Research Topics
| G A KerchnerSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Amyloid imaging for Alzheimer's diseaseGeoffrey A Kerchner
Stanford University School of Medicine, Stanford Center for Memory Disorders, Department of Neurology and Neurological Sciences, 300 Pasteur Drive, Room A343, MC5235, Stanford, W CA 94305 5235, USA 1 650 723 2078 1 650 723 7434
Expert Opin Med Diagn 5:527-38. 2011..However, fundamental questions about the role of Aβ in AD must be answered before the full potential of amyloid imaging can be realized...
Cognitive processing speed in older adults: relationship with white matter integrityGeoffrey A Kerchner
Stanford Center for Memory Disorders, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, United States of America
PLoS ONE 7:e50425. 2012..In a statistical mediation analysis, loss of white matter integrity mediated the relationship between age and cognitive processing speed...
Novel presenilin-1 Y159F sequence variant associated with early-onset Alzheimer's diseaseGeoffrey A Kerchner
Stanford Center for Memory Disorders and Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
Neurosci Lett 531:142-4. 2012..Mutations in the gene for presenilin-1 cause familial, early-onset Alzheimer's disease...
Hippocampal CA1 apical neuropil atrophy and memory performance in Alzheimer's diseaseGeoffrey A Kerchner
Stanford Center for Memory Disorders, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
Neuroimage 63:194-202. 2012..These findings highlight a role for 7T hippocampal microstructural imaging in revealing focal structural pathology that correlates with the central cognitive feature of AD...
Hippocampal CA1 apical neuropil atrophy in mild Alzheimer disease visualized with 7-T MRIG A Kerchner
Stanford Center for Memory Disorders, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305 5235, USA
Neurology 75:1381-7. 2010..In this cross-sectional study, we tested whether tissue loss in the CA1 apical neuropil layer can be observed in vivo in patients with mild AD...
Abhorring the vacuum: use of Alzheimer’s disease medications in frontotemporal dementiaGeoffrey A Kerchner
Stanford Center for Memory Disorders, Stanford University Medical Center, 300 Pasteur Drive, Room A343, Stanford, CA 94305 5235, USA
Expert Rev Neurother 11:709-17. 2011..Finally, we discuss our view that such approaches will probably become supplanted by rational, molecularly-based therapies currently in development...
Ultra-high field 7T MRI: a new tool for studying Alzheimer's diseaseGeoffrey A Kerchner
Department of Neurology and Neurological Sciences, Stanford Center for Memory Disorders, Stanford University School of Medicine, Stanford, CA 94305 5235, USA
J Alzheimers Dis 26:91-5. 2011..I also discuss limitations of this technology as well as expected advances that are likely to establish 7T MRI as an increasingly important tool for the diagnosis and tracking of AD...
