M A Hlatky

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi Use of medications for secondary prevention after coronary bypass surgery compared with percutaneous coronary intervention
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    J Am Coll Cardiol 61:295-301. 2013
  2. ncbi Epidemiologic and statistical methods for comparative effectiveness research
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Heart Fail Clin 9:29-36. 2013
  3. ncbi Future directions for cardiovascular disease comparative effectiveness research: report of a workshop sponsored by the National Heart, Lung, and Blood Institute
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    J Am Coll Cardiol 60:569-80. 2012
  4. ncbi Characterizing the admixed African ancestry of African Americans
    Fouad Zakharia
    Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Genome Biol 10:R141. 2009
  5. ncbi Economic evaluation in long-term clinical trials
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Stat Med 21:2879-88. 2002
  6. ncbi Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1035-42. 2007
  7. ncbi Cost-effectiveness as an outcome in randomized clinical trials
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Clin Trials 3:543-51. 2006
  8. ncbi Utilization and outcomes of the implantable cardioverter defibrillator, 1987 to 1995
    Mark A Hlatky
    Department of Health Research and Policy, School of Medicine, Stanford University, Stanford 94305 5405, USA
    Am Heart J 144:397-403. 2002
  9. ncbi The high cost of implantable defibrillators
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Building, Room 150, Stanford, CA 94305 5405, USA
    Eur Heart J 28:388-91. 2007
  10. ncbi Evidence-based medicine and policy: the case of the implantable cardioverter defibrillator
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California, USA
    Health Aff (Millwood) 24:42-51. 2005

Research Grants

  1. ECONOMIC OUTCOMES OF TREATMENT STRATEGIES IN BAR1-2
    Mark Hlatky; Fiscal Year: 2006

Detail Information

Publications92

  1. ncbi Use of medications for secondary prevention after coronary bypass surgery compared with percutaneous coronary intervention
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    J Am Coll Cardiol 61:295-301. 2013
    ..This study sought to compare use of evidence-based secondary preventive medications after coronary bypass surgery (CABG) and percutaneous coronary intervention (PCI)...
  2. ncbi Epidemiologic and statistical methods for comparative effectiveness research
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Heart Fail Clin 9:29-36. 2013
    ..These approaches will never eliminate the need for randomized trials, but clearly have a role in evaluating the effect of therapies in unselected populations treated in routine practice...
  3. ncbi Future directions for cardiovascular disease comparative effectiveness research: report of a workshop sponsored by the National Heart, Lung, and Blood Institute
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    J Am Coll Cardiol 60:569-80. 2012
    ....
  4. ncbi Characterizing the admixed African ancestry of African Americans
    Fouad Zakharia
    Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Genome Biol 10:R141. 2009
    ..To focus on African ancestry, we reduced the data to include only those genotypes in each African American determined statistically to be African in origin...
  5. ncbi Economic evaluation in long-term clinical trials
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Stat Med 21:2879-88. 2002
    ..A model that projects long-term patterns of cost and survival expected beyond the end of completed follow-up can provide an important perspective in the setting of limited trial duration...
  6. ncbi Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1035-42. 2007
    ..The goal of this study was to assess whether polymorphisms in genes encoding elements of pathways mediating the response to ischemia affect vulnerability to MI among patients with underlying CAD...
  7. ncbi Cost-effectiveness as an outcome in randomized clinical trials
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Clin Trials 3:543-51. 2006
    ..Economic outcomes are now included in many contemporary randomized trials and provide an additional dimension to the assessment of interventions. Economic data collection and analysis pose several methodologic challenges, however...
  8. ncbi Utilization and outcomes of the implantable cardioverter defibrillator, 1987 to 1995
    Mark A Hlatky
    Department of Health Research and Policy, School of Medicine, Stanford University, Stanford 94305 5405, USA
    Am Heart J 144:397-403. 2002
    ..The purpose of this study was to document the impact of the ICD in widespread clinical practice...
  9. ncbi The high cost of implantable defibrillators
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Building, Room 150, Stanford, CA 94305 5405, USA
    Eur Heart J 28:388-91. 2007
    ..The cost-effectiveness of ICDs would be improved by development of simpler and cheaper devices, and by better tools to identify patients who benefit from an ICD...
  10. ncbi Evidence-based medicine and policy: the case of the implantable cardioverter defibrillator
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California, USA
    Health Aff (Millwood) 24:42-51. 2005
    ....
