Laura Johnston

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Sirolimus and mycophenolate mofetil as GVHD prophylaxis in myeloablative, matched-related donor hematopoietic cell transplantation
    L Johnston
    Department of Medicine, Stanford University, Stanford, CA, USA
    Bone Marrow Transplant 47:581-8. 2012
  2. doi request reprint Acute graft-versus-host disease: differing risk with differing graft sources and conditioning intensity
    Laura Johnston
    Division of Blood and Marrow Transplantation, Stanford University, 300 Pasteur Drive, H3249, Stanford, CA 94305, USA
    Best Pract Res Clin Haematol 21:177-92. 2008
  3. ncbi request reprint Autologous hematopoietic cell transplantation in non-Hodgkin's lymphoma
    L J Johnston
    Division of Bone Marrow Transplantation, Stanford University Medical Center, California, USA
    Hematol Oncol Clin North Am 13:889-918. 1999
  4. ncbi request reprint Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease
    Laura J Johnston
    Stanford University, Stanford, California 94305, USA
    Biol Blood Marrow Transplant 11:47-55. 2005
  5. ncbi request reprint Toxicity of high-dose sequential chemotherapy and purged autologous hematopoietic cell transplantation precludes its use in refractory/recurrent non-Hodgkin's lymphoma
    L J Johnston
    Division of Bone Marrow Transplantation, Stanford University, California 94305, USA
    Biol Blood Marrow Transplant 6:555-62. 2000
  6. pmc Phase I/II trial of GN-BVC, a gemcitabine and vinorelbine-containing conditioning regimen for autologous hematopoietic cell transplantation in recurrent and refractory hodgkin lymphoma
    Sally Arai
    Department of Medicine, Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, California 94305, USA
    Biol Blood Marrow Transplant 16:1145-54. 2010
  7. doi request reprint Early CMV viremia is associated with impaired viral control following nonmyeloablative hematopoietic cell transplantation with a total lymphoid irradiation and antithymocyte globulin preparative regimen
    Joanna M Schaenman
    Division of Infectious Diseases, Stanford University Medical Center, Stanford, California 94305 5623, USA
    Biol Blood Marrow Transplant 17:693-702. 2011
  8. ncbi request reprint High-dose carmustine, etoposide, and cyclophosphamide followed by allogeneic hematopoietic cell transplantation for non-Hodgkin lymphoma
    Lisa Y Law
    Division of Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, California 94305, USA
    Biol Blood Marrow Transplant 12:703-11. 2006
  9. pmc TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors
    Holbrook E Kohrt
    Department of Medicine, Stanford University School of Medicine, CA 94305, USA
    Blood 114:1099-109. 2009
  10. ncbi request reprint Engraftment and survival following reduced-intensity allogeneic peripheral blood hematopoietic cell transplantation is affected by CD8+ T-cell dose
    Thai M Cao
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University Schol of Medicine, 300 Pasteur Dr, H3249, MC 5623, Stanford, CA 94305 5623, USA
    Blood 105:2300-6. 2005

