Maarten G Lansberg

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Concurrent presentation of perimesencephalic subarachnoid hemorrhage and ischemic stroke
    Maarten G Lansberg
    Neurology and Neurological Sciences, Stanford University, Palo Alto, California 94304, USA
    J Stroke Cerebrovasc Dis 17:248-50. 2008
  2. pmc RAPID automated patient selection for reperfusion therapy: a pooled analysis of the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) and the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) Study
    Maarten G Lansberg
    Stanford University, Stanford Stroke Center, 780 Welch Road, Suite 205, Palo Alto, CA 94304, USA
    Stroke 42:1608-14. 2011
  3. pmc Treatment time-specific number needed to treat estimates for tissue plasminogen activator therapy in acute stroke based on shifts over the entire range of the modified Rankin Scale
    Maarten G Lansberg
    Stanford Stroke Center, Stanford University Medical Center, 701 Welch Road, Suite B325, Palo Alto, CA 94304 9705, USA
    Stroke 40:2079-84. 2009
  4. ncbi request reprint Risk factors of symptomatic intracerebral hemorrhage after tPA therapy for acute stroke
    Maarten G Lansberg
    Stanford University, Stanford Stroke Center, Palo Alto, California 94304, USA
    Stroke 38:2275-8. 2007
  5. ncbi request reprint Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors
    Maarten G Lansberg
    Stanford University, Stanford Stroke Center, Palo Alto, CA 94304, USA
    Cerebrovasc Dis 24:1-10. 2007
  6. ncbi request reprint Evaluation of the clinical-diffusion and perfusion-diffusion mismatch models in DEFUSE
    Maarten G Lansberg
    Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304, USA
    Stroke 38:1826-30. 2007
  7. pmc Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis
    Maarten G Lansberg
    Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304 9705, USA
    Stroke 40:2438-41. 2009
  8. doi request reprint The MRA-DWI mismatch identifies patients with stroke who are likely to benefit from reperfusion
    Maarten G Lansberg
    Stanford Stroke Center, 701 Welch Road, Suite B325, Palo Alto, CA 94304 9705, USA
    Stroke 39:2491-6. 2008
  9. pmc Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE)
    Jean Marc Olivot
    Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, 701 Welch Road, Suite 325, Palo Alto, CA 94304, USA
    Stroke 39:2257-63. 2008
  10. pmc Relationships between cerebral perfusion and reversibility of acute diffusion lesions in DEFUSE: insights from RADAR
    Jean Marc Olivot
    Department of Neurology, Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304, USA
    Stroke 40:1692-7. 2009

