Andrew D Huberman

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Decoupling eye-specific segregation from lamination in the lateral geniculate nucleus
    Andrew D Huberman
    Center for Neuroscience, University of California, Davis, California 95616, USA
    J Neurosci 22:9419-29. 2002
  2. ncbi Nob mice wave goodbye to eye-specific segregation
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, California 94305, USA
    Neuron 50:175-7. 2006
  3. pmc Spontaneous retinal activity mediates development of ocular dominance columns and binocular receptive fields in v1
    Andrew D Huberman
    Center for Neuroscience, University of California, Davis, Davis, California 95616, USA
    Neuron 52:247-54. 2006
  4. pmc Mechanisms underlying development of visual maps and receptive fields
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, California 94305, USA
    Annu Rev Neurosci 31:479-509. 2008
  5. ncbi Mechanisms of eye-specific visual circuit development
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Curr Opin Neurobiol 17:73-80. 2007
  6. pmc Early and rapid targeting of eye-specific axonal projections to the dorsal lateral geniculate nucleus in the fetal macaque
    Andrew D Huberman
    Center for Neuroscience, University of California, Davis, Davis, California 95616, USA
    J Neurosci 25:4014-23. 2005
  7. doi Architecture and activity-mediated refinement of axonal projections from a mosaic of genetically identified retinal ganglion cells
    Andrew D Huberman
    Department of Neurobiology, Fairchild Science Building D235, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Neuron 59:425-38. 2008
  8. pmc Genetic identification of an On-Off direction-selective retinal ganglion cell subtype reveals a layer-specific subcortical map of posterior motion
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Neuron 62:327-34. 2009
  9. doi Mammalian DSCAMs: they won't help you find a partner, but they'll guarantee you some personal space
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Neuron 64:441-3. 2009
  10. pmc Transgenic mice reveal unexpected diversity of on-off direction-selective retinal ganglion cell subtypes and brain structures involved in motion processing
    Michal Rivlin-Etzion
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3200, USA
    J Neurosci 31:8760-9. 2011

