Eswar Krishnan

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Hyperuricemia and incidence of hypertension among men without metabolic syndrome
    Eswar Krishnan
    School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 49:298-303. 2007
  2. pmc Gout and the risk for incident heart failure and systolic dysfunction
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
    BMJ Open 2:e000282. 2012
  3. pmc Dutch translation and cross-cultural adaptation of the PROMISĀ® physical function item bank and cognitive pre-test in Dutch arthritis patients
    Martijn Ah Oude Voshaar
    Institute for Behavioural Research, University of Twente, Drienerlolaan 5, Enschede, 7522 NB, The Netherlands
    Arthritis Res Ther 14:R47. 2012
  4. pmc Reduced glomerular function and prevalence of gout: NHANES 2009-10
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA
    PLoS ONE 7:e50046. 2012
  5. doi request reprint Hyperuricemia in young adults and risk of insulin resistance, prediabetes, and diabetes: a 15-year follow-up study
    Eswar Krishnan
    Department of Medicine, School of Medicine, Stanford University, Palo Alto, California, USA
    Am J Epidemiol 176:108-16. 2012
  6. pmc Hyperuricemia and untreated gout are poor prognostic markers among those with a recent acute myocardial infarction
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, 1000 Welch Rd, Suite 203, Palo Alto, CA 94304, USA
    Arthritis Res Ther 14:R10. 2012
  7. doi request reprint Hyperuricemia and the echocardiographic measures of myocardial dysfunction
    Eswar Krishnan
    Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Congest Heart Fail 18:138-43. 2012
  8. doi request reprint Nature versus nurture in gout: a twin study
    Eswar Krishnan
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA
    Am J Med 125:499-504. 2012
  9. ncbi request reprint Inflammation, oxidative stress and lipids: the risk triad for atherosclerosis in gout
    Eswar Krishnan
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA
    Rheumatology (Oxford) 49:1229-38. 2010
  10. doi request reprint Uric acid in heart disease: a new C-reactive protein?
    Eswar Krishnan
    Stanford University School of Medicine, Stanford, California, USA
    Curr Opin Rheumatol 23:174-7. 2011

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Hyperuricemia and incidence of hypertension among men without metabolic syndrome
    Eswar Krishnan
    School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 49:298-303. 2007
    ..09; 95% CI: 1.02 to 1.17). We conclude that the hyperuricemia-hypertension risk relationship is present among normotensive middle-aged men without diabetes/glucose intolerance or metabolic syndrome...
  2. pmc Gout and the risk for incident heart failure and systolic dysfunction
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
    BMJ Open 2:e000282. 2012
    ..To test the hypothesis that gouty arthritis (gout) is a risk factor for incidence of heart failure and for echocardiographic measures signifying subclinical heart failure...
  3. pmc Dutch translation and cross-cultural adaptation of the PROMISĀ® physical function item bank and cognitive pre-test in Dutch arthritis patients
    Martijn Ah Oude Voshaar
    Institute for Behavioural Research, University of Twente, Drienerlolaan 5, Enschede, 7522 NB, The Netherlands
    Arthritis Res Ther 14:R47. 2012
    ..The aim of this study was to translate and cross-culturally adapt the PROMIS physical function item bank to the Dutch language and to pretest it in a sample of patients with arthritis...
  4. pmc Reduced glomerular function and prevalence of gout: NHANES 2009-10
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA
    PLoS ONE 7:e50046. 2012
    ..The objective of the present study was to estimate prevalence of gout and hyperuricemia among people with impaired GFR in the US general population...
  5. doi request reprint Hyperuricemia in young adults and risk of insulin resistance, prediabetes, and diabetes: a 15-year follow-up study
    Eswar Krishnan
    Department of Medicine, School of Medicine, Stanford University, Palo Alto, California, USA
    Am J Epidemiol 176:108-16. 2012
    ..This observation was generally consistent across subgroups. The authors conclude that hyperuricemia in the midtwenties is an independent marker for predicting diabetes and prediabetes among young adults in the subsequent 15 years...
  6. pmc Hyperuricemia and untreated gout are poor prognostic markers among those with a recent acute myocardial infarction
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, 1000 Welch Rd, Suite 203, Palo Alto, CA 94304, USA
    Arthritis Res Ther 14:R10. 2012
    ..The purpose of this study was to assess hyperuricemia as a biomarker of CHD outcomes in such patients...
