Terence A Ketter

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Predictors of treatment response in bipolar disorders: evidence from clinical and brain imaging studies
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Bipolar Disorders Clinic, Stanford University School of Medicine, CA 94305 5273, USA
    J Clin Psychiatry 63:21-5. 2002
  2. ncbi request reprint Stabilization of mood from below versus above baseline in bipolar disorder: a new nomenclature
    Terence A Ketter
    Department of Psychiatry and Behavioral Science, Stanford University School of Medicine, Calif 94305 5723, USA
    J Clin Psychiatry 63:146-51. 2002
  3. doi request reprint Long-term effectiveness of quetiapine in bipolar disorder in a clinical setting
    Terence A Ketter
    Stanford University School of Medicine, Stanford, CA 94305 5723, USA
    J Psychiatr Res 44:921-9. 2010
  4. doi request reprint Effectiveness of lamotrigine in bipolar disorder in a clinical setting
    Terence A Ketter
    Stanford University School of Medicine, 401 Quarry Road, Room 2124, Stanford, CA, USA
    J Psychiatr Res 43:13-23. 2008
  5. ncbi request reprint Extended-release carbamazepine capsules as monotherapy in bipolar disorder : pooled results from two randomised, double-blind, placebo-controlled trials
    Richard H Weisler
    Department of Psychiatry and Behavioral Science, Duke University, Raleigh, North Carolina 27609, USA
    CNS Drugs 20:219-31. 2006
  6. ncbi request reprint Switching from other agents to extended-release carbamazepine in acute mania
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisvilile School of Medicine, Louisville, KY, USA
    Psychopharmacol Bull 41:52-8. 2008
  7. ncbi request reprint Monotherapy versus combined treatment with second-generation antipsychotics in bipolar disorder
    Terence A Ketter
    Department of Psychiatry and Behavior Sciences and Bipolar Disorders Clinic, Stanford University School of Medicine, 401 Quarry Rd, RM 2124, Stanford, CA 94305 5723, USA
    J Clin Psychiatry 69:9-15. 2008
  8. doi request reprint Toward interaction of affective and cognitive contributors to creativity in bipolar disorders: a controlled study
    Shefali Srivastava
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5723, USA
    J Affect Disord 125:27-34. 2010
  9. doi request reprint Open adjunctive ziprasidone associated with weight loss in obese and overweight bipolar disorder patients
    Po W Wang
    Stanford University School of Medicine, Stanford, CA, USA
    J Psychiatr Res 45:1128-32. 2011
  10. ncbi request reprint Dermatology precautions and slower titration yield low incidence of lamotrigine treatment-emergent rash
    Terence A Ketter
    Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
    J Clin Psychiatry 66:642-5. 2005

Collaborators

Detail Information

Publications90

  1. ncbi request reprint Predictors of treatment response in bipolar disorders: evidence from clinical and brain imaging studies
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Bipolar Disorders Clinic, Stanford University School of Medicine, CA 94305 5273, USA
    J Clin Psychiatry 63:21-5. 2002
    ..Although it is not yet a clinical tool for bipolar disorders, brain imaging provides useful research data to understand the fundamental neurobiology of mood disorders and to more effectively target therapeutics...
  2. ncbi request reprint Stabilization of mood from below versus above baseline in bipolar disorder: a new nomenclature
    Terence A Ketter
    Department of Psychiatry and Behavioral Science, Stanford University School of Medicine, Calif 94305 5723, USA
    J Clin Psychiatry 63:146-51. 2002
    ..In this article, the treatment options for bipolar disorder, with a focus on depression and rapid cycling, are discussed according to this new conceptualization of management from below and above baseline...
  3. doi request reprint Long-term effectiveness of quetiapine in bipolar disorder in a clinical setting
    Terence A Ketter
    Stanford University School of Medicine, Stanford, CA 94305 5723, USA
    J Psychiatr Res 44:921-9. 2010
    ..To assess quetiapine effectiveness in bipolar disorder (BD) patients in a clinical setting...
  4. doi request reprint Effectiveness of lamotrigine in bipolar disorder in a clinical setting
    Terence A Ketter
    Stanford University School of Medicine, 401 Quarry Road, Room 2124, Stanford, CA, USA
    J Psychiatr Res 43:13-23. 2008
    ..To assess lamotrigine effectiveness in bipolar disorder (BD) patients in a clinical setting...
  5. ncbi request reprint Extended-release carbamazepine capsules as monotherapy in bipolar disorder : pooled results from two randomised, double-blind, placebo-controlled trials
    Richard H Weisler
    Department of Psychiatry and Behavioral Science, Duke University, Raleigh, North Carolina 27609, USA
    CNS Drugs 20:219-31. 2006
    ..By pooling data from these two trials, a more highly powered analysis of the efficacy and safety of CBZ-ERC in bipolar I disorder could be conducted...
