Research Topics
| ERIC KNUDSENSummaryAffiliation: Stanford University Country: USA Publications
Research Grants
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Detail Information
Publications
Top-down gain control of the auditory space map by gaze control circuitry in the barn owlDaniel E Winkowski
Department of Neurobiology, Stanford University, Stanford, California 94305, USA
Nature 439:336-9. 2006..This approach provides a path for discovering mechanisms that underlie top-down gain control in the central nervous system...
Fundamental components of attentionEric I Knudsen
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305 5125, USA
Annu Rev Neurosci 30:57-78. 2007..Recent results from neurobiological research on attention are discussed within this framework...
Control from below: the role of a midbrain network in spatial attentionEric I Knudsen
Department of Neurobiology, 299 Campus Dr, Stanford University School of Medicine, Stanford, CA 94305 5125, USA
Eur J Neurosci 33:1961-72. 2011..The following review discusses the role of the midbrain network in controlling attention, the neural circuits that support this role and current knowledge about the computations performed by these circuits...
Economic, neurobiological, and behavioral perspectives on building America's future workforceEric I Knudsen
Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305 5125, USA
Proc Natl Acad Sci U S A 103:10155-62. 2006....
Sensitive periods in the development of the brain and behaviorEric I Knudsen
Department of Neurobiology, Stanford University School of Medicine, Sherman Fairchild Sciences Building, Stanfrord, CA 94305 5125, USA
J Cogn Neurosci 16:1412-25. 2004....
Instructed learning in the auditory localization pathway of the barn owlEric I Knudsen
Department of Neurobiology, Stanford University School of Medicine, CA 94305, USA
Nature 417:322-8. 2002..This example of instructed plasticity is highly quantifiable and demonstrates mechanisms and principles of learning that may be used widely throughout the central nervous system...
Adaptive plasticity in the auditory thalamus of juvenile barn owlsGreg L Miller
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305-5125, USA
J Neurosci 23:1059-65. 2003....
Incremental training increases the plasticity of the auditory space map in adult barn owlsBrie A Linkenhoker
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305-5125, USA
Nature 419:293-6. 2002....
The optic tectum controls visually guided adaptive plasticity in the owl's auditory space mapPeter S Hyde
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305, USA
Nature 415:73-6. 2002..Because the site of adaptive changes is the ICX, the results also indicate that the tectum provides a topographic instructive signal that controls adaptive auditory plasticity in the ICX...
Adaptation in the auditory space map of the barn owlYoram Gutfreund
Department of Neurobiology, Stanford University, Stanford, California, USA
J Neurophysiol 96:813-25. 2006....
Dynamic shifts in the owl's auditory space map predict moving sound locationIlana B Witten
Department of Neurobiology, Stanford University Medical School, Stanford, California 94305, USA
Nat Neurosci 9:1439-45. 2006..This hypothesis is consistent with perceptions of stimulus motion in humans for many sensory parameters...
Anatomical traces of juvenile learning in the auditory system of adult barn owlsBrie Ann Linkenhoker
Department of Neurobiology, Fairchild Science Building, Stanford University School of Medicine, Stanford, California 94305, USA
Nat Neurosci 8:93-8. 2005..This maintenance of silenced neural circuitry that was once adaptive may represent an important mechanism by which the brain preserves a record of early experience...
Hunting increases adaptive auditory map plasticity in adult barn owlsJoseph F Bergan
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305-5125, USA
J Neurosci 25:9816-20. 2005..These results indicate that the experience of hunting dramatically increases adult adaptive plasticity in this pathway...
Distinct mechanisms for top-down control of neural gain and sensitivity in the owl optic tectumDaniel E Winkowski
Neurobiology Department, Stanford University Medical Center, 299 Campus Drive West, Stanford, CA 94305 5125, USA
Neuron 60:698-708. 2008..The coordinated action of these different mechanisms can account for many of the reported effects of spatial attention on neural responses in monkeys and on behavioral performance in humans...
Multiple sites of adaptive plasticity in the owl's auditory localization pathwayWilliam M DeBello
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305-5125, USA
J Neurosci 24:6853-61. 2004..Because plasticity at both sites has been shown to decline substantially in adults, these results suggest that an age-dependent decrease in auditory map plasticity occurs first in the ICX and later at the higher level, in the OT...