  7. doi request reprint Hyperuricemia and the echocardiographic measures of myocardial dysfunction
    Eswar Krishnan
    Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Congest Heart Fail 18:138-43. 2012
    ..604) for abnormal LV ejection fraction and 4.584 (95% confidence interval, 1.951-10.768) for LV systolic dysfunction compared with those in the lowest quartile. Hyperuricemia in young adults can be a marker for subsequent heart failure...
  8. doi request reprint Nature versus nurture in gout: a twin study
    Eswar Krishnan
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA
    Am J Med 125:499-504. 2012
    ..Some rare forms of gout have a known genetic basis, but the relative importance of genetic factors on the risk for the lifetime prevalence of gout is not clear...
  9. ncbi request reprint Inflammation, oxidative stress and lipids: the risk triad for atherosclerosis in gout
    Eswar Krishnan
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA
    Rheumatology (Oxford) 49:1229-38. 2010
    ..It is hoped that the introduction of newer urate-lowering agents may help to clarify this picture and improve treatment options for both gout and atherosclerosis...
  10. doi request reprint Uric acid in heart disease: a new C-reactive protein?
    Eswar Krishnan
    Stanford University School of Medicine, Stanford, California, USA
    Curr Opin Rheumatol 23:174-7. 2011
    ....
  11. pmc Hyperuricemia and incident heart failure
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Circ Heart Fail 2:556-62. 2009
    ..However, the relationship between hyperuricemia and the risk for incidence of heart failure in a community-based population has not been studied...
  12. pmc Hyperuricemia and the risk for subclinical coronary atherosclerosis--data from a prospective observational cohort study
    Eswar Krishnan
    Department of Medicine, Stanford University School of Medicine, 1000 Welch Road, Suite 203, Palo Alto, CA 94304, USA
    Arthritis Res Ther 13:R66. 2011
    ....
  13. ncbi request reprint Long-term cardiovascular mortality among middle-aged men with gout
    Eswar Krishnan
    Division of Rheumatology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Arch Intern Med 168:1104-10. 2008
    ..There are limited data available on the association of gouty arthritis (gout) in middle age with long-term cardiovascular disease (CVD) mortality...
  14. doi request reprint Disability in rheumatoid arthritis in the era of biological treatments
    Eswar Krishnan
    Division of Rheumatology and Immunology, Stanford University Department of Medicine, Palo Alto, CA 94304, USA
    Ann Rheum Dis 71:213-8. 2012
    ..Rheumatoid arthritis (RA) is a disabling disease. The authors studied the impact of new, expensive and occasionally toxic biological treatments on disability outcomes in real-world populations of patients with RA...
  15. doi request reprint Atherosclerotic cardiovascular disease in hospitalized patients with systemic sclerosis: higher mortality than patients with lupus and rheumatoid arthritis
    Amish J Dave
    Stanford University School of Medicine, Palo Alto, California
    Arthritis Care Res (Hoboken) 66:323-7. 2014
    ..We utilized the US Nationwide Inpatient Sample to assess the frequency of and mortality risk associated with ASCVD among hospitalized SSc patients...
  16. doi request reprint Serum urate and incidence of kidney disease among veterans with gout
    Eswar Krishnan
    Stanford University, Stanford, California Takeda Pharmaceuticals International Inc, Deerfield, Illinois, USA
    J Rheumatol 40:1166-72. 2013
    ..To study the association between serum urate level (sUA) and the risk of incident kidney disease among US veterans with gouty arthritis...
  17. ncbi request reprint Declines in mortality from acute myocardial infarction in successive incidence and birth cohorts of patients with rheumatoid arthritis
    Eswar Krishnan
    Stanford University, Division of Immunology, Department of Medicine, 1000 Welch Rd, Suite 203, Palo Alto, Calif, USA
    Circulation 110:1774-9. 2004
    ..The impact of this on atherosclerotic cardiovascular diseases is not known...
  18. ncbi request reprint Serum uric acid level and risk for peripheral arterial disease: analysis of data from the multiple risk factor intervention trial
    Joshua F Baker
    Department of Medicine, University of Pennsylvania, USA
    Angiology 58:450-7. 2007
    ..A history of gouty arthritis is an independent and statistically significant predictor of incidence of PAD even after adjustment for the effect of underlying hyperuricemia...
  19. pmc Extending the floor and the ceiling for assessment of physical function
    James F Fries
    Stanford University, Palo Alto, California
    Arthritis Rheumatol 66:1378-87. 2014
    ..e., subjects with extremely poor function ["floor"] or extremely good health ["ceiling"])...
