Research Topics
| Christopher R KingSummaryAffiliation: Stanford University Country: USA Publications
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Publications
Postoperative prostate-specific antigen velocity independently predicts for failure of salvage radiotherapy after prostatectomyChristopher R King
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 70:1472-7. 2008..Identification of patients most likely to benefit from salvage radiotherapy (RT) using postoperative (postop) prostate-specific antigen (PSA) kinetics...
Obesity and risk of biochemical failure for patients receiving salvage radiotherapy after prostatectomyChristopher R King
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
Int J Radiat Oncol Biol Phys 73:1017-22. 2009..Using body mass index (BMI) as a measure of obesity, we tested its role as a risk factor for patients receiving salvage RT after prostatectomy...
Improved outcomes with higher doses for salvage radiotherapy after prostatectomyChristopher R King
Department of Radiation Oncology, Division of Urologic Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 71:23-7. 2008..To evaluate relapse-free survival with higher doses for patients receiving salvage radiotherapy (RT) after radical prostatectomy (RP)...
Prognostic significance of prostate cancer originating from the transition zoneChristopher R King
Department of Radiation Oncology, Division of Urologic Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Urol Oncol 27:592-7. 2009..To understand the influence of tumor location, we compared bRFS for TZ and PZ cancers stratified for risk using known clinical and pathological prognostic factors...
Impact of obesity on the utility of preoperative prostate-specific antigen velocity to predict for relapse after prostatectomy: a report from the SEARCH databaseChristopher R King
Division of Urologic Oncology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
Urology 69:921-6. 2007....
Stereotactic body radiotherapy for localized prostate cancer: interim results of a prospective phase II clinical trialChristopher R King
Department of Radiation Oncology, Division of Urologic Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 73:1043-8. 2009..The radiobiology of prostate cancer favors a hypofractionated dose regimen. We report results of a prospective Phase II clinical trial of stereotactic body radiotherapy (SBRT) for localized prostate cancer...
Optimal timing, cutoff, and method of calculation of preoperative prostate-specific antigen velocity to predict relapse after prostatectomy: a report from SEARCHChristopher R King
Department of Radiation Oncology, Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
Urology 69:732-7. 2007..We studied the timing, cutoff levels, and method of calculation to better define its usefulness...
Incidental testicular irradiation from prostate IMRT: it all adds upChristopher R King
Department of Radiation Oncology, Stanford University School of Medicine, Stanford Cancer Center, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 77:484-9. 2010..To identify the technical aspects of image-guided intensity-modulated radiation therapy (IMRT) for localized prostate cancer that could result in a clinically meaningful incidental dose to the testes...
Preoperative PSA velocity is an independent prognostic factor for relapse after radical prostatectomyDeep A Patel
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305-5847, USA
J Clin Oncol 23:6157-62. 2005..Its inclusion will be useful in risk stratification, evaluation for alternatives to surgery, and patient selection for neoadjuvant or adjuvant therapies as part of randomized clinical trials...
A study of image-guided intensity-modulated radiotherapy with fiducials for localized prostate cancer including pelvic lymph nodesAnnie Hsu
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
Int J Radiat Oncol Biol Phys 68:898-902. 2007..To study the impact on nodal coverage and dose to fixed organs at risk when using daily fiducial localization of the prostate to deliver intensity-modulated radiotherapy (IMRT)...
Radiotherapy after prostatectomy: improved biochemical relapse-free survival with whole pelvic compared with prostate bed only for high-risk patientsMichael T Spiotto
Department of Radiation Oncology, Division of Urologic Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 69:54-61. 2007..To compare the biochemical relapse-free survival (bRFS) among patients receiving whole pelvic radiotherapy (WPRT) vs. prostate bed RT (PBRT) after radical prostatectomy...
Investigation of linac-based image-guided hypofractionated prostate radiotherapyTodd Pawlicki
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
Med Dosim 32:71-9. 2007..During this study, we have also uncovered opportunities for improvement of the on-board imaging hardware/software implementation that would further enhance performance in this regard...
