Morgan Huse

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi Structural biology: alive and skiing
    Morgan Huse
    Laboratory of Synthetic Protein Chemistry, Rockefeller University, New York, NY 10021, USA
    Structure 10:137-8. 2002
  2. ncbi T cells as a self-referential, sensory organ
    Mark M Davis
    Howard Hughes Medical Institute, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
    Annu Rev Immunol 25:681-95. 2007
  3. ncbi Shouts, whispers and the kiss of death: directional secretion in T cells
    Morgan Huse
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Nat Immunol 9:1105-11. 2008
  4. ncbi Photochemical approaches to T-cell activation
    Morgan Huse
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Immunology 130:151-7. 2010
  5. ncbi Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
    Michelle Krogsgaard
    The Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 434:238-43. 2005
  6. ncbi Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist
    Morgan Huse
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Immunity 27:76-88. 2007
  7. ncbi The conformational plasticity of protein kinases
    Morgan Huse
    Department of Biological Sciences, Stanford University, Palo Alto, California 94305, USA
    Cell 109:275-82. 2002

Detail Information

Publications7

  1. ncbi Structural biology: alive and skiing
    Morgan Huse
    Laboratory of Synthetic Protein Chemistry, Rockefeller University, New York, NY 10021, USA
    Structure 10:137-8. 2002
    ..Structural biologists of all shapes and sizes gathered recently in Breckenridge, Colorado to discuss recent developments in the field. If we are to believe what they said, the future of structural biology is very bright...
  2. ncbi T cells as a self-referential, sensory organ
    Mark M Davis
    Howard Hughes Medical Institute, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
    Annu Rev Immunol 25:681-95. 2007
    ..With the multitude of specificities available to most T cells, they can thus be considered as a sensory organ, trained on self-peptide-MHCs and primed to detect nonself...
  3. ncbi Shouts, whispers and the kiss of death: directional secretion in T cells
    Morgan Huse
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Nat Immunol 9:1105-11. 2008
    ..Thus, the mode of secretion seems to be tailored to the intended function of the secreted molecule...
  4. ncbi Photochemical approaches to T-cell activation
    Morgan Huse
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Immunology 130:151-7. 2010
    ..Here, I review these efforts and outline future directions for this exciting area of research...
  5. ncbi Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
    Michelle Krogsgaard
    The Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 434:238-43. 2005
    ....
  6. ncbi Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist
    Morgan Huse
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Immunity 27:76-88. 2007
    ..These results establish the speed and localization of early signaling steps, and have important implications regarding the overall structure of the network...
  7. ncbi The conformational plasticity of protein kinases
    Morgan Huse
    Department of Biological Sciences, Stanford University, Palo Alto, California 94305, USA
    Cell 109:275-82. 2002
    ..By contrast, crystal structures of inactive kinases have revealed a remarkable plasticity in the kinase domain that allows the adoption of distinct conformations in response to interactions with specific regulatory domains or proteins...