Albert Koong

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc ACR appropriateness criteria®  resectable rectal cancer
    William E Jones
    UT Health Science Center San Antonio, San Antonio, Texas, USA
    Radiat Oncol 7:161. 2012
  2. pmc Orthovoltage intraoperative radiation therapy for pancreatic adenocarcinoma
    Pavan Bachireddy
    Department of Radiation Oncology, Stanford Cancer Center, Stanford University, Stanford, CA, USA
    Radiat Oncol 5:105. 2010
  3. pmc Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis
    Stephanie T Chang
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA
    J Transl Med 7:105. 2009
  4. ncbi request reprint Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer
    Albert C Koong
    Department of Radiation Oncology, Stanford University School of Medicine, 269 Campus Drive West, Stanford, CA 94305
    Int J Radiat Oncol Biol Phys 63:320-3. 2005
  5. ncbi request reprint Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer
    Albert C Koong
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5152, USA
    Int J Radiat Oncol Biol Phys 58:1017-21. 2004
  6. ncbi request reprint Targeting XBP-1 as a novel anti-cancer strategy
    Albert C Koong
    Stanford University, Department of Radiation Oncology, CA 94305 5152, USA
    Cancer Biol Ther 5:756-9. 2006
  7. doi request reprint Intrafraction verification of gated RapidArc by using beam-level kilovoltage X-ray images
    Ruijiang Li
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California
    Int J Radiat Oncol Biol Phys 83:e709-15. 2012
  8. ncbi request reprint Mature results from a randomized Phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Cancer 106:1940-9. 2006
  9. pmc The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth
    Kevin L Bennewith
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    Cancer Res 69:775-84. 2009
  10. pmc In vivo 1H magnetic resonance spectroscopy of lactate in patients with stage IV head and neck squamous cell carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 71:1151-7. 2008

Research Grants

Detail Information

Publications55

  1. pmc ACR appropriateness criteria®  resectable rectal cancer
    William E Jones
    UT Health Science Center San Antonio, San Antonio, Texas, USA
    Radiat Oncol 7:161. 2012
    ..In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment...
  2. pmc Orthovoltage intraoperative radiation therapy for pancreatic adenocarcinoma
    Pavan Bachireddy
    Department of Radiation Oncology, Stanford Cancer Center, Stanford University, Stanford, CA, USA
    Radiat Oncol 5:105. 2010
    ..To analyze the outcomes of patients from a single institution treated with surgery and orthovoltage intraoperative radiotherapy (IORT) for pancreatic adenocarcinoma...
  3. pmc Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis
    Stephanie T Chang
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA
    J Transl Med 7:105. 2009
    ..Proximity ligation assay (PLA) is a highly sensitive technique for multiplex detection of biomarkers in plasma with little or no interfering background signal...
  4. ncbi request reprint Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer
    Albert C Koong
    Department of Radiation Oncology, Stanford University School of Medicine, 269 Campus Drive West, Stanford, CA 94305
    Int J Radiat Oncol Biol Phys 63:320-3. 2005
    ..To determine the efficacy of concurrent 5-fluorouracil (5-FU) and intensity-modulated radiotherapy (IMRT) followed by body stereotactic radiosurgery (SRS) in patients with locally advanced pancreatic cancer...
  5. ncbi request reprint Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer
    Albert C Koong
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5152, USA
    Int J Radiat Oncol Biol Phys 58:1017-21. 2004
    ..To determine the feasibility and toxicity of delivering stereotactic radiosurgery to patients with locally advanced pancreatic cancer...
  6. ncbi request reprint Targeting XBP-1 as a novel anti-cancer strategy
    Albert C Koong
    Stanford University, Department of Radiation Oncology, CA 94305 5152, USA
    Cancer Biol Ther 5:756-9. 2006
    ..This review focuses on the role of the IRE1-XBP1 branch of the UPR and its role in mediating cell survival and tumor growth. Inhibition of this pathway will be discussed as a therapeutic strategy...