Research Grants

  1. Who Benefits from tPA 3-6 hours after Stroke
    Maarten Lansberg; Fiscal Year: 2007

Detail Information

Publications37

  1. pmc Concurrent presentation of perimesencephalic subarachnoid hemorrhage and ischemic stroke
    Maarten G Lansberg
    Neurology and Neurological Sciences, Stanford University, Palo Alto, California 94304, USA
    J Stroke Cerebrovasc Dis 17:248-50. 2008
    ..These findings suggest that in some instances perimesencephalic SAH is caused by rupture of a perforating artery...
  2. pmc RAPID automated patient selection for reperfusion therapy: a pooled analysis of the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) and the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) Study
    Maarten G Lansberg
    Stanford University, Stanford Stroke Center, 780 Welch Road, Suite 205, Palo Alto, CA 94304, USA
    Stroke 42:1608-14. 2011
    ..The aim of this study was to determine if automated MRI analysis software (RAPID) can be used to identify patients with stroke in whom reperfusion is associated with an increased chance of good outcome...
  3. pmc Treatment time-specific number needed to treat estimates for tissue plasminogen activator therapy in acute stroke based on shifts over the entire range of the modified Rankin Scale
    Maarten G Lansberg
    Stanford Stroke Center, Stanford University Medical Center, 701 Welch Road, Suite B325, Palo Alto, CA 94304 9705, USA
    Stroke 40:2079-84. 2009
    ..The aim of this study is to calculate treatment time-specific NNT estimates based on shifts over the entire spectrum of clinically relevant functional outcomes...
  4. ncbi request reprint Risk factors of symptomatic intracerebral hemorrhage after tPA therapy for acute stroke
    Maarten G Lansberg
    Stanford University, Stanford Stroke Center, Palo Alto, California 94304, USA
    Stroke 38:2275-8. 2007
    ..MRI-based variables have generally not been included in predictive models, and little is known about the influence of reperfusion on SICH risk...
  5. ncbi request reprint Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors
    Maarten G Lansberg
    Stanford University, Stanford Stroke Center, Palo Alto, CA 94304, USA
    Cerebrovasc Dis 24:1-10. 2007
    ....
  6. ncbi request reprint Evaluation of the clinical-diffusion and perfusion-diffusion mismatch models in DEFUSE
    Maarten G Lansberg
    Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304, USA
    Stroke 38:1826-30. 2007
    ..The clinical-diffusion mismatch (CDM) model is an alternative method that is technically less challenging because it does not require perfusion-weighted imaging. This study is an evaluation of these 2 models in the DEFUSE dataset...
  7. pmc Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis
    Maarten G Lansberg
    Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304 9705, USA
    Stroke 40:2438-41. 2009
    ..The purpose of this study was to produce reliable and precise estimates of the treatment effect of tPA by pooling data from all relevant studies...
  8. doi request reprint The MRA-DWI mismatch identifies patients with stroke who are likely to benefit from reperfusion
    Maarten G Lansberg
    Stanford Stroke Center, 701 Welch Road, Suite B325, Palo Alto, CA 94304 9705, USA
    Stroke 39:2491-6. 2008
    ....
  9. pmc Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE)
    Jean Marc Olivot
    Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, 701 Welch Road, Suite 325, Palo Alto, CA 94304, USA
    Stroke 39:2257-63. 2008
    ..The purpose of this study was to determine the relationships between ischemic lesion growth, recanalization, and clinical response in stroke patients with and without a perfusion/diffusion mismatch...
  10. pmc Relationships between cerebral perfusion and reversibility of acute diffusion lesions in DEFUSE: insights from RADAR
    Jean Marc Olivot
    Department of Neurology, Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304, USA
    Stroke 40:1692-7. 2009
    ..Acute ischemic lesions with restricted diffusion can resolve after early recanalization. The impact of superimposed perfusion abnormalities on the fate of acute diffusion lesions is unclear...
  11. pmc Geography, structure, and evolution of diffusion and perfusion lesions in Diffusion and perfusion imaging Evaluation For Understanding Stroke Evolution (DEFUSE)
    Jean Marc Olivot
    Department of Neurology, Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, Stanford, CA, USA
    Stroke 40:3245-51. 2009
    ..We investigated spatial relationships between final infarcts and early DWI/PWI lesions before and after intravenous thrombolysis in the Diffusion and perfusion imaging Evaluation For Understanding Stroke Evolution (DEFUSE) study...
  12. pmc Refining the definition of the malignant profile: insights from the DEFUSE-EPITHET pooled data set
    Michael Mlynash
    Department of Neurology and Neurological Sciences, Stanford Stroke Center, 780 Welch Road, Suite 205, Stanford, Stanford, CA, USA
    Stroke 42:1270-5. 2011
    ....
