Raphael Guzman

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Use of the NeuroBalloon catheter for endoscopic third ventriculostomy
    Raphael Guzman
    Division of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Stanford University School of Medicine, Stanford, CA 94305 5327, USA
    J Neurosurg Pediatr 11:302-6. 2013
  2. doi request reprint Timing of intra-arterial neural stem cell transplantation after hypoxia-ischemia influences cell engraftment, survival, and differentiation
    Sahar Rosenblum
    Department of Neurosurgery, Stanford University, 300 Pasteur Drive R211, Stanford, CA 94305 5327 or
    Stroke 43:1624-31. 2012
  3. doi request reprint Direct bypass techniques for the treatment of pediatric moyamoya disease
    Raphael Guzman
    Division of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Stanford University School of Medicine, 300 Pasteur Drive, R211, Stanford, CA 94305 5327, USA
    Neurosurg Clin N Am 21:565-73. 2010
  4. doi request reprint Fronto-orbital advancement using an en bloc frontal bone craniectomy
    Raphael Guzman
    Division of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Stanford University School of Medicine, Stanford, California 94305 5327, USA
    Neurosurgery 68:68-74. 2011
  5. doi request reprint Clinical outcome after 450 revascularization procedures for moyamoya disease. Clinical article
    Raphael Guzman
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5487, USA
    J Neurosurg 111:927-35. 2009
  6. pmc Intraoperative blood flow analysis of direct revascularization procedures in patients with moyamoya disease
    Marco Lee
    Department of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, California 94305, USA
    J Cereb Blood Flow Metab 31:262-74. 2011
  7. doi request reprint Management of pediatric intracranial arteriovenous malformations: experience with multimodality therapy
    Tim E Darsaut
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5325, USA
    Neurosurgery 69:540-56; discussion 556. 2011
  8. pmc The CCR2/CCL2 interaction mediates the transendothelial recruitment of intravascularly delivered neural stem cells to the ischemic brain
    Robert H Andres
    Department of Neurosurgery, Stanford Stroke Center, Stanford University, School of Medicine, 300 Pasteur Drive R211, Stanford, CA 94305 5327, USA
    Stroke 42:2923-31. 2011
  9. doi request reprint Biodistribution of neural stem cells after intravascular therapy for hypoxic-ischemia
    Arjun V Pendharkar
    Department of Neurosurgery, Stanford University, School of Medicine, Stanford, CA 94305 5327, USA
    Stroke 41:2064-70. 2010
  10. doi request reprint Pathophysiology and genetic factors in moyamoya disease
    Achal S Achrol
    Departments of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, California 94305 5487, USA
    Neurosurg Focus 26:E4. 2009

Collaborators

Detail Information

Publications41

  1. doi request reprint Use of the NeuroBalloon catheter for endoscopic third ventriculostomy
    Raphael Guzman
    Division of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Stanford University School of Medicine, Stanford, CA 94305 5327, USA
    J Neurosurg Pediatr 11:302-6. 2013
    ..1%, and the risk of balloon rupture was less than 2%. The authors found that the placement and deployment of this balloon catheter facilitate the creation of an adequate ventriculostomy in a few simple steps...
  2. doi request reprint Timing of intra-arterial neural stem cell transplantation after hypoxia-ischemia influences cell engraftment, survival, and differentiation
    Sahar Rosenblum
    Department of Neurosurgery, Stanford University, 300 Pasteur Drive R211, Stanford, CA 94305 5327 or
    Stroke 43:1624-31. 2012
    ..Intra-arterial neural stem cell (NSC) transplantation shows promise as a minimally invasive therapeutic option for stroke. We assessed the effect of timing of transplantation on cell engraftment, survival, and differentiation...
  3. doi request reprint Direct bypass techniques for the treatment of pediatric moyamoya disease
    Raphael Guzman
    Division of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Stanford University School of Medicine, 300 Pasteur Drive, R211, Stanford, CA 94305 5327, USA
    Neurosurg Clin N Am 21:565-73. 2010
    ..Revascularization surgery seems to be effective in preventing stroke in moyamoya, with direct techniques providing durable protection when performed at experienced centers...
  4. doi request reprint Fronto-orbital advancement using an en bloc frontal bone craniectomy
    Raphael Guzman
    Division of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Stanford University School of Medicine, Stanford, California 94305 5327, USA
    Neurosurgery 68:68-74. 2011
    ..Fronto-orbital advancement is a procedure commonly performed in craniofacial centers for coronal and metopic suture synostosis. Several variations of the technique have been reported...