  6. ncbi request reprint Switching from other agents to extended-release carbamazepine in acute mania
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisvilile School of Medicine, Louisville, KY, USA
    Psychopharmacol Bull 41:52-8. 2008
    ..There is a dearth of available knowledge relating to the efficacy of switching from one psychotropic agent to another in treating patients with acute mania...
  7. ncbi request reprint Monotherapy versus combined treatment with second-generation antipsychotics in bipolar disorder
    Terence A Ketter
    Department of Psychiatry and Behavior Sciences and Bipolar Disorders Clinic, Stanford University School of Medicine, 401 Quarry Rd, RM 2124, Stanford, CA 94305 5723, USA
    J Clin Psychiatry 69:9-15. 2008
    ..The decision to use a combination therapy should be made on the basis of the efficacy, tolerability, and safety of each medication and their specific combination for individual patients...
  8. doi request reprint Toward interaction of affective and cognitive contributors to creativity in bipolar disorders: a controlled study
    Shefali Srivastava
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5723, USA
    J Affect Disord 125:27-34. 2010
    ..Enhanced creativity in bipolar disorder patients may be related to affective and cognitive phenomena...
  9. doi request reprint Open adjunctive ziprasidone associated with weight loss in obese and overweight bipolar disorder patients
    Po W Wang
    Stanford University School of Medicine, Stanford, CA, USA
    J Psychiatr Res 45:1128-32. 2011
    ..To assess effectiveness and tolerability of open adjunctive ziprasidone for weight loss in obese/overweight patients with bipolar disorders (BD) in diverse mood states, taking weight gain-implicated psychotropic medications...
  10. ncbi request reprint Dermatology precautions and slower titration yield low incidence of lamotrigine treatment-emergent rash
    Terence A Ketter
    Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
    J Clin Psychiatry 66:642-5. 2005
    ..To assess treatment-emergent rash incidence when using dermatology precautions (limited antigen exposure) and slower titration during lamotrigine initiation...
  11. ncbi request reprint The effect of dermatologic precautions on the incidence of rash with addition of lamotrigine in the treatment of bipolar I disorder: a randomized trial
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif, USA
    J Clin Psychiatry 67:400-6. 2006
    ..This study assessed the impact of specific instructions designed to decrease risk of dermatologic reactions, including nonserious rash, during initiation of and early treatment with lamotrigine in patients with bipolar I disorder...
  12. ncbi request reprint Extended-release carbamazepine capsules as monotherapy for acute mania in bipolar disorder: a multicenter, randomized, double-blind, placebo-controlled trial
    Richard H Weisler
    Department of Psychiatry and Behavioral Sciences, Duke University, 700 Spring Forest, Suite 125, Raleigh, NC 27609, USA
    J Clin Psychiatry 66:323-30. 2005
    ..In the present study, we further evaluated the efficacy and safety of monotherapy with beaded, extended-release carbamazepine capsules (ERC-CBZ) in patients with bipolar I disorder experiencing manic or mixed episodes...
  13. doi request reprint Enhanced ziprasidone combination therapy effectiveness in obese compared to nonobese patients with bipolar disorder
    Shefali Miller
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5723, USA
    J Clin Psychopharmacol 32:814-9. 2012
    ..To assess longer-term ziprasidone effectiveness in obese and non-obese patients with bipolar disorder (BD)...
  14. doi request reprint Pilot study of the efficacy of double-blind, placebo-controlled one-week olanzapine stabilization therapy in heterogeneous symptomatic bipolar disorder patients
    Shefali Srivastava
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
    J Psychiatr Res 46:920-6. 2012
    ....
  15. ncbi request reprint Enhanced creativity in bipolar disorder patients: a controlled study
    Claudia M Santosa
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305 5723, USA
    J Affect Disord 100:31-9. 2007
    ..We assessed non-eminent creativity in euthymic bipolar (BP) and unipolar major depressive disorder (MDD) patients, creative discipline controls (CC), and healthy controls (HC)...
  16. doi request reprint Gender-specific lipid profiles in patients with bipolar disorder
    Mytilee Vemuri
    Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford, CA 94305 5723, USA
    J Psychiatr Res 45:1036-41. 2011
    ..High rates of dyslipidemia and insulin resistance (IR) are reported in patients with bipolar disorder (BD). We assessed gender effects upon rates of dyslipidemia/IR in outpatients with BD...
