DOUGLAS FREDERICK LEVINSON

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Genetics of recurrent early-onset major depression (GenRED): significant linkage on chromosome 15q25-q26 after fine mapping with single nucleotide polymorphism markers
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 701A Welch Rd, Suite 3325, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 164:259-64. 2007
  2. ncbi request reprint Genome-wide association study of multiplex schizophrenia pedigrees
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, Calif, USA
    Am J Psychiatry 169:963-73. 2012
  3. pmc Statistical corrections of linkage data suggest predominantly cis regulations of gene expression
    Jianxin Shi
    Department of Psychiatry and Behavioral Sciences, Stanford University, 701A Welch Road, Suite 3325, Stanford, California 94305, USA
    BMC Proc 1:S145. 2007
  4. doi request reprint Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 168:302-16. 2011
  5. ncbi request reprint Genetics of recurrent early-onset major depression (GenRED): final genome scan report
    Peter Holmans
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 701A Welch Rd, Suite 3325, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 164:248-58. 2007
  6. pmc Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3
    Ranjana Verma
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Biol Psychiatry 63:1185-9. 2008
  7. pmc Genome-wide linkage and follow-up association study of postpartum mood symptoms
    Pamela Belmonte Mahon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
    Am J Psychiatry 166:1229-37. 2009
  8. pmc Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia
    Jubao Duan
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare and Feinberg School of Medicine, Northwestern University, Evanston, IL, USA
    Am J Hum Genet 75:624-38. 2004
  9. pmc QuickSNP: an automated web server for selection of tagSNPs
    Deepak Grover
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Nucleic Acids Res 35:W115-20. 2007
  10. ncbi request reprint Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression
    Ranjana Verma
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Med Genet B Neuropsychiatr Genet 144:1079-82. 2007

Research Grants

  1. Multicenter Genetics Studies of Schizophrenia
    Douglas Levinson; Fiscal Year: 2006
  2. GENETIC LINKAGE OF SCHIZOPHRENIA AND RELATED STUDIES
    Douglas Levinson; Fiscal Year: 2005
  3. Genetics of Early-Onset Depression
    Douglas Levinson; Fiscal Year: 2007
  4. Genome-Wide Association Study of Schizophrenia
    Douglas Levinson; Fiscal Year: 2007
  5. MOLECULAR GENETICS OF SCHIZOPHRENIA
    Douglas Levinson; Fiscal Year: 2007
  6. MOLECULAR GENETICS OF SCHIZOPHRENIA
    Douglas Levinson; Fiscal Year: 2002
  7. MULTICENTER GENETIC STUDIES OF SCHIZOPHRENIA
    Douglas Levinson; Fiscal Year: 2002
  8. GENETICS OF RECURRENT EARLY-ONSET DEPRESSION
    Douglas Levinson; Fiscal Year: 2002

