QUYNH THU XUAN LE

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Long-term outcomes after external beam irradiation and brachytherapy boost for base-of-tongue cancers
    Iris C Gibbs
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5302, USA
    Int J Radiat Oncol Biol Phys 57:489-94. 2003
  2. ncbi request reprint Extranodal nonorbital indolent lymphomas of the head and neck: relationship between tumor control and radiotherapy
    Dhara MacDermed
    Department of Radiation Oncology, Stanford University Medical Center, CA 94305, USA
    Int J Radiat Oncol Biol Phys 59:788-95. 2004
  3. pmc Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis
    Stephanie T Chang
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA
    J Transl Med 7:105. 2009
  4. pmc The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways
    Donald Courter
    Department of Radiation Oncology, Stanford University, Stanford, California, United States of America
    PLoS ONE 5:e9633. 2010
  5. pmc An international collaboration to harmonize the quantitative plasma Epstein-Barr virus DNA assay for future biomarker-guided trials in nasopharyngeal carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, 875 Blake Wilbur Dr, MC 5847, Stanford, CA 94305, USA
    Clin Cancer Res 19:2208-15. 2013
  6. ncbi request reprint Volumetric-modulated arc radiotherapy for skull-base and non-skull-base head and neck cancer: a treatment planning comparison with fixed Beam IMRT
    J Chen
    Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China
    Technol Cancer Res Treat 12:11-8. 2013
  7. pmc Prognostic and predictive significance of plasma HGF and IL-8 in a phase III trial of chemoradiation with or without tirapazamine in locoregionally advanced head and neck cancer
    Quynh Thu Le
    Radiation Oncology and Pathology, Stanford University, Stanford, CA, USA
    Clin Cancer Res 18:1798-807. 2012
  8. pmc In vivo 1H magnetic resonance spectroscopy of lactate in patients with stage IV head and neck squamous cell carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 71:1151-7. 2008
  9. ncbi request reprint Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 69:167-75. 2007
  10. ncbi request reprint Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, California, USA
    J Thorac Oncol 1:802-9. 2006

Research Grants

  1. Defining Molecular Markers for Tumor Hypoxia
    Quynh Thu Le; Fiscal Year: 2007
  2. Defining Molecular Markers for Tumor Hypoxia
    QUYNH THU XUAN LE; Fiscal Year: 2010
  3. Defining Molecular Markers for Tumor Hypoxia
    Quynh Thu Le; Fiscal Year: 2006
  4. Defining Molecular Markers for Tumor Hypoxia
    Quynh Thu Le; Fiscal Year: 2009
  5. Defining Molecular Markers for Tumor Hypoxia
    Quynh Thu Le; Fiscal Year: 2009

Detail Information

Publications55

  1. ncbi request reprint Long-term outcomes after external beam irradiation and brachytherapy boost for base-of-tongue cancers
    Iris C Gibbs
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5302, USA
    Int J Radiat Oncol Biol Phys 57:489-94. 2003
    ..To assess long-term efficacy and toxicity associated with external beam irradiation (EBRT) and interstitial (192)Ir implantation for the treatment of squamous carcinoma of the base of tongue...
  2. ncbi request reprint Extranodal nonorbital indolent lymphomas of the head and neck: relationship between tumor control and radiotherapy
    Dhara MacDermed
    Department of Radiation Oncology, Stanford University Medical Center, CA 94305, USA
    Int J Radiat Oncol Biol Phys 59:788-95. 2004
    ..To review our experience managing extranodal nonorbital indolent lymphomas of the head and neck...
  3. pmc Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis
    Stephanie T Chang
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA
    J Transl Med 7:105. 2009
    ..Proximity ligation assay (PLA) is a highly sensitive technique for multiplex detection of biomarkers in plasma with little or no interfering background signal...
  4. pmc The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways
    Donald Courter
    Department of Radiation Oncology, Stanford University, Stanford, California, United States of America
    PLoS ONE 5:e9633. 2010
    ..Here, we use genetic approaches to systematically investigate the function of the RGD domain in different OPN isoforms on tumor progression and metastasis for 2 different solid tumor models...