  17. ncbi request reprint Differential efficacy of olanzapine and lithium in preventing manic or mixed recurrence in patients with bipolar I disorder based on number of previous manic or mixed episodes
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
    J Clin Psychiatry 67:95-101. 2006
    ..We investigated treatment efficacy in prevention of mood episodes in patients subgrouped by number of prior manic episodes...
  18. ncbi request reprint A 6-month, multicenter, open-label evaluation of beaded, extended-release carbamazepine capsule monotherapy in bipolar disorder patients with manic or mixed episodes
    Terence A Ketter
    Stanford University School of Medicine, Stanford, California 94305 5723, USA
    J Clin Psychiatry 65:668-73. 2004
    ..We evaluated open-label monotherapy with beaded extended-release carbamazepine capsules (ERC-CBZ; SPD417) as continuation and short-term maintenance therapy in bipolar disorder patients with manic and mixed episodes...
  19. ncbi request reprint Temperament-creativity relationships in mood disorder patients, healthy controls and highly creative individuals
    Connie M Strong
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Room 2124, Stanford, CA 94305 5723, USA
    J Affect Disord 100:41-8. 2007
    ..To investigate temperament-creativity relationships in euthymic bipolar (BP) and unipolar major depressive (MDD) patients, creative discipline controls (CC), and healthy controls (HC)...
  20. ncbi request reprint Adjunctive aripiprazole in treatment-resistant bipolar depression
    Terence A Ketter
    Stanford University School of Medicine, Stanford, CA, USA
    Ann Clin Psychiatry 18:169-72. 2006
    ..There are limited management options for treatment-resistant depression in bipolar disorder (BD) patients...
  21. doi request reprint Clinical relevance of treatments for acute bipolar disorder: balancing therapeutic and adverse effects
    Shefali Srivastava
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    Clin Ther 33:B40-8. 2011
    ..These agents differ from one another with respect to their efficacy and tolerability profiles, such that certain medications may be optimal for some patients but not others...
  22. pmc Metabolic dysfunction in women with bipolar disorder: the potential influence of family history of type 2 diabetes mellitus
    Natalie L Rasgon
    Stanford Center for Neuroscience in Women s Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5723, USA
    Bipolar Disord 12:504-13. 2010
    ..Family history of type 2 diabetes mellitus (FamHxDM2), which has been shown to have deleterious effects on metabolic function in the general population, may play a role in the metabolic dysfunction observed in BD...
  23. ncbi request reprint The emerging differential roles of GABAergic and antiglutamatergic agents in bipolar disorders
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Calif 94305, USA
    J Clin Psychiatry 64:15-20. 2003
    ..We review the efficacy and tolerability of these diverse treatment options in bipolar disorders and explore possible relationships between clinical effects and GABAergic and antiglutamatergic mechanisms of action...
  24. ncbi request reprint Rates of remission/euthymia with quetiapine monotherapy compared with placebo in patients with acute mania
    Terence A Ketter
    Stanford University, Department of Psychiatry and Behavioral Sciences, Stanford, California 94305 5723, USA
    J Affect Disord 100:S45-53. 2007
    ..To evaluate the effects of quetiapine monotherapy compared with placebo on acute (3-week) and more sustained (12-week) rates of response and remission/euthymia in bipolar disorder patients with acute mania...
  25. ncbi request reprint New anticonvulsant medication uses in bipolar disorder
    Po W Wang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California, USA
    CNS Spectr 8:930-2, 941-7. 2003
    ....
  26. pmc Evaluation of reproductive function in women treated for bipolar disorder compared to healthy controls
    Margaret F Reynolds-May
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
    Bipolar Disord 16:37-47. 2014
    ..The purpose of the present study was to investigate the reproductive function of women with bipolar disorder (BD) compared to healthy controls...
  27. ncbi request reprint Psychotic bipolar disorders: dimensionally similar to or categorically different from schizophrenia?
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Bipolar Disorders Clinic, Room 2124, 401 Quarry Road, Stanford, CA 94305 5723, USA
    J Psychiatr Res 38:47-61. 2004
    ....
  28. pmc Brain-derived neurotrophic factor val66met genotype and early life stress effects upon bipolar course
    Shefali Miller
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, USA
    J Psychiatr Res 47:252-8. 2013
    ..We examined effects of brain-derived neurotrophic factor (BDNF) val66met genotype and early life stress (ELS) upon illness severity and chronicity in adult BD patients...
  29. ncbi request reprint Combination therapy versus monotherapy in bipolar disorder
    Terence A Ketter
    Department of Psychiatry and Behavior Sciences and Bipolar Disorders Clinic, Stanford University School of Medicine, Stanford, Calif, USA
    J Clin Psychiatry 69:e34. 2008
    ..Psychosocial therapy as an adjunct to medication is also useful in delaying relapse...
