Neeraja Kambham

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Postinfectious glomerulonephritis
    Neeraja Kambham
    Department of Pathology, Stanford University Medical Center, Stanford, CA, USA
    Adv Anat Pathol 19:338-47. 2012
  2. doi request reprint Crescentic Glomerulonephritis: an update on Pauci-immune and Anti-GBM diseases
    Neeraja Kambham
    Department of Pathology, Stanford University Medical Center, Stanford, CA
    Adv Anat Pathol 19:111-24. 2012
  3. ncbi request reprint A novel, semiquantitative, clinically correlated calcineurin inhibitor toxicity score for renal allograft biopsies
    Neeraja Kambham
    Department of Pathology, Stanford, CA 94305 5324, USA
    Clin J Am Soc Nephrol 2:135-42. 2007
  4. ncbi request reprint Utility of syndecan-1 (CD138) expression in the diagnosis of undifferentiated malignant neoplasms: a tissue microarray study of 1,754 cases
    Neeraja Kambham
    Department of Pathology, Stanford University School of Medicine, CA 94305, USA
    Appl Immunohistochem Mol Morphol 13:304-10. 2005
  5. pmc Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions
    Rong Chen
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS Comput Biol 6:. 2010
  6. pmc Expression of complement components differs between kidney allografts from living and deceased donors
    Maarten Naesens
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Am Soc Nephrol 20:1839-51. 2009
  7. pmc Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures
    Li Li
    Department of Pediatrics, Blood and Marrow Transplantation Division, Stanford University, 300 Pasteur Drive, Stanford, CA 94304, USA
    Proc Natl Acad Sci U S A 106:4148-53. 2009
  8. pmc Compartmental localization and clinical relevance of MICA antibodies after renal transplantation
    Li Li
    Department of Pediatrics, Stanford University, Stanford, CA, USA 2 Department of Pathology, Stanford University, Stanford, CA 94304, USA
    Transplantation 89:312-9. 2010
  9. doi request reprint Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation
    Lauren Weintraub
    Department of Pediatrics, Stanford University, Stanford, CA, USA
    Pediatr Transplant 12:541-9. 2008
  10. doi request reprint Characterization of intra-graft B cells during renal allograft rejection
    Valeriya Zarkhin
    Department of Pediatrics, Stanford University Medical Center, Stanford, California, USA
    Kidney Int 74:664-73. 2008

