S S Jeffrey

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Cancer biomarker profiling with microRNAs
    Stefanie S Jeffrey
    Nat Biotechnol 26:400-1. 2008
  2. pmc Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines
    Ashley A Powell
    Department of Surgery, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 7:e33788. 2012
  3. pmc A pharmacogenomic method for individualized prediction of drug sensitivity
    Adam L Cohen
    Division of Internal Medicine, Department of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA
    Mol Syst Biol 7:513. 2011
  4. pmc TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
    Anita Langerød
    Department of Genetics, Institute for Cancer Research, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway N 0310
    Breast Cancer Res 9:R30. 2007
  5. pmc RNA extraction from ten year old formalin-fixed paraffin-embedded breast cancer samples: a comparison of column purification and magnetic bead-based technologies
    Alfredo Ribeiro-Silva
    Department of Surgery, Stanford University School of Medicine, MSLS Bldg Room P214 1201 Welch Road, Stanford, CA 94305 5494, USA
    BMC Mol Biol 8:118. 2007
  6. pmc A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue
    Shanaz H Dairkee
    California Pacific Medical Center, San Francisco, CA 94115 1932, USA
    BMC Genomics 5:47. 2004
  7. pmc Discovery and validation of breast cancer subtypes
    Amy V Kapp
    Department of Statistics, Stanford University, Stanford, CA, USA
    BMC Genomics 7:231. 2006
  8. pmc New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients
    Holbrook E Kohrt
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA
    BMC Cancer 8:66. 2008
  9. ncbi request reprint Genomics-based prognosis and therapeutic prediction in breast cancer
    Stefanie S Jeffrey
    Department of Surgery, Stanford University School of Medicine, Stanford, California, 94305 5494, USA
    J Natl Compr Canc Netw 3:291-300. 2005
  10. ncbi request reprint Expression array technology in the diagnosis and treatment of breast cancer
    Stefanie S Jeffrey
    Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA
    Mol Interv 2:101-9. 2002

Detail Information

Publications40

  1. doi request reprint Cancer biomarker profiling with microRNAs
    Stefanie S Jeffrey
    Nat Biotechnol 26:400-1. 2008
  2. pmc Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines
    Ashley A Powell
    Department of Surgery, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 7:e33788. 2012
    ..Here we demonstrate feasibility of performing high dimensional single CTC profiling, providing early insight into CTC heterogeneity and allowing comparisons to breast cancer cell lines widely used for drug discovery...
  3. pmc A pharmacogenomic method for individualized prediction of drug sensitivity
    Adam L Cohen
    Division of Internal Medicine, Department of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA
    Mol Syst Biol 7:513. 2011
    ..MATCH uses genomic analysis with in vitro testing of patient tumors to select optimal drug regimens before clinical trial initiation...
  4. pmc TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
    Anita Langerød
    Department of Genetics, Institute for Cancer Research, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway N 0310
    Breast Cancer Res 9:R30. 2007
    ....
  5. pmc RNA extraction from ten year old formalin-fixed paraffin-embedded breast cancer samples: a comparison of column purification and magnetic bead-based technologies
    Alfredo Ribeiro-Silva
    Department of Surgery, Stanford University School of Medicine, MSLS Bldg Room P214 1201 Welch Road, Stanford, CA 94305 5494, USA
    BMC Mol Biol 8:118. 2007
    ....
  6. pmc A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue
    Shanaz H Dairkee
    California Pacific Medical Center, San Francisco, CA 94115 1932, USA
    BMC Genomics 5:47. 2004
    ..To identify the spectrum of malignant attributes maintained outside the host environment, we have compared global gene expression in primary breast tumors and matched short-term epithelial cultures...
  7. pmc Discovery and validation of breast cancer subtypes
    Amy V Kapp
    Department of Statistics, Stanford University, Stanford, CA, USA
    BMC Genomics 7:231. 2006
    ..The most recent study presented evidence for the existence of five different subtypes: normal breast-like, basal, luminal A, luminal B, and ERBB2+...
