VICTOR HENDERSON

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi The neurology of menopause
    Victor W Henderson
    Department of Health Research, Stanford University, Stanford, California 94305 5405, USA
    Neurologist 12:149-59. 2006
  2. ncbi Effects of endogenous and exogenous estrogen exposures in midlife and late-life women on episodic memory and executive functions
    V W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University, Stanford, CA, USA
    Neuroscience 191:129-38. 2011
  3. ncbi Estrogen-containing hormone therapy and Alzheimer's disease risk: understanding discrepant inferences from observational and experimental research
    V W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University, CA 94305, USA
    Neuroscience 138:1031-9. 2006
  4. ncbi Postmenopausal hormone therapy and Alzheimer's disease risk: interaction with age
    V W Henderson
    Stanford University School of Medicine, 259 Campus Drive, HRP Redwood Building, Stanford University, Stanford, CA 94305 5405, USA
    J Neurol Neurosurg Psychiatry 76:103-5. 2005
  5. ncbi Surgical versus natural menopause: cognitive issues
    Victor W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University, Stanford, CA 94305, USA
    Menopause 14:572-9. 2007
  6. ncbi Alexia and agraphia: contrasting perspectives of J.-M. Charcot and J. Hughlings Jackson
    Victor W Henderson
    Department of Health Research and Policy, Stanford University, 259 Campus Drive, MC 5405, Stanford, CA 94305 5405, USA
    Neurology 70:391-400. 2008
  7. ncbi Cognitive changes after menopause: influence of estrogen
    Victor W Henderson
    Departmentsof Health Research and Policy Epidemiology, Stanford University, Stanford, California 94305 5405, USA
    Clin Obstet Gynecol 51:618-26. 2008
  8. ncbi Menopause, cognitive ageing and dementia: practice implications
    Victor W Henderson
    Departments of Health Research and Policy Epidemiology and of Neurology and Neurological Sciences, Stanford University, 259 Campus Drive, Stanford, CA 94305 5405, USA
    Menopause Int 15:41-4. 2009
  9. ncbi Estrogens, episodic memory, and Alzheimer's disease: a critical update
    Victor W Henderson
    Departments of Health Research and Policy Epidemiology and of Neurology and Neurological Sciences, Stanford University, Stanford, California 94305 5405, USA
    Semin Reprod Med 27:283-93. 2009
  10. ncbi Chapter 17: cognitive assessment in neurology
    Victor W Henderson
    Departments of Health Research and Policy Epidemiology and Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305 5405, USA
    Handb Clin Neurol 95:235-56. 2010

Research Grants

  1. Raloxifene in Women with AD: Randomized Controlled Trial
    VICTOR HENDERSON; Fiscal Year: 2007
  2. Tai Chi and Guided Autobiography for Remediation of Age-Related Cognitive Decline
    Victor W Henderson; Fiscal Year: 2010

