M A Hlatky

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Economic outcomes in the Study of Myocardial Perfusion and Coronary Anatomy Imaging Roles in Coronary Artery Disease registry: the SPARC Study
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California Electronic address
    J Am Coll Cardiol 63:1002-8. 2014
  2. pmc Adoption and effectiveness of internal mammary artery grafting in coronary artery bypass surgery among Medicare beneficiaries
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California Electronic address
    J Am Coll Cardiol 63:33-9. 2014
  3. pmc Incremental prognostic information from kidney function in patients with new onset coronary heart disease
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA Electronic address
    Am Heart J 167:86-92. 2014
  4. pmc Comparative effectiveness of multivessel coronary bypass surgery and multivessel percutaneous coronary intervention: a cohort study
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Ann Intern Med 158:727-34. 2013
  5. doi request reprint Volume, outcome, and policy
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Building, Rm T150, 259 Campus Drive, Stanford, CA 94305 5405, USA
    J Interv Card Electrophysiol 36:151-5. 2013
  6. doi request reprint Use of medications for secondary prevention after coronary bypass surgery compared with percutaneous coronary intervention
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    J Am Coll Cardiol 61:295-301. 2013
  7. pmc Epidemiologic and statistical methods for comparative effectiveness research
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Heart Fail Clin 9:29-36. 2013
  8. pmc Future directions for cardiovascular disease comparative effectiveness research: report of a workshop sponsored by the National Heart, Lung, and Blood Institute
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    J Am Coll Cardiol 60:569-80. 2012
  9. pmc Characterizing the admixed African ancestry of African Americans
    Fouad Zakharia
    Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Genome Biol 10:R141. 2009
  10. ncbi request reprint Economic evaluation in long-term clinical trials
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Stat Med 21:2879-88. 2002

Research Grants

Detail Information

Publications97

  1. ncbi request reprint Economic outcomes in the Study of Myocardial Perfusion and Coronary Anatomy Imaging Roles in Coronary Artery Disease registry: the SPARC Study
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California Electronic address
    J Am Coll Cardiol 63:1002-8. 2014
    ..The goal of this study was to compare the economic outcomes of patients undergoing different noninvasive tests to evaluate suspected coronary artery disease (CAD)...
  2. pmc Adoption and effectiveness of internal mammary artery grafting in coronary artery bypass surgery among Medicare beneficiaries
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California Electronic address
    J Am Coll Cardiol 63:33-9. 2014
    ....
  3. pmc Incremental prognostic information from kidney function in patients with new onset coronary heart disease
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA Electronic address
    Am Heart J 167:86-92. 2014
    ..The extent to which estimated glomerular filtration rate (eGFR) adds information about prognosis among patients with coronary heart disease is uncertain...
  4. pmc Comparative effectiveness of multivessel coronary bypass surgery and multivessel percutaneous coronary intervention: a cohort study
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Ann Intern Med 158:727-34. 2013
    ..Randomized trials of coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI) suggest that patient characteristics modify the effect of treatment on mortality...
  5. doi request reprint Volume, outcome, and policy
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Building, Rm T150, 259 Campus Drive, Stanford, CA 94305 5405, USA
    J Interv Card Electrophysiol 36:151-5. 2013
    ..Increased procedure volume for implantable defibrillators has been associated with lower short-term complication rates. The controversial policy implications of these observations are discussed...
  6. doi request reprint Use of medications for secondary prevention after coronary bypass surgery compared with percutaneous coronary intervention
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    J Am Coll Cardiol 61:295-301. 2013
    ..This study sought to compare use of evidence-based secondary preventive medications after coronary bypass surgery (CABG) and percutaneous coronary intervention (PCI)...
  7. pmc Epidemiologic and statistical methods for comparative effectiveness research
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Heart Fail Clin 9:29-36. 2013
    ..These approaches will never eliminate the need for randomized trials, but clearly have a role in evaluating the effect of therapies in unselected populations treated in routine practice...
  8. pmc Future directions for cardiovascular disease comparative effectiveness research: report of a workshop sponsored by the National Heart, Lung, and Blood Institute
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    J Am Coll Cardiol 60:569-80. 2012
    ....