  11. ncbi Medical costs and quality of life 10 to 12 years after randomization to angioplasty or bypass surgery for multivessel coronary artery disease
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Building, Room 150, Stanford, CA 94305 5405, USA
    Circulation 110:1960-6. 2004
    ..Coronary bypass surgery (CABG) and angioplasty (PTCA) have been compared in several randomized trials, but data about long-term economic and quality-of-life outcomes are limited...
  12. ncbi Economic evaluation of alternative strategies to treat patients with diabetes mellitus and coronary artery disease
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California 94305 5405, USA
    Am J Cardiol 97:59G-65G. 2006
    ....
  13. ncbi Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1043-51. 2007
    ..The aim of this study was to assess systematic differences between patients with acute myocardial infarction (MI) and patients with stable angina in matrix metalloproteinase (MMP) circulating levels and genetic polymorphisms...
  14. ncbi Economic endpoints in clinical trials
    Mark A Hlatky
    Department of Health Research and Policy, Department of Medicine, Stanford University School of Medicine, HRP Redwood Building, Room 150, Stanford, CA 94305 5405, USA
    Epidemiol Rev 24:80-4. 2002
    ..These developments will be stimulated by the demands of the public for efficient and effective medical care, which will be based on the findings of clinical trials...
  15. ncbi Employment after coronary angioplasty or coronary bypass surgery in patients employed at the time of revascularization
    M A Hlatky
    Stanford University School of Medicine, California 94305 5405, USA
    Ann Intern Med 129:543-7. 1998
    ..Patients who undergo coronary angioplasty have a shorter convalescence than those who undergo coronary bypass surgery. This may improve subsequent employment...
  16. ncbi Physician procedure volume and complications of cardioverter-defibrillator implantation
    James V Freeman
    Stanford University School of Medicine, HRP Redwood Bldg, Room T150, 259 Campus Dr, Stanford, CA 94305 5405, USA
    Circulation 125:57-64. 2012
    ..We assessed whether the rate of complications after implantable cardioverter-defibrillator (ICD) placement varied with the volume of procedures a physician performed...
  17. ncbi Clinical correlates of the initial and long-term cost of coronary bypass surgery and coronary angioplasty
    M A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, HRP Redwood Bldg, Room 150, Stanford, 94305 5405, USA
    Am Heart J 138:376-83. 1999
    ..Understanding the postprocedure events that increase cost should help to improve efficiency and effectiveness of coronary revascularization...
  18. ncbi Cost-effectiveness of the implantable cardioverter defibrillator
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, CA 94305 5405, USA
    Card Electrophysiol Rev 7:479-82. 2003
    ..A rough rule of thumb is that the ICD will be economically attractive when it prolongs mean survival by six months or more, which is attainable in higher risk patient subgroups...
  19. ncbi The effect of internal thoracic artery grafts on long-term clinical outcomes after coronary bypass surgery
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    J Thorac Cardiovasc Surg 142:829-35. 2011
    ..We sought to compare long-term outcomes after coronary bypass surgery with and without an internal thoracic artery graft...
  20. ncbi Economic outcomes of treatment strategies for type 2 diabetes mellitus and coronary artery disease in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Circulation 120:2550-8. 2009
    ..The economic outcomes of clinical management strategies are important in assessing their value to patients...
  21. ncbi Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy: results from the Heart and Estrogen/Progestin Replacement Study (HERS) trial
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Bldg, Room 150, Stanford, CA 94305 5405, USA
    JAMA 287:591-7. 2002
    ..Postmenopausal hormone therapy is commonly used by women for disease prevention, but its effects on quality of life have not been well documented...
  22. ncbi The effect of obesity on quality of life in patients with diabetes and coronary artery disease
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 159:292-300. 2010
    ..Obesity increases the risk of type 2 diabetes and coronary artery disease (CAD). Because all 3 conditions may reduce quality of life, the extent to which obesity, diabetes, and CAD independently affect quality of life is uncertain...
  23. ncbi Management of ventricular arrhythmias in diverse populations in California
    Mark Alexander
    Medical Effectiveness Research Center for Diverse Populations, Department of Medicine, University of California, San Francisco, Calif, USA
    Am Heart J 144:431-9. 2002
    ..CONCLUSIONS: In a large population of patients hospitalized for ventricular arrhythmia, blacks had significantly lower rates of utilization for EPS and ICD procedures and higher subsequent mortality rates...
