Genomes and Genes
Affiliation: Stanford University
- Rho family GTP-binding proteins in growth cone signallingL Luo
Howard Hughes Medical Institute, Department of Physiology, University of California at San Francisco, California 94143, USA
Curr Opin Neurobiol 7:81-6. 1997..Recent evidence suggests that they may also be important components of the signalling pathways that link the reception of extracellular cues to the regulation of the cytoskeleton in neuronal growth cones...
- Genghis Khan (Gek) as a putative effector for Drosophila Cdc42 and regulator of actin polymerizationL Luo
Howard Hughes Medical Institute, Department of Physiology, University of California, San Francisco 94143, USA
Proc Natl Acad Sci U S A 94:12963-8. 1997..These phenotypes can be rescued by a wild-type gek transgene. Our results suggest that this multidomain protein kinase is an effector for the regulation of actin polymerization by Cdc42...
- split ends encodes large nuclear proteins that regulate neuronal cell fate and axon extension in the Drosophila embryoB Kuang
Howard Hughes Medical Institute, Department of Cell Biology, Vanderbilt University Medical Center, Nashville TN 37232 0295, USA
Development 127:1517-29. 2000..We propose that Spen proteins regulate the expression of key effectors of signaling pathways required to specify neuronal cell fate and morphology...
- Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusionL Luo
Howard Hughes Medical Institute, Department of Physiology, University of California at San Francisco 94143
Genes Dev 8:1787-802. 1994..Expressions of analogous mutant Dcdc42 proteins cause qualitatively distinct morphological defects, suggesting that similar GTPases in the same subfamily have unique roles in morphogenesis...