  13. pmc Optimal Tmax threshold for predicting penumbral tissue in acute stroke
    Jean Marc Olivot
    Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304, USA
    Stroke 40:469-75. 2009
    ..We sought to assess whether the volume of the ischemic penumbra can be estimated more accurately by altering the threshold selected for defining perfusion-weighting imaging (PWI) lesions...
  14. ncbi request reprint Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study
    Gregory W Albers
    Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, Stanford, CA 94304, USA
    Ann Neurol 60:508-17. 2006
    ..To determine whether prespecified baseline magnetic resonance imaging (MRI) profiles can identify stroke patients who have a robust clinical response after early reperfusion when treated 3 to 6 hours after symptom onset...
  15. pmc Clinical outcomes strongly associated with the degree of reperfusion achieved in target mismatch patients: pooled data from the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution studies
    Manabu Inoue
    Stanford Stroke Center, Stanford University School of Medicine, Stanford, CA 94305, USA
    Stroke 44:1885-90. 2013
    ..We hypothesized that there would be a strong correlation between the degree of reperfusion achieved and clinical outcomes in target mismatch (TMM) patients...
  16. pmc Early diffusion-weighted imaging and perfusion-weighted imaging lesion volumes forecast final infarct size in DEFUSE 2
    Hayley M Wheeler
    Stanford Stroke Center, Stanford University School of Medicine, Stanford, CA 94305, USA
    Stroke 44:681-5. 2013
    ..With incomplete reperfusion, the union of baseline DWI and posttreatment PWI is hypothesized to predict infarct volume...
  17. doi request reprint Automated perfusion imaging for the evaluation of transient ischemic attack
    Jonathan T Kleinman
    Department of Neurology and Neurological Sciences, Stanford Stroke Center, 780 Welch Road, Suite 205, Palo Alto, CA 94304, USA
    Stroke 43:1556-60. 2012
    ....
  18. pmc Comparison of the response to endovascular reperfusion in relation to site of arterial occlusion
    Robin Lemmens
    Stanford Stroke Center, Stanford University of Medicine, Stanford, CA, USA
    Neurology 81:614-8. 2013
    ..We explored the relationship between the site of vascular occlusion and the response to endovascular treatment in patients with acute ischemic stroke and also considered the impact of mismatch profile...
  19. pmc Patients with acute stroke treated with intravenous tPA 3-6 hours after stroke onset: correlations between MR angiography findings and perfusion- and diffusion-weighted imaging in the DEFUSE study
    Michael P Marks
    Department of Radiology, Neurosurgery, Stanford University Medical Center, Stanford, CA 94305 5105, USA
    Radiology 249:614-23. 2008
    ..To study magnetic resonance (MR) angiography findings in patients with acute stroke treated with intravenous tissue plasminogen activator (tPA) in relationship to perfusion- and diffusion-weighted imaging changes and clinical outcome...
  20. doi request reprint Patients with the malignant profile within 3 hours of symptom onset have very poor outcomes after intravenous tissue-type plasminogen activator therapy
    Manabu Inoue
    Stanford Stroke Center, Stanford University Medical Center, Stanford, CA, USA
    Stroke 43:2494-6. 2012
    ....
  21. doi request reprint Patients with single distal MCA perfusion lesions have a high rate of good outcome with or without reperfusion
    Robin Lemmens
    Stanford University, Stanford, CA, USA
    Int J Stroke 9:156-9. 2014
    ..Reperfusion is associated with good functional outcome after stroke. However, minimal data are available regarding the effect of reperfusion on clinical outcome and infarct growth in patients with distal MCA branch occlusions...
  22. doi request reprint MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study
    Maarten G Lansberg
    Stanford Stroke Center, Stanford University School of Medicine, Stanford, CA, USA
    Lancet Neurol 11:860-7. 2012
    ..We aimed to establish whether MRI can be used to identify patients who are most likely to benefit from endovascular reperfusion...
  23. pmc MRI profile of the perihematomal region in acute intracerebral hemorrhage
    Jean Marc Olivot
    Department of Neurology and Neurological Sciences, Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304, USA
    Stroke 41:2681-3. 2010
    ....
  24. pmc Improving dynamic susceptibility contrast MRI measurement of quantitative cerebral blood flow using corrections for partial volume and nonlinear contrast relaxivity: A xenon computed tomographic comparative study
    Greg Zaharchuk
    Department of Radiology, Stanford University, Stanford, California, USA
    J Magn Reson Imaging 30:743-52. 2009
    ....
  25. doi request reprint Two aces: transient ischemic attack work-up as outpatient assessment of clinical evaluation and safety
    Jean Marc Olivot
    Department of Neurology, Stanford Stroke Center, Stanford University Medical Center, 780 Welch Road, Suite 205, Palo Alto, CA 94304, USA