  24. ncbi Effectiveness and cost-effectiveness of implantable cardioverter defibrillators in the treatment of ventricular arrhythmias among medicare beneficiaries
    J Peter Weiss
    Department of Health Research and Policy, Stanford, California 94305-5405, USA
    Am J Med 112:519-27. 2002
    ..CONCLUSION: The use of implantable defibrillators was associated with significantly lower mortality and higher costs, whereas the cost-effectiveness was higher than many, but not all, generally accepted therapies...
  25. ncbi Distributed decision support using a web-based interface: prevention of sudden cardiac death
    G D Sanders
    Center for Primary Care and Outcomes Research, Department of Medicine, Stanford University, California 94305 5405, USA
    Med Decis Making 19:157-66. 1999
    ....
  26. ncbi Cost-effectiveness of bypass surgery versus stenting in patients with multivessel coronary artery disease
    Cynthia A Yock
    Center for Primary Care and Outcomes Research, Stanford University School of Medicine, Stanford, California 94305, USA
    Am J Med 115:382-9. 2003
    ..CONCLUSION: Bypass surgery results in better outcomes than angioplasty in patients with multivessel disease, and at a lower cost...
  27. ncbi Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction
    Joshua W Knowles
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1052-8. 2007
    ..Genetic polymorphisms may affect the balance between coagulation and fibrinolysis and thereby affect individual vulnerability to acute myocardial infarction (MI) among patients with underlying coronary atherosclerosis...
  28. ncbi Does enrollment in a randomized clinical trial lead to a higher cost of routine care?
    J Peter Weiss
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, Calif 94305 5405, USA
    Am Heart J 143:140-4. 2002
    ..Reimbursement for the routine care of patients enrolled in clinical trials is controversial. Our objective was to determine the added medical costs, if any, associated with enrollment in a randomized clinical trial...
  29. ncbi Do plasma biomarkers of coagulation and fibrinolysis differ between patients who have experienced an acute myocardial infarction versus stable exertional angina?
    Haruka Itakura
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1059-64. 2007
    ..Circulating concentrations of proteins associated with coagulation and fibrinolysis may differ between individuals with coronary artery disease (CAD) who develop an acute myocardial infarction (AMI) rather than stable exertional angina...
  30. ncbi Cognitive function 5 years after randomization to coronary angioplasty or coronary artery bypass graft surgery
    M A Hlatky
    Stanford University School of Medicine, Calif 94305 5092, USA
    Circulation 96:II-11-4; discussion II-15. 1997
    ..The purpose of this study was to compare cognitive function 5 years after randomization to a strategy of either initial coronary surgery or initial angioplasty...
  31. ncbi Meta-analysis of trials comparing beta-blockers, calcium antagonists, and nitrates for stable angina
    P A Heidenreich
    Veterans Affairs Palo Alto Health Care System, Calif, USA
    JAMA 281:1927-36. 1999
    ..Which drug is most effective as a first-line treatment for stable angina is not known...
  32. ncbi The prognostic value of troponin in patients with non-ST elevation acute coronary syndromes: a meta-analysis
    P A Heidenreich
    Veterans Affairs Palo Alto Health Care System, California 94304, USA
    J Am Coll Cardiol 38:478-85. 2001
    ..This study was designed to compare the prognostic value of an abnormal troponin level derived from studies of patients with non-ST elevation acute coronary syndromes (ACS)...
  33. ncbi Isolated disease of the proximal left anterior descending artery comparing the effectiveness of percutaneous coronary interventions and coronary artery bypass surgery
    John R Kapoor
    Department of Cardiology, Stanford University School of Medicine, California, USA
    JACC Cardiovasc Interv 1:483-91. 2008
    ..This study sought to systematically compare the effectiveness of percutaneous coronary intervention and coronary artery bypass surgery in patients with single-vessel disease of the proximal left anterior descending (LAD) coronary artery...
  34. ncbi Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, California 94304 1334, USA
    J Am Coll Cardiol 56:1552-63. 2010
    ..We sought to replicate the association between the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism (rs20455), and clinical coronary artery disease (CAD)...
  35. ncbi Trends in hospital treatment of ventricular arrhythmias among Medicare beneficiaries, 1985 to 1995
    Kathryn M McDonald
    Health Research and Policy, and the Department of Medicine, Stanford University School of Medicine, Stanford, Calif, USA
    Am Heart J 144:413-21. 2002
    ..Treatment options for patients with ventricular arrhythmias have undergone major changes in the last 2 decades. Trends in use of invasive procedures, clinical outcomes, and expenditures have not been well documented...
