Sean Mackey

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Pharmacologic therapies for complex regional pain syndrome
    Sean Mackey
    Stanford University, 780 Welch Road 208, Palo Alto, CA 94304, USA
    Curr Pain Headache Rep 11:38-43. 2007
  2. ncbi request reprint Functional imaging and the neural systems of chronic pain
    Sean C Mackey
    Division of Pain Management, Department of Anesthesia, Stanford University Medical Center, Palo Alto, CA 94305, USA
    Neurosurg Clin N Am 15:269-88. 2004
  3. doi request reprint Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels
    Jarred Younger
    Stanford University School of Medicine, Palo Alto, California 94304 1573, USA
    Arthritis Rheum 65:529-38. 2013
  4. doi request reprint Perioperative interventions to reduce chronic postsurgical pain
    Ian Carroll
    Department of Anesthesiology, Division of Pain Management, Stanford School of Medicine, Palo Alto, CA, USA
    J Reconstr Microsurg 29:213-22. 2013
  5. pmc Sensory pain qualities in neuropathic pain
    Sean Mackey
    Department of Anesthesia, Division of Pain Management, Stanford University School of Medicine, Stanford, California, USA
    J Pain 13:58-63. 2012
  6. pmc Towards a physiology-based measure of pain: patterns of human brain activity distinguish painful from non-painful thermal stimulation
    JUSTIN E BROWN
    Department of Anesthesia, Stanford University, Palo Alto, California, United States of America
    PLoS ONE 6:e24124. 2011
  7. pmc Reduced cold pain tolerance in chronic pain patients following opioid detoxification
    Jarred Younger
    Stanford University School of Medicine, Department of Anesthesia, Division of Pain Management, Palo Alto, California 94304 1573, USA
    Pain Med 9:1158-63. 2008
  8. pmc Pulsed radiofrequency for the treatment of chronic ilioinguinal neuropathy
    Raj Mitra
    Stanford University Interventional Spine Center, 300 Pasteur Dr, Edwards Building, Rm R105B, Stanford, CA 94305, USA
    Hernia 11:369-71. 2007
  9. pmc Sympathetic block with botulinum toxin to treat complex regional pain syndrome
    Ian Carroll
    Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA 94304 1573, USA
    Ann Neurol 65:348-51. 2009
  10. pmc Chronic myofascial temporomandibular pain is associated with neural abnormalities in the trigeminal and limbic systems
    Jarred W Younger
    Stanford University School of Medicine, Department of Anesthesia, Division of Pain Management, 780 Welch Rd, Suite 208E, Palo Alto, CA 94304, USA
    Pain 149:222-8. 2010

Research Grants

  1. fMRI of Pain in the Human Spinal Cord
    Sean Mackey; Fiscal Year: 2006
  2. fMRI of Pain in the Human Spinal Cord
    Sean Mackey; Fiscal Year: 2007
  3. fMRI of Pain in the Human Spinal Cord
    Sean Mackey; Fiscal Year: 2009
  4. fMRI of Pain in the Human Spinal Cord
    Sean C Mackey; Fiscal Year: 2010