  7. doi request reprint Intrafraction verification of gated RapidArc by using beam-level kilovoltage X-ray images
    Ruijiang Li
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California
    Int J Radiat Oncol Biol Phys 83:e709-15. 2012
    ..To verify the geometric accuracy of gated RapidArc treatment using kV images acquired during dose delivery...
  8. ncbi request reprint Mature results from a randomized Phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Cancer 106:1940-9. 2006
    ....
  9. pmc The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth
    Kevin L Bennewith
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    Cancer Res 69:775-84. 2009
    ....
  10. pmc In vivo 1H magnetic resonance spectroscopy of lactate in patients with stage IV head and neck squamous cell carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 71:1151-7. 2008
    ..To investigate in vivo(1)H magnetic resonance spectroscopy imaging of lactate for assessing tumor hypoxia in head and neck cancers and to determine its utility in predicting the response and outcomes...
  11. doi request reprint Automated contour mapping with a regional deformable model
    Ming Chao
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 70:599-608. 2008
    ..To develop a regional narrow-band algorithm to auto-propagate the contour surface of a region of interest (ROI) from one phase to other phases of four-dimensional computed tomography (4D-CT)...
  12. ncbi request reprint Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma
    Megan E Daly
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, California 94305, USA
    Head Neck 29:211-20. 2007
    ....
  13. ncbi request reprint Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5302, USA
    Int J Radiat Oncol Biol Phys 56:1046-54. 2003
    ..Stereotactic radiosurgery (STR) was used to boost the tumor site after EBRT to improve local control...
  14. ncbi request reprint Four-dimensional cone-beam computed tomography using an on-board imager
    Tianfang Li
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA
    Med Phys 33:3825-33. 2006
    ....
  15. pmc Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
    Janine T Erler
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Cancer Cell 15:35-44. 2009
    ..CD11b+ cells and LOX also colocalize in biopsies of human metastases. Our findings demonstrate a critical role for LOX in premetastatic niche formation and support targeting LOX for the treatment and prevention of metastatic disease...
  16. pmc The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas
    Christina S Kong
    Department of Pathology, Stanford University, Santa Cruz, CA, USA
    Int J Radiat Oncol Biol Phys 74:553-61. 2009
    ....
  17. doi request reprint EUS-guided gold fiducial insertion for image-guided radiation therapy of pancreatic cancer: 50 successful cases without fluoroscopy
    Walter G Park
    Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA
    Gastrointest Endosc 71:513-8. 2010
    ..Application of IGRT to unresectable pancreatic cancer requires the use of fiducials to track the precise location of the tumor. Fiducial markers have been successfully placed endoscopically...
  18. ncbi request reprint Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer
    Vivek K Mehta
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA, USA
    Int J Radiat Oncol Biol Phys 55:132-7. 2003
    ..We report the results from a Phase II trial of preoperative radiotherapy (RT), CPT-11, and 5-FU for patients with ultrasound-staged T3 rectal cancer...
  19. pmc Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect
    Yijun Chen
    Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 4:e7033. 2009
    ....
  20. pmc A novel aldehyde dehydrogenase-3 activator (Alda-89) protects submandibular gland function from irradiation without accelerating tumor growth
    Nan Xiao
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA
    Clin Cancer Res 19:4455-64. 2013
    ....
  21. doi request reprint Seventh edition (2010) of the AJCC/UICC staging system for gastric adenocarcinoma: is there room for improvement?
    Manali I Patel
    Department of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA, USA
    Ann Surg Oncol 20:1631-8. 2013
    ..We sought to validate the new system on a U.S. population database...
  22. ncbi request reprint Reducing respiratory motion artifacts in positron emission tomography through retrospective stacking
    Brian Thorndyke
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA
    Med Phys 33:2632-41. 2006
    ..These phantom and patient studies demonstrate that RS can correct for lesion motion and deformation, while substantially improving tumor visibility and background noise...
  23. ncbi request reprint Cone beam CT imaging with limited angle of projections and prior knowledge for volumetric verification of non-coplanar beam radiation therapy: a proof of concept study
    Bowen Meng
    Electrical Engineering Department, Stanford University, Stanford, CA 94305, USA Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA
    Phys Med Biol 58:7777-89. 2013
    ..In this proof of concept study, non-coplanar beams with couch rotations of 45° can be effectively verified with the CBCT technique. ..