  36. ncbi Validation of a new brief physical activity survey among men and women aged 60-69 years
    Ruth E Taylor-Piliae
    Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94303 5705, USA
    Am J Epidemiol 164:598-606. 2006
    ....
  37. ncbi Insulin resistance independently predicts the progression of coronary artery calcification
    Keane K Lee
    Stanford University School of Medicine, Stanford, CA, USA
    Am Heart J 157:939-45. 2009
    ..Change in coronary artery calcification is a surrogate marker of subclinical coronary artery disease (CAD). In the only large prospective study, CAD risk factors predicted progression of coronary artery calcium (CAC)...
  38. ncbi Systematic review: the comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery
    Dena M Bravata
    Center for Primary Care and Outcomes Research and Stanford University School of Medicine, Stanford, California 94305 6019, USA
    Ann Intern Med 147:703-16. 2007
    ..The comparative effectiveness of coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI) for patients in whom both procedures are feasible remains poorly understood...
  39. ncbi Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Hum Mol Genet 17:2320-8. 2008
    ..Further investigations in other populations are needed to confirm or refute our findings...
  40. ncbi A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Atherosclerosis 198:136-44. 2008
    ..We tested the hypothesis that exonic and/or promoter single nucleotide polymorphisms (SNPs) in the human 12/15-LOX gene (ALOX15) alter the risk of symptomatic coronary artery disease (CAD)...
  41. ncbi Clinical utility of the Stanford brief activity survey in men and women with early-onset coronary artery disease
    Ruth E Taylor-Piliae
    Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94305 5705, USA
    J Cardiopulm Rehabil Prev 27:227-32. 2007
    ..To determine the utility of the Stanford Brief Activity Survey (SBAS) as a quick screening tool in a clinical population, where no other measure of physical activity was available...
  42. ncbi Quality of life and time trade-off utility measures in patients with coronary artery disease
    Kathryn A Melsop
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, Calif 95305-5405, USA
    Am Heart J 145:36-41. 2003
    ..29), 5 (r2 = 0.31), or 6 (r2 = 0.32) variables. CONCLUSIONS: Time trade-off utility scores can be inferred from commonly used quality-of-life measures. Angina significantly reduces patient utility scores...
  43. ncbi The relation between hospital procedure volume and complications of cardioverter-defibrillator implantation from the implantable cardioverter-defibrillator registry
    James V Freeman
    Stanford University School of Medicine, California, USA
    J Am Coll Cardiol 56:1133-9. 2010
    ..We sought to examine the relationship between hospital implantable cardioverter-defibrillator (ICD) implantation volume and procedural complications in a contemporary, representative population...
  44. ncbi Effect of race on the clinical outcomes in the bypass angioplasty revascularization investigation trial
    Kathryn Melsop
    Stanford University School of Medicine, Stanford, Calif, USA
    Circ Cardiovasc Qual Outcomes 2:186-90. 2009
    ..There are few data from randomized trials comparing the outcomes of coronary revascularization between black patients and white patients...
  45. ncbi Repeat coronary revascularization procedures after successful bare-metal or drug-eluting stent implantation
    Cynthia A Yock
    Department of Health Policy, Stanford University School of Medicine, Stanford California 94305 6019, USA
    J Invasive Cardiol 22:27-33. 2010
    ..Randomized trials provide a reference standard for comparing outcomes after BMS or DES, but the rates of repeat revascularization procedures in clinical trials do not necessarily represent the rates in routine practice...
  46. ncbi Overview of randomized trials of antiarrhythmic drugs and devices for the prevention of sudden cardiac death
    Paul A Heidenreich
    Department of Medicine, Stanford University School of Medicine, Stanford, Calif 94305-5405, USA
    Am Heart J 144:422-30. 2002
    ..CONCLUSION: Amiodarone is effective in reducing the total mortality rate by 13% to 19%, and the implantable defibrillator reduces the mortality rate by a further 24%...
  47. ncbi Ethnic differences in coronary artery calcium in a healthy cohort aged 60 to 69 years
    Joan M Fair
    Stanford Prevention Research Center, Stanford University, Department of Radiology, Stanford, California, USA
    Am J Cardiol 100:981-5. 2007
    ..In conclusion, our data indicate that the presence of CAC varied significantly across selected race/ethnic groups independent of traditional cardiovascular risk factors...