  20. ncbi request reprint Low-level lead exposure and the prevalence of gout: an observational study
    Eswar Krishnan
    Stanford University School of Medicine, 1000 Welch Road, Suite 203, Palo Alto, CA 94304, USA
    Ann Intern Med 157:233-41. 2012
    ..Lead toxicity can lead to gouty arthritis (gout), but whether the low lead exposure in the contemporary general population confers risk for gout is not known...
  21. pmc Muscle strength, mass, and quality in older men and women with knee osteoarthritis
    Molly B Conroy
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Arthritis Care Res (Hoboken) 64:15-21. 2012
    ..To examine the relationship between knee osteoarthritis (OA) and muscle parameters in a biracial cohort of older adults...
  22. ncbi request reprint Chronic kidney disease and the risk of incident gout among middle-aged men: a seven-year prospective observational study
    Eswar Krishnan
    Stanford University School of Medicine, Stanford, California
    Arthritis Rheum 65:3271-8. 2013
    ..Surprisingly, few studies have assessed whether a reduced glomerular filtration rate (GFR) and/or kidney damage is associated with a higher incidence of gout, and this study was undertaken to address this question...
  23. pmc Improved responsiveness and reduced sample size requirements of PROMIS physical function scales with item response theory
    James F Fries
    Department of Medicine, Stanford University School of Medicine, 1000 Welch Road, Suite 203, Palo Alto, CA 04304, USA
    Arthritis Res Ther 13:R147. 2011
    ..We compared the ability to detect change in physical function using original (Legacy) instruments with Item-Improved and PROMIS IRT-based instruments...
  24. ncbi request reprint Primary knee and hip arthroplasty among nonagenarians and centenarians in the United States
    Eswar Krishnan
    University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 57:1038-42. 2007
    ..This report focuses on the poorly studied epidemiology and mortality outcomes of arthroplasty among these individuals...
  25. ncbi request reprint Gout and the risk of acute myocardial infarction
    Eswar Krishnan
    University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 54:2688-96. 2006
    ....
  26. ncbi request reprint Patient questionnaires and formal education level as prospective predictors of mortality over 10 years in 97% of 1416 patients with rheumatoid arthritis from 15 United States private practices
    Theodore Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 4500, USA
    J Rheumatol 31:229-34. 2004
    ....
  27. doi request reprint Progress in assessing physical function in arthritis: PROMIS short forms and computerized adaptive testing
    James F Fries
    Department of Medicine, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    J Rheumatol 36:2061-6. 2009
    ..IRT-based instruments can improve measurement precision substantially over a wider range of disease severity. These modern methods were applied and the magnitude of improvement was estimated...
  28. doi request reprint Pegloticase and the patient with treatment-failure gout
    Amish J Dave
    Department of Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    Expert Rev Clin Pharmacol 5:501-8. 2012
    ..Two recent Phase III trials have found pegloticase to be effective in the management of treatment-failure gout. These studies also highlight safety concerns regarding the drug's immunogenicity...
  29. pmc Factors associated with patients who leave acute-care hospitals against medical advice
    Said A Ibrahim
    Center for Health Equity Research and Promotion, Veterans Administration Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    Am J Public Health 97:2204-8. 2007
    ..We examined hospital- and patient-related factors associated with discharge against medical advice (termed self-discharge) after emergency admission to acute-care hospitals...
  30. ncbi request reprint Gout and coronary artery disease: epidemiologic clues
    Eswar Krishnan
    S709 BST South, 3500 Terrace Street, Pittsburgh, PA 15215, USA
    Curr Rheumatol Rep 10:249-55. 2008
    ..Although there are gaps in evidence pointing to a causative pathway, overall, evidence exists for a relationship between gouty arthritis and coronary artery disease independent of traditional risk factors...
  31. doi request reprint Systemic lupus erythematosus, rheumatoid arthritis, and postarthroplasty mortality: a cross-sectional analysis from the nationwide inpatient sample
    Robyn T Domsic
    Stanford University School of Medicine, Palo Alto, CA 94304, USA
    J Rheumatol 37:1467-72. 2010
    ..Systemic lupus erythematosus (SLE) is a disease of considerable morbidity, and this may place patients at greater risk for poor in-hospital postoperative outcomes for procedures such as arthroplasty. Our aim was to test this hypothesis...
