Peter Kao

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells
    Lingfang Shi
    Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305 5236, USA
    Nucleic Acids Res 35:2302-10. 2007
  2. pmc NF90 regulates inducible IL-2 gene expression in T cells
    Lingfang Shi
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    J Exp Med 204:971-7. 2007
  3. pmc Aerosolized amikacin for treatment of pulmonary Mycobacterium avium infections: an observational case series
    Kala K Davis
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA, USA
    BMC Pulm Med 7:2. 2007
  4. ncbi request reprint Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f
    Daoming Qiu
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, California 94305, USA
    Drugs R D 4:1-18. 2003
  5. ncbi request reprint Simvastatin treatment of pulmonary hypertension: an observational case series
    Peter N Kao
    Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305 5236, USA
    Chest 127:1446-52. 2005
  6. ncbi request reprint Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats
    Laszlo T Vaszar
    Division of Pulmonary Critical Care Medicine, Stanford University Medical Center, Stanford, California 94305 5236, USA
    Physiol Genomics 17:150-6. 2004
  7. ncbi request reprint Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells
    Toshihiko Nishimura
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, Calif 94305 5236, USA
    Circulation 108:1640-5. 2003
  8. ncbi request reprint Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats
    Toshihiko Nishimura
    Division of Pulmonary and Critical Care Medicine, and Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA
    Am J Respir Crit Care Med 166:1403-8. 2002
  9. ncbi request reprint Simvastatin enhances bone morphogenetic protein receptor type II expression
    Hong Hu
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305 5236, USA
    Biochem Biophys Res Commun 339:59-64. 2006
  10. ncbi request reprint Effect of a surgical aortocaval fistula on monocrotaline-induced pulmonary hypertension
    Toshihiko Nishimura
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, 300 Pasteur Avenue, Stanford, CA 94305, USA
    Crit Care Med 31:1213-8. 2003

Research Grants

  1. T-Cells in Lung Inflammation
    Peter N Kao; Fiscal Year: 2010
  2. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2009
  3. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2007
  4. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2005
  5. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2004
  6. EPITHELIAL CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2003
  7. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2003
  8. EPITHELIAL CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2002
  9. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2002
  10. EPITHELIAL CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2001

Collaborators

Detail Information

Publications13

  1. pmc Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells
    Lingfang Shi
    Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305 5236, USA
    Nucleic Acids Res 35:2302-10. 2007
    ..Dynamic changes in binding of Ku80, Ku70 and NF90 to the IL-2 proximal promoter in vivo correlate with chromatin remodeling and transcriptional initiation in activated T-cells...
  2. pmc NF90 regulates inducible IL-2 gene expression in T cells
    Lingfang Shi
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    J Exp Med 204:971-7. 2007
    ..Thus, NF90 regulates inducible IL-2 transcription, mRNA stability, and gene expression in T cells and represents a novel therapeutic target for the modulation of T cell immune responses...
  3. pmc Aerosolized amikacin for treatment of pulmonary Mycobacterium avium infections: an observational case series
    Kala K Davis
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA, USA
    BMC Pulm Med 7:2. 2007
    ..This study was undertaken to assess the safety, tolerability and preliminary clinical benefits of the addition of aerosolized amikacin to a standard macrolide-based oral treatment regimen...
  4. ncbi request reprint Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f
    Daoming Qiu
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, California 94305, USA
    Drugs R D 4:1-18. 2003
    ..Further characterisation of the molecular mechanisms of triptolide action will serve to elucidate pathways of immune system regulation...
  5. ncbi request reprint Simvastatin treatment of pulmonary hypertension: an observational case series
    Peter N Kao
    Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305 5236, USA
    Chest 127:1446-52. 2005
    ..In pneumonectomized rats injected with monocrotaline, simvastatin reversed established pulmonary hypertension and conferred a 100% survival advantage...
  6. ncbi request reprint Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats
    Laszlo T Vaszar
    Division of Pulmonary Critical Care Medicine, Stanford University Medical Center, Stanford, California 94305 5236, USA
    Physiol Genomics 17:150-6. 2004
    ..Mast-cell-derived proteases may play a role in regulating the development of neointimal pulmonary vascular occlusion and pulmonary hypertension in response to injury...
  7. ncbi request reprint Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells
    Toshihiko Nishimura
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, Calif 94305 5236, USA
    Circulation 108:1640-5. 2003
    ..The present study was undertaken to investigate the efficacy of simvastatin and its mechanism of reversing established neointimal vascular occlusion and pulmonary hypertension...
  8. ncbi request reprint Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats
    Toshihiko Nishimura
    Division of Pulmonary and Critical Care Medicine, and Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA
    Am J Respir Crit Care Med 166:1403-8. 2002
    ..Simvastatin attenuates monocrotaline-induced pulmonary vascular remodeling with neointimal formation, pulmonary arterial hypertension, and right ventricular hypertrophy in rats...
  9. ncbi request reprint Simvastatin enhances bone morphogenetic protein receptor type II expression
    Hong Hu
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305 5236, USA
    Biochem Biophys Res Commun 339:59-64. 2006
    ..Simvastatin induction of BMPR2 expression may improve BMP-BMPR2 signaling thereby enhancing endothelial differentiation and function...
  10. ncbi request reprint Effect of a surgical aortocaval fistula on monocrotaline-induced pulmonary hypertension
    Toshihiko Nishimura
    Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, 300 Pasteur Avenue, Stanford, CA 94305, USA
    Crit Care Med 31:1213-8. 2003
    ..We investigated the effect of overcirculation via an aortocaval fistula, on the development of monocrotaline-induced pulmonary hypertension in rats. Monocrotaline was administered 1 wk after the creation of an aortocaval fistula...
  11. ncbi request reprint High prevalence of autoimmune thyroid disease in pulmonary arterial hypertension
    James W Chu
    Divisions of Endocrinology and Metabolism, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5236, USA
    Chest 122:1668-73. 2002
    ..Because immune system dysfunction may underlie this association, we sought to determine the prevalence of autoimmune thyroid disease (AITD) in patients with PAH...
  12. ncbi request reprint Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop
    John H Newman
    Departments of Medicine, Nashville VA Medical Center GRECC, and Vanderbilt University, Nashville, Tenn, USA
    Circulation 109:2947-52. 2004
  13. ncbi request reprint Emerging therapies for pulmonary hypertension: striving for efficacy and safety
    Peter N Kao
    J Am Coll Cardiol 41:2126-9. 2003