  48. ncbi Right coronary wall CMR in the older asymptomatic advance cohort: positive remodeling and associations with type 2 diabetes and coronary calcium
    Masahiro Terashima
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    J Cardiovasc Magn Reson 12:75. 2010
    ..The purpose of the study was to evaluate coronary wall CMR in an asymptomatic older cohort...
  49. ncbi Effect of risk stratification on cost-effectiveness of the implantable cardioverter defibrillator
    Douglas K Owens
    VA Health Care System, Palo Alto, Calif 94304, USA
    Am Heart J 144:440-8. 2002
    ..We evaluated whether risk stratification based on risk of sudden cardiac death alone was sufficient to predict the effectiveness and cost-effectiveness of the ICD...
  50. ncbi Persistent racial disparities in survival after heart transplantation
    Vincent Liu
    Divisions of Pulmonary and Critical Care, Stanford University, CA, USA
    Circulation 123:1642-9. 2011
    ..Racial and ethnic disparities are well documented in many areas of health care, but have not been comprehensively evaluated among recipients of heart transplants...
  51. ncbi Cost-effectiveness of genetic testing in family members of patients with long-QT syndrome
    MARCO V PEREZ
    Center for Inherited Cardiovascular Disease, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA
    Circ Cardiovasc Qual Outcomes 4:76-84. 2011
    ..Genetic testing can identify mutations in 75% of patients with LQTS, but genetic testing of family members remains controversial...
  52. ncbi Patient preferences in coronary revascularization
    J Hornberger
    Departments of Health Research and Policy and of Medicine, Stanford University School of Medicine, CA, USA
    Am Heart J 137:1153-62. 1999
    ..This study was performed to assess patient preferences for consequences of 3 coronary revascularization procedures: angioplasty, conventional coronary bypass surgery, and minimally invasive coronary bypass surgery...
  53. ncbi Potential cost-effectiveness of prophylactic use of the implantable cardioverter defibrillator or amiodarone after myocardial infarction
    G D Sanders
    Center for Primary Care and Outcomes Research, 179 Encina Commons, Stanford University, Stanford, CA 94305 6019, USA
    Ann Intern Med 135:870-83. 2001
    ..Clinical trials have shown that implantable cardioverter defibrillators (ICDs) improve survival in patients with sustained ventricular arrhythmias...
  54. ncbi Distribution of asymmetric dimethylarginine among 980 healthy, older adults of different ethnicities
    Karsten Sydow
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Clin Chem 56:111-20. 2010
    ..However, the majority of studies investigating the clinical role of ADMA were performed in European study populations with few individuals of other ethnicities...
  55. ncbi Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trials
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA, USA
    Lancet 373:1190-7. 2009
    ..We undertook a collaborative analysis of data from randomised trials to assess whether the effects of the procedures on mortality are modified by patient characteristics...
  56. ncbi Cost-effectiveness of preparticipation screening for prevention of sudden cardiac death in young athletes
    Matthew T Wheeler
    Stanford University, California 94305, USA
    Ann Intern Med 152:276-86. 2010
    ..Inclusion of 12-lead electrocardiography (ECG) in preparticipation screening of young athletes is controversial because of concerns about cost-effectiveness...
  57. ncbi Incidental findings on cardiac multidetector row computed tomography among healthy older adults: prevalence and clinical correlates
    Jeremy R Burt
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Arch Intern Med 168:756-61. 2008
    ..Our objectives were to evaluate the prevalence of incidental findings discovered during cardiac MDCT scanning and to identify clinical variables associated with incidental findings...
  58. ncbi Facility factors dominate the ability to achieve target haemoglobin levels in haemodialysis patients
    Kevin E Chan
    Division of Nephrology, Stanford University School of Medicine, 300 Pasteur Drive, S161, Stanford, CA 94305 5114, USA
    Nephrol Dial Transplant 23:2948-56. 2008
    ..Our objective was to determine whether patient factors, processes of care and measures of erythropoietin (EPO) responsiveness were associated with successful anemia management at the individual patient level...