  9. pmc Characterizing the admixed African ancestry of African Americans
    Fouad Zakharia
    Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Genome Biol 10:R141. 2009
    ..To focus on African ancestry, we reduced the data to include only those genotypes in each African American determined statistically to be African in origin...
  10. ncbi request reprint Economic evaluation in long-term clinical trials
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Stat Med 21:2879-88. 2002
    ..A model that projects long-term patterns of cost and survival expected beyond the end of completed follow-up can provide an important perspective in the setting of limited trial duration...
  11. pmc Economic outcomes of treatment strategies for type 2 diabetes mellitus and coronary artery disease in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Circulation 120:2550-8. 2009
    ..The economic outcomes of clinical management strategies are important in assessing their value to patients...
  12. ncbi request reprint Economic endpoints in clinical trials
    Mark A Hlatky
    Department of Health Research and Policy, Department of Medicine, Stanford University School of Medicine, HRP Redwood Building, Room 150, Stanford, CA 94305 5405, USA
    Epidemiol Rev 24:80-4. 2002
    ..These developments will be stimulated by the demands of the public for efficient and effective medical care, which will be based on the findings of clinical trials...
  13. ncbi request reprint Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1043-51. 2007
    ..The aim of this study was to assess systematic differences between patients with acute myocardial infarction (MI) and patients with stable angina in matrix metalloproteinase (MMP) circulating levels and genetic polymorphisms...
  14. ncbi request reprint Cost-effectiveness as an outcome in randomized clinical trials
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Clin Trials 3:543-51. 2006
    ..Economic outcomes are now included in many contemporary randomized trials and provide an additional dimension to the assessment of interventions. Economic data collection and analysis pose several methodologic challenges, however...
  15. ncbi request reprint The high cost of implantable defibrillators
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Building, Room 150, Stanford, CA 94305 5405, USA
    Eur Heart J 28:388-91. 2007
    ..The cost-effectiveness of ICDs would be improved by development of simpler and cheaper devices, and by better tools to identify patients who benefit from an ICD...
  16. ncbi request reprint Cost-effectiveness of the implantable cardioverter defibrillator
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, CA 94305 5405, USA
    Card Electrophysiol Rev 7:479-82. 2003
    ..A rough rule of thumb is that the ICD will be economically attractive when it prolongs mean survival by six months or more, which is attainable in higher risk patient subgroups...
  17. ncbi request reprint Economic evaluation of alternative strategies to treat patients with diabetes mellitus and coronary artery disease
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California 94305 5405, USA
    Am J Cardiol 97:59G-65G. 2006
    ....
  18. ncbi request reprint Evidence-based medicine and policy: the case of the implantable cardioverter defibrillator
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, California, USA
    Health Aff (Millwood) 24:42-51. 2005
    ....
  19. doi request reprint The effect of obesity on quality of life in patients with diabetes and coronary artery disease
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 159:292-300. 2010
    ..Obesity increases the risk of type 2 diabetes and coronary artery disease (CAD). Because all 3 conditions may reduce quality of life, the extent to which obesity, diabetes, and CAD independently affect quality of life is uncertain...
  20. doi request reprint The effect of internal thoracic artery grafts on long-term clinical outcomes after coronary bypass surgery
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    J Thorac Cardiovasc Surg 142:829-35. 2011
    ..We sought to compare long-term outcomes after coronary bypass surgery with and without an internal thoracic artery graft...
  21. ncbi request reprint Employment after coronary angioplasty or coronary bypass surgery in patients employed at the time of revascularization
    M A Hlatky
    Stanford University School of Medicine, California 94305 5405, USA
    Ann Intern Med 129:543-7. 1998
    ..Patients who undergo coronary angioplasty have a shorter convalescence than those who undergo coronary bypass surgery. This may improve subsequent employment...
  22. ncbi request reprint Clinical correlates of the initial and long-term cost of coronary bypass surgery and coronary angioplasty
    M A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, HRP Redwood Bldg, Room 150, Stanford, 94305 5405, USA
    Am Heart J 138:376-83. 1999
    ..Understanding the postprocedure events that increase cost should help to improve efficiency and effectiveness of coronary revascularization...