  24. ncbi request reprint Enhanced 4D cone-beam CT with inter-phase motion model
    Tianfang Li
    Department of Radiation Oncology, Stanford University School of Medicine, Clinical Cancer Center, 875 Blake Wilbur Drive, Stanford, California 94305 5847, USA
    Med Phys 34:3688-95. 2007
    ..Several strategies of the motion derivation are discussed, and the resultant images are assessed with numerical simulations as well as a clinical case...
  25. ncbi request reprint Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 56:375-83. 2003
    ..To compare the Eppendorf PO2 histograph and the alkaline comet assay as methods of measuring tumor hypoxia in patients with head-and-neck squamous cell carcinomas...
  26. pmc Evaluation of the geometric accuracy of surrogate-based gated VMAT using intrafraction kilovoltage x-ray images
    Ruijiang Li
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
    Med Phys 39:2686-93. 2012
    ..To evaluate the geometric accuracy of beam targeting in external surrogate-based gated volumetric modulated arc therapy (VMAT) using kilovoltage (kV) x-ray images acquired during dose delivery...
  27. pmc First study of on-treatment volumetric imaging during respiratory gated VMAT
    Kihwan Choi
    Department of Electrical Engineering, Stanford University, Stanford, California 94305 and Department of Radiation Oncology, Stanford University, Stanford, California 94305
    Med Phys 40:040701. 2013
    ..This anatomical information may be valuable for geometric verification and treatment guidance, and useful for verification of treatment dose delivery, accumulation, and adaptation in the future...
  28. ncbi request reprint Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody
    Weibo Cai
    The Molecular Imaging Program at Stanford MIPS, Department of Radiology and Bio X Program, Stanford University School of Medicine, 1201 Welch Rd P095, Stanford, CA 94305 5484, USA
    Eur J Nucl Med Mol Imaging 34:850-8. 2007
    ..Here we report for the first time the quantitative positron emission tomography (PET) imaging of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab...
  29. pmc Impaired interferon signaling is a common immune defect in human cancer
    Rebecca J Critchley-Thorne
    Division of Hematology, Department of Medicine, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 106:9010-5. 2009
    ....
  30. ncbi request reprint Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms
    Catherine K Su
    Department of Radiation Oncology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5302, USA
    Int J Radiat Oncol Biol Phys 60:171-7. 2004
    ..In a single-institution, double-blind, prospective, randomized trial, we determined whether oral aloe vera gel can reduce radiation-induced mucositis in head-and-neck cancer patients...
  31. doi request reprint Safety and efficacy of percutaneous fiducial marker implantation for image-guided radiation therapy
    Nishita Kothary
    Division of Interventional Radiology, Stanford University Medical Center, 300 Pasteur Dr, H3652, Stanford, CA 94305 5642, USA
    J Vasc Interv Radiol 20:235-9. 2009
    ..To evaluate the safety and technical success rate of percutaneous fiducial marker implantation in preparation for image-guided radiation therapy...
  32. ncbi request reprint Sample classification from protein mass spectrometry, by 'peak probability contrasts'
    Robert Tibshirani
    Department of Health, Research and Policy, Stanford University, CA 94305, USA
    Bioinformatics 20:3034-44. 2004
    ..We illustrate the method on matrix-assisted laser desorption and ionization mass spectrometry data from a study of ovarian cancers...
  33. pmc ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
    Lori S Hart
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 5156, USA
    J Clin Invest 122:4621-34. 2012
    ..Our findings establish a role for UPR as an enhancer of c-Myc-induced transformation and suggest that UPR inhibition may be particularly effective against malignancies characterized by c-Myc overexpression...
  34. ncbi request reprint Overview of image-guided radiation therapy
    Lei Xing
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
    Med Dosim 31:91-112. 2006
    ..We introduce various new IGRT concepts and approaches, and hope to provide the reader with a comprehensive understanding of the emerging clinical IGRT technologies. Some important research topics will also be addressed...