Collaborators

Detail Information

Publications37

  1. doi request reprint Postinfectious glomerulonephritis
    Neeraja Kambham
    Department of Pathology, Stanford University Medical Center, Stanford, CA, USA
    Adv Anat Pathol 19:338-47. 2012
    ..The wide spectrum of morphologic changes seen in PIGN poses a diagnostic challenge, especially if adequate clinical and serological data are lacking...
  2. doi request reprint Crescentic Glomerulonephritis: an update on Pauci-immune and Anti-GBM diseases
    Neeraja Kambham
    Department of Pathology, Stanford University Medical Center, Stanford, CA
    Adv Anat Pathol 19:111-24. 2012
    ..Even in light of advances in understanding of pathophysiology and serologic testing, renal biopsy remains the mainstay of diagnosis of crescentic GN...
  3. ncbi request reprint A novel, semiquantitative, clinically correlated calcineurin inhibitor toxicity score for renal allograft biopsies
    Neeraja Kambham
    Department of Pathology, Stanford, CA 94305 5324, USA
    Clin J Am Soc Nephrol 2:135-42. 2007
    ..021) and 24 mo (P = 0.03) calculated creatinine clearance. Arteriolar medial hyalinosis seems to be the most important factor contributing to the clinical impact of the CNIT score...
  4. ncbi request reprint Utility of syndecan-1 (CD138) expression in the diagnosis of undifferentiated malignant neoplasms: a tissue microarray study of 1,754 cases
    Neeraja Kambham
    Department of Pathology, Stanford University School of Medicine, CA 94305, USA
    Appl Immunohistochem Mol Morphol 13:304-10. 2005
    ..Furthermore, the two commercially available monoclonal CD138 antibodies tested in this study showed significant differences in their immunoreactivity in different tumor types...
  5. pmc Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions
    Rong Chen
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS Comput Biol 6:. 2010
    ....
  6. pmc Expression of complement components differs between kidney allografts from living and deceased donors
    Maarten Naesens
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Am Soc Nephrol 20:1839-51. 2009
    ..In addition, complement gene expression at the time of implantation was associated with both early and late graft function. These data suggest that complement-modulating therapy may improve graft outcomes in renal transplantation...
  7. pmc Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures
    Li Li
    Department of Pediatrics, Blood and Marrow Transplantation Division, Stanford University, 300 Pasteur Drive, Stanford, CA 94304, USA
    Proc Natl Acad Sci U S A 106:4148-53. 2009
    ..Correlation of the most significant non-HLA antibody responses with transplant health and dysfunction are currently underway...
  8. pmc Compartmental localization and clinical relevance of MICA antibodies after renal transplantation
    Li Li
    Department of Pediatrics, Stanford University, Stanford, CA, USA 2 Department of Pathology, Stanford University, Stanford, CA 94304, USA
    Transplantation 89:312-9. 2010
    ..Antibodies (Ab) responses to major and minor human leukocyte antigen loci may impact graft survival after organ transplantation...
  9. doi request reprint Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation
    Lauren Weintraub
    Department of Pediatrics, Stanford University, Stanford, CA, USA
    Pediatr Transplant 12:541-9. 2008
    ..Worsening graft function and graft loss may be minimized by selecting patients with high CNIT scores and low biopsy chronicity and excluding patients with prior AR history...
  10. doi request reprint Characterization of intra-graft B cells during renal allograft rejection
    Valeriya Zarkhin
    Department of Pediatrics, Stanford University Medical Center, Stanford, California, USA
    Kidney Int 74:664-73. 2008
    ..These studies suggest that detailed analysis of interstitial cellular infiltrates may allow better use of B-cell lineage specific treatments to improve graft outcomes...
  11. pmc Host-derived interleukin-18 differentially impacts regulatory and conventional T cell expansion during acute graft-versus-host disease
    Robert Zeiser
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Biol Blood Marrow Transplant 13:1427-38. 2007
    ..We conclude that host-derived IL-18 is a major factor for IFN-gamma production that may have a protective effect on CD4(+)-mediated aGVHD, but is nonessential for Treg expansion in an allogeneic environment...
  12. pmc CD8+CD44(hi) but not CD4+CD44(hi) memory T cells mediate potent graft antilymphoma activity without GVHD
    Suparna Dutt
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Blood 117:3230-9. 2011
    ..In conclusion, the memory CD8(+) T-cell subset separated graft antilymphoma activity from GVHD more effectively than naive T cells, memory CD4(+) T cells, or memory total T cells...
  13. doi request reprint Rituximab treatment for recurrence of nephrotic syndrome in a pediatric patient after renal transplantation for congenital nephrotic syndrome of Finnish type
    Abanti Chaudhuri
    Department of Pediatrics, Stanford University, Stanford, CA 94305, USA
    Pediatr Transplant 16:E183-7. 2012
    ..The child remains in remission 5 yr following treatment. Our experience suggests that activated B cells may play a pivotal role in the recurrence of nephrosis after renal transplantation in children with CNS...
  14. doi request reprint Maturation of dose-corrected tacrolimus predose trough levels in pediatric kidney allograft recipients
    Maarten Naesens
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
    Transplantation 85:1139-45. 2008
    ....
  15. pmc Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells
    Robert Zeiser
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Blood 111:453-62. 2008
    ....
  16. ncbi request reprint Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling
    Minnie Sarwal
    Department of Pediatrics, Stanford University, Stanford, Calif, USA
    N Engl J Med 349:125-38. 2003
    ..We hypothesized that previously unrecognized molecular heterogeneity might underlie some of the variability in the clinical course of acute renal allograft rejection and in its response to treatment...
  17. pmc Beta-galactosylceramide alters invariant natural killer T cell function and is effective treatment for lupus
    Sufi R Morshed
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Clin Immunol 132:321-33. 2009
    ..In conclusion, beta-galactosylceramide, a glycolipid that reduces the cytokine secretion induced by a potent NKT cell agonist ameliorates lupus in NZB/W mice...
  18. pmc Toll-like receptor 4 contributes to small intestine allograft rejection
    Sheri M Krams
    Department of Surgery Division of Transplantation, Stanford University School of Medicine, Stanford, CA, USA
    Transplantation 90:1272-7. 2010
    ..In this study, we examine the participation of TLR4 in acute allograft rejection in an orthotopic mouse model of SIT...
  19. doi request reprint Renal pathology in hematopoietic cell transplantation recipients
    Megan L Troxell
