BRIAN D KNUTSON

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Interactivity and reward-related neural activation during a serious videogame
    Steven W Cole
    HopeLab Foundation, Redwood City, California, United States of America
    PLoS ONE 7:e33909. 2012
  2. pmc Gain and loss learning differentially contribute to life financial outcomes
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, California, United States of America
    PLoS ONE 6:e24390. 2011
  3. pmc Anticipatory affect: neural correlates and consequences for choice
    Brian Knutson
    Department of Psychology, Stanford University, Building 420, Jordan Hall, Stanford, CA 94305, USA
    Philos Trans R Soc Lond B Biol Sci 363:3771-86. 2008
  4. ncbi request reprint Neural antecedents of the endowment effect
    Brian Knutson
    Psychology and Neuroscience, Stanford University, Stanford, CA 94305, USA
    Neuron 58:814-22. 2008
  5. doi request reprint Nucleus accumbens activation mediates the influence of reward cues on financial risk taking
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Neuroreport 19:509-13. 2008
  6. pmc Neural responses to monetary incentives in major depression
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, California 94305, USA
    Biol Psychiatry 63:686-92. 2008
  7. ncbi request reprint Neural antecedents of financial decisions
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, California 94305, USA
    J Neurosci 27:8174-7. 2007
  8. ncbi request reprint Splitting the difference: how does the brain code reward episodes?
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Ann N Y Acad Sci 1104:54-69. 2007
  9. ncbi request reprint Linking nucleus accumbens dopamine and blood oxygenation
    Brian Knutson
    Department of Psychology, Stanford University, Building 420, Jordan Hall, Stanford, CA 94305, USA
    Psychopharmacology (Berl) 191:813-22. 2007
  10. ncbi request reprint Amphetamine modulates human incentive processing
    Brian Knutson
    Department of Psychology, Stanford University, CA 94305, USA
    Neuron 43:261-9. 2004