  30. ncbi request reprint Creativity in familial bipolar disorder
    Diana I Simeonova
    Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, Stanford, CA 94305 5540, USA
    J Psychiatr Res 39:623-31. 2005
    ....
  31. ncbi request reprint Safety and efficacy of anticonvulsants in elderly patients with psychiatric disorders: oxcarbazepine, topiramate and gabapentin
    Barbara R Sommer
    Stanford University School of Medicine, Department of Psychiatry, Stanford, CA 94305 5723, USA
    Expert Opin Drug Saf 6:133-45. 2007
    ..5-10.5 h, may cause ataxia. Oxcarbazapine, hepatically reduced, may cause hyponatremia, and topiramate may cause significant cognitive impairment. Nonetheless, these are important medications to consider in the treatment of agitation...
  32. doi request reprint Rapid antipsychotic response with ziprasidone predicts subsequent acute manic/mixed episode remission
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305 5723, USA
    J Psychiatr Res 44:8-14. 2010
    ..To assess rapid antipsychotic efficacy with oral ziprasidone monotherapy in bipolar acute manic/mixed episodes with psychotic features, and predictive value of rapid antipsychotic response for subsequent acute manic/mixed episode remission...
  33. doi request reprint First controlled treatment trial of bipolar II hypomania with mixed symptoms: quetiapine versus placebo
    Trisha Suppes
    Department of Psychiatry and Behavioral Sciences, Stanford University, School of Medicine, Stanford, CA, USA
    J Affect Disord 150:37-43. 2013
    ....
  34. ncbi request reprint Mood stabilizers and atypical antipsychotics: bimodal treatments for bipolar disorder
    Terence A Ketter
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Psychopharmacol Bull 39:120-46. 2006
    ..Further investigation of combinations of agents such as mood stabilizers and atypical antipsychotics may yield valuable insights into the potential of combination therapies to enhance clinical outcomes in patients with bipolar disorder...
  35. ncbi request reprint Gabapentin augmentation therapy in bipolar depression
    Po W Wang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5723, USA
    Bipolar Disord 4:296-301. 2002
    ..Gabapentin (GBP) may be useful in bipolar disorders, including as adjunctive therapy for bipolar depression, although controlled studies suggest inefficacy as primary treatment for mania or treatment-resistant rapid cycling...
  36. ncbi request reprint Olanzapine in diverse syndromal and subsyndromal exacerbations of bipolar disorders
    Suttiporn Janenawasin
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5723, USA
    Bipolar Disord 4:328-34. 2002
    ..To evaluate effects of olanzapine in diverse exacerbations of bipolar disorders...
  37. ncbi request reprint A multicenter, randomized, double-blind, placebo-controlled trial of extended-release carbamazepine capsules as monotherapy for bipolar disorder patients with manic or mixed episodes
    Richard H Weisler
    Department of Psychiatry and Behavioral Science, Duke University, 700 Spring Forest, Suite 125, Raleigh, N C 27609, USA
    J Clin Psychiatry 65:478-84. 2004
    ..We assessed the efficacy and safety of monotherapy with beaded, extended-release carbamazepine capsules (ERC-CBZ; SPD417) in bipolar disorder patients with manic or mixed episodes...
  38. doi request reprint The link between bipolar disorders and creativity: evidence from personality and temperament studies
    Shefali Srivastava
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305, USA
    Curr Psychiatry Rep 12:522-30. 2010
    ....
  39. ncbi request reprint Temperamental commonalities and differences in euthymic mood disorder patients, creative controls, and healthy controls
    Cecylia Nowakowska
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Room 2350, Stanford, CA 94305 5723, USA
    J Affect Disord 85:207-15. 2005
    ..We explored temperamental commonalities and differences among euthymic bipolar (BP) and unipolar (MDD) mood disorder patients, creative discipline graduate student controls (CC), and healthy controls (HC)...
  40. pmc Blood levels of brain derived neurotrophic factor in women with bipolar disorder and healthy control women
    Heather A Kenna
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Rd MC 5723, Stanford, CA 94305 5723, United States
    J Affect Disord 156:214-8. 2014
    ..BDNF polymorphism, val66met, has also been implicated in mood disorders...
  41. pmc Atypical antipsychotics for acute manic and mixed episodes in children and adolescents with bipolar disorder: efficacy and tolerability
    Manpreet K Singh
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    Drugs 70:433-42. 2010
    ..Additional longitudinal and biological studies are warranted to characterize the effects of atypical antipsychotics on all phases and stages of bipolar illness development in children and adolescents...