    Department of Pathology, Oregon Health and Science University, L471, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    Mod Pathol 21:396-406. 2008
    ....
  20. pmc Gene expression in the normal adult human kidney assessed by complementary DNA microarray
    John P T Higgins
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Mol Biol Cell 15:649-56. 2004
    ..The distinctive patterns of gene expression in discrete portions of the kidney may serve as a resource for further understanding of renal physiology and the molecular and cellular organization of the nephron...
  21. ncbi request reprint Comparison of C4d immunostaining methods in renal allograft biopsies
    Megan L Troxell
    Oregon Health and Science University, Department of Pathology, L471, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    Clin J Am Soc Nephrol 1:583-91. 2006
    ..Direct comparison demonstrates that IHC staining of formalin-fixed, paraffin-embedded tissue with anti-C4d polyclonal antibody has acceptable sensitivity and specificity, as compared with IF staining of frozen tissue with the Quidel mAb...
  22. pmc H-Y antibody development associates with acute rejection in female patients with male kidney transplants
    Jane C Tan
    Department of Medicine, Stanford University Medical Center, Stanford, CA, USA
    Transplantation 86:75-81. 2008
    ..We hypothesized that women with male kidney transplants would develop antibodies against H-Y, the mHA encoded on the Y-chromosome, in association with graft rejection...
  23. doi request reprint Decreases in circulating CD4+CD25hiFOXP3+ cells and increases in intragraft FOXP3+ cells accompany allograft rejection in pediatric liver allograft recipients
    Fabien Stenard
    Division of Transplantation, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305 5492, USA
    Pediatr Transplant 13:70-80. 2009
    ..Moreover, monitoring peripheral CD4(+)CD25(hi)FOXP3(+) Treg cell levels may be useful in improving the post-transplant management of pediatric liver allograft recipients...
  24. ncbi request reprint Gastrointestinal leukocytoclastic vasculitis: an adverse effect of sirolimus
    Suja Nagarajan
    Department of Pediatric Nephrology, Stanford University, Stanford, CA 94305, USA
    Pediatr Transplant 9:97-100. 2005
    ..In light of this report, drug-induced leukocytoclastic vasculitis caused by SRL should be considered in the differential diagnosis of chronic abdominal pain in a patient with organ transplantation...
  25. ncbi request reprint Evaluation of C4d staining in liver and small intestine allografts
    Megan L Troxell
    Department of Pathology, Stanford University Medical Center, Stanford, Calif, USA
    Arch Pathol Lab Med 130:1489-96. 2006
    ..C4d deposition in allograft biopsy specimens occurs at sites of antibody-mediated complement activation and has become one of the histopathologic criteria for diagnosis of humoral rejection in the kidney and the heart...
  26. pmc The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation
    Vu H Nguyen
    Department of Medicine, Stanford University, CA, USA
    Blood 111:945-53. 2008
    ..These findings provide new insights into the role of Tregs in affording protection to lymphoid stromal elements important for T-cell immunity...
  27. ncbi request reprint Liver allografts are toleragenic in rats conditioned with posttransplant total lymphoid irradiation
    Kazuhito Nagasaki
    Department of Surgery, Division of Transplantation, Stanford University School of Medicine, Stanford, CA, USA
    Transplantation 84:619-28. 2007
    ..Posttransplant total lymphoid irradiation (TLI) treatment has been applied to tolerance induction protocols in heart and kidney transplantation models...
  28. doi request reprint Fibronectin glomerulopathy: an unusual cause of adult-onset nephrotic syndrome
    Mridula Nadamuni
    Department of Pathology, Stanford University, Stanford, CA
    Am J Kidney Dis 60:839-42. 2012
    ..This mutation affects Hep-III, one of the heparin-binding domains of fibronectin, and results in functional abnormalities...
  29. pmc The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth
    Kevin L Bennewith
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    Cancer Res 69:775-84. 2009
    ....
  30. doi request reprint Caspase-4 may play a role in loss of proximal tubules and renal injury in nephropathic cystinosis
    Poonam Sansanwal
    Department of Pediatrics, Stanford University, G306, 300 Pasteur Drive, Stanford, CA 94304, USA
    Pediatr Nephrol 25:105-9. 2010
    ..Further work is needed to elucidate if this injury mechanism may be causative for the progression of renal functional decline in nephropathic cystinosis...
  31. ncbi request reprint Multinucleated epithelial giant cells in colorectal polyps: a potential mimic of viropathic and/or dysplastic changes
    Neeraja Kambham
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Am J Surg Pathol 29:912-9. 2005
    ..These changes appear to represent a nonspecific, possibly degenerative response to inflammation and injury, and should be distinguished from dysplasia...
  32. doi request reprint A study of interobserver reproducibility of morphologic lesions of focal segmental glomerulosclerosis
    Shane M Meehan
    Department of Pathology, University of Chicago, 5841 South Maryland Ave, Chicago, IL 60637, USA
    Virchows Arch 462:229-37. 2013
    ..The morphologic forms of FSGS defined by the Columbia system are reproducible between observers and have a low probability of confusion between forms. Individual glomeruli may have overlapping features of more than one form of FSGS...
  33. doi request reprint A 30-month-old child with acute renal failure due to primary renal cytotoxic T-cell lymphoma
    Srikanth Paladugu
    Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA
    Am J Surg Pathol 34:1066-70. 2010
    ..We review the literature on primary renal lymphoma with an emphasis on T-lineage lymphomas and those that occur in children...
  34. pmc Preemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity
    Robert Zeiser
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Blood 110:4588-98. 2007
    ....
  35. ncbi request reprint Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis
    Nadja Dornhöfer
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    Cancer Res 66:5816-27. 2006
    ..Together, these studies implicate CTGF as a new target in pancreatic cancer and suggest that inhibition of CTGF with a human monoclonal antibody may control primary and metastatic tumor growth...
  36. ncbi request reprint Cytomegalovirus infection in steroid-refractory ulcerative colitis: a case-control study
    Neeraja Kambham
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Am J Surg Pathol 28:365-73. 2004
    ....
  37. ncbi request reprint A randomized, placebo-controlled trial of IGF-1 for delayed graft function: a human model to study postischemic ARF
    Michelle A Hladunewich
    Division of Nephrology, Department of Medicine, Stanford University, Stanford, California, USA
    Kidney Int 64:593-602. 2003
    ..Such patients often had multiple organ failure, recurrent renal injury, and a delay of several days before commencing treatment...