  23. ncbi request reprint Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy: results from the Heart and Estrogen/Progestin Replacement Study (HERS) trial
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Bldg, Room 150, Stanford, CA 94305 5405, USA
    JAMA 287:591-7. 2002
    ..Postmenopausal hormone therapy is commonly used by women for disease prevention, but its effects on quality of life have not been well documented...
  24. ncbi request reprint Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1035-42. 2007
    ..The goal of this study was to assess whether polymorphisms in genes encoding elements of pathways mediating the response to ischemia affect vulnerability to MI among patients with underlying CAD...
  25. ncbi request reprint Medical costs and quality of life 10 to 12 years after randomization to angioplasty or bypass surgery for multivessel coronary artery disease
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Building, Room 150, Stanford, CA 94305 5405, USA
    Circulation 110:1960-6. 2004
    ..Coronary bypass surgery (CABG) and angioplasty (PTCA) have been compared in several randomized trials, but data about long-term economic and quality-of-life outcomes are limited...
  26. doi request reprint Physician procedure volume and complications of cardioverter-defibrillator implantation
    James V Freeman
    Stanford University School of Medicine, HRP Redwood Bldg, Room T150, 259 Campus Dr, Stanford, CA 94305 5405, USA
    Circulation 125:57-64. 2012
    ..We assessed whether the rate of complications after implantable cardioverter-defibrillator (ICD) placement varied with the volume of procedures a physician performed...
  27. ncbi request reprint Utilization and outcomes of the implantable cardioverter defibrillator, 1987 to 1995
    Mark A Hlatky
    Department of Health Research and Policy, School of Medicine, Stanford University, Stanford 94305 5405, USA
    Am Heart J 144:397-403. 2002
    ..The purpose of this study was to document the impact of the ICD in widespread clinical practice...
  28. ncbi request reprint Management of ventricular arrhythmias in diverse populations in California
    Mark Alexander
    Medical Effectiveness Research Center for Diverse Populations, Department of Medicine, University of California, San Francisco, Calif, USA
    Am Heart J 144:431-9. 2002
    ..The use of coronary angiography and revascularization is lower than expected among black patients. It is uncertain whether use of other cardiac procedures also varies according to race and ethnicity and whether outcomes are affected...
  29. ncbi request reprint Effectiveness and cost-effectiveness of implantable cardioverter defibrillators in the treatment of ventricular arrhythmias among medicare beneficiaries
    J Peter Weiss
    Department of Health Research and Policy, Stanford, California 94305 5405, USA
    Am J Med 112:519-27. 2002
    ..Our purpose was to evaluate the outcomes and costs of defibrillator use in an unselected population...
  30. ncbi request reprint Distributed decision support using a web-based interface: prevention of sudden cardiac death
    G D Sanders
    Center for Primary Care and Outcomes Research, Department of Medicine, Stanford University, California 94305 5405, USA
    Med Decis Making 19:157-66. 1999
    ....
  31. ncbi request reprint Cost-effectiveness of bypass surgery versus stenting in patients with multivessel coronary artery disease
    Cynthia A Yock
    Center for Primary Care and Outcomes Research, Stanford University School of Medicine, Stanford, California 94305, USA
    Am J Med 115:382-9. 2003
    ..To compare the cost-effectiveness of surgical and angioplasty-based coronary artery revascularization techniques, in particular, angioplasty with primary stenting...
  32. pmc Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction
    Joshua W Knowles
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1052-8. 2007
    ..Genetic polymorphisms may affect the balance between coagulation and fibrinolysis and thereby affect individual vulnerability to acute myocardial infarction (MI) among patients with underlying coronary atherosclerosis...
  33. ncbi request reprint Does enrollment in a randomized clinical trial lead to a higher cost of routine care?
    J Peter Weiss
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, Calif 94305 5405, USA
    Am Heart J 143:140-4. 2002
    ..Reimbursement for the routine care of patients enrolled in clinical trials is controversial. Our objective was to determine the added medical costs, if any, associated with enrollment in a randomized clinical trial...
