Purvesh Khatri

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Ten years of pathway analysis: current approaches and outstanding challenges
    Purvesh Khatri
    Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS Comput Biol 8:e1002375. 2012
  2. pmc Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes
    Maarten Naesens
    Division of Nephrology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
    Kidney Int 80:1364-76. 2011
  3. doi request reprint Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury
    Tara K Sigdel
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    J Am Soc Nephrol 23:750-63. 2012
  4. pmc Comparison of multiplex meta analysis techniques for understanding the acute rejection of solid organ transplants
    Alexander A Morgan
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    BMC Bioinformatics 11:S6. 2010
  5. pmc SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
    Pawel K Mazur
    1 Department of Pediatrics, Stanford University School of Medicine, California 94305, USA 2 Department of Genetics, Stanford University School of Medicine, California 94305, USA 3
    Nature 510:283-7. 2014
  6. pmc A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma
    Ron Chen
    Authors Affiliations Cancer Biology Program, Division of Hematology Oncology, Department of Pediatrics Center for Biomedical Informatics Research, Department of Medicine Institute for Immunity, Transplant and Infection Department of Cardiothoracic Surgery and Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California
    Cancer Res 74:2892-902. 2014
  7. pmc Cell type-specific gene expression differences in complex tissues
    Shai S Shen-Orr
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
    Nat Methods 7:287-9. 2010
  8. pmc Profiling of autoantibodies in IgA nephropathy, an integrative antibiomics approach
    Tara K Sigdel
    Departments of Pediatrics Nephrology, Stanford University School of Medicine, Stanford, CA 94304, USA
    Clin J Am Soc Nephrol 6:2775-84. 2011

Collaborators

Detail Information

Publications8

  1. pmc Ten years of pathway analysis: current approaches and outstanding challenges
    Purvesh Khatri
    Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS Comput Biol 8:e1002375. 2012
    ....
  2. pmc Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes
    Maarten Naesens
    Division of Nephrology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
    Kidney Int 80:1364-76. 2011
    ..Thus, measurement of specific immune gene expression in protocol biopsies may be warranted to predict the development of subsequent chronic injury in histologically quiescent grafts and as a means to titrate immunosuppressive therapy...
  3. doi request reprint Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury
    Tara K Sigdel
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    J Am Soc Nephrol 23:750-63. 2012
    ..Validation in a larger, prospective transplant cohort may lead to a noninvasive method to predict and monitor for CAI...
  4. pmc Comparison of multiplex meta analysis techniques for understanding the acute rejection of solid organ transplants
    Alexander A Morgan
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    BMC Bioinformatics 11:S6. 2010
    ....
  5. pmc SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
    Pawel K Mazur
    1 Department of Pediatrics, Stanford University School of Medicine, California 94305, USA 2 Department of Genetics, Stanford University School of Medicine, California 94305, USA 3
    Nature 510:283-7. 2014
    ..Together, our results elucidate a new role for lysine methylation in integrating cytoplasmic kinase-signalling cascades and establish a pivotal role for SMYD3 in the regulation of oncogenic Ras signalling. ..
  6. pmc A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma
    Ron Chen
    Authors Affiliations Cancer Biology Program, Division of Hematology Oncology, Department of Pediatrics Center for Biomedical Informatics Research, Department of Medicine Institute for Immunity, Transplant and Infection Department of Cardiothoracic Surgery and Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California
    Cancer Res 74:2892-902. 2014
    ..Our work defines PTK7 as a highly and specifically expressed gene in adenocarcinoma and a potential therapeutic target in this subset of NSCLC...
  7. pmc Cell type-specific gene expression differences in complex tissues
    Shai S Shen-Orr
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
    Nat Methods 7:287-9. 2010
    ....
  8. pmc Profiling of autoantibodies in IgA nephropathy, an integrative antibiomics approach
    Tara K Sigdel
    Departments of Pediatrics Nephrology, Stanford University School of Medicine, Stanford, CA 94304, USA
    Clin J Am Soc Nephrol 6:2775-84. 2011
    ..Autoantibody (autoAb) biomarkers to detect and track progression of IgAN are an unmet clinical need. The objective of the study was to identify IgA-specific autoAbs specific to IgAN...