  5. pmc An international collaboration to harmonize the quantitative plasma Epstein-Barr virus DNA assay for future biomarker-guided trials in nasopharyngeal carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, 875 Blake Wilbur Dr, MC 5847, Stanford, CA 94305, USA
    Clin Cancer Res 19:2208-15. 2013
    ..However, assay standardization is necessary for use in biomarker-driven trials. We conducted a study to harmonize the method between four centers with expertise in EBV DNA quantitation...
  6. ncbi request reprint Volumetric-modulated arc radiotherapy for skull-base and non-skull-base head and neck cancer: a treatment planning comparison with fixed Beam IMRT
    J Chen
    Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China
    Technol Cancer Res Treat 12:11-8. 2013
    ..Dosimetrically, both approaches were equivalent for non-skull-base tumor with VMAT using fewer MUs and shorter delivery time...
  7. pmc Prognostic and predictive significance of plasma HGF and IL-8 in a phase III trial of chemoradiation with or without tirapazamine in locoregionally advanced head and neck cancer
    Quynh Thu Le
    Radiation Oncology and Pathology, Stanford University, Stanford, CA, USA
    Clin Cancer Res 18:1798-807. 2012
    ..We evaluated the role of circulating HGF and IL-8 as prognostic and predictive factors for efficacy of tirapazamine (TPZ), a hypoxic cell cytotoxin...
  8. pmc In vivo 1H magnetic resonance spectroscopy of lactate in patients with stage IV head and neck squamous cell carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 71:1151-7. 2008
    ..To investigate in vivo(1)H magnetic resonance spectroscopy imaging of lactate for assessing tumor hypoxia in head and neck cancers and to determine its utility in predicting the response and outcomes...
  9. ncbi request reprint Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 69:167-75. 2007
    ..To investigate the expression pattern of hypoxia-induced proteins identified as being involved in malignant progression of head-and-neck squamous cell carcinoma (HNSCC) and to determine their relationship to tumor pO(2) and prognosis...
  10. ncbi request reprint Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, California, USA
    J Thorac Oncol 1:802-9. 2006
    ..The purpose of this study was to report initial results of a phase I study using single-fraction stereotactic radiotherapy (RT) in patients with inoperable lung tumors...
  11. ncbi request reprint Nonsurgical therapy for stages I and II non-small cell lung cancer
    Quynh Thu Le
    Department of Radiation Oncology, Stanford Cancer Center, 875 Blake Wilbur Drive, MC 5847, Stanford University, Stanford, CA 94305 5847, USA
    Hematol Oncol Clin North Am 19:237-61, v-vi. 2005
    ....
  12. ncbi request reprint Mature results from a randomized Phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Cancer 106:1940-9. 2006
    ....
  13. ncbi request reprint Galectin-1: a link between tumor hypoxia and tumor immune privilege
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, 875 Blake Wilbur Drive, Stanford, CA 94305 5847, USA
    J Clin Oncol 23:8932-41. 2005
    ..To identify a 15-KDa novel hypoxia-induced secreted protein in head and neck squamous cell carcinomas (HNSCC) and to determine its role in malignant progression...
  14. pmc Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 69:S56-8. 2007
  15. ncbi request reprint A comparison study of different PCR assays in measuring circulating plasma epstein-barr virus DNA levels in patients with nasopharyngeal carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5407, USA
    Clin Cancer Res 11:5700-7. 2005
    ..To compare the performance of three PCR assays in measuring circulating Epstein-Barr virus (EBV). DNA levels in nasopharyngeal carcinoma patients and to confirm its prognostic significance...
  16. pmc Clinical biomarkers for hypoxia targeting
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, 875 Blake Wilbur Dr, MC 5847, Stanford, CA 94305 5847, USA
    Cancer Metastasis Rev 27:351-62. 2008
    ..This chapter will focus on the development of clinical biomarkers for hypoxia targeting...
  17. pmc Integrating biologically targeted therapy in head and neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
    Semin Radiat Oncol 19:53-62. 2009
    ....
  18. doi request reprint Palifermin reduces severe mucositis in definitive chemoradiotherapy of locally advanced head and neck cancer: a randomized, placebo-controlled study
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA
    J Clin Oncol 29:2808-14. 2011
    ..This randomized, placebo-controlled, double-blind study evaluated the efficacy and safety of palifermin to reduce OM associated with definitive chemoradiotherapy for locally advanced HNC...
  19. pmc Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
    J Clin Oncol 27:4281-6. 2009
    ..To validate lysyl oxidase (LOX), a hypoxia-related protein, as a marker for metastasis in an independent head and neck cancer (HNC) patient group enrolled onto a prospective trial...