  34. ncbi request reprint Do plasma biomarkers of coagulation and fibrinolysis differ between patients who have experienced an acute myocardial infarction versus stable exertional angina?
    Haruka Itakura
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1059-64. 2007
    ..Circulating concentrations of proteins associated with coagulation and fibrinolysis may differ between individuals with coronary artery disease (CAD) who develop an acute myocardial infarction (AMI) rather than stable exertional angina...
  35. ncbi request reprint Potential cost-effectiveness of prophylactic use of the implantable cardioverter defibrillator or amiodarone after myocardial infarction
    G D Sanders
    Center for Primary Care and Outcomes Research, 179 Encina Commons, Stanford University, Stanford, CA 94305 6019, USA
    Ann Intern Med 135:870-83. 2001
    ..Clinical trials have shown that implantable cardioverter defibrillators (ICDs) improve survival in patients with sustained ventricular arrhythmias...
  36. ncbi request reprint Cognitive function 5 years after randomization to coronary angioplasty or coronary artery bypass graft surgery
    M A Hlatky
    Stanford University School of Medicine, Calif 94305 5092, USA
    Circulation 96:II-11-4; discussion II-15. 1997
    ..The purpose of this study was to compare cognitive function 5 years after randomization to a strategy of either initial coronary surgery or initial angioplasty...
  37. ncbi request reprint Meta-analysis of trials comparing beta-blockers, calcium antagonists, and nitrates for stable angina
    P A Heidenreich
    Veterans Affairs Palo Alto Health Care System, Calif, USA
    JAMA 281:1927-36. 1999
    ..Which drug is most effective as a first-line treatment for stable angina is not known...
  38. ncbi request reprint The prognostic value of troponin in patients with non-ST elevation acute coronary syndromes: a meta-analysis
    P A Heidenreich
    Veterans Affairs Palo Alto Health Care System, California 94304, USA
    J Am Coll Cardiol 38:478-85. 2001
    ..This study was designed to compare the prognostic value of an abnormal troponin level derived from studies of patients with non-ST elevation acute coronary syndromes (ACS)...
  39. pmc Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Hum Mol Genet 17:2320-8. 2008
    ..Further investigations in other populations are needed to confirm or refute our findings...
  40. pmc Effect of race on the clinical outcomes in the bypass angioplasty revascularization investigation trial
    Kathryn Melsop
    Stanford University School of Medicine, Stanford, Calif, USA
    Circ Cardiovasc Qual Outcomes 2:186-90. 2009
    ..There are few data from randomized trials comparing the outcomes of coronary revascularization between black patients and white patients...
  41. ncbi request reprint Effect of risk stratification on cost-effectiveness of the implantable cardioverter defibrillator
    Douglas K Owens
    VA Health Care System, Palo Alto, Calif 94304, USA
    Am Heart J 144:440-8. 2002
    ..We evaluated whether risk stratification based on risk of sudden cardiac death alone was sufficient to predict the effectiveness and cost-effectiveness of the ICD...
  42. doi request reprint Isolated disease of the proximal left anterior descending artery comparing the effectiveness of percutaneous coronary interventions and coronary artery bypass surgery
    John R Kapoor
    Department of Cardiology, Stanford University School of Medicine, California, USA
    JACC Cardiovasc Interv 1:483-91. 2008
    ..This study sought to systematically compare the effectiveness of percutaneous coronary intervention and coronary artery bypass surgery in patients with single-vessel disease of the proximal left anterior descending (LAD) coronary artery...
  43. ncbi request reprint Quality of life and time trade-off utility measures in patients with coronary artery disease
    Kathryn A Melsop
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, Calif 95305 5405, USA
    Am Heart J 145:36-41. 2003
    ..Because utilities are not often measured directly, we sought to develop a method of translating standard quality-of-life scales into a patient utility measure...
  44. ncbi request reprint Clinical utility of the Stanford brief activity survey in men and women with early-onset coronary artery disease
    Ruth E Taylor-Piliae
    Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94305 5705, USA
    J Cardiopulm Rehabil Prev 27:227-32. 2007
    ..To determine the utility of the Stanford Brief Activity Survey (SBAS) as a quick screening tool in a clinical population, where no other measure of physical activity was available...