Collaborators

Detail Information

Publications14

  1. pmc Sirolimus and mycophenolate mofetil as GVHD prophylaxis in myeloablative, matched-related donor hematopoietic cell transplantation
    L Johnston
    Department of Medicine, Stanford University, Stanford, CA, USA
    Bone Marrow Transplant 47:581-8. 2012
    ..The severe toxicities in the patients receiving the BU-containing preparative regimens limited the continued use of sirolimus and MMF for the prevention of AGVHD...
  2. doi request reprint Acute graft-versus-host disease: differing risk with differing graft sources and conditioning intensity
    Laura Johnston
    Division of Blood and Marrow Transplantation, Stanford University, 300 Pasteur Drive, H3249, Stanford, CA 94305, USA
    Best Pract Res Clin Haematol 21:177-92. 2008
    ..More formal comparisons of the different graft sources as well as preparative regimen intensities will be required to determine a more accurate picture of the differences between these transplantation alternatives...
  3. ncbi request reprint Autologous hematopoietic cell transplantation in non-Hodgkin's lymphoma
    L J Johnston
    Division of Bone Marrow Transplantation, Stanford University Medical Center, California, USA
    Hematol Oncol Clin North Am 13:889-918. 1999
    ..A large number of NHL patients succumb to their disease, so it is hoped that alternate therapies, such as cytokines, monoclonal antibodies, and vaccines, may improve the results of HDT...
  4. ncbi request reprint Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease
    Laura J Johnston
    Stanford University, Stanford, California 94305, USA
    Biol Blood Marrow Transplant 11:47-55. 2005
    ..Given the significant toxicities described, investigation of altered administration of rapamycin and calcineurin inhibitors should be pursued in future cGVHD trials...
  5. ncbi request reprint Toxicity of high-dose sequential chemotherapy and purged autologous hematopoietic cell transplantation precludes its use in refractory/recurrent non-Hodgkin's lymphoma
    L J Johnston
    Division of Bone Marrow Transplantation, Stanford University, California 94305, USA
    Biol Blood Marrow Transplant 6:555-62. 2000
    ..We conclude that HDSC/AHCT in refractory/recurrent NHL is associated with considerable acute and chronic toxicities. Given the toxicity profile, efficacy data were not sufficiently promising to warrant further study...
  6. pmc Phase I/II trial of GN-BVC, a gemcitabine and vinorelbine-containing conditioning regimen for autologous hematopoietic cell transplantation in recurrent and refractory hodgkin lymphoma
    Sally Arai
    Department of Medicine, Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, California 94305, USA
    Biol Blood Marrow Transplant 16:1145-54. 2010
    ..This new transplant regimen for HL resulted in decreased BCNU toxicity with encouraging FFP and OS. A prospective, risk-modeled comparison of this new combination with other conditioning regimens is warranted...
  7. doi request reprint Early CMV viremia is associated with impaired viral control following nonmyeloablative hematopoietic cell transplantation with a total lymphoid irradiation and antithymocyte globulin preparative regimen
    Joanna M Schaenman
    Division of Infectious Diseases, Stanford University Medical Center, Stanford, California 94305 5623, USA
    Biol Blood Marrow Transplant 17:693-702. 2011
    ..These observations demonstrate the dynamic nature of immunity in relation to CMV antigen exposure in the complex environment resulting from NMA conditions where both donor and residual recipient immune response affect viral control...
  8. ncbi request reprint High-dose carmustine, etoposide, and cyclophosphamide followed by allogeneic hematopoietic cell transplantation for non-Hodgkin lymphoma
    Lisa Y Law
    Division of Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, California 94305, USA
    Biol Blood Marrow Transplant 12:703-11. 2006
    ..Patients who had required >3 previous chemotherapy regimens before HCT had an increased probability of relapse. CBV is an effective preparative regimen for patients with aggressive NHL who undergo allogeneic HCT...
  9. pmc TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors
    Holbrook E Kohrt
    Department of Medicine, Stanford University School of Medicine, CA 94305, USA
    Blood 114:1099-109. 2009
    ..Active trial registration currently at clinicaltrials.gov under IDs of NCT00185640 and NCT00186615...
  10. ncbi request reprint Engraftment and survival following reduced-intensity allogeneic peripheral blood hematopoietic cell transplantation is affected by CD8+ T-cell dose
    Thai M Cao
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University Schol of Medicine, 300 Pasteur Dr, H3249, MC 5623, Stanford, CA 94305 5623, USA
    Blood 105:2300-6. 2005
    ..003; RR = 0.2, 95% CI = 0.1-0.6) was associated with improved freedom from progression. Infusion of low G-PBMC CD8+ T-cell dose for reduced-intensity allografting may adversely affect T-cell engraftment and survival outcome...
  11. ncbi request reprint Protective conditioning for acute graft-versus-host disease
    Robert Lowsky
    Department of Medicine, Stanford University School of Medicine, Stanford, Calif, USA
    N Engl J Med 353:1321-31. 2005
    ..Conditioning with total lymphoid irradiation plus antithymocyte serum protects mice against acute graft-versus-host disease (GVHD) after hematopoietic-cell transplantation. We tested this strategy in humans...
  12. ncbi request reprint CD34, CD4, and CD8 cell doses do not influence engraftment, graft-versus-host disease, or survival following myeloablative human leukocyte antigen-identical peripheral blood allografting for hematologic malignancies
    Thai M Cao
    Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5623, USA
    Exp Hematol 33:279-85. 2005
    ..G-PBMC cell contents were analyzed for influence on outcomes...
  13. ncbi request reprint Rituximab as adjuvant to high-dose therapy and autologous hematopoietic cell transplantation for aggressive non-Hodgkin lymphoma
    Steven M Horwitz
    Division of Oncology, Stanford University Medical Center, Ste 202, 1000 Welch Rd, Palo Alto, CA 94304, USA
    Blood 103:777-83. 2004
    ..Rituximab after HDT and HCT is feasible, and these phase 2 data support the current US Intergroup phase 3 trial in recurrent/refractory diffuse large cell lymphoma...
  14. ncbi request reprint Comparison of chronic graft-versus-host disease after transplantation of peripheral blood stem cells versus bone marrow in allogeneic recipients: long-term follow-up of a randomized trial
    Mary E D Flowers
    Division of Clinical Research, Fred Hutchinson Cancer Research Center and Department of Medicine, University of Washington, Seattle, WA 98109, USA
    Blood 100:415-9. 2002
    ..Assessment of the overall benefits of PBSCT compared to BMT will require continued long-term follow up of morbidity associated with chronic GVHD...