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Genomes and Genes | Christina S KongSummaryAffiliation: Stanford University Country: USA Publications
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Publications
Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapseChristina S Kong
Department of Pathology, Stanford University, Stanford, California 94305 5324, USA
Oral Surg Oral Med Oral Pathol Oral Radiol 115:95-103. 2013..PERP is a p53/p63-regulated gene encoding a desmosomal protein that plays a critical role in cell-cell adhesion and tumor suppression...
A panel of 3 markers including p16, ProExC, or HPV ISH is optimal for distinguishing between primary endometrial and endocervical adenocarcinomasChristina S Kong
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
Am J Surg Pathol 34:915-26. 2010..However, these panels do not perform well with special variant carcinomas...
Role of human papillomavirus in squamous cell metaplasia-dysplasia-carcinoma of the rectumChristina S Kong
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
Am J Surg Pathol 31:919-25. 2007..Further studies are warranted to determine if SCC occurring more proximal in the colon are also HPV-dependent or occur via another, HPV-independent pathway...
p16INK4A immunohistochemistry is superior to HPV in situ hybridization for the detection of high-risk HPV in atypical squamous metaplasiaChristina S Kong
Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
Am J Surg Pathol 31:33-43. 2007....
The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomasChristina S Kong
Department of Pathology, Stanford University, Santa Cruz, CA, USA
Int J Radiat Oncol Biol Phys 74:553-61. 2009....
Evaluation of ProExC as a prognostic marker in oropharyngeal squamous cell carcinomasAnne M Mills
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Am J Surg Pathol 36:1158-64. 2012..These findings indicate that ProExC does not perform well enough to be used as a prognostic marker in oropharyngeal SCC. p16 should be used and scored as positive when at least half the tumor is strongly stained...
An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancersQuynh Thu Le
Department of Radiation Oncology, Stanford University Medical Center, Stanford, California 94305 5847, USA
Clin Cancer Res 12:1507-14. 2006..To directly assess tumor oxygenation in resectable non-small cell lung cancers (NSCLC) and to correlate tumor pO2 and the selected gene and protein expression to treatment outcomes...
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03Quynh Thu Le
Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
J Clin Oncol 27:4281-6. 2009..To validate lysyl oxidase (LOX), a hypoxia-related protein, as a marker for metastasis in an independent head and neck cancer (HNC) patient group enrolled onto a prospective trial...
p16 Is Superior to ProEx C in Identifying High-grade Squamous Intraepithelial Lesions (HSIL) of the Anal CanalRajeev Bala
Departments of Pathology Medicine, Division of Infectious Diseases and Geographic Medicine Department of Surgery, Stanford University School of Medicine, Stanford, CA
Am J Surg Pathol 37:659-68. 2013..These data suggest that strong and diffuse block-positive nuclear and cytoplasmic labeling with p16 is a highly specific biomarker for the presence of HR-HPV in anal biopsies and that this finding correlates with high-grade lesions...
Laboratory-developed L1 sequencing and type-specific, real-time polymerase chain reaction for the detection and typing of human papillomaviruses in formalin-fixed, paraffin-embedded tissuesAnne Mills
Department of Pathology, Division of Infectious Diseases, Stanford University School of Medicine, Palo Alto, California 94304, USA
Arch Pathol Lab Med 137:50-4. 2013....
Quantitation of human papillomavirus DNA in plasma of oropharyngeal carcinoma patientsHongbin Cao
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
Int J Radiat Oncol Biol Phys 82:e351-8. 2012..To determine whether human papillomavirus (HPV) DNA can be detected in the plasma of patients with HPV-positive oropharyngeal carcinoma (OPC) and to monitor its temporal change during radiotherapy...
Diagnostic problems in anal pathologyTeri A Longacre
Department of Pathology, Stanford University, Stanford, CA 94305, USA
Adv Anat Pathol 15:263-78. 2008..As all anal condylomata may harbor foci of high-grade dysplasia or invasive carcinoma, careful sectioning and complete histologic examination is required...
p16(INK4A) immunohistochemical staining may be helpful in distinguishing branchial cleft cysts from cystic squamous cell carcinomas originating in the oropharynxReetesh K Pai
Department of Pathology, Stanford University, Stanford, CA 94305, USA
Cancer 117:108-19. 2009..We investigated p16(INK4A) expression in branchial cleft cysts and its utility in distinguishing branchial cleft cysts from metastatic head and neck squamous cell carcinomas (SCCs) in fine-needle aspiration biopsies (FNABs)...
Are women with endocervical adenocarcinoma at risk for lynch syndrome? Evaluation of 101 cases including unusual subtypes and lower uterine segment tumorsAnne M Mills
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Gynecol Pathol 31:463-9. 2012..MMR testing is prudent in lower uterine segment tumors in women with possible LS, especially those for which definitive site of origin cannot be determined...