  45. ncbi request reprint Ethnic differences in coronary artery calcium in a healthy cohort aged 60 to 69 years
    Joan M Fair
    Stanford Prevention Research Center, Stanford University, Department of Radiology, Stanford, California, USA
    Am J Cardiol 100:981-5. 2007
    ..In conclusion, our data indicate that the presence of CAC varied significantly across selected race/ethnic groups independent of traditional cardiovascular risk factors...
  46. ncbi request reprint Systematic review: the comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery
    Dena M Bravata
    Center for Primary Care and Outcomes Research and Stanford University School of Medicine, Stanford, California 94305 6019, USA
    Ann Intern Med 147:703-16. 2007
    ..The comparative effectiveness of coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI) for patients in whom both procedures are feasible remains poorly understood...
  47. pmc A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Atherosclerosis 198:136-44. 2008
    ..We tested the hypothesis that exonic and/or promoter single nucleotide polymorphisms (SNPs) in the human 12/15-LOX gene (ALOX15) alter the risk of symptomatic coronary artery disease (CAD)...
  48. ncbi request reprint Repeat coronary revascularization procedures after successful bare-metal or drug-eluting stent implantation
    Cynthia A Yock
    Department of Health Policy, Stanford University School of Medicine, Stanford California 94305 6019, USA
    J Invasive Cardiol 22:27-33. 2010
    ..Randomized trials provide a reference standard for comparing outcomes after BMS or DES, but the rates of repeat revascularization procedures in clinical trials do not necessarily represent the rates in routine practice...
  49. ncbi request reprint Overview of randomized trials of antiarrhythmic drugs and devices for the prevention of sudden cardiac death
    Paul A Heidenreich
    Department of Medicine, Stanford University School of Medicine, Stanford, Calif 94305 5405, USA
    Am Heart J 144:422-30. 2002
    ..Sudden cardiac death is a prominent feature of the natural history of heart disease. The efficacy of antiarrhythmic drugs and devices in preventing sudden death and reducing total mortality is uncertain...
  50. ncbi request reprint Validation of a new brief physical activity survey among men and women aged 60-69 years
    Ruth E Taylor-Piliae
    Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94303 5705, USA
    Am J Epidemiol 164:598-606. 2006
    ....
  51. pmc Persistent racial disparities in survival after heart transplantation
    Vincent Liu
    Divisions of Pulmonary and Critical Care, Stanford University, CA, USA
    Circulation 123:1642-9. 2011
    ..Racial and ethnic disparities are well documented in many areas of health care, but have not been comprehensively evaluated among recipients of heart transplants...
  52. doi request reprint The relation between hospital procedure volume and complications of cardioverter-defibrillator implantation from the implantable cardioverter-defibrillator registry
    James V Freeman
    Stanford University School of Medicine, California, USA
    J Am Coll Cardiol 56:1133-9. 2010
    ..We sought to examine the relationship between hospital implantable cardioverter-defibrillator (ICD) implantation volume and procedural complications in a contemporary, representative population...
  53. ncbi request reprint Trends in hospital treatment of ventricular arrhythmias among Medicare beneficiaries, 1985 to 1995
    Kathryn M McDonald
    Health Research and Policy, and the Department of Medicine, Stanford University School of Medicine, Stanford, Calif, USA
    Am Heart J 144:413-21. 2002
    ..Treatment options for patients with ventricular arrhythmias have undergone major changes in the last 2 decades. Trends in use of invasive procedures, clinical outcomes, and expenditures have not been well documented...
  54. pmc Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, California 94304 1334, USA
    J Am Coll Cardiol 56:1552-63. 2010
    ..We sought to replicate the association between the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism (rs20455), and clinical coronary artery disease (CAD)...
  55. ncbi request reprint Insulin resistance independently predicts the progression of coronary artery calcification
    Keane K Lee
    Stanford University School of Medicine, Stanford, CA, USA
    Am Heart J 157:939-45. 2009
    ..Change in coronary artery calcification is a surrogate marker of subclinical coronary artery disease (CAD). In the only large prospective study, CAD risk factors predicted progression of coronary artery calcium (CAC)...