Research Grants

Detail Information

Publications33

  1. pmc Interactivity and reward-related neural activation during a serious videogame
    Steven W Cole
    HopeLab Foundation, Redwood City, California, United States of America
    PLoS ONE 7:e33909. 2012
    ....
  2. pmc Gain and loss learning differentially contribute to life financial outcomes
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, California, United States of America
    PLoS ONE 6:e24390. 2011
    ..These findings support the notion that different gain and loss learning systems may exert a cumulative influence on distinct life financial outcomes...
  3. pmc Anticipatory affect: neural correlates and consequences for choice
    Brian Knutson
    Department of Psychology, Stanford University, Building 420, Jordan Hall, Stanford, CA 94305, USA
    Philos Trans R Soc Lond B Biol Sci 363:3771-86. 2008
    ..Together, these findings support a neurally plausible framework for understanding how anticipatory affect can influence choice...
  4. ncbi request reprint Neural antecedents of the endowment effect
    Brian Knutson
    Psychology and Neuroscience, Stanford University, Stanford, CA 94305, USA
    Neuron 58:814-22. 2008
    ..These findings are consistent with a reference-dependent account in which ownership increases value by enhancing the salience of the possible loss of preferred products...
  5. doi request reprint Nucleus accumbens activation mediates the influence of reward cues on financial risk taking
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Neuroreport 19:509-13. 2008
    ....
  6. pmc Neural responses to monetary incentives in major depression
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, California 94305, USA
    Biol Psychiatry 63:686-92. 2008
    ..In the present study, we compared neural correlates of monetary incentive processing in unmedicated depressed participants and never-depressed control subjects...
  7. ncbi request reprint Neural antecedents of financial decisions
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, California 94305, USA
    J Neurosci 27:8174-7. 2007
    ..These findings have implications for predicting choices and for building a physiologically constrained theory of decision-making...
  8. ncbi request reprint Splitting the difference: how does the brain code reward episodes?
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Ann N Y Acad Sci 1104:54-69. 2007
    ..In addition to offering a more comprehensive and anatomically situated view of reward processing, split error terms generate novel predictions about psychiatric symptoms and lesion-induced deficits...
  9. ncbi request reprint Linking nucleus accumbens dopamine and blood oxygenation
    Brian Knutson
    Department of Psychology, Stanford University, Building 420, Jordan Hall, Stanford, CA 94305, USA
    Psychopharmacology (Berl) 191:813-22. 2007
    ..However, the physiological relationship between dopamine release and BOLD signal increases in the NAcc has not yet been established...
  10. ncbi request reprint Amphetamine modulates human incentive processing
    Brian Knutson
    Department of Psychology, Stanford University, CA 94305, USA
    Neuron 43:261-9. 2004
    ..These findings suggest that therapeutic effects of amphetamine on incentive processing may involve reducing the difference between anticipation of gains and losses...
  11. ncbi request reprint Behavior. Sweet revenge?
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Science 305:1246-7. 2004
  12. ncbi request reprint Distributed neural representation of expected value
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, California 94305, USA
    J Neurosci 25:4806-12. 2005
    ....
  13. ncbi request reprint Functional magnetic resonance imaging of reward prediction
    Brian Knutson
    Psychology Department, Stanford University, Stanford, California 94305, USA
    Curr Opin Neurol 18:411-7. 2005
    ....
  14. ncbi request reprint A region of mesial prefrontal cortex tracks monetarily rewarding outcomes: characterization with rapid event-related fMRI
    Brian Knutson
    Department of Psychology, Building 420, Jordan Hall, Stanford University, Stanford, CA 94305 2130, USA
    Neuroimage 18:263-72. 2003
    ..00 win, MPFC activity decreased, relative to outcomes with no incentive value. These findings suggest that in the context of processing monetary rewards, a region of the MPFC preferentially tracks rewarding outcomes...
  15. ncbi request reprint Ultrasonic vocalizations as indices of affective states in rats
    Brian Knutson
    Department of Psychology, Stanford University, California 94305, USA
    Psychol Bull 128:961-77. 2002
    ..This hypothesis has theoretical implications for understanding the brain circuitry underlying mammalian affective states and clinical applicability for modeling hedonic properties of different psychotropic compounds...
  16. pmc Neural predictors of purchases
    Brian Knutson
    Psychology and Neuroscience, Stanford University, Building 420, Jordan Hall, Stanford, CA 94305, USA
    Neuron 53:147-56. 2007
    ..These findings suggest that activation of distinct neural circuits related to anticipatory affect precedes and supports consumers' purchasing decisions...
  17. ncbi request reprint Ventral striatal hyporesponsiveness during reward anticipation in attention-deficit/hyperactivity disorder
    Anouk Scheres
    Department of Psychology, University of Arizona, Tucson, Arizona 85721, USA
    Biol Psychiatry 61:720-4. 2007
    ..Although abnormalities in reward processing have been proposed to underlie attention-deficit/hyperactivity disorder (ADHD), this link has not been tested explicitly with neural probes...
  18. ncbi request reprint Remembrance of rewards past
    Brian Knutson
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Neuron 45:331-2. 2005
    ..We propose that their findings introduce a novel mechanism by which positive arousal induced by reward anticipation may promote memory...
  19. pmc Available alternative incentives modulate anticipatory nucleus accumbens activation
    Jeffrey C Cooper
    Department of Psychology, Stanford University, Jordan Hall, 450 Serra Mall, Stanford, CA 94305, USA
