M P Lutolf

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
    M P Lutolf
    Integrative Biosciences Institute, Ecole Polytechnique Federale de Lausanne EPFL, Building AA B 039, CH 1015 Lausanne, Switzerland
    Nat Biotechnol 23:47-55. 2005
  2. ncbi request reprint Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs
    G P Raeber
    Institute of Bioengineering and Institute of Chemical Sciences and Engineering, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
    Acta Biomater 3:615-29. 2007
  3. pmc Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration
    G P Raeber
    Integrative Biosciences Institute and Institute for Chemical Science and Engineering, Ecole Polytechnique Federale de Lausanne EPFL, Switzerland
    Biophys J 89:1374-88. 2005
  4. ncbi request reprint The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides
    M H Fittkau
    Cardiovascular Research Unit, Christian Barnard Department of Cardiothoracic Surgery, Cape Heart Centre, University of Cape Town, Anzio Road, 7925 Observatory, Cape Town, South Africa
    Biomaterials 26:167-74. 2005
  5. ncbi request reprint MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing
    D Seliktar
    Institute for Biomedical Engineering, Swiss Federal Institute of Technology and University of Zurich, Moussonstrasse 18, CH 8044 Zurich, Switzerland
    J Biomed Mater Res A 68:704-16. 2004
  6. ncbi request reprint Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition
    M P Lutolf
    Department of Materials and Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland
    Biomacromolecules 4:713-22. 2003
  7. pmc Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics
    M P Lutolf
    Department of Materials and Institute for Biomedical Engineering, Swiss Federal Institute of Technology and University of Zurich, CH 8044 Zurich, Switzerland
    Proc Natl Acad Sci U S A 100:5413-8. 2003
  8. ncbi request reprint Poly(ethylene glycol) block copolymers
    N Tirelli
    Institute for Biomedical Engineering and Department of Materials, Swiss Federal Institute of Technology and University of Zurich
    J Biotechnol 90:3-15. 2002
  9. ncbi request reprint Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids
    M P Lutolf
    Department of Materials and Institute for Biomedical Engineering, ETH Zurich and the University of Zurich, Zurich, Switzerland
    Bioconjug Chem 12:1051-6. 2001
  10. ncbi request reprint Protein delivery from materials formed by self-selective conjugate addition reactions
    D L Elbert
    Institute for Biomedical Engineering and Department of Materials, Swiss Federal Institute of Technology and University of Zurich, Moussonstrasse 18, CH-8044, Zurich, Switzerland
    J Control Release 76:11-25. 2001

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
    M P Lutolf
    Integrative Biosciences Institute, Ecole Polytechnique Federale de Lausanne EPFL, Building AA B 039, CH 1015 Lausanne, Switzerland
    Nat Biotechnol 23:47-55. 2005
    ....
  2. ncbi request reprint Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs
    G P Raeber
    Institute of Bioengineering and Institute of Chemical Sciences and Engineering, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
    Acta Biomater 3:615-29. 2007
    ....
  3. pmc Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration
    G P Raeber
    Integrative Biosciences Institute and Institute for Chemical Science and Engineering, Ecole Polytechnique Federale de Lausanne EPFL, Switzerland
    Biophys J 89:1374-88. 2005
    ....
  4. ncbi request reprint The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides
    M H Fittkau
    Cardiovascular Research Unit, Christian Barnard Department of Cardiothoracic Surgery, Cape Heart Centre, University of Cape Town, Anzio Road, 7925 Observatory, Cape Town, South Africa
    Biomaterials 26:167-74. 2005
    ..05). No corresponding effect was observed for HVSMC. This suggests that the desired response of specific cell types to tissue engineering scaffolds could be optimized through a combinatory approach to the use of biomimetic peptides...
  5. ncbi request reprint MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing
    D Seliktar
    Institute for Biomedical Engineering, Swiss Federal Institute of Technology and University of Zurich, Moussonstrasse 18, CH 8044 Zurich, Switzerland
    J Biomed Mater Res A 68:704-16. 2004
    ..Functionalized PEG-peptide hydrogels could help restore the native vessel wall and improve the performance of angioplasty procedures...
  6. ncbi request reprint Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition
    M P Lutolf
    Department of Materials and Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland
    Biomacromolecules 4:713-22. 2003
    ..Hydrogels were also prepared with varying macromer structures, and their properties were shown to respond to both macromer functionality and molecular weight...
  7. pmc Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics
    M P Lutolf
    Department of Materials and Institute for Biomedical Engineering, Swiss Federal Institute of Technology and University of Zurich, CH 8044 Zurich, Switzerland
    Proc Natl Acad Sci U S A 100:5413-8. 2003
    ..These hydrogels may be useful in tissue engineering and cell biology as alternatives for naturally occurring extracellular matrix-derived materials such as fibrin or collagen...
  8. ncbi request reprint Poly(ethylene glycol) block copolymers
    N Tirelli
    Institute for Biomedical Engineering and Department of Materials, Swiss Federal Institute of Technology and University of Zurich
    J Biotechnol 90:3-15. 2002
    ....
  9. ncbi request reprint Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids
    M P Lutolf
    Department of Materials and Institute for Biomedical Engineering, ETH Zurich and the University of Zurich, Zurich, Switzerland
    Bioconjug Chem 12:1051-6. 2001
    ..These results provide a basis for the rational design of peptides, where the kinetics and thus selectivity of protein/peptide conjugation with polymeric structures via Michael-type addition reactions can be controlled...
  10. ncbi request reprint Protein delivery from materials formed by self-selective conjugate addition reactions
    D L Elbert
    Institute for Biomedical Engineering and Department of Materials, Swiss Federal Institute of Technology and University of Zurich, Moussonstrasse 18, CH-8044, Zurich, Switzerland
    J Control Release 76:11-25. 2001
    ..Utilizing the Flory-Rehner and Peppas-Merrill equations, a framework for modeling the protein release from the gels is described...