  56. pmc Right coronary wall CMR in the older asymptomatic advance cohort: positive remodeling and associations with type 2 diabetes and coronary calcium
    Masahiro Terashima
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    J Cardiovasc Magn Reson 12:75. 2010
    ..The purpose of the study was to evaluate coronary wall CMR in an asymptomatic older cohort...
  57. doi request reprint Cost-effectiveness of genetic testing in family members of patients with long-QT syndrome
    MARCO V PEREZ
    Center for Inherited Cardiovascular Disease, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA
    Circ Cardiovasc Qual Outcomes 4:76-84. 2011
    ..Genetic testing can identify mutations in 75% of patients with LQTS, but genetic testing of family members remains controversial...
  58. ncbi request reprint Patient preferences in coronary revascularization
    J Hornberger
    Departments of Health Research and Policy and of Medicine, Stanford University School of Medicine, CA, USA
    Am Heart J 137:1153-62. 1999
    ..This study was performed to assess patient preferences for consequences of 3 coronary revascularization procedures: angioplasty, conventional coronary bypass surgery, and minimally invasive coronary bypass surgery...
  59. doi request reprint Distribution of asymmetric dimethylarginine among 980 healthy, older adults of different ethnicities
    Karsten Sydow
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Clin Chem 56:111-20. 2010
    ..However, the majority of studies investigating the clinical role of ADMA were performed in European study populations with few individuals of other ethnicities...
  60. pmc Cost-effectiveness of preparticipation screening for prevention of sudden cardiac death in young athletes
    Matthew T Wheeler
    Stanford University, California 94305, USA
    Ann Intern Med 152:276-86. 2010
    ..Inclusion of 12-lead electrocardiography (ECG) in preparticipation screening of young athletes is controversial because of concerns about cost-effectiveness...
  61. doi request reprint Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trials
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA, USA
    Lancet 373:1190-7. 2009
    ..We undertook a collaborative analysis of data from randomised trials to assess whether the effects of the procedures on mortality are modified by patient characteristics...
  62. doi request reprint Incidental findings on cardiac multidetector row computed tomography among healthy older adults: prevalence and clinical correlates
    Jeremy R Burt
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Arch Intern Med 168:756-61. 2008
    ..Our objectives were to evaluate the prevalence of incidental findings discovered during cardiac MDCT scanning and to identify clinical variables associated with incidental findings...
  63. ncbi request reprint Facility factors dominate the ability to achieve target haemoglobin levels in haemodialysis patients
    Kevin E Chan
    Division of Nephrology, Stanford University School of Medicine, 300 Pasteur Drive, S161, Stanford, CA 94305 5114, USA
    Nephrol Dial Transplant 23:2948-56. 2008
    ..Our objective was to determine whether patient factors, processes of care and measures of erythropoietin (EPO) responsiveness were associated with successful anemia management at the individual patient level...
  64. ncbi request reprint Evidence-based use of cardiac procedures and devices
    Mark A Hlatky
    Donald W Reynolds Cardiovascular Clinical Research Center, Stanford University School of Medicine, Stanford, Calif, USA
    N Engl J Med 350:2126-8. 2004
  65. ncbi request reprint Physical and sexual function in women with chronic kidney disease
    Manjula Kurella
    Department of Medicine, University of California San Francisco, San Francisco, CA 94118 1211, USA
    Am J Kidney Dis 43:868-76. 2004
    ..Cross-sectional studies suggest an association between functional status and chronic kidney disease (CKD). Whether physical function deteriorates with progression of CKD is unknown...
  66. ncbi request reprint Differences in medical care and disease outcomes among black and white women with heart disease
    Ashish K Jha
    Division of General Medicine, San Francisco VA Medical Center, San Francisco, USA
    Circulation 108:1089-94. 2003
    ..We sought to evaluate differences in medical care and clinical outcomes among black and white women with established coronary artery disease...