Collaborators

Detail Information

Publications31

  1. pmc Pharmacologic therapies for complex regional pain syndrome
    Sean Mackey
    Stanford University, 780 Welch Road 208, Palo Alto, CA 94304, USA
    Curr Pain Headache Rep 11:38-43. 2007
    ..These agents should be used in conjunction with a comprehensive interdisciplinary approach aimed at functional restoration and improved quality of life...
  2. ncbi request reprint Functional imaging and the neural systems of chronic pain
    Sean C Mackey
    Division of Pain Management, Department of Anesthesia, Stanford University Medical Center, Palo Alto, CA 94305, USA
    Neurosurg Clin N Am 15:269-88. 2004
    ..It is opening windows into the function of the brain that were previously closed...
  3. doi request reprint Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels
    Jarred Younger
    Stanford University School of Medicine, Palo Alto, California 94304 1573, USA
    Arthritis Rheum 65:529-38. 2013
    ..Secondary outcomes included general satisfaction with life, positive mood, sleep quality, and fatigue...
  4. doi request reprint Perioperative interventions to reduce chronic postsurgical pain
    Ian Carroll
    Department of Anesthesiology, Division of Pain Management, Stanford School of Medicine, Palo Alto, CA, USA
    J Reconstr Microsurg 29:213-22. 2013
    ..The surgeon, working with the anesthesiologist, has the ability to modify both early and chronic postoperative pain by implementing an evidence-based preventative analgesia plan...
  5. pmc Sensory pain qualities in neuropathic pain
    Sean Mackey
    Department of Anesthesia, Division of Pain Management, Stanford University School of Medicine, Stanford, California, USA
    J Pain 13:58-63. 2012
    ..Results of the confirmatory factor analysis strongly supported the correlated 2-factor model...
  6. pmc Towards a physiology-based measure of pain: patterns of human brain activity distinguish painful from non-painful thermal stimulation
    JUSTIN E BROWN
    Department of Anesthesia, Stanford University, Palo Alto, California, United States of America
    PLoS ONE 6:e24124. 2011
    ..Our findings demonstrate that fMRI with SVM learning can assess pain without requiring any communication from the person being tested. We outline tasks that should be completed to advance this approach toward use in clinical settings...
  7. pmc Reduced cold pain tolerance in chronic pain patients following opioid detoxification
    Jarred Younger
    Stanford University School of Medicine, Department of Anesthesia, Division of Pain Management, Palo Alto, California 94304 1573, USA
    Pain Med 9:1158-63. 2008
    ..Little scientific attention has been given to how cessation of opioid medication affects the hyperalgesic state. In this study, we examined the effects of opioid tapering on pain sensitivity in chronic pain patients...
  8. pmc Pulsed radiofrequency for the treatment of chronic ilioinguinal neuropathy
    Raj Mitra
    Stanford University Interventional Spine Center, 300 Pasteur Dr, Edwards Building, Rm R105B, Stanford, CA 94305, USA
    Hernia 11:369-71. 2007
    ..Long-term results of non-surgical interventions are fair at best. We present a case of chronic ilioinguinal neuropathy treated with pulsed radiofrequency...
  9. pmc Sympathetic block with botulinum toxin to treat complex regional pain syndrome
    Ian Carroll
    Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA 94304 1573, USA
    Ann Neurol 65:348-51. 2009
    ..02). BTA profoundly prolonged the analgesia from sympathetic block in this preliminary study...
  10. pmc Chronic myofascial temporomandibular pain is associated with neural abnormalities in the trigeminal and limbic systems
    Jarred W Younger
    Stanford University School of Medicine, Department of Anesthesia, Division of Pain Management, 780 Welch Rd, Suite 208E, Palo Alto, CA 94304, USA
    Pain 149:222-8. 2010
    ..The pattern of gray matter abnormality found in M-TMD individuals suggests the involvement of trigeminal and limbic system dysregulation, as well as potential somatotopic reorganization in the putamen, thalamus, and somatosensory cortex...
  11. pmc Pain quality predicts lidocaine analgesia among patients with suspected neuropathic pain
    Ian R Carroll
    Stanford University School of Medicine, 780 Welch Rd Suite 208E, Palo Alto, CA 94040, USA
    Pain Med 11:617-21. 2010
    ..We hypothesized that differing baseline pain qualities (e.g. "stabbing" vs "dull") might define specific subgroups responsive to intravenous (IV) lidocaine-a potent sodium channel blocker...