Detail Information

Publications15

  1. ncbi request reprint Genetics of recurrent early-onset major depression (GenRED): significant linkage on chromosome 15q25-q26 after fine mapping with single nucleotide polymorphism markers
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 701A Welch Rd, Suite 3325, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 164:259-64. 2007
    ....
  2. ncbi request reprint Genome-wide association study of multiplex schizophrenia pedigrees
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, Calif, USA
    Am J Psychiatry 169:963-73. 2012
    ..The authors used a genome-wide association study (GWAS) of multiply affected families to investigate the association of schizophrenia to common single-nucleotide polymorphisms (SNPs) and rare copy number variants (CNVs)...
  3. pmc Statistical corrections of linkage data suggest predominantly cis regulations of gene expression
    Jianxin Shi
    Department of Psychiatry and Behavioral Sciences, Stanford University, 701A Welch Road, Suite 3325, Stanford, California 94305, USA
    BMC Proc 1:S145. 2007
    ..4, LOD = 8.9), we detected linkage for the expression levels of 22 genes, 19 of which are cis. Limiting the analysis to cis regions, linkage was detected to the expression levels of 46 genes with 4.6 expected false positives (FDR = 10%)...
  4. doi request reprint Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications
    Douglas F Levinson
    Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 168:302-16. 2011
    ....
  5. ncbi request reprint Genetics of recurrent early-onset major depression (GenRED): final genome scan report
    Peter Holmans
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 701A Welch Rd, Suite 3325, Palo Alto, CA 94304 5797, USA
    Am J Psychiatry 164:248-58. 2007
    ....
  6. pmc Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3
    Ranjana Verma
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Biol Psychiatry 63:1185-9. 2008
    ..Here we present initial linkage-disequilibrium (LD) fine mapping of this signal and sequence analysis of NTRK3 (neurotrophic receptor kinase-3), a biologically plausible candidate gene...
  7. pmc Genome-wide linkage and follow-up association study of postpartum mood symptoms
    Pamela Belmonte Mahon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
    Am J Psychiatry 166:1229-37. 2009
    ..The authors then fine-mapped their best linkage regions, assessing single nucleotide polymorphisms (SNPs) for genetic association with postpartum symptoms...
  8. pmc Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia
    Jubao Duan
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, Evanston Northwestern Healthcare and Feinberg School of Medicine, Northwestern University, Evanston, IL, USA
    Am J Hum Genet 75:624-38. 2004
    ..These data provide strong preliminary evidence that TRAR4 is a candidate gene for schizophrenia; replication is currently being attempted in additional clinical samples...
  9. pmc QuickSNP: an automated web server for selection of tagSNPs
    Deepak Grover
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Nucleic Acids Res 35:W115-20. 2007
    ..The server is freely available and can be accessed at the URL http://bioinformoodics.jhmi.edu/quickSNP.pl...
  10. ncbi request reprint Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression
    Ranjana Verma
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Med Genet B Neuropsychiatr Genet 144:1079-82. 2007
    ..2%, P = 0.15). None of the tag SNPs showed any evidence of association. Our results do not support a major role for either common or rare p11 SNPs with MDD. Several limitations of the study are discussed...
  11. pmc A comparison of the familiality of chronic depression in recurrent early-onset depression pedigrees using different definitions of chronicity
    Francis M Mondimore
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    J Affect Disord 100:171-7. 2007
    ..Because familial clustering is one component of diagnostic validity we compared family clustering of chronicity as defined in the DSM-IV to that of chronicity determined by an assessment of lifetime course of depressive illness...
  12. pmc Common variants on chromosome 6p22.1 are associated with schizophrenia
    Jianxin Shi
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California 94304, USA
    Nature 460:753-7. 2009
    ..These results demonstrate that common schizophrenia susceptibility alleles can be detected. The characterization of these signals will suggest important directions for research on susceptibility mechanisms...
  13. pmc Narcolepsy is strongly associated with the T-cell receptor alpha locus
    Joachim Hallmayer
    Center for Sleep Sciences, Stanford University School of Medicine, Palo Alto, California, USA
    Nat Genet 41:708-11. 2009
    ....
  14. doi request reprint The Internet-based MGS2 control sample: self report of mental illness
    Alan R Sanders
    Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, NorthShore University Healthsystem, Evanston, Ill 60201 3137, USA
    Am J Psychiatry 167:854-65. 2010
    ..The Molecular Genetics of Schizophrenia (MGS2) project recruited an adult control sample of non-Hispanic European-ancestry (N=3,364) and African American (N=1,301) subjects...
  15. doi request reprint Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees
    Jennifer L Payne
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, 550 N Broadway, Baltimore, MD 21205, USA
    Arch Womens Ment Health 12:27-34. 2009
    ..Limitations include the retrospective interview, the lack of data on premenstrual dysphoric disorder, and the inability to control for factors such as medication use...

Research Grants29

  1. Multicenter Genetics Studies of Schizophrenia
    Douglas Levinson; Fiscal Year: 2006
    ....
  2. GENETIC LINKAGE OF SCHIZOPHRENIA AND RELATED STUDIES
    Douglas Levinson; Fiscal Year: 2005
    ..abstract_text> ..
  3. Genetics of Early-Onset Depression
    Douglas Levinson; Fiscal Year: 2007
    ..abstract_text> ..
  4. Genome-Wide Association Study of Schizophrenia
    Douglas Levinson; Fiscal Year: 2007
    ....
  5. MOLECULAR GENETICS OF SCHIZOPHRENIA
    Douglas Levinson; Fiscal Year: 2007
    ..The goal of the study is to identify one or more SZ susceptibility genes whose subsequent characterization inmolecular and functional studies will elucidate the pathophysiology and treatment of SZ. ..
  6. MOLECULAR GENETICS OF SCHIZOPHRENIA
    Douglas Levinson; Fiscal Year: 2002
    ..Power analyses suggest that this study would have excellent power to detect loci associated with lambda sibs of 1.4, and moderate power for a value of 1.3, i.e., loci with relatively small etiologic effects. ..
  7. MULTICENTER GENETIC STUDIES OF SCHIZOPHRENIA
    Douglas Levinson; Fiscal Year: 2002
    ..These studies may assist investigators in determining which candidate regions are most deserving of intensive efforts to find disease-related genes, and the most likely locations of these genes within the regions. ..
  8. GENETICS OF RECURRENT EARLY-ONSET DEPRESSION
    Douglas Levinson; Fiscal Year: 2002
    ..A timetable is proposed for rapid sharing of all biological materials, blinded clinical data, genotypes and linkage analyses with the scientific community through the NIMH-sponsored Center for Genetic Studies. ..