  35. ncbi request reprint Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis
    Nadja Dornhöfer
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    Cancer Res 66:5816-27. 2006
    ..Together, these studies implicate CTGF as a new target in pancreatic cancer and suggest that inhibition of CTGF with a human monoclonal antibody may control primary and metastatic tumor growth...
  36. ncbi request reprint A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia
    Daniel W Nelson
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5847, USA
    Cancer Res 65:6151-8. 2005
    ..The 5HRE beta-hCG reporter system described here enables serial, noninvasive monitoring of tumor hypoxia in a mouse model by measuring a urinary reporter protein...
  37. ncbi request reprint Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer
    Yonghua Zhu
    Department of Radiation Oncology, 875 Blake Wilbur Dr, R CC G228, Stanford University, Stanford, CA 94305, USA
    Oncogene 24:6555-63. 2005
    ..Taken together, these results have identified a new hypoxia responsive transcriptional enhancer that is regulated by Akt signaling...
  38. ncbi request reprint Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling
    Yijun Chen
    Department of Radiation Oncology, Center for Clinical Sciences Research, Department of Surgery, Palo Alto VA Health Care System, Palo Alto, CA, USA
    Cancer Res 64:7302-10. 2004
    ..These data suggest that IKKbeta is a novel endogenous marker of tumor hypoxia and may represent a new target for anticancer therapy...
  39. ncbi request reprint XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
    Lorenzo Romero-Ramirez
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5152, USA
    Cancer Res 64:5943-7. 2004
    ..Taken together, these studies directly implicate XBP1 as an essential survival factor for hypoxic stress and tumor growth...
  40. ncbi request reprint Estimating DNA repair by sequential evaluation of head and neck tumor radiation sensitivity using the comet assay
    David J Terris
    Division of Otolaryngology Head and Neck Surgery, Stanford University Medical Center, R135, Edwards Bldg, Stanford, CA 94305 5328, USA
    Arch Otolaryngol Head Neck Surg 128:698-702. 2002
    ..The alkaline comet assay is a microelectrophoretic technique for detecting single-strand DNA breaks, and may be used as an indirect measure of hypoxia by determining the radiation sensitivity of individual cells...
  41. ncbi request reprint Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Center for Clinical Science Research South, Stanford, California 94305 5152, USA
    Clin Cancer Res 9:59-67. 2003
    ..Tumor hypoxia modifies treatment efficacy and promotes tumor progression. Here, we investigated the relationship between osteopontin (OPN), tumor pO(2), and prognosis in patients with head and neck squamous cell carcinomas (HNSCC)...
  42. ncbi request reprint Galectin-1: a link between tumor hypoxia and tumor immune privilege
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, 875 Blake Wilbur Drive, Stanford, CA 94305 5847, USA
    J Clin Oncol 23:8932-41. 2005
    ..To identify a 15-KDa novel hypoxia-induced secreted protein in head and neck squamous cell carcinomas (HNSCC) and to determine its role in malignant progression...
  43. ncbi request reprint The unfolded protein response: a novel component of the hypoxic stress response in tumors
    Douglas E Feldman
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305 5152, USA
    Mol Cancer Res 3:597-605. 2005
    ..Targeting various components of the UPR is a promising therapeutic strategy. Understanding the relationship between hypoxia, the UPR, and tumor growth is crucial to improving current cancer therapies...
  44. ncbi request reprint Multiplexed protein detection by proximity ligation for cancer biomarker validation
    Simon Fredriksson
    Stanford Genome Technology Center, Stanford, California 94305, USA
    Nat Methods 4:327-9. 2007
    ..The procedure can use a single polyclonal antibody batch for each target protein, simplifying affinity-reagent creation for new biomarker candidates...
  45. ncbi request reprint Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, California, USA
    J Thorac Oncol 1:802-9. 2006
    ..The purpose of this study was to report initial results of a phase I study using single-fraction stereotactic radiotherapy (RT) in patients with inoperable lung tumors...