Detail Information

Publications37

  1. ncbi The neurology of menopause
    Victor W Henderson
    Department of Health Research, Stanford University, Stanford, California 94305 5405, USA
    Neurologist 12:149-59. 2006
    ..The objective of this article is to increase neurologists' awareness of the relation between menopause and neurologic illness...
  2. ncbi Effects of endogenous and exogenous estrogen exposures in midlife and late-life women on episodic memory and executive functions
    V W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University, Stanford, CA, USA
    Neuroscience 191:129-38. 2011
    ..This article is part of a Special Issue entitled: Neuroactive Steroids: Focus on Human Brain...
  3. ncbi Estrogen-containing hormone therapy and Alzheimer's disease risk: understanding discrepant inferences from observational and experimental research
    V W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University, CA 94305, USA
    Neuroscience 138:1031-9. 2006
    ....
  4. ncbi Postmenopausal hormone therapy and Alzheimer's disease risk: interaction with age
    V W Henderson
    Stanford University School of Medicine, 259 Campus Drive, HRP Redwood Building, Stanford University, Stanford, CA 94305 5405, USA
    J Neurol Neurosurg Psychiatry 76:103-5. 2005
    ..However, our observational findings are consistent with the view that HT may protect younger women from AD or reduce the risk of early onset forms of AD, or that HT used during the early postmenopause may reduce AD risk...
  5. ncbi Surgical versus natural menopause: cognitive issues
    Victor W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University, Stanford, CA 94305, USA
    Menopause 14:572-9. 2007
    ..Studies of estrogen-containing hormone therapy are relevant to this issue...
  6. ncbi Alexia and agraphia: contrasting perspectives of J.-M. Charcot and J. Hughlings Jackson
    Victor W Henderson
    Department of Health Research and Policy, Stanford University, 259 Campus Drive, MC 5405, Stanford, CA 94305 5405, USA
    Neurology 70:391-400. 2008
    ..To evaluate 19th-century concepts of cerebral localization for complex mental activities, focusing on alexia and agraphia in published writings of Jean-Martin Charcot (1825-1893) and John Hughlings Jackson (1835-1911)...
  7. ncbi Cognitive changes after menopause: influence of estrogen
    Victor W Henderson
    Departmentsof Health Research and Policy Epidemiology, Stanford University, Stanford, California 94305 5405, USA
    Clin Obstet Gynecol 51:618-26. 2008
    ..Observational findings of reduced Alzheimer risk may reflect early hormone use in younger women, or findings may be biased. Cognitive effects of selective estrogen receptor modulators are not yet well studied...
  8. ncbi Menopause, cognitive ageing and dementia: practice implications
    Victor W Henderson
    Departments of Health Research and Policy Epidemiology and of Neurology and Neurological Sciences, Stanford University, 259 Campus Drive, Stanford, CA 94305 5405, USA
    Menopause Int 15:41-4. 2009
    ..Observational studies imply a protective association consistent with the so-called critical window hypothesis, but these findings could be biased. Clinical practice implications are presented...
  9. ncbi Estrogens, episodic memory, and Alzheimer's disease: a critical update
    Victor W Henderson
    Departments of Health Research and Policy Epidemiology and of Neurology and Neurological Sciences, Stanford University, Stanford, California 94305 5405, USA
    Semin Reprod Med 27:283-93. 2009
    ..Selective estrogen receptor modulators have the potential to affect cognitive outcomes and also merit additional study...
  10. ncbi Chapter 17: cognitive assessment in neurology
    Victor W Henderson
    Departments of Health Research and Policy Epidemiology and Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305 5405, USA
    Handb Clin Neurol 95:235-56. 2010
    ..Advances in clinical psychology, neurology, and the cognate clinical neurosciences continue to enrich assessment options...
  11. ncbi Chapter 37: alexia and agraphia
    Victor W Henderson
    Department of Health Research and Policy Epidemiology and Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305 5405, USA
    Handb Clin Neurol 95:583-601. 2010
    ..Other analyses focused on error types that defined new clinical syndromes (e.g. deep dyslexia) and provided evidence for cognitive modularity...
  12. ncbi Action of estrogens in the aging brain: dementia and cognitive aging
    Victor W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Biochim Biophys Acta 1800:1077-83. 2010
    ..Menopause is associated with sharp declines in concentrations of circulating estrogens. This change in hormone milieu has the potential to affect brain functions relevant to dementia and cognitive aging...
  13. ncbi Aging, estrogens, and episodic memory in women
    Victor W Henderson
    Departments of Health Research and Policy Epidemiology, and of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305 5405, USA
    Cogn Behav Neurol 22:205-14. 2009
    ..To review the relation in midlife and beyond between estrogen exposures and episodic memory in women...
  14. ncbi Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy
    Victor W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University, Stanford, CA, USA
    Prog Brain Res 182:77-96. 2010
    ..Research needs include better predictors of adverse cognitive outcomes, biomarkers for risks associated with hormone therapy, and tools for monitoring brain function and disease progression...
  15. ncbi Gonadal hormones and cognitive aging: a midlife perspective
    Victor W Henderson
    Stanford University School of Medicine, MC 5405, Stanford, CA 94305 5405, USA
    Womens Health (Lond Engl) 7:81-93. 2011
    ..Effects of natural menopause on other cognitive domains, cognitive consequences of surgical menopause and late-life cognitive consequences of midlife hormonal exposures are less well understood and merit continued study...
  16. ncbi Menopause and disorders of the central nervous system
    V W Henderson
    Department of Health Research and Policy Epidemiology, Stanford University, 259 Campus Drive, Stanford, CA 94305 5405, USA
    Minerva Ginecol 57:579-92. 2005
    ....
  17. ncbi Hormone therapy, timing of initiation, and cognition in women aged older than 60 years: the REMEMBER pilot study
    Alastair H MacLennan
    Department of Obstetrics and Gynaecology, Stanford University, CA, USA
    Menopause 13:28-36. 2006
    ....