Cytologic evaluation of lymphadenopathy associated with mycosis fungoides and Sezary syndrome: role of immunophenotypic and molecular ancillary studiesReetesh K Pai
Department of Pathology, Stanford University, Stanford, California 94305, USA
Cancer 114:323-32. 2008..With fine-needle aspiration biopsy, material can be collected for ancillary diagnostic studies and for morphologic evaluation...
Cytology of desmoplastic small round-cell tumor: comparison of pre- and post-chemotherapy fine-needle aspiration biopsiesAlison E Presley
Department of Pathology, University of Virginia, Charlottesville, Virginia 22908 0214, USA
Cancer 111:41-6. 2007..This study was designed to compare prechemotherapy and postchemotherapy cytomorphology of DSRCT and to evaluate for distinct chemotherapy-induced changes...
Burkitt's lymphoma presenting as a rapidly growing thyroid massJudith E Kalinyak
Thyroid Clinic, Division of Nuclear Medicine, Stanford University School of Medicine, Stanford, California, USA
Thyroid 16:1053-7. 2006..His presentation highlights the urgency in diagnosis and provides an opportunity to review a rare type of primary thyroid lymphoma...
Nodular fasciitis: diagnosis by fine needle aspiration biopsyChristina S Kong
Department of Pathology, Stanford University, Stanford, California 94305-5324, USA
Acta Cytol 48:473-7. 2004..Cytologic diagnosis of nodular fasciitis is important since it obviates the need for surgical excision...
Endometrial adenocarcinoma associated with subtle lymph-vascular space invasion and lymph node metastasis: a histologic pattern mimicking intravascular and sinusoidal histiocytesJesse K McKenney
Department of Pathology, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Int J Gynecol Pathol 24:73-8. 2005..Two cases had regional lymph node metastases composed of morphologically similar cells...
BD focalpoint slide profiler performance with atypical glandular cells on SurePath Papanicolaou smearsDeborah J Chute
Department of Pathology, University of Virginia, Charlottesville, VA 22908, USA
Cancer Cytopathol 118:68-74. 2010..It identifies up to 25% of slides as requiring No Further Review. However, few studies have evaluated FocalPoint performance with glandular abnormalities...
Cytologic diagnosis of Burkitt lymphomaMegan L Troxell
Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA
Cancer 105:310-8. 2005..CONCLUSIONS: These cases illustrated the value of FNAB in the diagnosis of Burkitt lymphoma, as well as the importance of obtaining material for, and integrating results of, ancillary studies for the final diagnosis...
A novel aldehyde dehydrogenase-3 activator leads to adult salivary stem cell enrichment in vivoAlice Banh
Department of Radiation Oncology, Stanford University, California, 94305, USA
Clin Cancer Res 17:7265-72. 2011..To assess aldehyde dehydrogenase (ALDH) expression in adult human and murine submandibular gland (SMG) stem cells and to determine the effect of ALDH3 activation in SMG stem cell enrichment...
Cytologic diagnosis of columnar-cell lesions of the breastKristin C Jensen
Department of Pathology, Stanford University School of Medicine, Stanford, California 94305 5324, USA
Diagn Cytopathol 35:73-9. 2007..The prospective diagnosis of CCL cannot reliably be made by fine-needle aspiration. However, it is important to recognize the range of cytologic atypia that can be seen with CCL to avoid an overdiagnosis of malignancy...
Laryngeal embryonal rhabdomyosarcoma: a case of cervical metastases 13 years after treatment and a 25-year review of existing literatureRanjiv Sivanandan
Department of Otolaryngology Head and Neck Surgery, Stanford University Hospital, 300 Pasteur Drive, Edwards R 135, Stanford, CA 94305, USA
Arch Otolaryngol Head Neck Surg 130:1217-22. 2004..Embryonal rhabdomyosarcoma of the larynx is highly responsive to combination chemoradiotherapy, allowing for excellent cure rates without the need for extensive surgery. Late relapses warrant long-term follow-up...
Ectopic intrathyroidal thymoma: a case report and reviewJason B Cohen
Division of Nuclear Medicine, Stanford University School of Medicine, Stanford, California 94305-5281, USA
Thyroid 13:305-8. 2003..A diagnosis of ectopic intrathyroidal thymoma was made only after appropriate histopathologic assessment of the surgical specimen...
A novel technique for the enrichment of primary ovarian cancer cellsJohn K Chan
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, San Francisco, UCSF Comprehensive Cancer Center, 94143 1702, USA
Am J Obstet Gynecol 197:507.e1-5. 2007..We describe an efficient and effective method of enriching ovarian tumor cells from ascitic fluid using an immunomagnetic-based method...