  20. pmc Phase II study of tirapazamine, cisplatin, and etoposide and concurrent thoracic radiotherapy for limited-stage small-cell lung cancer: SWOG 0222
    Quynh Thu X Le
    Stanford University, Stanford, CA, USA
    J Clin Oncol 27:3014-9. 2009
    ..We report results of the phase II study designed to confirm this result...
  21. ncbi request reprint An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, California 94305 5847, USA
    Clin Cancer Res 12:1507-14. 2006
    ..To directly assess tumor oxygenation in resectable non-small cell lung cancers (NSCLC) and to correlate tumor pO2 and the selected gene and protein expression to treatment outcomes...
  22. ncbi request reprint Metabolic tumor burden predicts for disease progression and death in lung cancer
    Percy Lee
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 69:328-33. 2007
    ..However, stage may be simply a surrogate for underlying tumor burden. Our purpose was to assess the prognostic value of tumor burden measured by 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging...
  23. ncbi request reprint Lysyl oxidase is essential for hypoxia-induced metastasis
    Janine T Erler
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 440:1222-6. 2006
    ..Furthermore, LOX may be required to create a niche permissive for metastatic growth. Our findings indicate that LOX is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases...
  24. ncbi request reprint Plasma osteopontin is an independent prognostic marker for head and neck cancers
    David Petrik
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    J Clin Oncol 24:5291-7. 2006
    ..To confirm the relationship between plasma osteopontin (OPN) levels and treatment outcomes in head and neck squamous cell carcinoma (HNSCC) patients in an expanded study...
  25. ncbi request reprint Quantification of motion of different thoracic locations using four-dimensional computed tomography: implications for radiotherapy planning
    Peter G Maxim
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 69:1395-401. 2007
    ....
  26. doi request reprint Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file
    Louis Lee
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 70:634-44. 2008
    ..The aim of this work is to reconstruct the intensity-modulated radiation therapy dose delivered to an HN patient using the CBCT and multileaf collimator (MLC) log-files...
  27. doi request reprint Linac-based on-board imaging feasibility and the dosimetric consequences of head roll in head-and-neck IMRT plans
    Gwe Ya Kim
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    Med Dosim 33:93-9. 2008
    ....
  28. ncbi request reprint Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling
    Yijun Chen
    Department of Radiation Oncology, Center for Clinical Sciences Research, Department of Surgery, Palo Alto VA Health Care System, Palo Alto, CA, USA
    Cancer Res 64:7302-10. 2004
    ..These data suggest that IKKbeta is a novel endogenous marker of tumor hypoxia and may represent a new target for anticancer therapy...
  29. ncbi request reprint Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5302, USA
    Int J Radiat Oncol Biol Phys 56:1046-54. 2003
    ..Stereotactic radiosurgery (STR) was used to boost the tumor site after EBRT to improve local control...
  30. ncbi request reprint Sample classification from protein mass spectrometry, by 'peak probability contrasts'
    Robert Tibshirani
    Department of Health, Research and Policy, Stanford University, CA 94305, USA
    Bioinformatics 20:3034-44. 2004
    ..We illustrate the method on matrix-assisted laser desorption and ionization mass spectrometry data from a study of ovarian cancers...
  31. ncbi request reprint Lens dose in MLC-based IMRT treatments of the head and neck
    Todd Pawlicki
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5487, USA
    Int J Radiat Oncol Biol Phys 59:293-9. 2004
    ....
  32. ncbi request reprint Therapeutic exploitation of the physiological and molecular genetic alterations in head and neck cancer
    Quynh Thu Le
    Stanford University School of Medicine, Department of Radiation Oncology, Stanford, California 94305 5032, USA
    Clin Cancer Res 9:4287-95. 2003
    ..This review will summarize these new molecular and physiological based strategies that can be used for both treatment and chemoprevention of head and neck squamous cell carcinoma...
  33. ncbi request reprint Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 56:375-83. 2003
    ..To compare the Eppendorf PO2 histograph and the alkaline comet assay as methods of measuring tumor hypoxia in patients with head-and-neck squamous cell carcinomas...