  18. ncbi Better preservation of memory span relative to supraspan immediate recall in Alzheimer's disease
    Barbara J Cherry
    Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Neuropsychologia 40:846-52. 2002
    ..Results indicate that AD patients are specifically vulnerable to information overload inherent in the supraspan task, a view consistent with the perspective that AD is characterized by prominent disturbances in working memory...
  19. ncbi Hormone therapy and risk of Alzheimer disease: a critical time
    Susan M Resnick
    JAMA 288:2170-2. 2002
  20. ncbi Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial
    Stephen R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    JAMA 289:2663-72. 2003
    ..On July 8, 2002, the estrogen plus progestin therapy in the WHI trial was discontinued because of certain increased health risks for women...
  21. ncbi Testosterone and Alzheimer disease: is it men's turn now?
    Victor W Henderson
    Neurology 62:170-1. 2004
  22. ncbi Normative verbal and non-verbal memory test scores for Australian women aged 56-67
    Margaret S Clark
    Office for Gender and Health, Charles Connibere Building, Royal Melbourne Hospital, Parkville, 3050, Australia
    Aust N Z J Psychiatry 38:532-40. 2004
    ..To establish normative data for tests of verbal and non-verbal memory for midlife Australian-born women, and in so doing investigate factors which contribute to variation in test performance...
  23. ncbi Metabolic syndrome and cognitive function in healthy middle-aged and older adults without diabetes
    Nicole M Gatto
    Department of Preventive Medicine, USC Keck School of Medicine, Los Angeles, CA 90089 9010, USA
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 15:627-41. 2008
    ..We examined the cross-sectional association between MetS and six areas of cognitive function in healthy cognitively intact adults without diabetes (n = 853, mean age 61 years) randomized in two intervention trials...
  24. ncbi Estrogen and cognition, with a focus on Alzheimer's disease
    Joann V Pinkerton
    Department of Obstetrics and Gynecology, University of Virginia Health System, Midlife Health Center, 2955 Ivy Road Suite 104, Charlottesville, VA 22903, USA
    Semin Reprod Med 23:172-9. 2005
    ....
  25. ncbi Effect of raloxifene on prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial
    Kristine Yaffe
    Department of Psychiatry, University of California, San Francisco, Box 181, 4150 Clement St, San Francisco, CA 94121, USA
    Am J Psychiatry 162:683-90. 2005
    ..This investigation examined whether raloxifene, a selective estrogen receptor modulator, affects the risk for Alzheimer's disease...
  26. ncbi The Semantic Object Retrieval Test (SORT) in amnestic mild cognitive impairment
    Michael A Kraut
    Department of Radiology, Division of Neuroradiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cogn Behav Neurol 20:62-7. 2007
    ..Between 10% and 15% of patients with the amnestic variety of Mild Cognitive Impairment (MCI) convert to Alzheimer disease (AD) per year...
  27. ncbi Dementia, butterfly ballots, and voter competence
    Victor W Henderson
    Neurology 58:995-6. 2002
  28. ncbi White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study
    George Bartzokis
    Department of Neurology, Alzheimer s Disease Center, University of California, Los Angeles, 710 Westwood Plaza, Room 2 238, Los Angeles, CA 90095 1769, USA
    Arch Neurol 60:393-8. 2003
    ..6 years and then declines. Postmortem evidence indicates that the structural integrity of myelin sheaths deteriorates during normal aging, especially in late myelinating regions such as the frontal lobes...
  29. ncbi DHEA for Alzheimer's disease: a modest showing by a superhormone
    David Knopman
    Neurology 60:1060-1. 2003
  30. ncbi Only a matter of time? Hormone therapy and cognition
    Victor W Henderson
    Menopause 12:1-3. 2005
  31. ncbi Isoflavones: food for thoughtful consideration
    Victor W Henderson
    Menopause 10:189-90. 2003
  32. ncbi Preventing cognitive decline in usual aging
    Mark A Espeland
    Arch Intern Med 166:2433-4. 2006
  33. ncbi Hormone therapy and Alzheimer's disease: benefit or harm?
    Victor W Henderson
    Donald W Reynolda Center on Aging, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Expert Opin Pharmacother 5:389-406. 2004
    ..g., initiation during the menopausal transition or early postmenopause versus initiation during the late postmenopause)...
  34. ncbi The Semantic Object Retrieval Test (SORT) in normal aging and Alzheimer disease
    Michael A Kraut
    Department of Radiology, Division of Neuroradiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cogn Behav Neurol 19:177-84. 2006
    ..The task detected semantic memory deficits in approximately half of patients with mild-moderate AD, which is comparable to other studies assessing semantic deficits in AD with less specific measures...
  35. ncbi Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society
    Wulf H Utian
    Menopause 15:584-602. 2008
    ..The benefit-risk ratio for menopausal HT is favorable close to menopause but decreases with aging and with time since menopause in previously untreated women...
  36. ncbi Telephone word-list recall tested in the rural aging and memory study: two parallel versions for the TICS-M
    Eva Hogervorst
    Department of Geriatrics, Donald W Reynolds Center on Aging, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Int J Geriatr Psychiatry 19:875-80. 2004
    ..We aimed to investigate the usefulness of three parallel versions of ten-item word list recall tasks administered by telephone...
  37. ncbi A population-based study of depressed mood in middle-aged, Australian-born women
    Lorraine Dennerstein
    Office for Gender and Health, Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia
    Menopause 11:563-8. 2004
    ..There has been controversy about the relationship between menopause and depression. This study utilizes a unique prospective population-based data set of middle-aged, Australian-born women to identify determinants of depressed mood...

Research Grants5

  1. Raloxifene in Women with AD: Randomized Controlled Trial
    VICTOR HENDERSON; Fiscal Year: 2007
    ..It is anticipated that findings from this pilot study will provide useful guidance to plan and conduct future studies of raloxifene in women with mild to moderate symptoms of dementia due to AD. ..
  2. Tai Chi and Guided Autobiography for Remediation of Age-Related Cognitive Decline
    Victor W Henderson; Fiscal Year: 2010
    ....