  32. pmc The PROMIS of better outcome assessment: responsiveness, floor and ceiling effects, and Internet administration
    James Fries
    Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
    J Rheumatol 38:1759-64. 2011
    ..We present data on current progress in 3 crucial areas: floor and ceiling effects, responsiveness to change, and interactive computer-based administration over the Internet...
  33. ncbi request reprint Attrition bias in rheumatoid arthritis databanks: a case study of 6346 patients in 11 databanks and 65,649 administrations of the Health Assessment Questionnaire
    Eswar Krishnan
    Division of Rheumatology, Department of Medicine, Stanford University, Palo Alto, California, USA
    J Rheumatol 31:1320-6. 2004
    ..Patient dropout (attrition) can bias and threaten validity of databank-based studies. Although there are several databanks of rheumatoid arthritis (RA) in operation, this phenomenon has not been well studied...
  34. ncbi request reprint National databases and rheumatology research II: the National Health and Nutrition Examination Surveys
    Tuulikki Sokka
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, 203 Oxford House, Nashville, TN 37232 4500, USA
    Rheum Dis Clin North Am 30:869-78, viii. 2004
    ..This article describes features of the surveys and provides examples of research on musculoskeletal disorders that used the survey data...
  35. ncbi request reprint Serum uric acid and cardiovascular disease: recent developments, and where do they leave us?
    Joshua F Baker
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Med 118:816-26. 2005
    ..Trials of SUA-lowering therapy in hyperuricemic patients evaluating the effect on cardiovascular outcomes are justified in high-risk patients...
  36. doi request reprint An analysis of connective tissue disease-associated interstitial lung disease at a US Tertiary Care Center: better survival in patients with systemic sclerosis
    Robert Su
    Department of Medicine, Division of Immunology and Rheumatology, Division of Pulmonary and Critical Care, Stanford University School of Medicine, Palo Alto, CA, USA
    J Rheumatol 38:693-701. 2011
    ....
  37. ncbi request reprint Obstetric hospitalizations in the United States for women with systemic lupus erythematosus and rheumatoid arthritis
    Eliza F Chakravarty
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California, USA
    Arthritis Rheum 54:899-907. 2006
    ....
  38. ncbi request reprint Hospitalization and mortality of patients with systemic lupus erythematosus
    Eswar Krishnan
    Division of Rheumatology, Department of Medicine, University of Pittsburgh, Pennsylvania 15261, USA
    J Rheumatol 33:1770-4. 2006
    ..To describe hospitalization and mortality outcomes of patients with systemic lupus erythematosus (SLE) in the general population...
  39. ncbi request reprint Gout in ambulatory care settings in the United States
    Eswar Krishnan
    Division of Rheumatology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    J Rheumatol 35:498-501. 2008
    ..To describe the ambulatory care utilization by patients with gouty arthritis (gout) in the United States using a nationally representative sample...
  40. ncbi request reprint Gout and the heart
    Vidula Bhole
    515 Olmsted Road, Palo Alto, CA 94305, USA
    Rheum Dis Clin North Am 40:125-43. 2014
    ..Future studies are expected to shed light on the pathophysiologic basis of this association. ..
  41. pmc Brief report: citrullination within the atherosclerotic plaque: a potential target for the anti-citrullinated protein antibody response in rheumatoid arthritis
    Jeremy Sokolove
    Stanford University Medical Center, Stanford, CA, USA
    Arthritis Rheum 65:1719-24. 2013
    ..To investigate whether citrullinated proteins within the atherosclerotic plaque can be targeted by anti-citrullinated protein antibodies (ACPAs), forming stimulatory immune complexes that propagate the progression of atherosclerosis...
  42. ncbi request reprint Stroke subtypes among young patients with systemic lupus erythematosus
    Eswar Krishnan
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Med 118:1415. 2005
    ..Little is known about subtypes of stroke in lupus...
  43. ncbi request reprint Reduction in long-term functional disability in rheumatoid arthritis from 1977 to 1998:a longitudinal study of 3035 patients
    Eswar Krishnan
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California 94304, USA
    Am J Med 115:371-6. 2003
    ..We therefore assessed trends in disability over time in a large cohort of patients with rheumatoid arthritis...
  44. pmc Measuring effectiveness of drugs in observational databanks: promises and perils
    Eswar Krishnan
    Division of Immunology, Department of Medicine, Stanford University, Palo Alto, CA, USA
    Arthritis Res Ther 6:41-4. 2004
    ..An international metaRegister and a formal mechanism for standardizing and sharing drug data could help improve the utility of databanks. Medical journals have a vital role in enforcing a quality checklist that improves reporting...