  34. ncbi request reprint Stereotactic radiosurgery for lung tumors: preliminary report of a phase I trial
    Richard I Whyte
    Department of Cardiothoracic Surgery, Stanford University, Stanford, California 94305 5407, USA
    Ann Thorac Surg 75:1097-101. 2003
    ..Stereotactic radiosurgery is well established for the treatment of intracranial neoplasms but its use for lung tumors is novel...
  35. ncbi request reprint Patterns of patient movement during frameless image-guided radiosurgery
    Martin J Murphy
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 55:1400-8. 2003
    ..We have analyzed the target position records for all of these cases to assess the frequency, magnitude, and case-by-case patterns of patient movement...
  36. ncbi request reprint Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Center for Clinical Science Research South, Stanford, California 94305 5152, USA
    Clin Cancer Res 9:59-67. 2003
    ..Tumor hypoxia modifies treatment efficacy and promotes tumor progression. Here, we investigated the relationship between osteopontin (OPN), tumor pO(2), and prognosis in patients with head and neck squamous cell carcinomas (HNSCC)...
  37. ncbi request reprint Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer
    Albert C Koong
    Department of Radiation Oncology, Stanford University School of Medicine, 269 Campus Drive West, Stanford, CA 94305
    Int J Radiat Oncol Biol Phys 63:320-3. 2005
    ..To determine the efficacy of concurrent 5-fluorouracil (5-FU) and intensity-modulated radiotherapy (IMRT) followed by body stereotactic radiosurgery (SRS) in patients with locally advanced pancreatic cancer...
  38. ncbi request reprint The effectiveness of breath-holding to stabilize lung and pancreas tumors during radiosurgery
    Martin J Murphy
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 53:475-82. 2002
    ..To evaluate the effect of breath-holding on the short-term reproducibility and long-term variability of tumor position during image-guided radiosurgery...
  39. ncbi request reprint Lung cancer in women: exploring sex differences in susceptibility, biology, and therapeutic response
    Jessica S Donington
    Department of Cardiothoracic Surgery, Stanford University School of Medicine, CA 94303, USA
    Clin Lung Cancer 8:22-9. 2006
    ..Several phase II trials with small-molecule inhibitors of Src are under way or have been initiated in lung cancer and in other malignancies, as discussed herein...
  40. ncbi request reprint Positron-emission tomography for surveillance of head and neck cancer
    William R Ryan
    Department of Otolaryngology Head and Neck Surgery, Stanford University School of Medicine, Stanford, California 94305, USA
    Laryngoscope 115:645-50. 2005
    ..To determine the diagnostic accuracy and the ideal timing of fluoro-fluorodeoxyglucose positron-emission tomography (PET) in the posttreatment surveillance of head and neck mucosal squamous cell carcinoma (HNSCC)...
  41. ncbi request reprint Clinical role of 18F-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma
    Andrew Quon
    Division of Nuclear Medicine, Department of Radiology, Stanford University Medical Center, Stanford, California 94305, USA
    J Nucl Med 48:58S-67S. 2007
    ....
  42. ncbi request reprint Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer
    Yonghua Zhu
    Department of Radiation Oncology, 875 Blake Wilbur Dr, R CC G228, Stanford University, Stanford, CA 94305, USA
    Oncogene 24:6555-63. 2005
    ..Taken together, these results have identified a new hypoxia responsive transcriptional enhancer that is regulated by Akt signaling...
  43. ncbi request reprint Nasopharyngeal and oropharyngeal carcinomas: target delineation, therapy delivery and stereotactic boost procedures with intensity-modulated/ image-guided radiation therapy
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5302, USA
    Front Radiat Ther Oncol 40:208-31. 2007
    ..In addition, we also present data on the use of stereotactic radiotherapy as a boost to improve local control of nasopharyngeal carcinomas...
  44. ncbi request reprint Phase I study of tirapazamine plus cisplatin/etoposide and concurrent thoracic radiotherapy in limited-stage small cell lung cancer (S0004): a Southwest Oncology Group study
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5847, USA
    Clin Cancer Res 10:5418-24. 2004
    ..To determine the feasibility and a recommended phase II dose of tirapazamine when combined with chemoradiotherapy in limited-stage small cell lung cancer (LSCLC)...
  45. ncbi request reprint Indirect MR lymphangiography of the head and neck using conventional gadolinium contrast: a pilot study in humans
    Billy W Loo
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA, and Department of General Surgery, Singapore General Hospital, Singapore
    Int J Radiat Oncol Biol Phys 66:462-8. 2006
    ....