  42. ncbi request reprint Bupropion and venlafaxine responders differ in pretreatment regional cerebral metabolism in unipolar depression
    John T Little
    Division of Psychiatric Neuroimaging, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Biol Psychiatry 57:220-8. 2005
    ..Pretreatment functional brain imaging was examined for never-hospitalized outpatients with unipolar depression compared with control subjects in a crossover treatment trial involving bupropion or venlafaxine monotherapy...
  43. ncbi request reprint Perceptions of weight gain and bipolar pharmacotherapy: results of a 2005 survey of physicians in clinical practice
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5723, USA
    Curr Med Res Opin 22:2345-53. 2006
    ..To assess the perceptions of clinicians in the psychiatric community about pharmacotherapy and its impact on weight gain and adverse metabolic effects in patients with bipolar disorder...
  44. ncbi request reprint Overweight and obesity in bipolar disorders
    Po W Wang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Room 2117, CA 94305 5723, USA
    J Psychiatr Res 40:762-4. 2006
  45. ncbi request reprint Treating bipolar disorder: monotherapy versus combination therapy
    Terence A Ketter
    Department of Psychiatry and Behavior Sciences and the Bipolar Disorders Clinic, Stanford University School of Medicine, Stanford, CA, USA
    J Clin Psychiatry 70:e42. 2009
    ..Physicians should exercise caution when treating patients with a combination of medications and strive to use monotherapy when feasible...
  46. ncbi request reprint The diverse roles of anticonvulsants in bipolar disorders
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5723, USA
    Ann Clin Psychiatry 15:95-108. 2003
    ..The categorical-mechanistic extension strives to address this issue, but requires systematic clinical investigation of more precise relationships between psychotropic profiles and discrete mechanisms of action to assess its merits...
  47. ncbi request reprint Lamotrigine plus quetiapine combination therapy in treatment-resistant bipolar depression
    Yong M Ahn
    Department of Neuropsychiatry, Seoul National University Hospital, Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Chongno Gu, Seoul, Republic of Korea
    Ann Clin Psychiatry 23:17-24. 2011
    ..Lamotrigine and quetiapine are commonly used in bipolar disorder, but there are no published systematic studies of their use in combination for treatment-resistant bipolar depression...
  48. ncbi request reprint Adjunctive zonisamide for weight loss in euthymic bipolar disorder patients: a pilot study
    Po W Wang
    Stanford University School of Medicine, 401 Quarry Road, Suite 2117, Stanford, CA 94305 5723, United States
    J Psychiatr Res 42:451-7. 2008
    ..To assess the effectiveness and tolerability of open adjunctive zonisamide in treatment of obesity in euthymic bipolar disorder (BD) patients...
  49. ncbi request reprint Preliminary evidence of differential relations between prefrontal cortex metabolism and sustained attention in depressed adults with bipolar disorder and healthy controls
    John O Brooks
    Palo Alto Veterans Affairs Health Care System, Palo Alto, CA 94304, USA
    Bipolar Disord 8:248-54. 2006
    ..To assess the relations between sustained attention as assessed by the Continuous Performance Test (CPT) and subgenual and dorsolateral prefrontal cortex metabolism in depressed patients with bipolar disorders and healthy controls...
  50. ncbi request reprint Impaired recognition of facial emotion in mania
    Anna Lembke
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305 5723, USA
    Am J Psychiatry 159:302-4. 2002
    ..Recognition of facial emotion was examined in manic subjects to explore whether aberrant interpersonal interactions are related to impaired perception of social cues...
  51. ncbi request reprint Assessing efficacy/effectiveness and safety/tolerability profiles of adjunctive pramipexole in bipolar depression: acute versus long-term data
    Bernardo Dell'Osso
    aDepartment of Psychiatry, University of Milan, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milan, Italy bDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    Int Clin Psychopharmacol 28:297-304. 2013
    ..Adjunctive pramipexole may be a valid option in both the acute and the long-term treatment of drug-resistant bipolar depression, with possible superior tolerability in the short term. ..
  52. doi request reprint Trends in pharmacotherapy in patients referred to a bipolar specialty clinic, 2000-2011
    Farnaz Hooshmand
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5723, USA
    J Affect Disord 155:283-7. 2014
    ..To assess mood stabilizer (MS) and second-generation antipsychotic (SGA) prescribing trends in bipolar disorder (BD) outpatients referred to a bipolar disorder specialty clinic over the past 12 years...
  53. ncbi request reprint Psychosocial service utilization by patients with bipolar disorders: data from the first 500 participants in the Systematic Treatment Enhancement Program
    Anna Lembke
    Stanford University School of Medicine, CA, USA
    J Psychiatr Pract 10:81-7. 2004
    ..We set out to clarify the determinants of psychosocial service utilization in adults with bipolar disorder...