  59. ncbi Evidence-based use of cardiac procedures and devices
    Mark A Hlatky
    Donald W. Reynolds Cardiovascular Clinical Research Center, Stanford University School of Medicine, Stanford, Calif, USA
    N Engl J Med 350:2126-8. 2004
  60. ncbi Physical and sexual function in women with chronic kidney disease
    Manjula Kurella
    Department of Medicine, University of California San Francisco, San Francisco, CA 94118-1211, USA
    Am J Kidney Dis 43:868-76. 2004
    ..CONCLUSION: CKD is associated with impaired physical function, and a decline in estimated GFR is associated with a decline in physical function...
  61. ncbi Life after a ventricular arrhythmia
    John Hsu
    Division of Research, Kaiser Permanente, Oakland, Calif 94611 5714, USA
    Am Heart J 144:404-12. 2002
    ..We evaluated patients' quality of life (QOL) and medical costs after hospitalization and treatment for their first episode of an LTVA...
  62. ncbi Cost-effectiveness of coronary artery bypass grafts versus percutaneous coronary intervention for revascularization of high-risk patients
    Kevin T Stroupe
    Cooperative Studies Program Coordinating Center, Hines VA Hospital, PO Box 5000 151H, Hines, IL 60141, USA
    Circulation 114:1251-7. 2006
    ..The present study examined the cost-effectiveness of PCI versus CABG for these high-risk patients...
  63. ncbi Improvement in quality of life after radiofrequency ablation
    Mark A Hlatky
    Pacing Clin Electrophysiol 29:341-2. 2006
  64. ncbi Differences in medical care and disease outcomes among black and white women with heart disease
    Ashish K Jha
    Division of General Medicine, San Francisco VA Medical Center, San Francisco, USA
    Circulation 108:1089-94. 2003
    ..We sought to evaluate differences in medical care and clinical outcomes among black and white women with established coronary artery disease...
  65. ncbi Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: Section 5: gender-related risk factors for ischemic heart disease
    Leslee J Shaw
    Circulation 109:e56-8. 2004
  66. ncbi Cost-effectiveness of implantable cardioverter-defibrillators
    Gillian D Sanders
    Duke Clinical Research Institute, Duke University, Durham, NC 27715, USA
    N Engl J Med 353:1471-80. 2005
    ..We assessed the cost-effectiveness of the ICD in the populations represented in these primary-prevention trials...
  67. ncbi Comorbidity and outcome in patients with coronary artery disease
    Mark A Hlatky
    J Am Coll Cardiol 43:583-4. 2004
  68. ncbi Conducting economic evaluations alongside multinational clinical trials: toward a research consensus
    Shelby D Reed
    Center for Clinical and Genetic Economics, Duke University Medical Centre, Durham, NC, USA
    Am Heart J 149:434-43. 2005
    ..Delineation of the various approaches to multinational economic evaluation may assist researchers, peer reviewers, journal editors, and decision makers in evaluating the strengths and limitations of particular studies...
  69. ncbi Calcium, vitamin D supplementation, and physical function in the Women's Health Initiative
    Robert L Brunner
    University of Nevada School of Medicine, PMB 251, MS 145, Reno, NV 89557, USA
    J Am Diet Assoc 108:1472-9. 2008
    ..Now we examine whether the treatment affected self-reported physical functioning and objective measures of physical functioning...
  70. ncbi Cost-effectiveness of a conservative, ischemia-guided management strategy after non-Q-wave myocardial infarction: results of a randomized trial
    Paul G Barnett
    VA Palo Alto Health Care System, Palo Alto, Calif, USA
    Circulation 105:680-4. 2002
    ....
  71. ncbi Preventing tomorrow's sudden cardiac death today: part II: Translating sudden cardiac death risk assessment strategies into practice and policy
    Gillian D Sanders
    Duke Clinical Research Institute, Duke Medical Center, Durham, NC 27715, USA
    Am Heart J 153:951-9. 2007
    ....
  72. ncbi Medical economics and the assessment of value in cardiovascular medicine: Part II
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 106:626-30. 2002
  73. ncbi Medical economics and the assessment of value in cardiovascular medicine: Part I
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 106:516-20. 2002
  74. ncbi ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Cl
    Philip Greenland
    Circulation 115:402-26. 2007
  75. ncbi Risk of sudden versus nonsudden cardiac death in patients with coronary artery disease
    Nathan Every
    Department of Biostatistics, Northwest Health Services Research and Development Center of Excellence, VA Puget Sound Healthcare System, University of Washington, Seattle, Wash, USA
    Am Heart J 144:390-6. 2002
    ..62). CONCLUSION: Standard clinical evaluation is much better at predicting overall risk of death than at predicting the mode of death as sudden or nonsudden...