  12. ncbi request reprint MR guidance of sympathetic nerve blockade: measurement of vasomotor response initial experience in seven patients
    Daniel Y Sze
    Division of Cardiovascular and Interventional Radiology, Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr, Stanford, CA 94305, USA
    Radiology 223:574-80. 2002
    ..MR imaging can provide both procedural imaging guidance and measurement of efficacy for sympathetic nerve blocks...
  13. pmc Mexiletine therapy for chronic pain: survival analysis identifies factors predicting clinical success
    Ian R Carroll
    Stanford Pain Management Center, Stanford University Medical Center, Palo Alto, CA 94304 1573, USA
    J Pain Symptom Manage 35:321-6. 2008
    ..Test infusions with lidocaine identify patients most likely to continue mexiletine therapy. Further work is needed to confirm these results and evaluate the relative acceptance of mexiletine vs. other treatments of neuropathic pain...
  14. pmc Pain outcomes: a brief review of instruments and techniques
    Jarred Younger
    Department of Anesthesia, Division of Pain Management, Stanford University School of Medicine, 780 Welch Road, Suite 208C, Palo Alto, CA 94304 1573, USA
    Curr Pain Headache Rep 13:39-43. 2009
    ..By selecting the proper tools and employing them correctly, we can obtain highly reliable and valid measures of pain outcomes in research and clinical care...
  15. doi request reprint Human response to unintended intrathecal injection of botulinum toxin
    Ian Carroll
    Division of Pain Management, Department of Anesthesiology, Stanford University, Palo Alto, CA 94040, USA
    Pain Med 12:1094-7. 2011
    ..Describe the first reported human intrathecal (IT) botulinum toxin injection...
  16. doi request reprint Complex regional pain syndrome is associated with structural abnormalities in pain-related regions of the human brain
    Meredith J Barad
    Stanford University School of Medicine, Stanford University, Palo Alto, California
    J Pain 15:197-203. 2014
    ..Our findings demonstrate that CRPS is associated with abnormal brain system morphology, particularly pain-related sensory, affect, motor, and autonomic systems...
  17. doi request reprint Functional magnetic resonance imaging identifies somatotopic organization of nociception in the human spinal cord
    Paul Nash
    Department of Anesthesiology, Division of Pain Medicine, Stanford University Medical Center, Stanford, CA, USA
    Pain 154:776-81. 2013
    ..Our study contributes to creating an objective analysis of pain transmission; other investigators can use these results to further study central nervous system changes that occur in patients with acute and chronic pain...
  18. pmc Test-retest reliability of thermal temporal summation using an individualized protocol
    Jiang Ti Kong
    Department of Anesthesia, Division of Pain Medicine, Stanford Neuroscience and Pain Laboratory, Stanford University, Palo Alto, California 94304, USA
    J Pain 14:79-88. 2013
    ..Finally, a Bland-Altman analysis suggested that TS is reliable across the range of observed scores. Without intervention, thermally-generated TS is generally stable within day and between days...
  19. doi request reprint Development of the Stanford Expectations of Treatment Scale (SETS): a tool for measuring patient outcome expectancy in clinical trials
    Jarred Younger
    Department of Anesthesia, Stanford University School of Medicine, CA 94304, USA
    Clin Trials 9:767-76. 2012
    ..There is therefore a need for a tool that prospectively predicts expectancy effects on treatment outcomes across a wide range of treatment modalities...
  20. pmc Understanding central mechanisms of acupuncture analgesia using dynamic quantitative sensory testing: a review
    Jiang Ti Kong
    Stanford Systems Neuroscience and Pain Laboratory, Department of Anesthesiology, Division of Pain Medicine, School of Medicine, Stanford University, 1070 Arastradero Road, Suite 200, Palo Alto, CA 94304, USA
    Evid Based Complement Alternat Med 2013:187182. 2013
    ..The appropriate addition of TS and CPM to our current research armamentarium will facilitate our efforts to elucidate the central analgesic mechanisms of acupuncture in clinical populations...
  21. pmc Real-time fMRI applied to pain management
    Heather Chapin
    Department of Anesthesia, Stanford University, Palo Alto, CA, United States
    Neurosci Lett 520:174-81. 2012
    ..Finally, remaining methodological questions concerning the further development of rtfMRI feedback and its implications for the future of pain research are also discussed...