  67. ncbi request reprint Comorbidity and outcome in patients with coronary artery disease
    Mark A Hlatky
    J Am Coll Cardiol 43:583-4. 2004
  68. ncbi request reprint Improvement in quality of life after radiofrequency ablation
    Mark A Hlatky
    Pacing Clin Electrophysiol 29:341-2. 2006
  69. ncbi request reprint Statin and beta-blocker therapy and the initial presentation of coronary heart disease
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, California 94612 2304, USA
    Ann Intern Med 144:229-38. 2006
    ..Patients who present with unstable coronary disease, such as acute myocardial infarction, may systematically differ from patients who present with relatively stable coronary disease, such as exertional angina...
  70. ncbi request reprint Cost-effectiveness of implantable cardioverter-defibrillators
    Gillian D Sanders
    Duke Clinical Research Institute, Duke University, Durham, NC 27715, USA
    N Engl J Med 353:1471-80. 2005
    ..We assessed the cost-effectiveness of the ICD in the populations represented in these primary-prevention trials...
  71. ncbi request reprint Conducting economic evaluations alongside multinational clinical trials: toward a research consensus
    Shelby D Reed
    Center for Clinical and Genetic Economics, Duke University Medical Centre, Durham, NC, USA
    Am Heart J 149:434-43. 2005
    ..Delineation of the various approaches to multinational economic evaluation may assist researchers, peer reviewers, journal editors, and decision makers in evaluating the strengths and limitations of particular studies...
  72. ncbi request reprint Life after a ventricular arrhythmia
    John Hsu
    Division of Research, Kaiser Permanente, Oakland, Calif 94611 5714, USA
    Am Heart J 144:404-12. 2002
    ..We evaluated patients' quality of life (QOL) and medical costs after hospitalization and treatment for their first episode of an LTVA...
  73. ncbi request reprint Medical economics and the assessment of value in cardiovascular medicine: Part II
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 106:626-30. 2002
  74. ncbi request reprint Medical economics and the assessment of value in cardiovascular medicine: Part I
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 106:516-20. 2002
  75. ncbi request reprint Cost-effectiveness of a conservative, ischemia-guided management strategy after non-Q-wave myocardial infarction: results of a randomized trial
    Paul G Barnett
    VA Palo Alto Health Care System, Palo Alto, Calif, USA
    Circulation 105:680-4. 2002
    ..The effects of these strategies on economic outcomes have not been established...
  76. ncbi request reprint Self-rated health among women with coronary disease: depression is as important as recent cardiovascular events
    Bernice Ruo
    Division of General Internal Medicine, Department of Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2927, USA
    Am Heart J 152:921.e1-7. 2006
    ..Our main objective was to clarify the association between depression and self-rated health using longitudinal data...
  77. ncbi request reprint Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts?
    Carlos Iribarren
    Kaiser Permanente Division of Research, Oakland, California 94612, USA
    J Am Coll Cardiol 48:1800-7. 2006
    ....
  78. ncbi request reprint Risk of sudden versus nonsudden cardiac death in patients with coronary artery disease
    Nathan Every
    Department of Biostatistics, Northwest Health Services Research and Development Center of Excellence, VA Puget Sound Healthcare System, University of Washington, Seattle, Wash, USA
    Am Heart J 144:390-6. 2002
    ..The goal of the present study was to evaluate the ability of clinical factors to distinguish the risks of sudden and nonsudden cardiac death...
  79. ncbi request reprint Cost-effectiveness of coronary artery bypass grafts versus percutaneous coronary intervention for revascularization of high-risk patients
    Kevin T Stroupe
    Cooperative Studies Program Coordinating Center, Hines VA Hospital, PO Box 5000 151H, Hines, IL 60141, USA
    Circulation 114:1251-7. 2006
    ..The present study examined the cost-effectiveness of PCI versus CABG for these high-risk patients...
  80. pmc Calcium, vitamin D supplementation, and physical function in the Women's Health Initiative
    Robert L Brunner
    University of Nevada School of Medicine, PMB 251, MS 145, Reno, NV 89557, USA
    J Am Diet Assoc 108:1472-9. 2008
    ..Now we examine whether the treatment affected self-reported physical functioning and objective measures of physical functioning...
