M Kondo

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines
    M Kondo
    Department of Pathology, Stanford University School of Medicine, California 94305 5324, USA
    Nature 407:383-6. 2000
  2. ncbi request reprint Lymphocyte development from hematopoietic stem cells
    M Kondo
    Department of Pathology, Stanford University School of Medicine, B259 Beckman Center, Stanford, CA 94305, USA
    Curr Opin Genet Dev 11:520-6. 2001
  3. ncbi request reprint Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice
    M Kondo
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Immunity 7:155-62. 1997
  4. pmc Two distinct pathways of positive selection for thymocytes
    K Akashi
    Departments of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 95:2486-91. 1998
  5. ncbi request reprint Role of interleukin-7 in T-cell development from hematopoietic stem cells
    K Akashi
    Department of Pathology, Standford University School of Medicine 94305, USA
    Immunol Rev 165:13-28. 1998
  6. ncbi request reprint Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    M Kondo
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Cell 91:661-72. 1997
  7. ncbi request reprint Lymphoid development from hematopoietic stem cells
    K Akashi
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Int J Hematol 69:217-26. 1999
  8. ncbi request reprint Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    K Akashi
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Cell 89:1033-41. 1997
  9. ncbi request reprint A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation
    M Kondo
    Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Cell Death Differ 11:1092-101. 2004
  10. pmc Leaky phenotype of X-linked agammaglobulinaemia in a Japanese family
    H Kaneko
    Department of Paediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan
    Clin Exp Immunol 140:520-3. 2005

Collaborators

  • K Akashi
  • J Domen
  • T Miyamoto
  • M G Manz
  • D Traver
  • Yoshiya Tanaka
  • A G King
  • H Kaneko
  • T Itoh
  • H Horikoshi
  • T Asano
  • E Matsui
  • T Teramoto
  • K Kasahara
  • N Kondo
  • T Fukao
  • N Kawamoto
  • Y Mabuchi
  • O Nishimura
  • M Fujino
  • K Igarashi
  • R Sasada
  • M Suenaga
  • M Kobayashi
  • N Koyama
  • K Sugamura
  • Y Kimura
  • S Watanabe
  • H Fujita
  • K Takatsu
  • N Ishii
  • M Nakamura
  • J Van Snick
  • K Arai
  • T Takeshita
  • K Furuyama
  • S Taketani
  • M Terajima
  • T Nagai
  • R A Galbraith
  • N Nomura
  • R Akagi
  • S Sassa

Detail Information

Publications16

  1. ncbi request reprint Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines
    M Kondo
    Department of Pathology, Stanford University School of Medicine, California 94305 5324, USA
    Nature 407:383-6. 2000
    ..We conclude that cytokine signalling can regulate cell-fate decisions and propose that a critical step in lymphoid commitment is downregulation of cytokine receptors that drive myeloid cell development...
  2. ncbi request reprint Lymphocyte development from hematopoietic stem cells
    M Kondo
    Department of Pathology, Stanford University School of Medicine, B259 Beckman Center, Stanford, CA 94305, USA
    Curr Opin Genet Dev 11:520-6. 2001
    ..Now that we can purify progenitors at different maturational stages during lymphocyte development, the challenge is to understand the processes that govern each developmental stage transition...
  3. ncbi request reprint Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice
    M Kondo
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Immunity 7:155-62. 1997
    ..Therefore, the development of T, B, and NK cells may be influenced by distinct intracytoplasmic signaling cascades that are activated by coupling of gamma(c)-related receptors...
  4. pmc Two distinct pathways of positive selection for thymocytes
    K Akashi
    Departments of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 95:2486-91. 1998
    ..In this view, positive selection on the c-Kit- path results from a salvage of cells that failed positive selection on the c-Kit+ path...
  5. ncbi request reprint Role of interleukin-7 in T-cell development from hematopoietic stem cells
    K Akashi
    Department of Pathology, Standford University School of Medicine 94305, USA
    Immunol Rev 165:13-28. 1998
    ..Detailed analysis of the signaling cascades activated by the IL-7R may help to reveal the differential roles of IL-7 signaling in T and B-cell development...
  6. ncbi request reprint Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    M Kondo
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Cell 91:661-72. 1997
    ..A single Lin(-)IL-7R(+)Thy-1(-)Sca-1loc-Kit(lo) cell could generate at least both T and B cells. These data provide direct evidence for the existence of common lymphoid progenitors in sites of early hematopoiesis...
  7. ncbi request reprint Lymphoid development from hematopoietic stem cells
    K Akashi
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Int J Hematol 69:217-26. 1999
    ..Thus, common lymphoid progenitors exist in early hematopoiesis, and expression of the IL-7R is a critical step in the initiation of lymphoid development from HSC...
  8. ncbi request reprint Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    K Akashi
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Cell 89:1033-41. 1997
    ..We propose cell survival signals to be the principal function of IL-7R engagement in thymic and T cell development...
  9. ncbi request reprint A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation
    M Kondo
    Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Cell Death Differ 11:1092-101. 2004
    ....
  10. pmc Leaky phenotype of X-linked agammaglobulinaemia in a Japanese family
    H Kaneko
    Department of Paediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan
    Clin Exp Immunol 140:520-3. 2005
    ..The increased frequency of infection with age expanded the number of B cells with normal BTK gene expression and produced the serum immunoglobulin, including IgE...
  11. ncbi request reprint Novel betacellulin derivatives. Separation of the differentiation activity from the mitogenic activity
    T Itoh
    Pharmaceutical Research Division, Takeda Chemical Industries, Ltd, Wadai 10, Tsukuba, Ibaraki 300 4293, Japan
    J Biol Chem 276:40698-703. 2001
    ..The derivatives described in the present study should be helpful in future applications as therapeutic proteins and in basic research for discovery of a BTC-specific receptor...
  12. ncbi request reprint Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex
    Y Kimura
    Department of Microbiology, Tohoku University School of Medicine, Sendai, Japan
    Int Immunol 7:115-20. 1995
    ..These results demonstrate that the gamma c chain is included in the functional receptor complex for IL-9, which was initially characterized as a T cell growth factor and is essential for IL-9-dependent growth signal transduction...
  13. ncbi request reprint Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4
    M Kondo
    Department of Microbiology, Tohoku University School of Medicine, Sendai, Japan
    Science 262:1874-7. 1993
    ..These results suggest that the IL-2 receptor gamma chain is functionally involved in the IL-4 receptor complex...
  14. ncbi request reprint Characterization and expression of cDNA encoding coproporphyrinogen oxidase from a patient with hereditary coproporphyria
    H Fujita
    Tohoku University School of Medicine, Sendai, Japan
    Hum Mol Genet 3:1807-10. 1994
    ....
  15. ncbi request reprint Involvement of the interleukin-2 receptor gamma subunit in interleukin-4-dependent activation of mouse hematopoietic cells and splenic B cells
    S Watanabe
    Department of Molecular and Developmental Biology, University of Tokyo, Japan
    Eur J Immunol 25:126-31. 1995
    ..The induction of major histocompatibility complex class II molecules or CD23 by IL-4 was virtually unaffected by TUGm2 antibody. These results indicate that IL-2R gamma is differentially involved in various IL-4-dependent reactions...
  16. ncbi request reprint Characterization of T-cell clones specific to ovomucoid from patients with egg-white allergy
    M Kondo
    Department of Pediatrics, Graduate School of Medicine, Gifu University Japan
    J Investig Allergol Clin Immunol 15:107-11. 2005
    ..We characterized their reactive epitopes, antigen-presenting molecules (HLA class II), and usage of TCR alpha and beta genes and the CDR3 loop sequence...