Kevin V Lemley

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi Podocytopenia and disease severity in IgA nephropathy
    Kevin V Lemley
    Division of Pediatric Nephrology, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Kidney Int 61:1475-85. 2002
  2. ncbi Neonatal nephrotic presentation of a child with heterozygous NPHS1 mutation
    Kevin V Lemley
    Division of Nephrology, S161, Stanford University Medical Center, Stanford, CA 94305 5114, USA
    Pediatr Nephrol 21:864-6. 2006
  3. ncbi Modeling GFR trajectories in diabetic nephropathy
    Kevin V Lemley
    Division of Pediatric Nephrology, Stanford Univ School of Medicine, Stanford, CA 94305 5208, USA
    Am J Physiol Renal Physiol 289:F863-70. 2005
  4. ncbi Prediction of early progression in recently diagnosed IgA nephropathy
    Kevin V Lemley
    Division of Nephrology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Nephrol Dial Transplant 23:213-22. 2008
  5. ncbi Determinants of glomerular hypofiltration in aging humans
    Khoi Hoang
    Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Kidney Int 64:1417-24. 2003
  6. pmc Estimation of glomerular podocyte number: a selection of valid methods
    Kevin V Lemley
    Division of Nephrology, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
    J Am Soc Nephrol 24:1193-202. 2013
  7. pmc Gene expression in the normal adult human kidney assessed by complementary DNA microarray
    John P T Higgins
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Mol Biol Cell 15:649-56. 2004
  8. doi Diabetes and chronic kidney disease: lessons from the Pima Indians
    Kevin V Lemley
    Division of Nephrology, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA
    Pediatr Nephrol 23:1933-40. 2008
  9. doi When to initiate ACEI/ARB therapy in patients with type 1 and 2 diabetes
    Kevin V Lemley
    Division of Nephrology, MS 40, Childrens Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
    Pediatr Nephrol 25:2021-34. 2010
  10. pmc Kidney disease in nail-patella syndrome
    Kevin V Lemley
    Division of Nephrology, MS 40, Childrens Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
    Pediatr Nephrol 24:2345-54. 2009

Collaborators

Detail Information

Publications16

  1. ncbi Podocytopenia and disease severity in IgA nephropathy
    Kevin V Lemley
    Division of Pediatric Nephrology, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Kidney Int 61:1475-85. 2002
    ..The present study was designed to investigate functional and morphological covariates of disease severity in patients with IgA nephropathy...
  2. ncbi Neonatal nephrotic presentation of a child with heterozygous NPHS1 mutation
    Kevin V Lemley
    Division of Nephrology, S161, Stanford University Medical Center, Stanford, CA 94305 5114, USA
    Pediatr Nephrol 21:864-6. 2006
    ....
  3. ncbi Modeling GFR trajectories in diabetic nephropathy
    Kevin V Lemley
    Division of Pediatric Nephrology, Stanford Univ School of Medicine, Stanford, CA 94305 5208, USA
    Am J Physiol Renal Physiol 289:F863-70. 2005
    ....
  4. ncbi Prediction of early progression in recently diagnosed IgA nephropathy
    Kevin V Lemley
    Division of Nephrology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Nephrol Dial Transplant 23:213-22. 2008
    ..Most studies of prognosis in IgA nephropathy (IgAN) have tried to predict dichotomous outcomes based on a small number of clinical or semi-quantitative histological variables in large numbers of patients...
  5. ncbi Determinants of glomerular hypofiltration in aging humans
    Khoi Hoang
    Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Kidney Int 64:1417-24. 2003
    ..The purpose of the present study was to confirm the extent to which glomerular filtration rate (GFR) is depressed in healthy, aging subjects and to elucidate the mechanism of such hypofiltration...
  6. pmc Estimation of glomerular podocyte number: a selection of valid methods
    Kevin V Lemley
    Division of Nephrology, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
    J Am Soc Nephrol 24:1193-202. 2013
    ..We propose the use of the disector/fractionator method for studies in which controlled sectioning of tissue is feasible, reserving the Weibel and Gomez method for studies based on archival or routine pathology material. ..
  7. pmc Gene expression in the normal adult human kidney assessed by complementary DNA microarray
    John P T Higgins
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Mol Biol Cell 15:649-56. 2004
    ..The distinctive patterns of gene expression in discrete portions of the kidney may serve as a resource for further understanding of renal physiology and the molecular and cellular organization of the nephron...
  8. doi Diabetes and chronic kidney disease: lessons from the Pima Indians
    Kevin V Lemley
    Division of Nephrology, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA
    Pediatr Nephrol 23:1933-40. 2008
    ..At this point, most evidence in humans suggests detachment of intact podocytes from the glomerular basement membrane, rather than apoptosis, as the predominant mechanism of podocyte loss...
  9. doi When to initiate ACEI/ARB therapy in patients with type 1 and 2 diabetes
    Kevin V Lemley
    Division of Nephrology, MS 40, Childrens Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
    Pediatr Nephrol 25:2021-34. 2010
    ..Recent studies suggest that very early initiation of ACEI/ARB therapy may not have demonstrable beneficial effects even over a period of years...
  10. pmc Kidney disease in nail-patella syndrome
    Kevin V Lemley
    Division of Nephrology, MS 40, Childrens Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
    Pediatr Nephrol 24:2345-54. 2009
    ..g. NPHS2, CD2AP), the transription of which is regulated by LMX1B...
  11. doi Protecting podocytes: how good do we need to be?
    Kevin V Lemley
    Division of Nephrology, Children s Hospital Los Angeles, Los Angeles, California 90027, USA
    Kidney Int 81:9-11. 2012
    ..Quantitative monitoring of podocyte loss (e.g., to assess therapy) remains a challenge...
  12. pmc Urinary excretion of viable podocytes in health and renal disease
    Stefanie U Vogelmann
    Division of Nephrology, Department of Medicine, Stanford University School of Medicine, CA 94305, USA
    Am J Physiol Renal Physiol 285:F40-8. 2003
    ....
  13. ncbi National Kidney Foundation's Kidney Disease Outcomes Quality Initiative clinical practice guidelines for chronic kidney disease in children and adolescents: evaluation, classification, and stratification
    Ronald J Hogg
    North Texas Hospital for Children and the Department of Clinical Research at Medical City Dallas Hospital, Dallas, Texas 75230, USA
    Pediatrics 111:1416-21. 2003
    ....
  14. ncbi Podocytes, parietal cells, and glomerular pathology: the role of cell cycle proteins
    Michio Nagata
    Department of Pathology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, 305 8575, Tsukuba, Japan
    Pediatr Nephrol 18:3-8. 2003
    ..This review discusses the role of cell cycle molecules in the differentiation, function, and pathology of podocytes...
  15. doi Yet more ways to skin a cat: nephrin mutations outside the neonatal period
    Kevin V Lemley
    J Am Soc Nephrol 19:1837-8. 2008
  16. ncbi The effect of dopamine on glomerular filtration rate in normotensive, oliguric premature neonates
    Susan K Lynch
    Department of Pediatrics, West Virginia University School of Medicine, West Virginia, USA
    Pediatr Nephrol 18:649-52. 2003
    ..5 micro g/kg per min of dopamine. This probably reflects the effects of afferent vasodilatation and may be important clinically when enhancement of GFR is the major treatment objective...