Collaborators

Detail Information

Publications26

  1. pmc Decoupling eye-specific segregation from lamination in the lateral geniculate nucleus
    Andrew D Huberman
    Center for Neuroscience, University of California, Davis, California 95616, USA
    J Neurosci 22:9419-29. 2002
    ..Clusters of ON-center and OFF-center LGN cells were segregated from one another as in normal animals. However, the organization of ON and OFF sublaminas in the treated animals was disrupted...
  2. ncbi Nob mice wave goodbye to eye-specific segregation
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, California 94305, USA
    Neuron 50:175-7. 2006
    ..These results provide important new insight into the mechanisms that drive eye-specific refinement and stabilization...
  3. pmc Spontaneous retinal activity mediates development of ocular dominance columns and binocular receptive fields in v1
    Andrew D Huberman
    Center for Neuroscience, University of California, Davis, Davis, California 95616, USA
    Neuron 52:247-54. 2006
    ....
  4. pmc Mechanisms underlying development of visual maps and receptive fields
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, California 94305, USA
    Annu Rev Neurosci 31:479-509. 2008
    ..A major goal now is to determine how these molecules cooperate with spontaneous and visually evoked activity to give rise to the circuits underlying precise receptive field tuning and orderly visual maps...
  5. ncbi Mechanisms of eye-specific visual circuit development
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Curr Opin Neurobiol 17:73-80. 2007
    ..Although many outstanding questions remain, the mechanisms that instruct eye-specific circuit development are becoming clear...
  6. pmc Early and rapid targeting of eye-specific axonal projections to the dorsal lateral geniculate nucleus in the fetal macaque
    Andrew D Huberman
    Center for Neuroscience, University of California, Davis, Davis, California 95616, USA
    J Neurosci 25:4014-23. 2005
    ....
  7. doi Architecture and activity-mediated refinement of axonal projections from a mosaic of genetically identified retinal ganglion cells
    Andrew D Huberman
    Department of Neurobiology, Fairchild Science Building D235, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Neuron 59:425-38. 2008
    ..Our findings reveal that in a genetically identified sensory map, spontaneous activity promotes synaptic specificity by segregating axons arising from RGCs of the same subtype...
  8. pmc Genetic identification of an On-Off direction-selective retinal ganglion cell subtype reveals a layer-specific subcortical map of posterior motion
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Neuron 62:327-34. 2009
    ..This suggests that each RGC subtype represents a unique parallel pathway whose synaptic specificity in the retina is recapitulated in central targets...
  9. doi Mammalian DSCAMs: they won't help you find a partner, but they'll guarantee you some personal space
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Neuron 64:441-3. 2009
    ..The results unveil critical features regarding the type and scope of molecular interactions that guide neural circuit assembly in the mammalian CNS...
  10. pmc Transgenic mice reveal unexpected diversity of on-off direction-selective retinal ganglion cell subtypes and brain structures involved in motion processing
    Michal Rivlin-Etzion
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3200, USA
    J Neurosci 31:8760-9. 2011
    ..Our findings reveal unexpected diversity among mouse On-Off DSGC subtypes that uniquely process and convey image motion to the brain...
  11. pmc The Down syndrome critical region regulates retinogeniculate refinement
    Martina Blank
    Department of Psychiatry, Stanford University School of Medicine, Stanford, California, 94305, USA
    J Neurosci 31:5764-76. 2011
    ..Thus, altered developmental refinement of visual circuits that occurs before sensory experience is likely to contribute to visual impairment in individuals with Down syndrome...
  12. pmc Ephrin-As mediate targeting of eye-specific projections to the lateral geniculate nucleus
    Andrew D Huberman
    Center for Neuroscience, 1544 Newton Ct, University of California, Davis, California 95616, USA
    Nat Neurosci 8:1013-21. 2005
    ..These findings represent the first demonstration of eye-specific pathfinding mediated by axon guidance cues and, taken with other reports, indicate that ephrin-As can mediate several mapping functions within individual target structures...
  13. pmc Pathway-specific genetic attenuation of glutamate release alters select features of competition-based visual circuit refinement
    Selina M Koch
    Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA
    Neuron 71:235-42. 2011
    ....
  14. pmc Eye-specific retinogeniculate segregation independent of normal neuronal activity
    Andrew D Huberman
    Center for Neuroscience, School of Medicine, University of California, Davis, CA 95616, USA
    Science 300:994-8. 2003
    ..Thus, certain features of normal neural activity patterns are not required for the formation of eye-specific projections to the DLGN...
  15. ncbi A dedicated circuit links direction-selective retinal ganglion cells to the primary visual cortex
    Alberto Cruz-Martín
    1 Department of Neurosciences, University of California, San Diego, California 92093, USA 2 Neurobiology Section in the Division of Biological Sciences, University of California, San Diego, California 92093, USA
    Nature 507:358-61. 2014
    ..These data provide evidence that direction and orientation selectivity of some V1 neurons may be influenced by the activation of DSGCs. ..
  16. ncbi Dynamics of spontaneous activity in the fetal macaque retina during development of retinogeniculate pathways
    David K Warland
    Department of Ophthalmology and Visual Science, University of California, Davis, California 95616, USA
    J Neurosci 26:5190-7. 2006
    ....
  17. pmc Cadherin-6 mediates axon-target matching in a non-image-forming visual circuit
    Jessica A Osterhout
    Neurosciences Department, School of Medicine, and Neurobiology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA
    Neuron 71:632-9. 2011
    ..These findings provide functional evidence that classical cadherins promote mammalian CNS circuit development by ensuring that axons of specific cell types connect to their appropriate synaptic targets...
  18. ncbi Neurotrophins and visual cortical plasticity
    Andrew D Huberman
    Center for Neuroscience, University of California, Davis, 1544 Newton Court, Davis, CA 95616, USA
    Prog Brain Res 138:39-51. 2002
  19. pmc Emergence of lamina-specific retinal ganglion cell connectivity by axon arbor retraction and synapse elimination
    Ting Wen Cheng
    Center for Neuroscience, University of California, Davis, California 95618, USA
    J Neurosci 30:16376-82. 2010
    ....
  20. pmc The developmental remodeling of eye-specific afferents in the ferret dorsal lateral geniculate nucleus
    Colenso M Speer
    Center for Neuroscience, University of California, Davis, Davis, California 95618, USA
    Anat Rec (Hoboken) 293:1-24. 2010
    ..The emergence of On/Off sublaminae occurs following eye-specific segregation in this species. On the basis of these findings, we constructed a three-dimensional map of eye-specific channels in the developing and mature ferret dLGN...
  21. ncbi The classical complement cascade mediates CNS synapse elimination
    Beth Stevens
    Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Cell 131:1164-78. 2007
    ..These findings support a model in which unwanted synapses are tagged by complement for elimination and suggest that complement-mediated synapse elimination may become aberrantly reactivated in neurodegenerative disease...
  22. ncbi Dendritic and axonal targeting patterns of a genetically-specified class of retinal ganglion cells that participate in image-forming circuits
    Jason W Triplett
    Molecular, Cell and Developmental Biology, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA
    Neural Dev 9:2. 2014
    ..Based on this, we hypothesized that Isl2+ RGCs represent a related subset that share a common function...
  23. pmc Molecular and cellular mechanisms of lamina-specific axon targeting
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Palo Alto, California 94305, USA
    Cold Spring Harb Perspect Biol 2:a001743. 2010
    ..Here, we focus on one of the final steps of synaptic matchmaking: the targeting of synaptic layers and the mutual recognition of axons and dendrites within these layers...
  24. ncbi Target-derived cues instruct synaptic differentiation
    Andrew D Huberman
    Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305, USA
    J Neurosci 26:1063-4. 2006
  25. pmc Neuronal pentraxins mediate synaptic refinement in the developing visual system
    Lisa Bjartmar
    Department of Neurosciences, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Neurosci 26:6269-81. 2006
    ..We speculate that NPs exert their effects through mechanisms that parallel the known role of short pentraxins outside the CNS...
  26. ncbi Crossed and uncrossed retinal projections to the hamster circadian system
    Louise Muscat
    Graduate Program in Neurobiology and Behavior, State University of New York at Stony Brook, Stony Brook, New York 11794, USA
    J Comp Neurol 466:513-24. 2003
    ..This issue is discussed in the context of the melanopsin-containing retinal ganglion cell projections to several nuclei in the circadian visual system...