  8. pmc New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients
    Holbrook E Kohrt
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA
    BMC Cancer 8:66. 2008
    ..Our goal was to develop new models to quantify the risk of NSLN metastasis in SLN-positive patients and to compare predictive capabilities to another widely used model...
  9. ncbi request reprint Genomics-based prognosis and therapeutic prediction in breast cancer
    Stefanie S Jeffrey
    Department of Surgery, Stanford University School of Medicine, Stanford, California, 94305 5494, USA
    J Natl Compr Canc Netw 3:291-300. 2005
    ..We believe that the characterization and discernment of different systems among breast cancers is crucial for understanding drug sensitivity and resistance mechanisms and for guiding therapy...
  10. ncbi request reprint Expression array technology in the diagnosis and treatment of breast cancer
    Stefanie S Jeffrey
    Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA
    Mol Interv 2:101-9. 2002
    ..Thus, microarray analysis may translate basic research data into more confident diagnoses, specifically designed treatment regimens geared to each patient's needs, and better clinical prognoses...
  11. pmc The diagnosis and management of pre-invasive breast disease: promise of new technologies in understanding pre-invasive breast lesions
    Stefanie S Jeffrey
    Stanford University School of Medicine, Stanford, California, USA
    Breast Cancer Res 5:320-8. 2003
    ..It is expected that molecular technologies will identify breast tissue at risk for the development of unfavorable subtypes of invasive breast cancer and reveal strategies for targeted chemoprevention or eradication...
  12. ncbi request reprint Controversies in sentinel lymph node biopsy for breast cancer
    S S Jeffrey
    Division of Surgical Oncology, Stanford University School of Medicine, California, USA
    Cancer Biother Radiopharm 15:223-33. 2000
    ..This paper will address some of the controversial areas of sentinel lymph node biopsy and offer an option for physicians who want to develop a sentinel lymph node program in their hospital...
  13. ncbi request reprint Radiofrequency ablation of breast cancer: first report of an emerging technology
    S S Jeffrey
    Department of Surgery, Stanford University School of Medicine, Calif, USA
    Arch Surg 134:1064-8. 1999
    ..Radiofrequency (RF) energy applied to breast cancers will result in cancer cell death...
  14. ncbi request reprint Molecular portraits of human breast tumours
    C M Perou
    Department of Genetics, Stanford University School of Medicine, California 94305, USA
    Nature 406:747-52. 2000
    ..The tumours could be classified into subtypes distinguished by pervasive differences in their gene expression patterns...
  15. ncbi request reprint Freehand iMRI-guided large-gauge core needle biopsy: a new minimally invasive technique for diagnosis of enhancing breast lesions
    B L Daniel
    Department of Radiology, Stanford University, Stanford, California 94305, USA
    J Magn Reson Imaging 13:896-902. 2001
    ..J. Magn. Reson. Imaging 2001;13:896-902...
  16. ncbi request reprint Predictors of reexcision findings and recurrence after breast conservation
    Melanie C Smitt
    Department of Radiation Oncology, Stanford University, Stanford, CA, USA
    Int J Radiat Oncol Biol Phys 57:979-85. 2003
    ..To identify predictors of reexcision findings and local recurrence in the setting of breast-conserving therapy with radiation...
  17. ncbi request reprint Cell trapping in activated micropores for functional analysis
    AmirAli H Talasaz
    Electr Eng Dept, Stanford Univ, CA 94305, USA
    Conf Proc IEEE Eng Med Biol Soc 1:1838-41. 2006
    ..In the process, single cells are precisely positioned and captured in activated micropores. To show the performance of the proposed device, cultured yeast cells and human epithelial circulating tumor cells are successfully captured...