Visual modulation of auditory responses in the owl inferior colliculusJoseph F Bergan
Department of Neurobiology, Stanford University, Stanford, California 94305, USA
J Neurophysiol 101:2924-33. 2009....
Why seeing is believing: merging auditory and visual worldsIlana B Witten
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305, USA
Neuron 48:489-96. 2005..We consider candidate neural codes that would enable optimal integration and the implications of optimal integration for perception and plasticity...
Global inhibition and stimulus competition in the owl optic tectumShreesh P Mysore
Department of Neurobiology, Stanford University, Stanford, California 94305, USA
J Neurosci 30:1727-38. 2010..We hypothesize that this global, cross-modal inhibition, which acts automatically in a bottom-up manner even in sedated animals, is critical to the creation of a map of stimulus salience in the optic tectum...
Stimulus-driven competition in a cholinergic midbrain nucleusAli Asadollahi
Department of Neurobiology, Stanford School of Medicine, Stanford, California, USA
Nat Neurosci 13:889-95. 2010..The functional properties of Ipc neurons resembled those of a salience map, a core component in computational models for spatial attention and gaze control...
A Hebbian learning rule mediates asymmetric plasticity in aligning sensory representationsIlana B Witten
Neurobiology Department, Stanford University Medical Center, Stanford, CA 94305, USA
J Neurophysiol 100:1067-79. 2008..These same principles would apply not only to the maintenance of spatial registry across input channels, but also to the experience-dependent emergence of aligned representations in developing circuits...
Top-down control of multimodal sensitivity in the barn owl optic tectumDaniel E Winkowski
Stanford University Medical Center, Neurobiology Department, Stanford, California 94305 5125, USA
J Neurosci 27:13279-91. 2007..This experimental approach provides a means for discovering mechanisms that underlie the top-down regulation of sensory responses...
Intrinsic excitability of cholinergic neurons in the rat parabigeminal nucleusC Alex Goddard
Department of Neurobiology, Stanford University, Stanford, CA, 94305, USA
J Neurophysiol 98:3486-93. 2007..Ultimately, the spontaneous activity in PBN neurons could be used to modulate cholinergic drive in the superior colliculus in either positive or negative directions...
Adaptive auditory plasticity in developing and adult animalsAlex S Keuroghlian
Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305 5125, United States
Prog Neurobiol 82:109-21. 2007....
Gated visual input to the central auditory systemYoram Gutfreund
Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA
Science 297:1556-9. 2002..Thus, visual spatial information is gated into the auditory system by an inhibitory mechanism that operates at a higher level in the brain...
Auditory and visual space maps in the cholinergic nucleus isthmi pars parvocellularis of the barn owlKristin A Maczko
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305 5125, USA
J Neurosci 26:12799-806. 2006..These findings, combined with the precise pattern of projections from the Ipc to the OT, suggest that the role of the Ipc is to regulate the sensitivity of OT neurons in a space-specific manner...
Auditory-visual fusion in speech perception in children with cochlear implantsEfrat A Schorr
Department of Human Development/Institute of Child Study, University of Maryland, 3304 Benjamin Building, College Park, MD 20742, USA
Proc Natl Acad Sci U S A 102:18748-50. 2005..The likelihood of consistent auditory-visual fusion declined with age at implant beyond 2.5 years, suggesting a sensitive period for bimodal integration in speech perception...
Research Grants
- Mechanisms of Instructed Learning in the Auditory SystemERIC KNUDSEN; Fiscal Year: 2006..abstract_text> ..
- ANALYSIS OF SPACE BY THE AUDITORY SYSTEMERIC KNUDSEN; Fiscal Year: 2007..abstract_text> ..
- ANALYSIS OF SPACE BY THE AUDITORY SYSTEMERIC KNUDSEN; Fiscal Year: 2002..In addition, the results should teach us much about the normal structure, function and development of the central auditory system. ..
- ANALYSIS OF SPACE BY THE AUDITORY SYSTEMERIC KNUDSEN; Fiscal Year: 1990....
- ANALYSIS OF SPACE BY THE AUDITORY SYSTEMERIC KNUDSEN; Fiscal Year: 1993....
- Neural Mechanisms of Visual and Auditory Stimulus SelectionERIC KNUDSEN; Fiscal Year: 2010..The results from this research will provide crucial information that may help in the development of treatments that can mitigate or remediate the devastating effects of these psychiatric conditions. ..