  5. doi request reprint Clinical outcome after 450 revascularization procedures for moyamoya disease. Clinical article
    Raphael Guzman
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5487, USA
    J Neurosurg 111:927-35. 2009
    ..They report on a consecutive series of patients treated for MMD and detail their demographics, clinical characteristics, and long-term surgical outcomes...
  6. pmc Intraoperative blood flow analysis of direct revascularization procedures in patients with moyamoya disease
    Marco Lee
    Department of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, California 94305, USA
    J Cereb Blood Flow Metab 31:262-74. 2011
    ..6 ± 5.6 mL/min; P=0.047) compared with controls. Other flow and vessel dimension data are presented to elucidate the hemodynamic changes related to the vasculopathy and subsequent to surgical intervention...
  7. doi request reprint Management of pediatric intracranial arteriovenous malformations: experience with multimodality therapy
    Tim E Darsaut
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5325, USA
    Neurosurgery 69:540-56; discussion 556. 2011
    ..Successful management of pediatric arteriovenous malformations (AVMs) often requires a balanced application of embolization, surgery, and radiosurgery...
  8. pmc The CCR2/CCL2 interaction mediates the transendothelial recruitment of intravascularly delivered neural stem cells to the ischemic brain
    Robert H Andres
    Department of Neurosurgery, Stanford Stroke Center, Stanford University, School of Medicine, 300 Pasteur Drive R211, Stanford, CA 94305 5327, USA
    Stroke 42:2923-31. 2011
    ..However, the mechanisms underlying the process of transendothelial recruitment remain largely unknown. Here we describe the critical role of the chemokine CCL2 and its receptor CCR2 in targeted homing of NSC after ischemia...
  9. doi request reprint Biodistribution of neural stem cells after intravascular therapy for hypoxic-ischemia
    Arjun V Pendharkar
    Department of Neurosurgery, Stanford University, School of Medicine, Stanford, CA 94305 5327, USA
    Stroke 41:2064-70. 2010
    ..We studied the biodistribution and efficiency of targeted central nervous system delivery comparing intravenous and intra-arterial (IA) administration of neural stem cells after brain ischemia...
  10. doi request reprint Pathophysiology and genetic factors in moyamoya disease
    Achal S Achrol
    Departments of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, California 94305 5487, USA
    Neurosurg Focus 26:E4. 2009
    ....
  11. doi request reprint Sex differences in clinical presentation and treatment outcomes in Moyamoya disease
    Nadia Khan
    Department of Neurosurgery, Stanford Stroke Center, Stanford University School of Medicine, California 94305 5487, USA
    Neurosurgery 71:587-93; discussion 593. 2012
    ..Moyamoya (MM) disease is an idiopathic steno-occlusive angiopathy occurring more frequently in females...
  12. pmc Neural progenitor cells regulate microglia functions and activity
    Kira I Mosher
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA
    Nat Neurosci 15:1485-7. 2012
    ..Thus, neural precursor cells may not only be shaped by microglia, but also regulate microglia functions and activity...
  13. pmc Intra-arterial injection of neural stem cells using a microneedle technique does not cause microembolic strokes
    Joshua Y Chua
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    J Cereb Blood Flow Metab 31:1263-71. 2011
    ..0001) and ischemic changes on diffusion weighted imaging. With an appropriate technique, reduction in CBF and microstrokes do not occur with IA transplantation of NPCs...
  14. doi request reprint Positron emission tomography imaging of poststroke angiogenesis
    Weibo Cai
    The Molecular Imaging Program at Stanford, Department of Radiology, Stanford University, Stanford, CA, USA
    Stroke 40:270-7. 2009
    ..In this study, we imaged VEGFR expression with positron emission tomography (PET) to noninvasively analyze poststroke angiogenesis...
  15. doi request reprint The evolution of cerebral revascularization surgery
    Melanie G Hayden
    Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305, USA
    Neurosurg Focus 26:E17. 2009
    ..Recent innovations, including modern techniques to monitor cerebral blood flow, microanastomosis techniques, and ongoing trials that play an important role in the evolution of this field are also evaluated...