  81. ncbi request reprint ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Cl
    Philip Greenland
    Circulation 115:402-26. 2007
  82. ncbi request reprint Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: Section 5: gender-related risk factors for ischemic heart disease
    Leslee J Shaw
    Circulation 109:e56-8. 2004
  83. ncbi request reprint Plasma leptin levels and coronary artery calcification in older adults
    Carlos Iribarren
    Kaiser Permanente, Division of Research, 2000 Broadway, Oakland, California 94612, USA
    J Clin Endocrinol Metab 92:729-32. 2007
    ..Leptin is associated with adiposity and insulin resistance and may play a direct role in vascular calcification. It is unclear, however, whether leptin is an independent predictor of atherosclerotic burden...
  84. pmc Depressive symptoms and health-related quality of life: the Heart and Soul Study
    Bernice Ruo
    Section of General Internal Medicine, Veterans Affairs Medical Center, San Francisco 94121, USA
    JAMA 290:215-21. 2003
    ..Little is known regarding the extent to which patient-reported health status, including symptom burden, physical limitation, and quality of life, is determined by psychosocial vs physiological factors among patients with chronic disease...
  85. ncbi request reprint Preventing tomorrow's sudden cardiac death today: part II: Translating sudden cardiac death risk assessment strategies into practice and policy
    Gillian D Sanders
    Duke Clinical Research Institute, Duke Medical Center, Durham, NC 27715, USA
    Am Heart J 153:951-9. 2007
    ....
  86. ncbi request reprint Health-related quality of life in patients with pulmonary arterial hypertension
    Shirin Shafazand
    The George Washington University, Washington Hospital Center, Washington, DC, USA
    Chest 126:1452-9. 2004
    ..This study describes HRQOL in a cohort of patients with PAH...
  87. ncbi request reprint A systematic review of the economic burden of chronic angina
    Matthew W Reynolds
    MetaWorks Inc, Medford, Massachusetts, USA
    Am J Manag Care 10:S347-57. 2004
    ..Chronic angina carries an economic burden because of symptom management, the risk of major cardiovascular events, and lost productivity. The level of these costs has not been systematically quantified...
  88. ncbi request reprint Effect of postmenopausal hormone therapy on coronary heart disease events after percutaneous transluminal coronary angioplasty
    Masroor A Khan
    Cardiology Division, The University of Texas Health Center, 11937 US Highway 271, Tyler, TX 75708, USA
    Am J Cardiol 91:989-91, A7. 2003
  89. ncbi request reprint Cost effectiveness of cardiac resynchronization therapy
    Mark A Hlatky
    J Am Coll Cardiol 46:2322-4. 2005
  90. doi request reprint ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline
    Andrew E Epstein
    Circulation 117:e350-408. 2008
  91. ncbi request reprint Coronary revascularization and quality of life
    Mark A Hlatky
    Am Heart J 148:5-6. 2004
  92. doi request reprint ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline
    Andrew E Epstein
    J Am Coll Cardiol 51:e1-62. 2008
  93. ncbi request reprint Integrating complementary medicine into cardiovascular medicine. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (Writing Committee to Develop an Expert Consensus Document on Complementary and In
    John H K Vogel
    J Am Coll Cardiol 46:184-221. 2005
  94. doi request reprint ACC/AHA/HRS 2008 Guidelines for device-based therapy of cardiac rhythm abnormalities
    Andrew E Epstein
    Heart Rhythm 5:e1-62. 2008
  95. ncbi request reprint Underuse of evidence-based therapies
    Mark A Hlatky
    Circulation 110:644-5. 2004
  96. ncbi request reprint ACC/AHA/NASPE 2002 guideline update for implantation of cardiac pacemakers and antiarrhythmia devices: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to
    Gabriel Gregoratos
    Circulation 106:2145-61. 2002

Research Grants1

  1. ECONOMIC OUTCOMES OF TREATMENT STRATEGIES IN BAR1-2
    Mark Hlatky; Fiscal Year: 2006
    ..The investigators further expect that this collaborative effort will translate into a new practical clinical paradigm that will be used for treatment of Type II diabetic patients. ..