Brenna M Henn

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples
    Brenna M Henn
    23andMe, Inc, Mountain View, California, United States of America
    PLoS ONE 7:e34267. 2012
  2. pmc Y-chromosomal evidence of a pastoralist migration through Tanzania to southern Africa
    Brenna M Henn
    Department of Anthropology, Stanford University, Stanford, CA 94035 2117, USA
    Proc Natl Acad Sci U S A 105:10693-8. 2008
  3. doi request reprint Characterizing the time dependency of human mitochondrial DNA mutation rate estimates
    Brenna M Henn
    Department of Anthropology, Stanford University, USA
    Mol Biol Evol 26:217-30. 2009
  4. pmc Hunter-gatherer genomic diversity suggests a southern African origin for modern humans
    Brenna M Henn
    Department of Genetics, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 108:5154-62. 2011
  5. pmc Limited evidence for classic selective sweeps in African populations
    Julie M Granka
    Department of Biology, Stanford University, Stanford, California 94305, USA
    Genetics 192:1049-64. 2012
  6. pmc Genomic ancestry of North Africans supports back-to-Africa migrations
    Brenna M Henn
    Department of Genetics, Stanford University, Stanford, CA, USA
    PLoS Genet 8:e1002397. 2012
  7. ncbi request reprint African Y chromosome and mtDNA divergence provides insight into the history of click languages
    Alec Knight
    Department of Anthropological Sciences, Stanford University, Stanford, CA 94305, USA
    Curr Biol 13:464-73. 2003
  8. ncbi request reprint A tale of two haplotypes: the EDA2R/AR Intergenic region is the most divergent genomic segment between Africans and East Asians in the human genome
    Amanda M Casto
    Department of Genetics, Stanford University, Mail Stop 5120, Stanford, California 94305, USA
    Hum Biol 84:641-94. 2012
  9. pmc Sequencing Y chromosomes resolves discrepancy in time to common ancestor of males versus females
    G David Poznik
    Program in Biomedical Informatics, Stanford University School of Medicine, Stanford, CA, USA
    Science 341:562-5. 2013
  10. pmc Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe
    Martin Sikora
    Department of Genetics, Stanford University, Stanford, California, United States of America
    PLoS Genet 10:e1004353. 2014

Detail Information

Publications15

  1. pmc Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples
    Brenna M Henn
    23andMe, Inc, Mountain View, California, United States of America
    PLoS ONE 7:e34267. 2012
    ....
  2. pmc Y-chromosomal evidence of a pastoralist migration through Tanzania to southern Africa
    Brenna M Henn
    Department of Anthropology, Stanford University, Stanford, CA 94035 2117, USA
    Proc Natl Acad Sci U S A 105:10693-8. 2008
    ..Our Y-chromosomal evidence supports a demic diffusion model of pastoralism from eastern to southern Africa approximately 2,000 years ago...
  3. doi request reprint Characterizing the time dependency of human mitochondrial DNA mutation rate estimates
    Brenna M Henn
    Department of Anthropology, Stanford University, USA
    Mol Biol Evol 26:217-30. 2009
    ..Our findings suggest that human mtDNA estimates of dates of population and phylogenetic events should be adjusted in light of this time dependency of the mutation rate estimates...
  4. pmc Hunter-gatherer genomic diversity suggests a southern African origin for modern humans
    Brenna M Henn
    Department of Genetics, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 108:5154-62. 2011
    ..However, African hunter-gatherer populations continue to maintain the highest levels of genetic diversity in the world...
  5. pmc Limited evidence for classic selective sweeps in African populations
    Julie M Granka
    Department of Biology, Stanford University, Stanford, California 94305, USA
    Genetics 192:1049-64. 2012
    ..Additionally, population history can confound the interpretation of selection statistics, suggesting that greater care is needed in attributing broad genetic patterns to human adaptation...
  6. pmc Genomic ancestry of North Africans supports back-to-Africa migrations
    Brenna M Henn
    Department of Genetics, Stanford University, Stanford, CA, USA
    PLoS Genet 8:e1002397. 2012
    ..Our genomic data reveal an extraordinarily complex history of migrations, involving at least five ancestral populations, into North Africa...
  7. ncbi request reprint African Y chromosome and mtDNA divergence provides insight into the history of click languages
    Alec Knight
    Department of Anthropological Sciences, Stanford University, Stanford, CA 94305, USA
    Curr Biol 13:464-73. 2003
    ..Intriguingly, the language of the Hadzabe of eastern Africa, although not closely related to any other language, shares click consonants and accompaniments with languages of Khwe and San...
  8. ncbi request reprint A tale of two haplotypes: the EDA2R/AR Intergenic region is the most divergent genomic segment between Africans and East Asians in the human genome
    Amanda M Casto
    Department of Genetics, Stanford University, Mail Stop 5120, Stanford, California 94305, USA
    Hum Biol 84:641-94. 2012
    ..However, we also present evidence that this region is the target of selection in the form of positive selection on the α- and β-haplotypes and of purifying the selection against α/β recombinants. ..
  9. pmc Sequencing Y chromosomes resolves discrepancy in time to common ancestor of males versus females
    G David Poznik
    Program in Biomedical Informatics, Stanford University School of Medicine, Stanford, CA, USA
    Science 341:562-5. 2013
    ..Our findings suggest that, contrary to previous claims, male lineages do not coalesce significantly more recently than female lineages...
  10. pmc Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe
    Martin Sikora
    Department of Genetics, Stanford University, Stanford, California, United States of America
    PLoS Genet 10:e1004353. 2014
    ....
  11. pmc The genetic prehistory of southern Africa
    Joseph K Pickrell
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    Nat Commun 3:1143. 2012
    ..In addition, the East African Hadza and Sandawe derive a fraction of their ancestry from admixture with a population related to the Khoisan, supporting the hypothesis of an ancient link between southern and eastern Africa...
  12. pmc The great human expansion
    Brenna M Henn
    Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 109:17758-64. 2012
    ....
  13. pmc Exome capture from saliva produces high quality genomic and metagenomic data
    Jeffrey M Kidd
    Department of Genetics, Stanford University, Stanford, CA 94305, USA
    BMC Genomics 15:262. 2014
    ..However, thousands of samples have been previously collected from these cell types, and saliva collection has the advantage that it is a non-invasive and appropriate for a wide variety of research...
  14. pmc Demographic history and rare allele sharing among human populations
    Simon Gravel
    Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305 5120, USA
    Proc Natl Acad Sci U S A 108:11983-8. 2011
    ..Our results emphasize that replication of disease association for specific rare genetic variants across diverged populations must overcome both reduced statistical power because of rarity and higher population divergence...
  15. ncbi request reprint History of click-speaking populations of Africa inferred from mtDNA and Y chromosome genetic variation
    Sarah A Tishkoff
    Department of Biology, University of Maryland, USA
    Mol Biol Evol 24:2180-95. 2007
    ....