Radiotherapy after prostatectomy: is the evidence for dose escalation out there?Christopher R King
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 71:346-50. 2008..To study the effective doses of radiotherapy (RT) after prostatectomy in search for evidence of a dose-response...
Does hormone therapy exacerbate the adverse effects of radiotherapy in men with prostate cancer? A quality of life studyJonathan D Grant
Department of Radiation Oncology, University of California Los Angeles School of Medicine, Los Angeles, California 90095, USA
J Urol 185:1674-80. 2011....
Extended prostate biopsy scheme improves reliability of Gleason grading: implications for radiotherapy patientsChristopher R King
Division of Urologic Oncology, Department of Radiation, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 59:386-91. 2004..This study examines the concordance patterns between biopsy and matched radical prostatectomy Gleason grade among patients undergoing an extended 10-core biopsy scheme to assess its reliability compared to sextant biopsies...
Intraoperative radiation therapy for locally advanced and recurrent soft-tissue sarcomas in adultsPhuoc T Tran
Department of Radiation Oncology, Stanford Cancer Center, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 72:1146-53. 2008..To analyze the outcomes of and identify prognostic factors for patients treated with surgery and intraoperative radiotherapy (IORT) for locally advanced and recurrent soft-tissue sarcoma in adults from a single institution...
Reliability of small amounts of cancer in prostate biopsies to reveal pathologic gradeChristopher R King
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
Urology 67:1229-34. 2006..Prostate biopsy findings are known to undergrade prostate cancer compared with the pathologic specimens yet remain the only grade guiding disease management...
Radiotherapy after radical prostatectomy: does transient androgen suppression improve outcomes?Christopher R King
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 59:341-7. 2004....
Prostate biopsy volume indices do not predict for significant Gleason upgradingChristopher R King
Division of Urologic Oncology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA
Am J Clin Oncol 28:125-9. 2005..This suggests that the correlation that exists between such volume surrogates and outcomes after surgery reflect tumor volume effects only, independently of any possible association between tumor volume and Gleason grade...
Intrafractional motion of the prostate during hypofractionated radiotherapyYaoqin Xie
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
Int J Radiat Oncol Biol Phys 72:236-46. 2008..To report the characteristics of prostate motion as tracked by the stereoscopic X-ray images of the implanted fiducials during hypofractionated radiotherapy with CyberKnife...
A new formula for normal tissue complication probability (NTCP) as a function of equivalent uniform dose (EUD)Gary Luxton
Department of Radiation Oncology, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA 94305, USA
Phys Med Biol 53:23-36. 2008..The inverse equation expresses EUD as a function of NTCP and is used to generate a table of EUD versus normal tissue complication probability for the Emami-Burman parameter fits as well as for OAR parameter sets from more recent data...
The timing of salvage radiotherapy after radical prostatectomy: a systematic reviewChristopher R King
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
Int J Radiat Oncol Biol Phys 84:104-11. 2012..Defining the optimal patient and treatment factors is essential and is particularly relevant within the context of adjuvant vs early vs delayed postoperative radiotherapy (RT)...
Sexual function after stereotactic body radiotherapy for prostate cancer: results of a prospective clinical trialEllen A Wiegner
Department of Radiation Oncology, Stanford University School of Medicine, CA, USA
Int J Radiat Oncol Biol Phys 78:442-8. 2010..To study the sexual quality of life for prostate cancer patients after stereotactic body radiotherapy (SBRT)...
LDR vs. HDR brachytherapy for localized prostate cancer: the view from radiobiological modelsChristopher R King
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Brachytherapy 1:219-26. 2002....
CyberKnife radiotherapy for localized prostate cancer: rationale and technical feasibilityChristopher R King
Department of Radiation Oncology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
Technol Cancer Res Treat 2:25-30. 2003..These capabilities are essential if one contemplates hypo-fractionated regimens with large dose-per-fraction sizes (>5Gy to 10Gy) and dose-escalation...
Yes, the alpha/beta ratio for prostate cancer is low or "methinks the lady doth protest too much...about a low alpha/beta that is"Christopher R King
Int J Radiat Oncol Biol Phys 54:626-7; author reply 627-8. 2002
