Brenna M Henn
Affiliation: Stanford University
- Cryptic distant relatives are common in both isolated and cosmopolitan genetic samplesBrenna M Henn
23andMe, Inc, Mountain View, California, United States of America
PLoS ONE 7:e34267. 2012....
- Y-chromosomal evidence of a pastoralist migration through Tanzania to southern AfricaBrenna M Henn
Department of Anthropology, Stanford University, Stanford, CA 94035 2117, USA
Proc Natl Acad Sci U S A 105:10693-8. 2008..Our Y-chromosomal evidence supports a demic diffusion model of pastoralism from eastern to southern Africa approximately 2,000 years ago...
- Characterizing the time dependency of human mitochondrial DNA mutation rate estimatesBrenna M Henn
Department of Anthropology, Stanford University, USA
Mol Biol Evol 26:217-30. 2009..Our findings suggest that human mtDNA estimates of dates of population and phylogenetic events should be adjusted in light of this time dependency of the mutation rate estimates...
- Hunter-gatherer genomic diversity suggests a southern African origin for modern humansBrenna M Henn
Department of Genetics, Stanford University, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 108:5154-62. 2011..However, African hunter-gatherer populations continue to maintain the highest levels of genetic diversity in the world...
- Limited evidence for classic selective sweeps in African populationsJulie M Granka
Department of Biology, Stanford University, Stanford, California 94305, USA
Genetics 192:1049-64. 2012..Additionally, population history can confound the interpretation of selection statistics, suggesting that greater care is needed in attributing broad genetic patterns to human adaptation...
- Genomic ancestry of North Africans supports back-to-Africa migrationsBrenna M Henn
Department of Genetics, Stanford University, Stanford, CA, USA
PLoS Genet 8:e1002397. 2012..Our genomic data reveal an extraordinarily complex history of migrations, involving at least five ancestral populations, into North Africa...
- African Y chromosome and mtDNA divergence provides insight into the history of click languagesAlec Knight
Department of Anthropological Sciences, Stanford University, Stanford, CA 94305, USA
Curr Biol 13:464-73. 2003..Intriguingly, the language of the Hadzabe of eastern Africa, although not closely related to any other language, shares click consonants and accompaniments with languages of Khwe and San...
- Sequencing Y chromosomes resolves discrepancy in time to common ancestor of males versus femalesG David Poznik
Program in Biomedical Informatics, Stanford University School of Medicine, Stanford, CA, USA
Science 341:562-5. 2013..Our findings suggest that, contrary to previous claims, male lineages do not coalesce significantly more recently than female lineages...
- The genetic prehistory of southern AfricaJoseph K Pickrell
Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
Nat Commun 3:1143. 2012..In addition, the East African Hadza and Sandawe derive a fraction of their ancestry from admixture with a population related to the Khoisan, supporting the hypothesis of an ancient link between southern and eastern Africa...
- A tale of two haplotypes: the EDA2R/AR Intergenic region is the most divergent genomic segment between Africans and East Asians in the human genomeAmanda M Casto
Department of Genetics, Stanford University, Mail Stop 5120, Stanford, California 94305, USA
Hum Biol 84:641-94. 2012..However, we also present evidence that this region is the target of selection in the form of positive selection on the α- and β-haplotypes and of purifying the selection against α/β recombinants. ..
- The great human expansionBrenna M Henn
Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 109:17758-64. 2012....
- Demographic history and rare allele sharing among human populationsSimon Gravel
Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305 5120, USA
Proc Natl Acad Sci U S A 108:11983-8. 2011..Our results emphasize that replication of disease association for specific rare genetic variants across diverged populations must overcome both reduced statistical power because of rarity and higher population divergence...
- History of click-speaking populations of Africa inferred from mtDNA and Y chromosome genetic variationSarah A Tishkoff
Department of Biology, University of Maryland, USA
Mol Biol Evol 24:2180-95. 2007....