Research Grants18

  1. T-Cells in Lung Inflammation
    Peter N Kao; Fiscal Year: 2010
    ..Further molecular insights into the regulation of IL-2 gene expression in activated T-cells will identify novel targets and strategies for therapeutic manipulation of T-cell immune responses in disease. ..
  2. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2009
    ..Further molecular insights into the regulation of IL-2 gene expression in activated T-cells will identify novel targets and strategies for therapeutic manipulation of T-cell immune responses in disease. ..
  3. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2007
    ..Further molecular insights into the regulation of IL-2 gene expression in activated T-cells will identify novel targets and strategies for therapeutic manipulation of T-cell immune responses in disease. ..
  4. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2005
    ..Increased understanding of T-cell activation and its modulation by immunosuppressant drugs will guide future therapies for lung inflammation, autoimmune diseases, cancer and AIDS. ..
  5. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2004
    ..Increased understanding of T-cell activation and its modulation by immunosuppressant drugs will guide future therapies for lung inflammation, autoimmune diseases, cancer and AIDS. ..
  6. EPITHELIAL CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2003
    ..A signaling enzyme in HBE cells which is specifically inactivated by PG490 and which regulates NF-kappaB transcriptional activation in the nucleus will be isolated and characterized. ..
  7. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2003
    ..Increased understanding of T-cell activation and its modulation by immunosuppressant drugs will guide future therapies for lung inflammation, autoimmune diseases, cancer and AIDS. ..
  8. EPITHELIAL CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2002
    ..A signaling enzyme in HBE cells which is specifically inactivated by PG490 and which regulates NF-kappaB transcriptional activation in the nucleus will be isolated and characterized. ..
  9. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2002
    ..Increased understanding of T-cell activation and its modulation by immunosuppressant drugs will guide future therapies for lung inflammation, autoimmune diseases, cancer and AIDS. ..
  10. EPITHELIAL CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2001
    ..A signaling enzyme in HBE cells which is specifically inactivated by PG490 and which regulates NF-kappaB transcriptional activation in the nucleus will be isolated and characterized. ..
  11. T-Cells in Lung Inflammation
    Peter Kao; Fiscal Year: 2001
    ..Increased understanding of T-cell activation and its modulation by immunosuppressant drugs will guide future therapies for lung inflammation, autoimmune diseases, cancer and AIDS. ..
  12. T CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2000
    ..Understanding T-cell cytokine expression and its modulation by immunosuppressant drugs and viral transactivating proteins will guide future therapies of lung inflammation. ..
  13. EPITHELIAL CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2000
    ..A signaling enzyme in HBE cells which is specifically inactivated by PG490 and which regulates NF-kappaB transcriptional activation in the nucleus will be isolated and characterized. ..
  14. T CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 1999
    ..Understanding T-cell cytokine expression and its modulation by immunosuppressant drugs and viral transactivating proteins will guide future therapies of lung inflammation. ..