  18. ncbi request reprint The evolution of accelerated, partial breast irradiation as a potential treatment option for women with newly diagnosed breast cancer considering breast conservation
    Frederick M Dirbas
    Division of General Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA
    Cancer Biother Radiopharm 19:673-705. 2004
    ....
  19. pmc Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
    Jonathan R Pollack
    Departments of Pathology, Genetics, Surgery, Health Research and Policy, and Biochemistry, and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 99:12963-8. 2002
    ..These findings provide evidence that widespread DNA copy number alteration can lead directly to global deregulation of gene expression, which may contribute to the development or progression of cancer...
  20. doi request reprint Focal amplification and oncogene dependency of GAB2 in breast cancer
    M Bocanegra
    Department of Pathology, Stanford University, Stanford, CA 94305 5176, USA
    Oncogene 29:774-9. 2010
    ..Our studies implicate focal amplification of GAB2 in breast carcinogenesis, and underscore an oncogenic role of scaffolding adapter proteins, and a potential new point of therapeutic intervention...
  21. pmc Different gene expression patterns in invasive lobular and ductal carcinomas of the breast
    Hongjuan Zhao
    Department of Surgery, Stanford University School of Medicine, Stanford, California 94305, USA
    Mol Biol Cell 15:2523-36. 2004
    ..The remaining ILCs closely resemble IDCs in their transcription patterns. Further studies are needed to explore the differences between ILC molecular subtypes and to determine whether they require different therapeutic strategies...
  22. ncbi request reprint Disease-specific genomic analysis: identifying the signature of pathologic biology
    Monica Nicolau
    Department of Surgery, Stanford University School of Medicine, Stanford University, Stanford, CA, USA
    Bioinformatics 23:957-65. 2007
    ..Genomic high-throughput technology generates massive data, providing opportunities to understand countless facets of the functioning genome. It also raises profound issues in identifying data relevant to the biology being studied...
  23. ncbi request reprint Transcriptomic signatures in breast cancer
    Jianjiang Fu
    Stanford University Medical Center, Stanford, CA 94305 5494, USA
    Mol Biosyst 3:466-72. 2007
    ..Newer bioinformatic approaches are being developed to assist with the analysis of this important data...
  24. ncbi request reprint Breast cancer: variables affecting sentinel lymph node visualization at preoperative lymphoscintigraphy
    R L Birdwell
    Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr, H 1307, Stanford, CA 94305 5105, USA
    Radiology 220:47-53. 2001
    ....
  25. ncbi request reprint Management of breast cancer after Hodgkin's disease
    S L Wolden
    Departments of Radiation Oncology, Medicine, and Surgery, Stanford University Medical Center, Stanford, CA, USA
    J Clin Oncol 18:765-72. 2000
    ..To evaluate the incidence, detection, pathology, management, and prognosis of breast cancer occurring after Hodgkin's disease...
  26. ncbi request reprint Rates of reexcision for breast cancer after magnetic resonance imaging-guided bracket wire localization
    Anne Marie Wallace
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA
    J Am Coll Surg 200:527-37. 2005
    ..We performed this study to determine rates of close or transected cancer margins after magnetic resonance imaging-guided bracket wire localization for nonpalpable breast lesions...
  27. pmc Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype
    K Ameri
    Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305 5494, USA
    Br J Cancer 102:561-9. 2010
    ..The aim of this study was to examine the as yet unknown relationship between hypoxia and CTCs...
  28. doi request reprint Estrogen receptor-negative invasive breast cancer: imaging features of tumors with and without human epidermal growth factor receptor type 2 overexpression
    Yingbing Wang
    Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305 5494, USA
    Radiology 246:367-75. 2008
    ....
  29. ncbi request reprint Magnetic resonance imaging of suspicious breast masses seen on one mammographic view
    Regina S Offodile
    Department of Surgery, Stanford University School of Medicine, CA, USA
    Breast J 10:416-22. 2004
    ..Breast MRI has the advantage of imaging the entire breast and is particularly useful for these lesions. In this series, MRI prevented delay in breast cancer diagnosis...