  54. ncbi request reprint Pharmacokinetics of mood stabilizers and new anticonvulsants
    Po W Wang
    Department of Psychiatry and Behavioral Sciences, Bipolar Disorders Clinic, Stanford University School of Medicine, 401 Quarry Road, Room 2117, Stanford, CA 94305 5723, USA
    Psychopharmacol Bull 36:44-66. 2002
    ..Novel psychotropic effects of these drugs may also be demonstrated, based on their mechanisms of action and preliminary clinical data...
  55. ncbi request reprint Clinical use of carbamazepine for bipolar disorders
    Po W Wang
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, CA, USA
    Expert Opin Pharmacother 6:2887-902. 2005
    ..This paper reviews the chemistry, pharmacodynamics and pharmacokinetics of CBZ, as well as reviews of the controlled trials of CBZ in acute bipolar mania, acute bipolar depression and bipolar maintenance treatment...
  56. ncbi request reprint Temperament characteristics of child and adolescent bipolar offspring
    Kiki D Chang
    Department of Psychiatry and Behavioral Sciences, Division of Child Psychiatry and Child Development, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 5719, USA
    J Affect Disord 77:11-9. 2003
    ..We wished to characterize temperament of children at high risk for bipolar disorder (BD)...
  57. ncbi request reprint Increased frequency of depressive episodes during the menopausal transition in women with bipolar disorder: preliminary report
    Wendy K Marsh
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, United States
    J Psychiatr Res 42:247-51. 2008
    ..The menopausal transition in women without mood disorders is associated with an increase in depression. This study assesses mood course during the menopausal transition in women with bipolar disorder...
  58. ncbi request reprint Incorporating trial data into bipolar disorder management
    Terence A Ketter
    Department of Psychiatry, Stanford University School of Medicine, Stanford, California, USA
    J Clin Psychiatry 69:e21. 2008
    ..These interventions, combined with judicious pharmacotherapy, can help minimize the impact of adverse effects and related nonadherence so that patients can achieve affective stability, regain psychosocial function, and maintain health...
  59. ncbi request reprint Potential mechanisms of action of lamotrigine in the treatment of bipolar disorders
    Terence A Ketter
    Bipolar Disorders Clinic, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
    J Clin Psychopharmacol 23:484-95. 2003
    ..Although lamotrigine mechanisms overlap those of other mood-stabilizing anticonvulsants, important dissociations suggest candidate mechanisms, which could contribute to lamotrigine's distinctive psychotropic profile...
  60. doi request reprint Nosology, diagnostic challenges, and unmet needs in managing bipolar disorder
    Terence A Ketter
    Bipolar Disorders Clinic, Department of Psychiatry and Behavioral Science, Stanford University School of Medicine, Stanford, California, USA
    J Clin Psychiatry 71:e27. 2010
    ..Unmet needs in the management of bipolar disorder include an enhanced diagnostic process, more options for treating bipolar depressive episodes, and safer, more tolerable medications for long-term maintenance treatment...
  61. ncbi request reprint Strategies for the early recognition of bipolar disorder
    Terence A Ketter
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    J Clin Psychiatry 72:e22. 2011
    ..This activity describes various risk factors for the development of bipolar disorder and discusses possible solutions to the challenges surrounding timely diagnosis...
  62. ncbi request reprint Regional cerebral glucose utilization in patients with a range of severities of unipolar depression
    Tim A Kimbrell
    North Little Rock VA Medical Center TAKi, North Little Rock, Arkansas, USA
    Biol Psychiatry 51:237-52. 2002
    ....
  63. ncbi request reprint Lamotrigine treatment of bipolar disorder: data from the first 500 patients in STEP-BD
    Lauren B Marangell
    Mood Disorders Program, Department of Psychiatry, Baylor College of Medicine, Houston, TX 77030, USA
    Bipolar Disord 6:139-43. 2004
    ..To describe the frequency and correlates of lamotrigine therapy among the first 500 patients enrolled into the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study...
  64. ncbi request reprint Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Arch Gen Psychiatry 60:1079-88. 2003
    ....
  65. ncbi request reprint Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders
    Gabriela V Obrocea
    National Institute of Mental Health, Biological Psychiatry Branch, Bethesda, Maryland 20892, USA
    Biol Psychiatry 51:253-60. 2002
    ..The objective of the current study was to examine possible clinical predictors of positive response to lamotrigine or gabapentin monotherapy in treatment-refractory affectively ill patients...