  45. pmc Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development
    James F Fries
    Stanford University School of Medicine, Palo Alto, California, USA
    Arthritis Res Ther 6:R250-5. 2004
    ..We propose a principle of 'positive expected outcomes', which informs the assessment that a trial is ethical, together with a restatement of the priority of personal autonomy...
  46. ncbi request reprint Normative values for the Health Assessment Questionnaire disability index: benchmarking disability in the general population
    Eswar Krishnan
    Stanford University, Palo Alto, California, USA
    Arthritis Rheum 50:953-60. 2004
    ..This study was undertaken to establish normative values for the HAQ DI in a general population and to analyze its correlates...
  47. ncbi request reprint What constitutes progress in assessing patient outcomes?
    James F Fries
    Stanford University School of Medicine, Palo Alto, CA 94304, USA
    J Clin Epidemiol 62:779-80. 2009
    ..Another limitation is the degree of measurement error, the signal-to-noise ratio. These two issues drive down the statistical power of clinical trials and increase their expense...
  48. pmc Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
    Guangjin Li
    Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
    Nat Med 18:1518-24. 2012
    ..DUSP6 is a potential intervention target for restoring T cell responses in the elderly, which may augment the effectiveness of vaccination...
  49. ncbi request reprint Sleep-disordered breathing among women with fibromyalgia syndrome
    Mansi A Shah
    The Reading Hospital and Medical Center, West Reading, Pennsylvania, USA
    J Clin Rheumatol 12:277-81. 2006
    ..One reason for this is the lack of understanding how information from these studies could aid clinical decisions...
  50. pmc Smoking-gender interaction and risk for rheumatoid arthritis
    Eswar Krishnan
    Department of Medicine, Stanford University, Palo Alto, California, USA
    Arthritis Res Ther 5:R158-62. 2003
    ..We conclude that sex is a biologic effect modifier in the association between smoking and rheumatoid arthritis. The role of menopause in the etiology of rheumatoid arthritis merits further research...
  51. ncbi request reprint Disease-related and all-cause health care costs of elderly patients with gout
    Eric Q Wu
    Analysis Group, 111 Huntington Ave, 10th Fl, Boston, MA 02199, USA
    J Manag Care Pharm 14:164-75. 2008
    ..Older adults with gout are of particular interest because they tend to experience higher rates of tophi, an advanced stage of gout, than do younger patients...
  52. ncbi request reprint Early and extensive erosiveness in peripheral joints predicts atlantoaxial subluxations in patients with rheumatoid arthritis
    Marko Henrik Neva
    Division of Orthopaedic and Trauma Surgery, Department of Surgery, Tampere University Hospital, Tampere, Finland
    Arthritis Rheum 48:1808-13. 2003
    ..e., vertical subluxation) in patients with rheumatoid arthritis (RA) who were treated early and continuously with disease-modifying antirheumatic drugs for 8-13 years...
  53. ncbi request reprint Smoking, gender and rheumatoid arthritis-epidemiological clues to etiology. Results from the behavioral risk factor surveillance system
    Eswar Krishnan
    Clinical Research Center of Reading, 401 Buttonwood St, West Reading, PA 19611, USA
    Joint Bone Spine 70:496-502. 2003
    ..This study was undertaken to confirm and extend our earlier observation that gender is a biological effect modifier of smoking-rheumatoid arthritis (RA) relationship in a diverse national survey sample in the United States...
  54. pmc Percentile benchmarks in patients with rheumatoid arthritis: Health Assessment Questionnaire as a quality indicator (QI)
    Eswar Krishnan
    Clinical Research Center of Reading, West Reading, PA, USA
    Arthritis Res Ther 6:R505-13. 2004
    ....
  55. ncbi request reprint Functional disability in rheumatoid arthritis patients compared with a community population in Finland
    Tuulikki Sokka
    Jyvaskyla Central Hospital, Jyvaskyla, Finland
    Arthritis Rheum 48:59-63. 2003
    ..To compare Health Assessment Questionnaire (HAQ) scores of patients with rheumatoid arthritis (RA) with HAQ scores from a sex- and age-adjusted population...
  56. pmc Unregistered trials are unethical
    Eswar Krishnan
    PLoS Med 2:e48. 2005
  57. ncbi request reprint Rheumatoid arthritis: radiographic progression is getting milder
    Eswar Krishnan
    J Rheumatol 32:195; author reply 195. 2005