Annette Langer-Gould

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Late pregnancy suppresses relapses in experimental autoimmune encephalomyelitis: evidence for a suppressive pregnancy-related serum factor
    Annette Langer-Gould
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Immunol 169:1084-91. 2002
  2. doi request reprint Interferon-gamma-producing T cells, pregnancy, and postpartum relapses of multiple sclerosis
    Annette Langer-Gould
    Department of Health Research and Policy, School of Medicine, Stanford University, Stanford, CA 94305, USA
    Arch Neurol 67:51-7. 2010
  3. doi request reprint Exclusive breastfeeding and the risk of postpartum relapses in women with multiple sclerosis
    Annette Langer-Gould
    Stanford University School of Medicine, HRP Redwood Bldg, Room T202 MC 5405, Stanford, CA 94305, USA
    Arch Neurol 66:958-63. 2009
  4. ncbi request reprint Clinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review
    Annette Langer-Gould
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA
    Arch Neurol 63:1686-91. 2006
  5. ncbi request reprint Progressive multifocal leukoencephalopathy and multiple sclerosis: lessons from natalizumab
    Annette Langer-Gould
    Stanford University School of Medicine, HRP Redwood Building, Room T202, MC 5405, Stanford, CA 94305, USA
    Curr Neurol Neurosci Rep 6:253-8. 2006
  6. ncbi request reprint Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
    Annette Langer-Gould
    Department of Neurology, Stanford University School of Medicine, Stanford, Calif, USA
    N Engl J Med 353:375-81. 2005
  7. ncbi request reprint Strategies for managing the side effects of treatments for multiple sclerosis
    Annette Langer-Gould
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Hospital and Clinic, Stanford, California, USA
    Neurology 63:S35-41. 2004
  8. ncbi request reprint What went wrong in the natalizumab trials?
    Annette Langer-Gould
    Department of Health Research and Policy, Stanford University School of Medicine, CA94305, USA
    Lancet 367:708-10. 2006
  9. doi request reprint B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
    Stephen L Hauser
    Department of Neurology, University of California at San Francisco, San Francisco, CA 94143 0114, USA
    N Engl J Med 358:676-88. 2008
  10. doi request reprint Absence of neuromyelitis optica IgG antibody in an active relapsing-remitting multiple sclerosis population
    Craig H Smith
    Genentech Corporation CHS, South San Francisco, California, USA
    J Neuroophthalmol 29:104-6. 2009

Research Grants

  1. Pregnancy and the Modulation of Multiple Sclerosis
    Annette Langer Gould; Fiscal Year: 2006

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Late pregnancy suppresses relapses in experimental autoimmune encephalomyelitis: evidence for a suppressive pregnancy-related serum factor
    Annette Langer-Gould
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Immunol 169:1084-91. 2002
    ..In conclusion, serum from late pregnancy has the capacity to down-regulate T cell responses and might be associated with the amelioration of disease activity in experimental autoimmune encephalomyelitis...
  2. doi request reprint Interferon-gamma-producing T cells, pregnancy, and postpartum relapses of multiple sclerosis
    Annette Langer-Gould
    Department of Health Research and Policy, School of Medicine, Stanford University, Stanford, CA 94305, USA
    Arch Neurol 67:51-7. 2010
    ..To determine whether fluctuations in functional T-cell subsets can explain why multiple sclerosis (MS) relapses decline during pregnancy and increase in the postpartum period...
  3. doi request reprint Exclusive breastfeeding and the risk of postpartum relapses in women with multiple sclerosis
    Annette Langer-Gould
    Stanford University School of Medicine, HRP Redwood Bldg, Room T202 MC 5405, Stanford, CA 94305, USA
    Arch Neurol 66:958-63. 2009
    ..To determine if exclusive breastfeeding protects against postpartum relapses of multiple sclerosis (MS) and, if so, whether this protection is related to prolonged lactational amenorrhea...
  4. ncbi request reprint Clinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review
    Annette Langer-Gould
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA
    Arch Neurol 63:1686-91. 2006
    ..To identify clinical and demographic factors associated with long-term disability in patients with relapsing-remitting multiple sclerosis...
  5. ncbi request reprint Progressive multifocal leukoencephalopathy and multiple sclerosis: lessons from natalizumab
    Annette Langer-Gould
    Stanford University School of Medicine, HRP Redwood Building, Room T202, MC 5405, Stanford, CA 94305, USA
    Curr Neurol Neurosci Rep 6:253-8. 2006
    ..Finally, we discuss what additional natalizumab efficacy data need to be presented before any decisions should be made about treating RRMS patients with a high risk of developing long-term disability...
  6. ncbi request reprint Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
    Annette Langer-Gould
    Department of Neurology, Stanford University School of Medicine, Stanford, Calif, USA
    N Engl J Med 353:375-81. 2005
    ..The patient was treated with systemic cytarabine, and two months later, his condition had improved...
  7. ncbi request reprint Strategies for managing the side effects of treatments for multiple sclerosis
    Annette Langer-Gould
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Hospital and Clinic, Stanford, California, USA
    Neurology 63:S35-41. 2004
    ..Patients should be encouraged to communicate with their physicians so that side effects can be managed promptly. This article describes and provides management strategies for side effects associated with MS treatments...
  8. ncbi request reprint What went wrong in the natalizumab trials?
    Annette Langer-Gould
    Department of Health Research and Policy, Stanford University School of Medicine, CA94305, USA
    Lancet 367:708-10. 2006
  9. doi request reprint B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
    Stephen L Hauser
    Department of Neurology, University of California at San Francisco, San Francisco, CA 94143 0114, USA
    N Engl J Med 358:676-88. 2008
    ..There is increasing evidence that B lymphocytes are involved in the pathogenesis of multiple sclerosis, and they may be a therapeutic target. Rituximab, a monoclonal antibody, selectively targets and depletes CD20+ B lymphocytes...
  10. doi request reprint Absence of neuromyelitis optica IgG antibody in an active relapsing-remitting multiple sclerosis population
    Craig H Smith
    Genentech Corporation CHS, South San Francisco, California, USA
    J Neuroophthalmol 29:104-6. 2009
    ..We resolved to test for NMO antibody in a population of patients with active relapsing-remitting (RR) MS...
  11. ncbi request reprint Gray matter N-acetyl aspartate deficits in secondary progressive but not relapsing-remitting multiple sclerosis
    Elfar Adalsteinsson
    Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA
    AJNR Am J Neuroradiol 24:1941-5. 2003
    ....
  12. ncbi request reprint Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
    Christopher Lock
    Department of Neurology and Neurological Sciences, Beckman Center, Stanford University, Stanford, California, USA
    Nat Med 8:500-8. 2002
    ..These results in EAE corroborate the microarray studies on MS lesions. Large-scale analysis of transcripts in MS lesions elucidates new aspects of pathology and opens possibilities for therapy...

Research Grants1

  1. Pregnancy and the Modulation of Multiple Sclerosis
    Annette Langer Gould; Fiscal Year: 2006
    ..The search for the pregnancy-related factor or hormone responsible for the protective effect of pregnancy in MS may potentially lead to the development of novel treatments for MS and other Th1-driven autoimmune diseases. ..