  66. ncbi request reprint Age, sex and laterality effects on cerebral glucose metabolism in healthy adults
    Mark W Willis
    Biological Psychiatry Branch, National Institute of Mental Health, 10 Center Drive MSC 1272, Bethesda, MD 20892 1272, USA
    Psychiatry Res 114:23-37. 2002
    ..These findings contribute toward a convergence in the literature, and the regression models of CMRglc vs. age serve as a normative database to which patients may be compared...
  67. ncbi request reprint Principal components of the Beck Depression Inventory and regional cerebral metabolism in unipolar and bipolar depression
    Robert T Dunn
    Biological Psychiatry Branch, NIMH, NIH, Bethesda, Maryland 20892 1272, USA
    Biol Psychiatry 51:387-99. 2002
    ..Then, comparing unipolars and bipolars, these symptom clusters were examined for interrelationships, and for relationships to regional cerebral metabolism for glucose measured by positron emission tomography...
  68. ncbi request reprint Synaptic, intracellular, and neuroprotective mechanisms of anticonvulsants: are they relevant for the treatment and course of bipolar disorders?
    Xiaohua Li
    Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294 4400, USA
    J Affect Disord 69:1-14. 2002
    ..Understanding the mechanisms of anticonvulsant mood stabilizers, integrated with clinical observations, may ultimately provide important new insights into the pathophysiology and treatment of bipolar disorders...
  69. ncbi request reprint Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study
    Mauricio Tohen
    Lilly Research Laboratories, IN 46285, USA
    Am J Psychiatry 160:1263-71. 2003
    ..Few double-blind trials have compared longer-term efficacy and safety of medications for bipolar disorder. The authors report a 47-week comparison of olanzapine and divalproex...
  70. ncbi request reprint Recurrence in bipolar I disorder: a post hoc analysis excluding relapses in two double-blind maintenance studies
    Joseph R Calabrese
    Department of Psychiatry, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    Biol Psychiatry 59:1061-4. 2006
    ..To assess the efficacy of lamotrigine or lithium in preventing mood recurrence (i.e., a new mood episode) in bipolar disorder...
  71. ncbi request reprint Phenomenology of rapid-cycling bipolar disorder: data from the first 500 participants in the Systematic Treatment Enhancement Program
    Christopher D Schneck
    Department of Psychiatry, University of Colorado Health Sciences Center, 4455 East 12th Ave, Box A011 15, Denver, CO 80220, USA
    Am J Psychiatry 161:1902-8. 2004
    ..This study compared demographic and phenomenological variables between bipolar patients with and without rapid cycling as a function of bipolar I versus bipolar II status...
  72. ncbi request reprint Efficacy of olanzapine combined with valproate or lithium in the treatment of dysphoric mania
    Robert W Baker
    Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Br J Psychiatry 185:472-8. 2004
    ..Few controlled studies examine the treatment of depressive features in mania...
  73. ncbi request reprint Analyses of treatment-emergent mania with olanzapine/fluoxetine combination in the treatment of bipolar depression
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:611-6. 2005
    ..These subanalyses compare treatment-emergent mania rates in bipolar I depressed patients treated with olanzapine, placebo, or olanzapine/fluoxetine combination...
  74. ncbi request reprint The use of antiepileptic drugs in bipolar disorders: a review based on evidence from controlled trials
    Richard H Weisler
    University of North Carolina at Chapel Hill, NC, USA
    CNS Spectr 11:788-99. 2006
    ..This article provides an overview of data on the use of AEDs in bipolar disorder, including acute mania and depression, prophylaxis, and rapid cycling...
  75. ncbi request reprint Carbamazepine and valproate for the treatment of bipolar disorder: a review of the literature
    Henry A Nasrallah
    Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45267 0559, USA
    J Affect Disord 95:69-78. 2006
    ..Controlled and direct comparative studies, both short and long term, are needed to further clarify the differences between VPA and CBZ...
  76. ncbi request reprint Impact of lamotrigine and lithium on weight in obese and nonobese patients with bipolar I disorder
    Charles L Bowden
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229 3900, USA
    Am J Psychiatry 163:1199-201. 2006
    ..This study assessed weight changes in a large cohort of patients with bipolar disorder who were treated with randomly assigned maintenance monotherapies...
  77. ncbi request reprint Incidence and time course of subsyndromal symptoms in patients with bipolar I disorder: an evaluation of 2 placebo-controlled maintenance trials
    Mark A Frye
    Mood Disorders Research Program, University of California at Los Angeles, USA
    J Clin Psychiatry 67:1721-8. 2006
    ..Subsyndromal symptoms in bipolar disorder can cause significant functional impairment and are associated with relapse...