  22. pmc Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot study
    Jarred Younger
    School of Medicine, Department of Anesthesia, Division of Pain Management, Stanford University, 780 Welch Road, Suite 208, Palo Alto, CA 94304 1573, USA
    Pain Med 10:663-72. 2009
    ..In this pilot clinical trial, we tested the effectiveness of low-dose naltrexone in treating the symptoms of fibromyalgia...
  23. pmc Pulsed radiofrequency for chronic pain
    David Byrd
    Stanford University, 780 Welch Road 208, Palo Alto, CA 94304, USA
    Curr Pain Headache Rep 12:37-41. 2008
    ..Although much anecdotal evidence exists in favor of PRF, there are few quality studies substantiating its utility...
  24. ncbi request reprint Self-loathing aspects of depression reduce postoperative opioid cessation rate
    Jennifer M Hah
    Division of Pain Medicine, Stanford University, Palo Alto, California, USA
    Pain Med 15:954-64. 2014
    ..We aimed to identify the underlying factors of the BDI-II (affective/cognitive vs somatic) associated with a decreased rate of opioid cessation after surgery...
  25. pmc A novel CT-guided transpsoas approach to diagnostic genitofemoral nerve block and ablation
    David Parris
    Department of Anesthesiology and Pain Management, Stanford University Medical Center, Stanford, California 94304, USA
    Pain Med 11:785-9. 2010
    ..We report a computed tomography (CT)-guided transpsoas technique to selectively block the genitofemoral nerve for both diagnostic and therapeutic purposes while avoiding injury to the nearby ureter and intestines...
  26. pmc Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia
    Ian Carroll
    Division of Pain Management, Department of Anesthesia, Stanford University Medical Center, Palo Alto, CA 94304 1573, USA
    Clin J Pain 23:702-6. 2007
    ....
  27. pmc Healthy young women with serotonin transporter SS polymorphism show a pro-inflammatory bias under resting and stress conditions
    Carolyn A Fredericks
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Brain Behav Immun 24:350-7. 2010
    ....
  28. pmc Role of neuroimaging in analgesic drug development
    Jane Lawrence
    Department of Anesthesia, Stanford University, Stanford, California 94304, USA
    Drugs R D 9:323-34. 2008
    ..In the future, neuroimaging will certainly impact the methodology of analgesic drug development as it may lead to quicker and more efficient methods of evaluating the neural modulation of chronic pain...
  29. ncbi request reprint Continuous peripheral nerve blocks
    Richard C Shinaman
    Stanford University School of Medicine, Division of Pain Management, 780 Welch Road, Suite F, Palo Alto, CA 94304 1573, USA
    Curr Pain Headache Rep 9:24-9. 2005
    ..The consistent recognition that these techniques dramatically increase patient satisfaction should dictate an increasing presence in the field of pain management throughout the next several years...
  30. pmc Neural correlates of individual differences in pain-related fear and anxiety
    Kevin N Ochsner
    Department of Psychology, Columbia University, Schermerhorn Hall, New York, NY 10027, USA
    Pain 120:69-77. 2006
    ..The present findings may help clarify both the impact of individual differences in emotion on the neural correlates of pain, and the roles in anxiety, fear, and pain processing played by medial and orbitofrontal systems...
  31. pmc Control over brain activation and pain learned by using real-time functional MRI
    R Christopher deCharms
    Omneuron, Inc, 99 El Camino Real, Menlo Park, CA 94025, USA
    Proc Natl Acad Sci U S A 102:18626-31. 2005
    ....

Research Grants5

  1. fMRI of Pain in the Human Spinal Cord
    Sean Mackey; Fiscal Year: 2006
    ..Furthermore, we will have a more objective means of assessing neural function in patients with peripheral nerve and spinal cord injury. ..
  2. fMRI of Pain in the Human Spinal Cord
    Sean Mackey; Fiscal Year: 2007
    ..Furthermore, we will have a more objective means of assessing neural function in patients with peripheral nerve and spinal cord injury. ..
  3. fMRI of Pain in the Human Spinal Cord
    Sean Mackey; Fiscal Year: 2009
    ..Furthermore, we will have a more objective means of assessing neural function in patients with peripheral nerve and spinal cord injury. ..
  4. fMRI of Pain in the Human Spinal Cord
    Sean C Mackey; Fiscal Year: 2010
    ..Furthermore, we will have a more objective means of assessing neural function in patients with peripheral nerve and spinal cord injury. ..