    Stroke 42:1839-43. 2011
    ..To evaluate a novel emergency department-based TIA triage system...
  26. pmc Antithrombotic and thrombolytic therapy for ischemic stroke: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    Maarten G Lansberg
    Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA, USA
    Chest 141:e601S-36S. 2012
    ..This article provides recommendations on the use of antithrombotic therapy in patients with stroke or transient ischemic attack (TIA)...
  27. pmc Favorable outcome from a locked-in state despite extensive pontine infarction by MRI
    Edgar Andres Samaniego
    Stanford Stroke Center, 701 Welch Road, Bldg B, Ste 325, Palo Alto, CA 94304 1702, USA
    Neurocrit Care 11:369-71. 2009
    ..We report on three patients with a locked-in state with unexpected favorable recoveries despite DWI evidence of widespread pontine ischemia...
  28. doi request reprint Stroke Treatment Academic Industry Roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies
    Gregory W Albers
    Stanford Stroke Center, 780 Welch Road, Suite 205, Palo Alto, CA 94304, USA
    Stroke 42:2645-50. 2011
    ....
  29. ncbi request reprint Mechanical thrombectomy following intravenous thrombolysis in the treatment of acute stroke
    Maarten G Lansberg
    Department of Neurology, Stanford University Medical Center, Stanford, Calif 94305, USA
    Arch Neurol 62:1763-5. 2005
    ..Treatment with intravenous thrombolytics followed by mechanical thrombectomy is a novel approach that may increase recanalization rates without compromising time to initiation of treatment...
  30. doi request reprint Utility of the anesthetic test dose to avoid catastrophic injury during cervical transforaminal epidural injections
    Matthew Smuck
    Department of Orthopaedic Surgery, Stanford University, Redwood City, CA 94062, USA
    Spine J 10:857-64. 2010
    ..Routine use of the anesthetic test dose is one such method. The utility of the anesthetic test dose in this function has not been characterized in the current literature...
  31. pmc Cost-effectiveness of tissue-type plasminogen activator in the 3- to 4.5-hour time window for acute ischemic stroke
    Christie E Tung
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305 5235, USA
    Stroke 42:2257-62. 2011
    ..The aim of this study was to determine the cost-effectiveness of tissue-type plasminogen activator (tPA) treatment in the 3- to 4.5-hour time window after ischemic stroke...
  32. pmc Capsular warning syndrome caused by middle cerebral artery stenosis
    Jun Lee
    Department Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, 701 Welch Road, Suite 325, Palo Alto, Stanford, CA 94304, USA
    J Neurol Sci 296:115-20. 2010
    ..In select cases intracranial angioplasty, may be an effective treatment for patients with capsular warning syndrome...
  33. pmc A comparison of cooling techniques to treat cardiac arrest patients with hypothermia
    Anna Finley Caulfield
    Stanford Neurocritical Care Program, Stanford Stroke Center, Stanford University School of Medicine Center, Palo Alto, CA 94304, USA
    Stroke Res Treat 2011:690506. 2011
    ..8-6.2) and 4.5 (IQR, 3-6.5) hours, respectively (P = .67). Adverse events were similar. Conclusion. Endovascular cooling maintains target temperatures better than conventional surface cooling...
  34. doi request reprint Optimal outcome measures for detecting clinical benefits of early reperfusion: insights from the DEFUSE Study
    Wataru Kakuda
    Department of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, Japan
    J Stroke Cerebrovasc Dis 17:235-40. 2008
    ..There is no consensus regarding which clinical outcome scales are the most sensitive indicators of early reperfusion in patients with acute stroke...
  35. doi request reprint Optimal definition for PWI/DWI mismatch in acute ischemic stroke patients
    Wataru Kakuda
    Department of Rehabilitation Medicine, Jikei University School of Medicine, Minato ku, Tokyo, Japan
    J Cereb Blood Flow Metab 28:887-91. 2008
    ..Defining mismatch with a larger PWI/DWI ratio may provide greater power for detecting beneficial effects of reperfusion...
  36. ncbi request reprint Risk for symptomatic intracerebral hemorrhage after thrombolysis assessed by diffusion-weighted magnetic resonance imaging
    Oliver C Singer
    Klinik fur Neurologie, Universitatsklinik, Johann Wolfgang von Goethe Universität, Frankfurt, Germany
    Ann Neurol 63:52-60. 2008
    ..Here, we investigated the relation between pretreatment DWI lesion size and the risk for sICH after thrombolysis...
  37. ncbi request reprint Thyroid replacement therapy and atrial fibrillation in acute ischemic stroke
    MARTIN J O'DONNELL
    Henderson Research Center, McMaster University, Hamilton, Ontario, Canada
    Neurology 67:1714-5. 2006

Research Grants2

  1. Who Benefits from tPA 3-6 hours after Stroke
    Maarten Lansberg; Fiscal Year: 2007
    ..They will provide guidance throughout the award period and facilitate his transition into a successful independent investigator. ..