  78. ncbi request reprint Safety and tolerability of mood-stabilising anticonvulsants in the elderly
    Howard H Fenn
    Menlo Park Division, Palo Alto Veterans Affairs Healthcare System, Menlo Park, California 94025, USA
    Expert Opin Drug Saf 5:401-16. 2006
    ..Guidelines are offered for the safe use of these medications in the elderly, based on research literature...
  79. ncbi request reprint Preliminary findings of uncoupling of flow and metabolism in unipolar compared with bipolar affective illness and normal controls
    Robert T Dunn
    Biological Psychiatry Branch, National Institute of Mental Health, NIH, 10 Center Drive MSC 1272, Bethesda, MD 20892 1272, USA
    Psychiatry Res 140:181-98. 2005
    ....
  80. ncbi request reprint Number needed to treat and time to response/remission for quetiapine monotherapy efficacy in acute bipolar depression: evidence from a large, randomized, placebo-controlled study
    John Cookson
    The Department of Psychiatry, Royal London Hospital, London, UK
    Int Clin Psychopharmacol 22:93-100. 2007
    ..2%, quetiapine 300 mg/day: 3.9, and placebo: 3.9%). In conclusion, quetiapine compared with placebo significantly reduces time to response and remission compared with placebo, and has a favorable number needed to treat...
  81. ncbi request reprint Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
    Roy H Perlis
    Bipolar Clinical and Research Program, Massachusetts General Hospital, ACC 812, 15 Parkman Street, Boston, MA 02114, USA
    Am J Psychiatry 163:217-24. 2006
    ..The authors looked for the features associated with risk of recurrence...
  82. ncbi request reprint Treatment-resistant bipolar depression: a STEP-BD equipoise randomized effectiveness trial of antidepressant augmentation with lamotrigine, inositol, or risperidone
    Andrew A Nierenberg
    Massachusetts General Hospital Bipolar Clinic and Research Program, Suite 580, 50 Staniford Street, Boston, MA 02114, USA
    Am J Psychiatry 163:210-6. 2006
    ..This study represents the first randomized trial of competing options for treatment-resistant bipolar depression and assesses the effectiveness and safety of antidepressant augmentation with lamotrigine, inositol, and risperidone...
  83. ncbi request reprint Introduction - advancing understanding of the effectiveness of quetiapine in acute mania
    Terence A Ketter
    J Affect Disord 100:S1-3. 2007
  84. ncbi request reprint Effectiveness of adjunctive antidepressant treatment for bipolar depression
    Gary S Sachs
    Bipolar Clinic and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    N Engl J Med 356:1711-22. 2007
    ..Our study was designed to determine whether adjunctive antidepressant therapy reduces symptoms of bipolar depression without increasing the risk of mania...
  85. ncbi request reprint Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder
    Joseph F Goldberg
    Affective Disorders Program, Silver Hill Hospital, New Canaan, Connecticut 06840, USA
    Biol Psychiatry 63:125-30. 2008
    ..The anticonvulsant lamotrigine has demonstrated efficacy for relapse prevention in bipolar disorder, but its possible mood-stabilizing properties on a day-to-day or week-to-week basis have not previously been investigated...
  86. ncbi request reprint Focus on bipolar disorder treatment
    Charles L Bowden
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, TX, USA
    J Clin Psychiatry 66:1598-609. 2005
  87. ncbi request reprint Reassessing carbamazepine in the treatment of bipolar disorder: clinical implications of new data
    Hagop S Akiskal
    University of California, San Diego, USA
    CNS Spectr 10:suppl 1-11; discuss 12-3; quiz 14-5. 2005
    ..Further efforts are needed to update physicians on the use of carbamazepine relative to other medications in the treatment of bipolar disorder...
  88. ncbi request reprint The Texas implementation of medication algorithms: update to the algorithms for treatment of bipolar I disorder
    Trisha Suppes
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9121, USA
    J Clin Psychiatry 66:870-86. 2005
    ..The guidelines for evaluating possible medications, the criteria for selection and ranking, and the updated algorithms are described...
  89. ncbi request reprint A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression
    Joseph R Calabrese
    University Hospitals of Cleveland and Case University School of Medicine, 11400 Euclid Ave, Suite 200, Cleveland, OH 44106, USA
    Am J Psychiatry 162:1351-60. 2005
    ..There is a major unmet need for effective options in the treatment of bipolar depression...
  90. ncbi request reprint Omega-3 fatty acids in bipolar disorder: clinical and research considerations
    Lauren B Marangell
    Mood Disorders Center, Menninger Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA
    Prostaglandins Leukot Essent Fatty Acids 75:315-21. 2006
    ..Our pilot trial of DHA in women who plan to stop conventional psychotropics in order to conceive suggests that such trials are feasible...