  46. ncbi request reprint Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 69:167-75. 2007
    ..To investigate the expression pattern of hypoxia-induced proteins identified as being involved in malignant progression of head-and-neck squamous cell carcinoma (HNSCC) and to determine their relationship to tumor pO(2) and prognosis...
  47. pmc Amplification of tumor hypoxic responses by macrophage migration inhibitory factor-dependent hypoxia-inducible factor stabilization
    Millicent Winner
    Molecular Targets Program, James Graham Brown Cancer Center and Department of Radiation Oncology, University of Louisville, 580 South Preston Street, Louisville, KY, USA
    Cancer Res 67:186-93. 2007
    ..This functional interdependence between HIF-1alpha and MIF may represent an important and previously unrecognized pro-tumorigenic axis...
  48. ncbi request reprint Hypoxia and the unfolded protein response
    Constantinos Koumenis
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Methods Enzymol 435:275-93. 2007
    ....
  49. doi request reprint Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer
    Simon Fredriksson
    Stanford Genome Technology Center, Bio X, Stanford University, Stanford, CA, USA
    Clin Chem 54:582-9. 2008
    ..Sensitive methods are needed for biomarker discovery and validation. We tested one promising technology, multiplex proximity ligation assay (PLA), in a pilot study profiling plasma biomarkers in pancreatic and ovarian cancer...
  50. ncbi request reprint Plasma osteopontin is an independent prognostic marker for head and neck cancers
    David Petrik
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    J Clin Oncol 24:5291-7. 2006
    ..To confirm the relationship between plasma osteopontin (OPN) levels and treatment outcomes in head and neck squamous cell carcinoma (HNSCC) patients in an expanded study...
  51. ncbi request reprint High-dose single-fraction radiotherapy: exploiting a new biology?
    J Martin Brown
    Int J Radiat Oncol Biol Phys 71:324-5. 2008
  52. ncbi request reprint An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers
    Quynh Thu Le
    Department of Radiation Oncology, Stanford University Medical Center, Stanford, California 94305 5847, USA
    Clin Cancer Res 12:1507-14. 2006
    ..To directly assess tumor oxygenation in resectable non-small cell lung cancers (NSCLC) and to correlate tumor pO2 and the selected gene and protein expression to treatment outcomes...
  53. ncbi request reprint The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers
    Scott G Soltys
    Department of Radiation Oncology, and Health Policy and Research, Stanford University, Stanford, California 94305 5847, USA
    Clin Cancer Res 10:4806-12. 2004
    ....
  54. ncbi request reprint Stereotactic body radiotherapy for unresectable pancreatic cancer
    Stephanie T Chang
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Front Radiat Ther Oncol 40:386-94. 2007
    ..SBRT is an effective method of treating patients resulting in excellent local control. Current research is aimed at defining the optimal method of combining this treatment with other cancer therapies...
  55. ncbi request reprint Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae
    Yijun Chen
    Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford University Medical Center, Stanford, CA 94305, USA
    Mol Cancer Res 3:669-77. 2005
    ..We propose that the SLT2 MAPK pathway is an important cell survival signaling pathway during ER stress. This study shows the feasibility of using the yeast deletion pool to identify relevant mammalian orthologues of the UPR...

Research Grants4

  1. The Role of XBP1 During Hypoxia and Tumor Growth
    Albert Koong; Fiscal Year: 2005
    ..Ultimately, these studies may not only lead to the development of novel anticancer therapies based upon inhibition of XBP1 in tumors, but may also provide fundamental insights into our understanding of tumorigenesis. ..
  2. The Role of XBP1 During Hypoxia and Tumor Growth
    Albert Koong; Fiscal Year: 2006
    ..Ultimately, these studies may not only lead to the development of novel anticancer therapies based upon inhibition of XBP1 in tumors, but may also provide fundamental insights into our understanding of tumorigenesis. ..
  3. The Role of XBP1 During Hypoxia and Tumor Growth
    Albert Koong; Fiscal Year: 2007
    ..Ultimately, these studies may not only lead to the development of novel anticancer therapies based upon inhibition of XBP1 in tumors, but may also provide fundamental insights into our understanding of tumorigenesis. ..