pain Med 11:785-9. 2010..We report a computed tomography (CT)-guided transpsoas technique to selectively block the genitofemoral nerve for both diagnostic and therapeutic purposes while avoiding injury to the nearby ureter and intestines...
- Healthy young women with serotonin transporter SS polymorphism show a pro-inflammatory bias under resting and stress conditionsCarolyn A Fredericks
Department of Psychology, Stanford University, Stanford, CA 94305, USA
Brain Behav Immun 24:350-7. 2010....
- Role of neuroimaging in analgesic drug developmentJane Lawrence
Department of Anesthesia, Stanford University, Stanford, California 94304, USA
Drugs R D 9:323-34. 2008..In the future, neuroimaging will certainly impact the methodology of analgesic drug development as it may lead to quicker and more efficient methods of evaluating the neural modulation of chronic pain...
- Continuous peripheral nerve blocksRichard C Shinaman
Stanford University School of Medicine, Division of Pain Management, 780 Welch Road, Suite F, Palo Alto, CA 94304 1573, USA
Curr Pain Headache Rep 9:24-9. 2005..The consistent recognition that these techniques dramatically increase patient satisfaction should dictate an increasing presence in the field of pain management throughout the next several years...
- Control over brain activation and pain learned by using real-time functional MRIR Christopher deCharms
Omneuron, Inc, 99 El Camino Real, Menlo Park, CA 94025, USA
Proc Natl Acad Sci U S A 102:18626-31. 2005....
- Neural correlates of individual differences in pain-related fear and anxietyKevin N Ochsner
Department of Psychology, Columbia University, Schermerhorn Hall, New York, NY 10027, USA
Pain 120:69-77. 2006..The present findings may help clarify both the impact of individual differences in emotion on the neural correlates of pain, and the roles in anxiety, fear, and pain processing played by medial and orbitofrontal systems...
- fMRI of Pain in the Human Spinal CordSean C Mackey; Fiscal Year: 2010..Furthermore, we will have a more objective means of assessing neural function in patients with peripheral nerve and spinal cord injury. ..