  16. doi request reprint Pathogenesis and radiobiology of brain arteriovenous malformations: implications for risk stratification in natural history and posttreatment course
    Achal S Achrol
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5487, USA
    Neurosurg Focus 26:E9. 2009
    ....
  17. pmc Quantitative hemodynamic studies in moyamoya disease: a review
    Marco Lee
    Department of Neurosurgery, Stanford Stroke Center, Stanford, California, USA
    Neurosurg Focus 26:E5. 2009
    ..The authors review the current knowledge of CBF in this group of patients and the role each main quantitative method has played in evaluating them, both in the disease state and after surgical intervention...
  18. doi request reprint In vivo neural stem cell imaging: current modalities and future directions
    Atul Gera
    Department of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, 300 Pasteur Drive, R2111, Stanford, CA 94305 95327, USA
    Regen Med 5:73-86. 2010
    ..In this paper, we review contemporary methods for in vivo neural stem cell imaging, including MRI, PET and optical imaging techniques...
  19. doi request reprint Intraoperative hypothermia during vascular neurosurgical procedures
    Raymond Choi
    Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305 5327, USA
    Neurosurg Focus 26:E24. 2009
    ....
  20. pmc Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI
    Raphael Guzman
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive R200, Stanford, CA 94305 5327, USA
    Proc Natl Acad Sci U S A 104:10211-6. 2007
    ..Knowledge of migration patterns and implementation of noninvasive stem cell tracking might help to improve the design of future clinical neural stem cell transplantation...
  21. doi request reprint Successful treatment of severe cerebral vasospasm following hemorrhage of an arteriovenous malformation. Case report
    Arjun V Pendharkar
    Divisions of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Standford School of Medicine, Stanford, California 94305 5327, USA
    J Neurosurg Pediatr 4:266-9. 2009
    ....
  22. doi request reprint Vein of Galen malformation
    Stanley Hoang
    Department of Neurosurgery, Division of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Stanford University School of Medicine, Stanford, California, USA
    Neurosurg Focus 27:E8. 2009
    ..In this paper the authors review the developmental mechanisms, clinical pathophysiology, and the available data on the management and outcome of the disease...
  23. ncbi request reprint Neural progenitor cells transplanted into the uninjured brain undergo targeted migration after stroke onset
    Raphael Guzman
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5327, USA
    J Neurosci Res 86:873-82. 2008
    ..We find that transplanted NPCs that are latent can be activated in response to stroke and exhibit directional migration into the parenchyma, similar to endogenous neural NPCs, without a niche environment...
  24. doi request reprint Intracarotid injection of fluorescence activated cell-sorted CD49d-positive neural stem cells improves targeted cell delivery and behavior after stroke in a mouse stroke model
    Raphael Guzman
    Department of Neurosurgery and Stanford Stroke Center, Stanford University School of Medicine, Stanford, CA 94305 5327, USA
    Stroke 39:1300-6. 2008
    ..We hypothesize that enriching for NSCs that express CD49d and injecting them into the carotid artery would improve targeted cell delivery to the injured brain...
  25. doi request reprint Cell replacement therapy for intracerebral hemorrhage
    Robert H Andres
    Department of Neurosurgery, Stanford University Medical Center, Stanford, California, USA
    Neurosurg Focus 24:E16. 2008
    ..In this review, the authors outline the recent advances in the basic science of treatment strategies for ICH...
  26. doi request reprint Potential of adult neural stem cells in stroke therapy
    Robert H Andres
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, R211, Stanford, CA 94305 5327, USA
    Regen Med 3:893-905. 2008
    ..This review describes up-to-date experimental concepts using adult neural stem cells for the treatment of stroke...
  27. doi request reprint Using bioabsorbable fixation systems in the treatment of pediatric skull deformities leads to good outcomes and low morbidity
    Melanie G Hayden Gephart
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94304, USA
    Childs Nerv Syst 29:297-301. 2013
    ..Likewise, long-term follow-up in this clinical cohort has not previously been described...
  28. doi request reprint Trends in the diagnosis and treatment of pediatric primary spinal cord tumors
    Melanie G Hayden Gephart
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5327, USA
    J Neurosurg Pediatr 10:555-9. 2012
    ..The authors evaluated trends in the diagnosis and treatment of PSCTs using a nationwide database...