  46. ncbi request reprint Advanced-staged tonsillar squamous carcinoma: organ preservation versus surgical management of the primary site
    Haider Ali Shirazi
    Department of Radiation Oncology, 875 Blake Wilbur Dr, R CC G228, Stanford University, Stanford, CA 94305, USA
    Head Neck 28:587-94. 2006
    ..Our aim was to review our experience in the management of advanced tonsillar squamous cell carcinoma (SCC) and to compare treatment outcomes between patients treated with and without surgery to the primary site...
  47. ncbi request reprint A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia
    Daniel W Nelson
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5847, USA
    Cancer Res 65:6151-8. 2005
    ..The 5HRE beta-hCG reporter system described here enables serial, noninvasive monitoring of tumor hypoxia in a mouse model by measuring a urinary reporter protein...
  48. ncbi request reprint Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma
    Megan E Daly
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, California 94305, USA
    Head Neck 29:211-20. 2007
    ....
  49. pmc New developments in radiation therapy for head and neck cancer: intensity-modulated radiation therapy and hypoxia targeting
    Nancy Y Lee
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Semin Oncol 35:236-50. 2008
    ..The second half of the review will focus on approaches for assessing tumor hypoxia and on the strategies for targeting this important microenvironmental factor in HNC...
  50. doi request reprint Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma
    Wendy Hara
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 71:393-400. 2008
    ..To determine long-term outcomes in patients receiving stereotactic radiotherapy (SRT) as a boost after external beam radiotherapy (EBRT) for locally advanced nasopharyngeal carcinoma (NPC)...
  51. ncbi request reprint A multidisciplinary approach to management in a patient with bilateral superior sulcus non-small-cell lung carcinoma
    Millie S Roy
    Department of Medicine, Stanford University School of Medicine, CA, USA
    Clin Lung Cancer 8:146-8. 2006
    ....
  52. ncbi request reprint XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
    Lorenzo Romero-Ramirez
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5152, USA
    Cancer Res 64:5943-7. 2004
    ..Taken together, these studies directly implicate XBP1 as an essential survival factor for hypoxic stress and tumor growth...
  53. ncbi request reprint Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms
    Catherine K Su
    Department of Radiation Oncology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5302, USA
    Int J Radiat Oncol Biol Phys 60:171-7. 2004
    ..In a single-institution, double-blind, prospective, randomized trial, we determined whether oral aloe vera gel can reduce radiation-induced mucositis in head-and-neck cancer patients...
  54. ncbi request reprint The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers
    Scott G Soltys
    Department of Radiation Oncology, and Health Policy and Research, Stanford University, Stanford, California 94305 5847, USA
    Clin Cancer Res 10:4806-12. 2004
    ....
  55. ncbi request reprint Hypoxic gene expression and metastasis
    Quynh Thu Le
    Division of Cancer and Radiation Biology, Stanford University School of Medicine, Department of Radiation Oncology, CCSR South, Room 1255, 269 Campus Drive, Stanford, CA 94305 5152
    Cancer Metastasis Rev 23:293-310. 2004
    ..Particular emphasis is given to recent findings that provide insight to the role of hypoxia in the metastatic process...

Research Grants6

  1. Defining Molecular Markers for Tumor Hypoxia
    Quynh Thu Le; Fiscal Year: 2007
    ..We will also conduct proteomic analysis of serial plasma samples obtained from the same patients before and after TPZ to identify novel hypoxia-related secreted proteins that can serve as future biomarkers and targets for new therapy. ..
  2. Defining Molecular Markers for Tumor Hypoxia
    QUYNH THU XUAN LE; Fiscal Year: 2010
    ..abstract_text> ..
  3. Defining Molecular Markers for Tumor Hypoxia
    Quynh Thu Le; Fiscal Year: 2006
    ..We will also conduct proteomic analysis of serial plasma samples obtained from the same patients before and after TPZ to identify novel hypoxia-related secreted proteins that can serve as future biomarkers and targets for new therapy. ..
  4. Defining Molecular Markers for Tumor Hypoxia
    Quynh Thu Le; Fiscal Year: 2009
    ..abstract_text> ..
  5. Defining Molecular Markers for Tumor Hypoxia
    Quynh Thu Le; Fiscal Year: 2009
    ..abstract_text> ..