Research Topics
| Charles C KimSummaryAffiliation: Stanford University Country: USA Publications
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Publications
Improved analytical methods for microarray-based genome-composition analysisCharles C Kim
Department of Microbiology and Immunology, 299 Campus Drive, Stanford University Medical Center, Stanford, CA 94305, USA
Genome Biol 3:RESEARCH0065. 2002..Current methodology uses empirical determination of cutoffs for classification into these categories, but this methodology is subject to several problems that can result in the misclassification of many genes...- Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouseTrevor D Lawley
Department of Microbiology and Immunology, Stanford University, Stanford, California, USA
PLoS Pathog 2:e11. 2006.... - Significance analysis of lexical bias in microarray dataCharles C Kim
Microbiology and Immunology, Stanford University Medical Center, Stanford, CA, 94305, USA
BMC Bioinformatics 4:12. 2003..A number of sophisticated methods for identification of significant lexical trends are currently available, but these methods are generally too cumbersome for practical use by most microarray users... - Modulation of virulence by two acidified nitrite-responsive loci of Salmonella enterica serovar TyphimuriumCharles C Kim
Microbiology and Immunology, Stanford University Medical Center, California 94305, USA
Infect Immun 71:3196-205. 2003..We conclude that these genes are regulated by physiological nitrogen oxides and that the absence of these bacterial genes in some way diminishes the ability of mice to clear a low dose infection... - Delineation of upstream signaling events in the salmonella pathogenicity island 2 transcriptional activation pathwayCharles C Kim
Microbiology and Immunology, 299 Campus Drive, Stanford University Medical Center, Stanford, CA 94305, USA
J Bacteriol 186:4694-704. 2004..Additionally, EnvZ, but not acetyl phosphate, is required for maximal expression of SPI2 in the intracellular environment, suggesting that the in vitro SPI2 activation pathway is the same as that used in vivo... - Identification of MglA-regulated genes reveals novel virulence factors in Francisella tularensisAnna Brotcke
Department of Microbiology and Immunology, Stanford University School of Medicine, 299 Campus Drive, Fairchild Bldg D041, Stanford, CA 94305, USA
Infect Immun 74:6642-55. 2006..We have identified five new Francisella virulence genes, and our results suggest that characterizations of additional MglA-regulated genes will yield further insights into the pathogenesis of this bacterium... - Microarray-based detection of Salmonella enterica serovar Typhimurium transposon mutants that cannot survive in macrophages and miceKaman Chan
Department of Microbiology and Immunology, Stanford University School of Medicine, 299 Campus Drive, Stanford, CA 94305 5124, USA
Infect Immun 73:5438-49. 2005..enterica serovar Typhimurium STM screen, illustrating the utility of this approach for the high-throughput identification of virulence factors important for survival in the host... - Genomic comparison of Salmonella enterica serovars and Salmonella bongori by use of an S. enterica serovar typhimurium DNA microarrayKaman Chan
Department of Microbiology and Immunology, Stanford University School of Medicine, California 94305 5124, USA
J Bacteriol 185:553-63. 2003.... - LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genesElizabeth A Joyce
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
Infect Immun 72:2964-75. 2004..Our analysis of an S. pneumoniae transcriptome revealed a function for LuxS in gene regulation that is not dependent upon high cell density and is likely involved in the maintenance of pneumococcal load in susceptible hosts... - Growth phase-dependent response of Helicobacter pylori to iron starvationD Scott Merrell
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
Infect Immun 71:6510-25. 2003..Finally, bioinformatic analysis of the predicted promoter regions of the differentially regulated genes led to identification of several putative Fur boxes, suggesting a direct role for Fur in iron-dependent regulation of these genes... - Delineation of diverse macrophage activation programs in response to intracellular parasites and cytokinesShuyi Zhang
Department of Pathology, University of California San Francisco, CA, USA
PLoS Negl Trop Dis 4:e648. 2010.... - Experimental malaria infection triggers early expansion of natural killer cellsCharles C Kim
Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA
Infect Immun 76:5873-82. 2008..These data indicate that the early response to P. chabaudi infection of the blood is marked by a primary wave of interferon with a subsequent response by NK cells... - Protective immunity against Helicobacter is characterized by a unique transcriptional signatureAnne Mueller
Department of Microbiology and Immunology, Stanford University School of Medicine, Sherman Fairchild Science Building D 033, 299 Campus Drive, Stanford, CA 94305 5402, USA
Proc Natl Acad Sci U S A 100:12289-94. 2003..We propose a mechanism of protection that involves the effector responses of either or both lymphocyte subclasses as well as the previously unappreciated paracrine functions of adipose tissue surrounding the resident lymphocytes...