Research Topics
Species | John P T HigginsSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
A DNA microarray survey of gene expression in normal human tissuesRadha Shyamsundar
Department of Pathology, Stanford University School of Medicine, 269 Campus Drive, CCSR 3245A, Stanford, CA 94305 5176, USA
Genome Biol 6:R22. 2005....
Expression of FKBP12 in benign and malignant vascular endothelium: an immunohistochemical study on conventional sections and tissue microarraysJohn P T Higgins
Department of Pathology, Stanford University School of Medicine, California, USA
Am J Surg Pathol 27:58-64. 2003..In addition, our findings may explain the toxic effects of FK506 on vascular endothelium of the kidney...
Recommendations for the reporting of surgically resected specimens of renal cell carcinoma: the Association of Directors of Anatomic and Surgical PathologyJohn P Higgins
Department of Pathology, Stanford University, Stanford, CA 94025, USA
Hum Pathol 40:456-63. 2009..The accompanying checklist will serve to ensure that all necessary details of the renal resection specimen are included in the surgical pathology report...
Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarrayJohn P T Higgins
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Am J Surg Pathol 31:673-80. 2007..We conclude that the detection of S100P and GATA3 protein expression may help distinguish urothelial carcinomas from other genitourinary neoplasms that enter into the differential diagnosis...
Intravenous Tamm-Horsfall protein polyps: report of a case in association with a hematoma that mimicked a renal neoplasmJohn P T Higgins
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Am J Kidney Dis 48:e67-71. 2006..Although the cause of the hematoma was not apparent, the association with striking intravenous polyps of THP is noteworthy because this represents the first association of intravenous THP polyps with a large intraparenchymal hematoma...
Gene array studies in renal neoplasiaJohn P T Higgins
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
ScientificWorldJournal 6:502-11. 2006..The purpose of this review will be to summarize these studies, to compare the results of the different studies, and to suggest future areas of investigation with a particular emphasis on clinically relevant advances...
Gene expression in the normal adult human kidney assessed by complementary DNA microarrayJohn P T Higgins
Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
Mol Biol Cell 15:649-56. 2004..The distinctive patterns of gene expression in discrete portions of the kidney may serve as a resource for further understanding of renal physiology and the molecular and cellular organization of the nephron...
Alteration of gene expression signatures of cortical differentiation and wound response in lethal clear cell renal cell carcinomasHongjuan Zhao
Department of Urology, Stanford University, Stanford, CA, USA
PLoS ONE 4:e6039. 2009..Our findings suggest that critical biological features of lethal ccRCC include loss of normal cortical differentiation and activation of programs associated with wound healing...
Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarrayJohn P T Higgins
Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
Am J Pathol 162:925-32. 2003..Characterization of renal cell carcinomas based on gene expression patterns provides a revised classification of these tumors and has the potential to supply significant biological and clinical insights...
Biochemical remission after resection of prostate cancer lung metastasisDebby H Chao
Department of Urology, Stanford University School of Medicine, Stanford, California, USA
Urology 63:584-5. 2004..We present a case of a solitary pulmonary recurrence of prostate cancer after radical prostatectomy that was resected, resulting in 12 years of biochemical remission without additional therapy...
The utility of PAX5 immunohistochemistry in the diagnosis of undifferentiated malignant neoplasmsKristin C Jensen
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Mod Pathol 20:871-7. 2007..Lastly, we have shown that the lack of its expression at the protein level in many epithelial and mesenchymal neoplasms renders PAX5 expression an extremely specific marker of the B lineage...
A 30-month-old child with acute renal failure due to primary renal cytotoxic T-cell lymphomaSrikanth Paladugu
Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA
Am J Surg Pathol 34:1066-70. 2010..We review the literature on primary renal lymphoma with an emphasis on T-lineage lymphomas and those that occur in children...
TMA-Combiner, a simple software tool to permit analysis of replicate cores on tissue microarraysChih Long Liu
Biological and Biomedical Sciences Program, Division of Medical Sciences, Harvard Medical School, Cambridge, MA 02138, USA
Mod Pathol 18:1641-8. 2005..This greatly facilitates analysis of tissue microarrays, particularly for users with large repositories of data, and may facilitate discovery of biological trends and help refine diagnostic accuracy of tissue markers in clinical samples...