  76. ncbi Plasma leptin levels and coronary artery calcification in older adults
    Carlos Iribarren
    Kaiser Permanente, Division of Research, 2000 Broadway, Oakland, California 94612, USA
    J Clin Endocrinol Metab 92:729-32. 2007
    ..Leptin is associated with adiposity and insulin resistance and may play a direct role in vascular calcification. It is unclear, however, whether leptin is an independent predictor of atherosclerotic burden...
  77. ncbi Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts?
    Carlos Iribarren
    Kaiser Permanente Division of Research, Oakland, California 94612, USA
    J Am Coll Cardiol 48:1800-7. 2006
    ....
  78. ncbi Self-rated health among women with coronary disease: depression is as important as recent cardiovascular events
    Bernice Ruo
    Division of General Internal Medicine, Department of Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611-2927, USA
    Am Heart J 152:921.e1-7. 2006
    ..CONCLUSIONS: Women with persistent or new depression are more likely to report fair/poor self-rated health. The magnitude of the impact of persistent or new depression is comparable to that of major cardiac events...
  79. ncbi Depressive symptoms and health-related quality of life: the Heart and Soul Study
    Bernice Ruo
    Section of General Internal Medicine, Veterans Affairs Medical Center, San Francisco 94121, USA
    JAMA 290:215-21. 2003
    ..Conversely, 2 traditional measures of cardiac function-ejection fraction and ischemia-are not. Efforts to improve health status should include assessment and treatment of depressive symptoms...
  80. ncbi Statin and beta-blocker therapy and the initial presentation of coronary heart disease
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, California 94612 2304, USA
    Ann Intern Med 144:229-38. 2006
    ..Patients who present with unstable coronary disease, such as acute myocardial infarction, may systematically differ from patients who present with relatively stable coronary disease, such as exertional angina...
  81. ncbi Effect of postmenopausal hormone therapy on coronary heart disease events after percutaneous transluminal coronary angioplasty
    Masroor A Khan
    Cardiology Division, The University of Texas Health Center, 11937 US Highway 271, Tyler, TX 75708, USA
    Am J Cardiol 91:989-91, A7. 2003
  82. ncbi ACC/AHA/NASPE 2002 guideline update for implantation of cardiac pacemakers and antiarrhythmia devices: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to
    Gabriel Gregoratos
    Circulation 106:2145-61. 2002
  83. ncbi Coronary revascularization and quality of life
    Mark A Hlatky
    Am Heart J 148:5-6. 2004
  84. ncbi Health-related quality of life in patients with pulmonary arterial hypertension
    Shirin Shafazand
    The George Washington University, Washington Hospital Center, Washington, DC, USA
    Chest 126:1452-9. 2004
    ..This study describes HRQOL in a cohort of patients with PAH...
  85. ncbi A systematic review of the economic burden of chronic angina
    Matthew W Reynolds
    MetaWorks Inc, Medford, Massachusetts, USA
    Am J Manag Care 10:S347-57. 2004
    ..Workplace productivity loss because of angina is also substantial, but lasting long-term improvement in work status has been difficult to achieve...
  86. ncbi Integrating complementary medicine into cardiovascular medicine. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (Writing Committee to Develop an Expert Consensus Document on Complementary and In
    John H K Vogel
    J Am Coll Cardiol 46:184-221. 2005
  87. ncbi Cost effectiveness of cardiac resynchronization therapy
    Mark A Hlatky
    J Am Coll Cardiol 46:2322-4. 2005
  88. ncbi Underuse of evidence-based therapies
    Mark A Hlatky
    Circulation 110:644-5. 2004
  89. ncbi ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline
    Andrew E Epstein
    J Am Coll Cardiol 51:e1-62. 2008
  90. ncbi ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline
    Andrew E Epstein
    Circulation 117:e350-408. 2008
  91. ncbi ACC/AHA/HRS 2008 Guidelines for device-based therapy of cardiac rhythm abnormalities
    Andrew E Epstein
    Heart Rhythm 5:e1-62. 2008

Research Grants1

  1. ECONOMIC OUTCOMES OF TREATMENT STRATEGIES IN BAR1-2
    Mark Hlatky; Fiscal Year: 2006
    ..The investigators further expect that this collaborative effort will translate into a new practical clinical paradigm that will be used for treatment of Type II diabetic patients. ..