    Soc Cogn Affect Neurosci 4:409-16. 2009
    ..These findings imply that NAcc activation represents anticipated incentive value relative to the current context of available alternative gains and losses...
  20. pmc Variability in nucleus accumbens activity mediates age-related suboptimal financial risk taking
    Gregory R Samanez-Larkin
    Department of Psychology, Stanford University, Stanford, California 94305 2130, USA
    J Neurosci 30:1426-34. 2010
    ..This age-related effect was mediated by a neural measure of temporal variability in nucleus accumbens activity. These findings reveal a novel neural mechanism by which aging may disrupt rational financial choice...
  21. pmc Dissociable neural representations of future reward magnitude and delay during temporal discounting
    Kacey Ballard
    Department of Psychology, Stanford University, CA 94305, USA
    Neuroimage 45:143-50. 2009
    ....
  22. pmc Saving for the future self: neural measures of future self-continuity predict temporal discounting
    Hal Ersner-Hershfield
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Soc Cogn Affect Neurosci 4:85-92. 2009
    ..In addition to supporting the future self-continuity hypothesis, these findings hold implications for significant financial decisions, such as choosing whether to save for the future or spend in the present...
  23. pmc Expected value information improves financial risk taking across the adult life span
    Gregory R Samanez-Larkin
    Jordan Hall, Building 420, 450 Serra Mall, Stanford, CA 94305 2130, USA
    Soc Cogn Affect Neurosci 6:207-17. 2011
    ....
  24. ncbi request reprint Cultural variation in affect valuation
    Jeanne L Tsai
    Department of Psychology, Stanford University, CA 94305, USA
    J Pers Soc Psychol 90:288-307. 2006
    ..These findings illustrate the distinctiveness of ideal and actual affect, show that culture influences ideal affect more than actual affect, and indicate that both play a role in mental health...
  25. ncbi request reprint The neural basis of financial risk taking
    Camelia M Kuhnen
    Stanford Graduate School of Business, 518 Memorial Way, S479, Stanford, California, 94305, USA
    Neuron 47:763-70. 2005
    ..Thus, consideration of anticipatory neural mechanisms may add predictive power to the rational actor model of economic decision making...
  26. pmc Anticipation of monetary gain but not loss in healthy older adults
    Gregory R Samanez-Larkin
    Department of Psychology, Stanford University, Jordan Hall, Building 420, Stanford, California 94305 2130, USA
    Nat Neurosci 10:787-91. 2007
    ..These findings suggest that there is an asymmetry in the processing of gains and losses in older adults that may have implications for decision-making...
  27. pmc Valence and salience contribute to nucleus accumbens activation
    Jeffrey C Cooper
    Department of Psychology, Jordan Hall, 450 Serra Mall, Stanford, CA 94305, USA
    Neuroimage 39:538-47. 2008
    ..These findings suggest that NAcc activation separately represents both valence and salience, consistent with its hypothesized role in appetitive motivation...
  28. pmc Individual differences in insular sensitivity during loss anticipation predict avoidance learning
    Gregory R Samanez-Larkin
    Department of Psychology, Stanford University, Stanford, CA 94305 2130, USA
    Psychol Sci 19:320-3. 2008
    ..These findings suggest that in addition to correlating with self-reported anxiety, heightened insular sensitivity may promote learning to avoid loss...
  29. pmc The affective impact of financial skewness on neural activity and choice
    Charlene C Wu
    Psychology and Neuroscience, Stanford University, Stanford, California, United States of America
    PLoS ONE 6:e16838. 2011
    ..These findings support an anticipatory affect account in which statistical properties of gambles--including skewness--can influence neural activity, affective responses, and ultimately, choice...
  30. pmc When giving is good: ventromedial prefrontal cortex activation for others' intentions
    Jeffrey C Cooper
    Department of Psychology, Stanford University, Stanford, CA 94305, USA
    Neuron 67:511-21. 2010
    ..These results demonstrate that neural responses to others' generosity or selfishness depend not only on their actions but also on their perceived intentions...
  31. doi request reprint Interpretable classifiers for FMRI improve prediction of purchases
    Logan Grosenick
    Neuroscience Institute at Stanford, Stanford University, Stanford, CA 94305 USA
    IEEE Trans Neural Syst Rehabil Eng 16:539-48. 2008
    ..More broadly, this approach provides a general framework for using neuroimaging data to build interpretable models, including those that predict choice...
  32. ncbi request reprint The lure of the unknown
    Brian Knutson
    Department of Psychology, Stanford University
    Neuron 51:280-2. 2006
    ..These findings indicate that midbrain regions preferentially respond to novelty and suggest that novelty can serve as its own reward...
  33. ncbi request reprint The role of brain emotional systems in addictions: a neuro-evolutionary perspective and new 'self-report' animal model
    Jaak Panksepp
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior Bowling Green State University, OH 43403, USA
    Addiction 97:459-69. 2002
    ..We conclude by discussing some therapeutic and social implications of examining drug addiction processes with multiple emotional brain systems in mind...

Research Grants4

  1. Anticipation of Reward and Risk Across the Lifespan
    Brian Knutson; Fiscal Year: 2007
    ..The findings promise to illuminate how individuals make both optimal and suboptimal financial decisions over the course of the lifespan. ..
  2. A neurobehavioral probe of human reward function
    Brian Knutson; Fiscal Year: 2002
    ..g., anhedonic unipolar depression), the likelihood of recovery, and efficacy of pharmacotherapeutic or psychotherapeutic interventions. ..
  3. Neuroscience probes of cigarette craving & consumption
    Brian Knutson; Fiscal Year: 2005
    ..Methods developed in this application may also provide a useful index of addiction and individual proclivity towards relapse. ..