  29. doi request reprint Application of diffusion tensor tractography in pediatric optic pathway glioma
    Robert M Lober
    Departments of Neurosurger, Division of Pediatric NeurosurgeryStanford University School of Medicine, Stanford, California 94305 5327, USA
    J Neurosurg Pediatr 10:273-80. 2012
    ..The authors investigated the role of diffusion tensor (DT) tractography in assessing the location of visual pathway fibers in the presence of tumor...
  30. doi request reprint Intravascular cell replacement therapy for stroke
    Raphael Guzman
    Department of Neurosurgery, Stanford University Medical Center, Stanford, California, USA
    Neurosurg Focus 24:E15. 2008
    ..They also review current concepts of in vivo imaging and tracking of stem cells after stroke...
  31. doi request reprint Endovascular and surgical treatment of spinal dural arteriovenous fistulas
    Robert H Andres
    Department of Neurosurgery, University of Berne, Inselspital, Berne, Switzerland
    Neuroradiology 50:869-76. 2008
    ..The aim of this retrospective study was to evaluate the clinical outcome of patients with spinal dural arteriovenous fistulas (SDAVFs) that were treated with surgery, catheter embolization, or surgery after incomplete embolization...
  32. doi request reprint Primary pediatric skull tumors
    Melanie G Hayden Gephart
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94305, USA
    Pediatr Neurosurg 47:198-203. 2011
    ..To review the pathological distribution of pediatric primary skull tumors, and to determine the diagnostic value of lesion location, patient age and lesion size...
  33. doi request reprint Moyamoya disease in pediatric patients: outcomes of neurosurgical interventions
    Anand Veeravagu
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
    Neurosurg Focus 24:E16. 2008
    ..Additional, larger studies are needed to determine the advantages and disadvantages of the different techniques for the pediatric age group...
  34. pmc Absence of CCL2 is sufficient to restore hippocampal neurogenesis following cranial irradiation
    Star W Lee
    Stanford University, Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA, USA
    Brain Behav Immun 30:33-44. 2013
    ..This identifies CCL2 signaling as a potential clinical target for moderating the long-term defects in neural stem cell function following cranial radiation in children...
  35. ncbi request reprint Cell transplantation therapy for stroke
    Tonya Bliss
    Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA
    Stroke 38:817-26. 2007
    ..In this review we summarize these studies, discuss potential mechanisms of action of the transplanted cells, and emphasize the need to determine parameters that are critical for transplantation success...
  36. doi request reprint Langerhans cell histiocytosis in a 5-month-old presenting with biparietal masses
    Katie L Pricola
    Division of Pediatric Neurosurgery, Lucile Packard Children s Hospital, Stanford University School of Medicine, Stanford, California 94305 5327, USA
    J Neurosurg Pediatr 6:393-7. 2010
    ....
  37. doi request reprint Recurring osteoma within a calcium phosphate bone cement cranioplasty: case report
    Melanie G Hayden
    Department of Neurosurgery, Stanford University, Stanford, California, USA
    Neurosurgery 64:E775-6; discussion E776. 2009
    ..We present a unique case of a recurrent osteoma within a cranioplasty performed with calcium phosphate bone cement...
  38. ncbi request reprint Cerebral perfusion imaging in vasospasm
    Shivanand P Lad
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
    Neurosurg Focus 21:E7. 2006
    ....
  39. doi request reprint Perioperative posterior reversible encephalopathy syndrome in 2 pediatric neurosurgery patients with brainstem ependymoma
    Melanie G Hayden Gephart
    Department of Neurosurgery, Stanford University Hospital and Clinics, Stanford, California 94305 5327, USA
    J Neurosurg Pediatr 7:235-7. 2011
    ..An awareness of PRES in similar scenarios will aid in the prevention, diagnosis, and treatment of pediatric neurosurgery patients with this syndrome...
  40. doi request reprint Multimodality treatment of posterior fossa arteriovenous malformations
    Michael E Kelly
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305 5327, USA
    J Neurosurg 108:1152-61. 2008
    ..The authors present their experience with multimodality treatment of 76 posterior fossa AVMs, with an emphasis on Spetzler-Martin Grades III-V AVMs...
  41. ncbi request reprint Propionibacterium acnes infections after cranial neurosurgery
    Michael E Kelly
    Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305 5327, USA
    Can J Neurol Sci 33:292-5. 2006
    ..We reviewed our experience with the occurrence and management of P. acnes infections after cranial neurosurgical procedures over a five-year period...