  30. ncbi request reprint Locally advanced breast cancer: is surgery necessary?
    A M Favret
    Department of Medicine, Stanford University Medical Center, Stanford, California 94305 5115, USA
    Breast J 7:131-7. 2001
    ..5%. These data indicate that the routine inclusion of breast surgery in a combined modality treatment program for LABC does not appear necessary for the majority of patients who experience a response to induction chemotherapy...
  31. ncbi request reprint MRI-guided needle localization of suspicious breast lesions: results of a freehand technique
    M A A J van den Bosch
    Department of Radiology, Stanford University Medical Center, Stanford, CA 94305 5105, USA
    Eur Radiol 16:1811-7. 2006
    ..7%) lesions were missed by surgical biopsy. MRI-guided freehand needle localization is accurate and allows localization of lesions anterior in the breast, the axillary region, and near the chest wall...
  32. pmc Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device
    AmirAli H Talasaz
    Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 106:3970-5. 2009
    ..In contrast, we could not find any circulating epithelial cells in samples from 5 healthy donors. The isolated CEpCs are all stored individually for further molecular analysis...
  33. ncbi request reprint Lysyl oxidase is essential for hypoxia-induced metastasis
    Janine T Erler
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 440:1222-6. 2006
    ..Furthermore, LOX may be required to create a niche permissive for metastatic growth. Our findings indicate that LOX is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases...
  34. ncbi request reprint A streamlined platform for high-content functional proteomics of primary human specimens
    Nadim Jessani
    The Skaggs Institute for Chemical Biology and Department of Cell Biology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, California 92037, USA
    Nat Methods 2:691-7. 2005
    ....
  35. doi request reprint DNA copy number alterations and expression of relevant genes in triple-negative breast cancer
    Wonshik Han
    Department of Surgery, Seoul National University College of Medicine, Chongno Gu, Seoul 110 744, Korea
    Genes Chromosomes Cancer 47:490-9. 2008
    ..This article contains Supplementary Material available at http://www.interscience.wiley.com/jpages/1045-2257/suppmat...
  36. ncbi request reprint Distribution of persistent, lipid-soluble chemicals in breast and abdominal adipose tissues: lessons learned from a breast cancer study
    Myrto Petreas
    Hazardous Materials Laboratory, California Department of Toxic Substances Control, Berkeley, CA, USA
    Cancer Epidemiol Biomarkers Prev 13:416-24. 2004
    ....
  37. ncbi request reprint Radiation-induced effects on gene expression: an in vivo study on breast cancer
    Aslaug Helland
    Department of Genetics, Institute for Cancer Research, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    Radiother Oncol 80:230-5. 2006
    ..The purpose of this study was to investigate the molecular basis underlying response to radiotherapy in breast cancer tissue...
  38. ncbi request reprint Adipose levels of dioxins and risk of breast cancer
    Peggy Reynolds
    California Department of Health Services, Environmental Health Investigations Branch, 1515 Clay Street, Suite 1700, Oakland, CA 94612, USA
    Cancer Causes Control 16:525-35. 2005
    ..Our objective was to evaluate the breast cancer risk associated with body burden levels of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs)...
  39. ncbi request reprint MRI features of mucosa-associated lymphoid tissue lymphoma in the breast
    Leandro A Espinosa
    Department of Radiology, University of Michigan, Ann Arbor, MI, USA
    AJR Am J Roentgenol 185:199-202. 2005
  40. ncbi request reprint MR imaging features of infiltrating lobular carcinoma of the breast: histopathologic correlation
    Aliya Qayyum
    Department of Radiology, University of California San Francisco, San Francisco, CA 94143 0628, USA
    AJR Am J Roentgenol 178:1227-32. 2002
    ..Our study aimed to correlate the dynamic contrast-enhanced MR appearance of infiltrating lobular carcinoma of the breast with histopathologic findings...